iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088276

Ensembl Protein ID

ENSOGAP00000008960.2

UniProt Accession

H0X1S4; H0X1S4_OTOGA

Genbank Protein ID

ENSOGAP00000008960

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03008680

Gene Name

SH3RF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000010029.2	ENSOGAT00000010032.2	ENSOGAP00000008960.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.40e-08	33.3	12	53
UBD/SH3	9.90e-14	51.1	131	180

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cle ++   +vlpC+H+f++ Clqk+     ++ ke rCP Cr
   Q: 12   CPVCLEKLDVTAKVLPCQHTFCKPCLQKV----FKAHKELRCPECR 53
           ********88899****************....99**********8 PP

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           ++l +y +q+ ++L ++kGdv+ +    + de+W +g  e +g +G+fP+  ve
   Q: 131  KALCNYRGQSPGDLRFNKGDVIVL--RRQLDENWYQG--EVNGTSGIFPASSVE 180
           78999****************988..69*********..9*********97766 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MDDLTLLDFL ECPVCLEKLD VTAKVLPCQH TFCKPCLQKV FKAHKELRCP ECRTLVFCSI 60
ESLPANLLLV RLLDGVRAGK SPGRGGSFRR PGVLTLPDGR KGRANPRGLQ ASSFRLVPNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGATT TGACATTACT TGATTTTCTG GAGTGCCCTG TGTGCTTGGA AAAGCTCGAT 60
GTCACAGCCA AAGTCCTCCC CTGCCAGCAT ACCTTCTGCA AACCCTGCCT GCAGAAGGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011511--SH3_2
IPR001452--SH3_domain
IPR028511--SH3RF2
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00018--SH3_1
PF07653--SH3_2
PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008270--F:zinc ion binding
GO:0010923--P:negative regulation of phosphatase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001594	Ailuropoda melanoleuca	78.35	0.00e+00	982.00
IUUC-Apl-003443	Anas platyrhynchos	53.19	2.00e-155	542.00
IUUC-Aca-004632	Anolis carolinensis	50.78	4.00e-152	531.00
IUUC-Bta-013400	Bos taurus	80.76	0.00e+00	984.00
IUUC-Cja-019686	Callithrix jacchus	70.67	0.00e+00	875.00
IUUC-Cfa-020893	Canis familiaris	79.95	0.00e+00	993.00
IUUC-Cpo-021638	Cavia porcellus	74.86	0.00e+00	939.00
IUUC-Csa-023846	Chlorocebus sabaeus	81.76	0.00e+00	1041.00
IUUC-Cho-024609	Choloepus hoffmanni	83.33	2.00e-173	602.00
IUUC-Cin-025274	Ciona intestinalis	48.48	7.00e-66	243.00
IUUC-Csv-026136	Ciona savignyi	43.93	7.00e-65	241.00
IUUC-Dno-028940	Dasypus novemcinctus	78.67	0.00e+00	1004.00
IUUC-Dor-030491	Dipodomys ordii	85.08	1.00e-111	397.00
IUUC-Dme-032207	Drosophila melanogaster	39.71	8.00e-56	212.00
IUUC-Ete-032513	Echinops telfairi	78.08	0.00e+00	982.00
IUUC-Eca-034241	Equus caballus	81.56	0.00e+00	1054.00
IUUC-Eeu-034636	Erinaceus europaeus	74.59	0.00e+00	857.00
IUUC-Fca-035862	Felis catus	77.79	0.00e+00	999.00
IUUC-Gga-040748	Gallus gallus	53.00	6.00e-153	534.00
IUUC-Ggo-045267	Gorilla gorilla	81.48	0.00e+00	1042.00
IUUC-Hsa-045761	Homo sapiens	81.21	0.00e+00	1033.00
IUUC-Itr-048226	Ictidomys tridecemlineatus	76.50	0.00e+00	957.00
IUUC-Lch-050498	Latimeria chalumnae	42.70	1.00e-109	390.00
IUUC-Laf-054061	Loxodonta africana	75.61	0.00e+00	796.00
IUUC-Mcc-054746	Macaca mulatta	81.09	0.00e+00	996.00
IUUC-Meu-056390	Macropus eugenii	52.97	2.00e-72	266.00
IUUC-Mga-059398	Meleagris gallopavo	64.39	4.00e-92	330.00
IUUC-Mmr-061390	Microcebus murinus	79.44	0.00e+00	828.00
IUUC-Mdo-062951	Monodelphis domestica	65.45	0.00e+00	877.00
IUUC-Mmu-063840	Mus musculus	73.23	0.00e+00	936.00
IUUC-Mpu-065840	Mustela putorius furo	78.85	0.00e+00	1027.00
IUUC-Mlu-067378	Myotis lucifugus	78.59	0.00e+00	965.00
IUUC-Nle-069535	Nomascus leucogenys	80.11	0.00e+00	966.00
IUUC-Opr-070739	Ochotona princeps	76.09	0.00e+00	949.00
IUUC-Oan-073468	Ornithorhynchus anatinus	61.82	0.00e+00	729.00
IUUC-Ocu-074343	Oryctolagus cuniculus	77.64	0.00e+00	942.00
IUUC-Oar-090315	Ovis aries	79.10	0.00e+00	976.00
IUUC-Ptr-091119	Pan troglodytes	81.07	0.00e+00	1031.00
IUUC-Pan-092158	Papio anubis	80.92	0.00e+00	749.00
IUUC-Psi-092959	Pelodiscus sinensis	57.47	0.00e+00	684.00
IUUC-Pab-097675	Pongo abelii	81.62	0.00e+00	1024.00
IUUC-Pca-101021	Procavia capensis	71.76	0.00e+00	867.00
IUUC-Pva-102619	Pteropus vampyrus	79.23	0.00e+00	976.00
IUUC-Rno-105918	Rattus norvegicus	72.96	0.00e+00	938.00
IUUC-Sha-107391	Sarcophilus harrisii	62.14	0.00e+00	799.00
IUUC-Sar-113148	Sorex araneus	79.30	2.00e-164	572.00
IUUC-Ssc-116219	Sus scrofa	70.03	9.00e-102	363.00
IUUC-Tgu-116584	Taeniopygia guttata	53.30	2.00e-102	365.00
IUUC-Tsy-118968	Tarsius syrichta	71.05	0.00e+00	744.00
IUUC-Tbe-128007	Tupaia belangeri	79.27	0.00e+00	722.00
IUUC-Ttr-128499	Tursiops truncatus	77.19	0.00e+00	995.00
IUUC-Vpa-130075	Vicugna pacos	64.88	1.00e-88	320.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence