iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089349

Ensembl Protein ID

ENSOARP00000002052.1

UniProt Accession

W5NV57; W5NV57_SHEEP

Genbank Protein ID

ENSOARP00000002052

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01093185

Gene Name

ARHGAP26

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000001949.1	ENSOART00000002101.1	ENSOARP00000002052.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.20e-12	47.8	762	815

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           k ++ly  +a++d eL++++G v + + + +q+ gWl+g  +l+gk Gl+Pen+ve 
   Q: 762  KAKALYACKAEHDSELSFTAGTVFDNV-HPSQEPGWLEG--TLNGKTGLIPENYVEY 815
           679************************.***********..8*************85 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MGLPALEFSD CCLDSPHFRE TLKSHEAELD KTNKFIKELI KDGKSLISAL KNLSSAKRKF 60
ADSLNEFKFQ CIGDAETDDE MCIARSLQEF ATVLRNLEDE RIRMIENASE VLITPLEKFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGCTGC CCGCGCTCGA ATTCAGTGAC TGCTGCCTCG ACAGCCCTCA CTTCCGAGAG 60
ACGCTGAAGT CGCACGAAGC GGAGCTGGAC AAGACCAACA AATTCATCAA GGAGCTCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0343--GTPase activation
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR030061--RHG26
IPR008936--Rho_GTPase_activation_prot
IPR000198--RhoGAP_dom
IPR001452--SH3_domain

PROSITE

PS50003--PH_DOMAIN
PS50238--RHOGAP
PS50002--SH3

Pfam

PF00169--PH
PF00620--RhoGAP
PF14604--SH3_9

SMART

SM00233--PH
SM00324--RhoGAP
SM00326--SH3

Gene Ontology

GO:0005096--F:GTPase activator activity
GO:0005543--F:phospholipid binding
GO:0030036--P:actin cytoskeleton organization
GO:0051056--P:regulation of small GTPase mediated signal transduction
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001613	Ailuropoda melanoleuca	97.67	0.00e+00	1387.00
IUUC-Apl-003321	Anas platyrhynchos	85.73	0.00e+00	1138.00
IUUC-Aca-004570	Anolis carolinensis	89.73	0.00e+00	1164.00
IUUC-Ame-011422	Astyanax mexicanus	79.46	0.00e+00	855.00
IUUC-Bta-013262	Bos taurus	99.01	0.00e+00	1120.00
IUUC-Cel-018542	Caenorhabditis elegans	43.62	4.00e-131	462.00
IUUC-Cja-019208	Callithrix jacchus	98.87	0.00e+00	1196.00
IUUC-Cfa-020928	Canis familiaris	98.18	0.00e+00	1212.00
IUUC-Cpo-021338	Cavia porcellus	96.20	0.00e+00	1410.00
IUUC-Csa-023570	Chlorocebus sabaeus	98.54	0.00e+00	1193.00
IUUC-Dno-029143	Dasypus novemcinctus	97.06	0.00e+00	1409.00
IUUC-Dor-030697	Dipodomys ordii	95.59	0.00e+00	1392.00
IUUC-Dme-032147	Drosophila melanogaster	45.61	6.00e-138	485.00
IUUC-Ete-032645	Echinops telfairi	88.77	0.00e+00	1047.00
IUUC-Eca-033791	Equus caballus	97.79	0.00e+00	1419.00
IUUC-Eeu-035202	Erinaceus europaeus	83.37	2.00e-179	622.00
IUUC-Fca-036131	Felis catus	97.75	0.00e+00	1389.00
IUUC-Fal-037129	Ficedula albicollis	91.68	0.00e+00	1133.00
IUUC-Gga-041023	Gallus gallus	91.83	0.00e+00	1173.00
IUUC-Ggo-044863	Gorilla gorilla	96.45	0.00e+00	1407.00
IUUC-Hsa-046471	Homo sapiens	96.08	0.00e+00	1395.00
IUUC-Itr-049060	Ictidomys tridecemlineatus	95.71	0.00e+00	1429.00
IUUC-Lch-050300	Latimeria chalumnae	75.54	0.00e+00	1031.00
IUUC-Loc-052782	Lepisosteus oculatus	80.91	0.00e+00	1055.00
IUUC-Laf-053585	Loxodonta africana	96.20	0.00e+00	1377.00
IUUC-Mcc-055458	Macaca mulatta	98.71	0.00e+00	1197.00
IUUC-Meu-056107	Macropus eugenii	77.33	0.00e+00	1082.00
IUUC-Mga-059914	Meleagris gallopavo	89.11	0.00e+00	1041.00
IUUC-Mmr-060728	Microcebus murinus	95.55	0.00e+00	1295.00
IUUC-Mdo-062387	Monodelphis domestica	89.96	0.00e+00	1333.00
IUUC-Mmu-063756	Mus musculus	97.08	0.00e+00	1204.00
IUUC-Nle-069043	Nomascus leucogenys	92.93	0.00e+00	874.00
IUUC-Opr-071168	Ochotona princeps	82.97	0.00e+00	1185.00
IUUC-Ont-072338	Oreochromis niloticus	76.87	0.00e+00	900.00
IUUC-Oan-073441	Ornithorhynchus anatinus	92.11	0.00e+00	974.00
IUUC-Ocu-073915	Oryctolagus cuniculus	93.87	0.00e+00	1384.00
IUUC-Ola-086319	Oryzias latipes	76.96	0.00e+00	937.00
IUUC-Ptr-091027	Pan troglodytes	96.32	0.00e+00	1400.00
IUUC-Pan-092791	Papio anubis	98.70	0.00e+00	1195.00
IUUC-Psi-093144	Pelodiscus sinensis	91.53	0.00e+00	1214.00
IUUC-Pab-097783	Pongo abelii	96.20	0.00e+00	1403.00
IUUC-Pva-102980	Pteropus vampyrus	96.69	0.00e+00	1456.00
IUUC-Rno-105142	Rattus norvegicus	95.90	0.00e+00	1226.00
IUUC-Sha-107213	Sarcophilus harrisii	93.46	0.00e+00	1120.00
IUUC-Tru-117767	Takifugu rubripes	77.02	0.00e+00	973.00
IUUC-Tsy-119150	Tarsius syrichta	93.50	0.00e+00	1366.00
IUUC-Tni-119893	Tetraodon nigroviridis	77.57	0.00e+00	692.00
IUUC-Ttr-129028	Tursiops truncatus	88.37	0.00e+00	1134.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence