iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066524

Ensembl Protein ID

ENSMPUP00000013477.1

UniProt Accession

M3YQ69; M3YQ69_MUSPF

Genbank Protein ID

ENSMPUP00000013477

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01012852

Gene Name

KLHL7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000013580.1	ENSMPUT00000013693.1	ENSMPUP00000013477.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.20e-18	67.2	61	127
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	4.00e-14	51.5	161	191

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +Dvil v++++++ah++vLaa+S++F+ +f++++ esk + +ve+kd +p+  ++l++F Yt +++ n
   Q: 61   CDVILMVQERKIPAHRVVLAAASHFFNLMFTTNMLESK-SFEVELKDAEPDIIEQLVEFAYTARISVN 127
           9*************************************.*************************9876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
           +Nclgi  +A+++dcp+Lk  a+dfi++hF+
   Q: 161  SNCLGISVLAECLDCPELKATADDFIHQHFT 191
           8*****************************7 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MAASGVEKSS KKKTEKKLAA REEAKLLAGF MGVMNNMRKQ VSKHSWKISH YWAVLSQKTL 60
CDVILMVQER KIPAHRVVLA AASHFFNLMF TTNMLESKSF EVELKDAEPD IIEQLVEFAY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTACCATTTC AAATAATCTT GTATTATTAG CATACACTAG AAAGAATAGA TTATTATCGT 60
TTAAAAAAAA AAAAAAGCCT TTTCATGAGT CCTGCGACTG AGTTTCGCGT CACGGTAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030599--KLHL7
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001981	Ailuropoda melanoleuca	97.18	0.00e+00	1167.00
IUUC-Apl-003183	Anas platyrhynchos	95.82	0.00e+00	1148.00
IUUC-Aca-004273	Anolis carolinensis	95.11	0.00e+00	1147.00
IUUC-Ame-011343	Astyanax mexicanus	81.10	0.00e+00	959.00
IUUC-Bta-012785	Bos taurus	97.01	0.00e+00	1164.00
IUUC-Cja-019038	Callithrix jacchus	96.85	0.00e+00	1187.00
IUUC-Cfa-020774	Canis familiaris	100.00	0.00e+00	1148.00
IUUC-Cpo-021716	Cavia porcellus	96.68	0.00e+00	1158.00
IUUC-Csa-023029	Chlorocebus sabaeus	97.01	0.00e+00	1165.00
IUUC-Cho-024947	Choloepus hoffmanni	74.63	0.00e+00	838.00
IUUC-Dre-028014	Danio rerio	80.91	0.00e+00	868.00
IUUC-Dno-029946	Dasypus novemcinctus	96.68	0.00e+00	1163.00
IUUC-Dor-030916	Dipodomys ordii	79.21	3.00e-173	601.00
IUUC-Dse-031294	Dothistroma septosporum	32.95	3.00e-06	44.30
IUUC-Ete-032454	Echinops telfairi	93.69	0.00e+00	637.00
IUUC-Eca-034041	Equus caballus	96.85	0.00e+00	1165.00
IUUC-Eeu-034627	Erinaceus europaeus	95.48	0.00e+00	959.00
IUUC-Fca-035854	Felis catus	97.18	0.00e+00	1167.00
IUUC-Fal-036883	Ficedula albicollis	95.81	0.00e+00	1149.00
IUUC-Gmo-038902	Gadus morhua	78.93	0.00e+00	898.00
IUUC-Gga-040866	Gallus gallus	95.83	0.00e+00	1155.00
IUUC-Gac-041428	Gasterosteus aculeatus	76.00	0.00e+00	930.00
IUUC-Ggo-044846	Gorilla gorilla	94.88	0.00e+00	1080.00
IUUC-Hsa-047034	Homo sapiens	97.01	0.00e+00	1165.00
IUUC-Itr-048807	Ictidomys tridecemlineatus	93.59	7.00e-138	482.00
IUUC-Lch-049815	Latimeria chalumnae	87.20	0.00e+00	1045.00
IUUC-Loc-052232	Lepisosteus oculatus	85.09	0.00e+00	913.00
IUUC-Laf-053520	Loxodonta africana	96.85	0.00e+00	1162.00
IUUC-Mcc-055237	Macaca mulatta	96.85	0.00e+00	1165.00
IUUC-Meu-056095	Macropus eugenii	93.23	6.00e-176	609.00
IUUC-Mga-059927	Meleagris gallopavo	95.83	0.00e+00	1155.00
IUUC-Mmr-060974	Microcebus murinus	95.50	0.00e+00	1144.00
IUUC-Mdo-062729	Monodelphis domestica	92.65	0.00e+00	1120.00
IUUC-Mmu-063841	Mus musculus	95.02	0.00e+00	1146.00
IUUC-Mlu-067215	Myotis lucifugus	96.70	0.00e+00	1160.00
IUUC-Ncr-068856	Neurospora crassa	28.18	5.00e-05	42.00
IUUC-Nle-069341	Nomascus leucogenys	97.01	0.00e+00	1165.00
IUUC-Opr-070269	Ochotona princeps	96.52	0.00e+00	1161.00
IUUC-Ont-071551	Oreochromis niloticus	77.62	0.00e+00	934.00
IUUC-Oan-072718	Ornithorhynchus anatinus	99.45	0.00e+00	1145.00
IUUC-Ocu-074287	Oryctolagus cuniculus	97.01	0.00e+00	1165.00
IUUC-Ola-086718	Oryzias latipes	76.25	0.00e+00	946.00
IUUC-Oga-088757	Otolemur garnettii	96.52	0.00e+00	1162.00
IUUC-Oar-090309	Ovis aries	97.01	0.00e+00	1164.00
IUUC-Ptr-090509	Pan troglodytes	97.01	0.00e+00	1165.00
IUUC-Pan-092929	Papio anubis	97.01	0.00e+00	1165.00
IUUC-Psi-092941	Pelodiscus sinensis	95.99	0.00e+00	1154.00
IUUC-Pfo-097421	Poecilia formosa	77.22	0.00e+00	921.00
IUUC-Pab-097792	Pongo abelii	97.01	0.00e+00	1165.00
IUUC-Pca-101033	Procavia capensis	87.03	0.00e+00	846.00
IUUC-Pva-102364	Pteropus vampyrus	87.06	0.00e+00	1020.00
IUUC-Rno-105596	Rattus norvegicus	95.19	0.00e+00	1147.00
IUUC-Sha-106815	Sarcophilus harrisii	99.44	0.00e+00	1129.00
IUUC-Smo-109320	Selaginella moellendorffii	25.26	6.00e-16	79.70
IUUC-Sar-113305	Sorex araneus	96.52	0.00e+00	1162.00
IUUC-Ssc-115871	Sus scrofa	95.86	3.00e-168	583.00
IUUC-Tgu-116940	Taeniopygia guttata	95.46	0.00e+00	1146.00
IUUC-Tru-118682	Takifugu rubripes	76.55	0.00e+00	949.00
IUUC-Tsy-118787	Tarsius syrichta	98.95	0.00e+00	801.00
IUUC-Tni-120224	Tetraodon nigroviridis	77.11	0.00e+00	951.00
IUUC-Tbe-127633	Tupaia belangeri	57.05	5.00e-88	317.00
IUUC-Ttr-128500	Tursiops truncatus	95.65	0.00e+00	1148.00
IUUC-Vpa-130512	Vicugna pacos	97.80	0.00e+00	1120.00
IUUC-Xtr-131983	Xenopus tropicalis	94.25	0.00e+00	1137.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence