iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-118398

Ensembl Protein ID

ENSTRUP00000012504.1

UniProt Accession

H2SJC1; H2SJC1_TAKRU

Protein Name

Uncharacterized protein

Gene Name

vav2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000005204.1	ENSTRUT00000012563.1	ENSTRUP00000012503.1
ENSTRUG00000005204.1	ENSTRUT00000012564.1	ENSTRUP00000012504.1
ENSTRUG00000005204.1	ENSTRUT00000012565.1	ENSTRUP00000012505.1
ENSTRUG00000005204.1	ENSTRUT00000012566.1	ENSTRUP00000012506.1
ENSTRUG00000005204.1	ENSTRUT00000012567.1	ENSTRUP00000012507.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.50e-18	65.9	570	621

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            + y++ a +  eL+l++Gd+v++ +k   d+gW+kg  e++g+ G fP+ +v 
   Q: 570  VARYNFAARDMRELSLREGDMVRIYSKIGGDQGWWKG--EANGRIGWFPSTYVD 621
           578**********************************..9************96 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

QVHFALLRAI DLNMVSGGSG LGKIFLDFKE RLLIYGQYCS HMENAQKTLD ELIATREDIK 60
IKVEECTMKV QEGKFKLQDL LVVPMQRVLK YHLLLKELLS HSNDRPERQQ LKEALEAMQD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAGTCCACT TTGCCCTCCT GCGAGCAATC GATCTCAACA TGGTCAGTGG AGGAAGCGGA 60
TTGGGGAAGA TCTTCCTTGA CTTCAAAGAG AGGTTGGTGC CAAGGCTCAC ATTGCTTTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc

Interpro

IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF00169--PH
PF00621--RhoGEF
PF00017--SH2
PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00109--C1
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001437	Ailuropoda melanoleuca	79.27	0.00e+00	959.00
IUUC-Apl-003262	Anas platyrhynchos	80.38	0.00e+00	975.00
IUUC-Aca-004628	Anolis carolinensis	56.74	0.00e+00	629.00
IUUC-Ame-011608	Astyanax mexicanus	85.02	0.00e+00	1102.00
IUUC-Bta-013147	Bos taurus	78.03	0.00e+00	979.00
IUUC-Bra-017317	Brassica rapa	33.33	2.60e-01	30.40
IUUC-Cja-018877	Callithrix jacchus	78.45	0.00e+00	964.00
IUUC-Cfa-020315	Canis familiaris	76.08	0.00e+00	944.00
IUUC-Cpo-021543	Cavia porcellus	77.42	0.00e+00	949.00
IUUC-Csa-024204	Chlorocebus sabaeus	76.46	0.00e+00	961.00
IUUC-Dre-028308	Danio rerio	90.22	0.00e+00	1163.00
IUUC-Dno-029584	Dasypus novemcinctus	73.08	0.00e+00	880.00
IUUC-Dor-031014	Dipodomys ordii	64.99	0.00e+00	742.00
IUUC-Eca-033448	Equus caballus	75.00	0.00e+00	923.00
IUUC-Fca-035460	Felis catus	76.71	0.00e+00	940.00
IUUC-Fal-036684	Ficedula albicollis	79.91	0.00e+00	974.00
IUUC-Gmo-038816	Gadus morhua	84.90	0.00e+00	1059.00
IUUC-Gga-040999	Gallus gallus	76.24	0.00e+00	937.00
IUUC-Gac-041353	Gasterosteus aculeatus	87.60	0.00e+00	1101.00
IUUC-Ggo-044558	Gorilla gorilla	78.96	0.00e+00	972.00
IUUC-Hsa-046208	Homo sapiens	78.64	0.00e+00	969.00
IUUC-Itr-047931	Ictidomys tridecemlineatus	77.07	0.00e+00	936.00
IUUC-Loc-052827	Lepisosteus oculatus	86.75	0.00e+00	1139.00
IUUC-Laf-054009	Loxodonta africana	73.52	0.00e+00	909.00
IUUC-Mcc-055054	Macaca mulatta	78.64	0.00e+00	969.00
IUUC-Meu-056269	Macropus eugenii	74.00	0.00e+00	650.00
IUUC-Mga-060106	Meleagris gallopavo	80.22	0.00e+00	974.00
IUUC-Mmr-061118	Microcebus murinus	77.83	0.00e+00	952.00
IUUC-Mdo-062380	Monodelphis domestica	75.35	0.00e+00	936.00
IUUC-Mmu-063135	Mus musculus	79.11	0.00e+00	983.00
IUUC-Mpu-066135	Mustela putorius furo	75.28	0.00e+00	942.00
IUUC-Nle-069465	Nomascus leucogenys	74.37	0.00e+00	881.00
IUUC-Ont-071945	Oreochromis niloticus	91.00	0.00e+00	1146.00
IUUC-Oan-073384	Ornithorhynchus anatinus	77.97	0.00e+00	947.00
IUUC-Ola-087499	Oryzias latipes	87.38	0.00e+00	1091.00
IUUC-Oga-088444	Otolemur garnettii	75.12	0.00e+00	928.00
IUUC-Oar-089576	Ovis aries	76.59	0.00e+00	941.00
IUUC-Ptr-090507	Pan troglodytes	79.27	0.00e+00	970.00
IUUC-Pan-092325	Papio anubis	75.76	0.00e+00	927.00
IUUC-Psi-094021	Pelodiscus sinensis	75.24	0.00e+00	918.00
IUUC-Pfo-096732	Poecilia formosa	92.59	0.00e+00	1181.00
IUUC-Pab-098426	Pongo abelii	62.88	0.00e+00	717.00
IUUC-Pca-100295	Procavia capensis	77.85	0.00e+00	982.00
IUUC-Rno-105332	Rattus norvegicus	78.63	0.00e+00	954.00
IUUC-Sha-106529	Sarcophilus harrisii	79.65	0.00e+00	981.00
IUUC-Ssc-116176	Sus scrofa	78.76	0.00e+00	967.00
IUUC-Tgu-116917	Taeniopygia guttata	79.90	0.00e+00	975.00
IUUC-Tni-120819	Tetraodon nigroviridis	95.37	0.00e+00	1209.00
IUUC-Xtr-132747	Xenopus tropicalis	72.36	0.00e+00	897.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence