iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ani-009495

Ensembl Protein ID

CADANIAP00002420

UniProt Accession

Q5BGN5; C8VUA1; NPL4_EMENI

Genbank Protein ID

EAA65701.1; CBF89782.1

Protein Name

Nuclear protein localization protein 4

Genbank Nucleotide ID

AACD01000006; BN001308

Gene Name

ANIA_00295; npl4; AN0295

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADANIAG00002420	CADANIAT00002420	CADANIAP00002420

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/NZF	39.49	1.00e-91	335.00	IUUC-Mmu-063916
UBD/ZnF/Other	43.18	6.00e-144	506.00	IUUC-Sce-106145

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Aspergillus nidulans

Functional Description
(View)

Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity).

Protein Sequence
(Fasta)

MTSRTIILRF ESRNGQFRLN VSPQDMFPSL ETKILEHLPP DTEPSSIKLS NKPIGAAGDE 60
RFLNTLDGVS FEQVGLRSGH GDKLYIGYQS KQDLQDGASN GTAAGSSARR LNGAPINQEI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTCCTGCA TATGTCCTCT ACTTCTCAGA AATTACTCAA TCTATGGAAT GAGCATAAGT 60
GAGATAGACA TAATTCTCAT CCTCTAAACA CCTCTACAGC ACCCTACCCA TACCCGTCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0256--Endoplasmic reticulum
KW-0472--Membrane
KW-0509--mRNA transport
KW-0539--Nucleus
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0811--Translocation
KW-0813--Transport

Interpro

IPR016563--Npl4
IPR007717--NPL4_C
IPR007716--NPL4_Zn-bd_put
IPR029071--Ubiquitin-rel_dom

Pfam

PF05021--NPL4
PF05020--zf-NPL4

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0031965--C:nuclear membrane
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0043130--F:ubiquitin binding
GO:0031625--F:ubiquitin protein ligase binding
GO:0051028--P:mRNA transport
GO:0015031--P:protein transport
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ani:AN0295.2

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000460	Aegilops tauschii	25.71	5.00e-08	50.40
IUUC-Aml-002268	Ailuropoda melanoleuca	39.62	8.00e-94	336.00
IUUC-Atr-002939	Amborella trichopoda	25.85	2.00e-07	48.90
IUUC-Apl-003496	Anas platyrhynchos	37.73	3.00e-97	347.00
IUUC-Aca-005230	Anolis carolinensis	39.70	2.00e-94	338.00
IUUC-Aly-005413	Arabidopsis lyrata	25.59	2.00e-11	61.60
IUUC-Ath-006993	Arabidopsis thaliana	26.93	9.00e-13	66.20
IUUC-Ago-007954	Ashbya gossypii	40.23	7.00e-121	425.00
IUUC-Acl-008208	Aspergillus clavatus	76.74	0.00e+00	1009.00
IUUC-Afl-008574	Aspergillus flavus	80.83	0.00e+00	1004.00
IUUC-Afu-008825	Aspergillus fumigatus	77.98	0.00e+00	1035.00
IUUC-Ang-009762	Aspergillus niger	76.16	0.00e+00	1017.00
IUUC-Aor-010199	Aspergillus oryzae	80.00	0.00e+00	1042.00
IUUC-Ate-010592	Aspergillus terreus	80.95	0.00e+00	963.00
IUUC-Ame-011438	Astyanax mexicanus	44.97	2.00e-32	129.00
IUUC-Bgr-012124	Blumeria graminis	58.02	0.00e+00	740.00
IUUC-Bta-013312	Bos taurus	33.93	1.00e-94	338.00
IUUC-Bci-013648	Botrytis cinerea	60.26	0.00e+00	759.00
IUUC-Bdi-014326	Brachypodium distachyon	25.00	8.00e-08	49.70
IUUC-Bol-016294	Brassica oleracea	26.61	1.00e-13	68.90
IUUC-Bra-017023	Brassica rapa	26.61	3.00e-13	67.80
IUUC-Cel-018206	Caenorhabditis elegans	35.31	4.00e-81	293.00
IUUC-Cja-018869	Callithrix jacchus	39.07	3.00e-93	333.00
IUUC-Cfa-020757	Canis familiaris	39.49	1.00e-93	335.00
IUUC-Cpo-022390	Cavia porcellus	38.41	8.00e-94	335.00
IUUC-Csa-023366	Chlorocebus sabaeus	33.93	7.00e-94	336.00
IUUC-Cho-024455	Choloepus hoffmanni	36.04	2.00e-65	241.00
IUUC-Cin-025638	Ciona intestinalis	33.11	1.00e-59	222.00
IUUC-Csv-026310	Ciona savignyi	31.60	6.00e-62	229.00
IUUC-Cgl-026685	Colletotrichum gloeosporioides	57.97	0.00e+00	742.00
IUUC-Cne-026794	Cryptococcus neoformans	38.84	8.00e-123	432.00
IUUC-Cme-027248	Cyanidioschyzon merolae	26.92	1.00e-08	52.80
IUUC-Dre-027689	Danio rerio	34.48	7.00e-95	339.00
IUUC-Dno-030004	Dasypus novemcinctus	34.26	3.00e-94	337.00
IUUC-Dor-030585	Dipodomys ordii	39.65	6.00e-91	326.00
IUUC-Dse-031202	Dothistroma septosporum	53.95	0.00e+00	667.00
IUUC-Dme-032092	Drosophila melanogaster	34.87	4.00e-96	343.00
IUUC-Ete-033009	Echinops telfairi	38.12	5.00e-25	107.00
IUUC-Eca-034001	Equus caballus	39.49	1.00e-93	335.00
IUUC-Eeu-034485	Erinaceus europaeus	29.89	5.00e-58	216.00
IUUC-Fca-036128	Felis catus	39.49	1.00e-93	335.00
IUUC-Fal-037523	Ficedula albicollis	35.14	6.00e-97	346.00
IUUC-Fox-037802	Fusarium oxysporum	57.73	0.00e+00	740.00
IUUC-Fso-038152	Fusarium solani	58.22	0.00e+00	744.00
IUUC-Gmo-038486	Gadus morhua	38.51	1.00e-90	325.00
IUUC-Ggr-039916	Gaeumannomyces graminis	59.42	0.00e+00	755.00
IUUC-Gga-041208	Gallus gallus	35.24	1.00e-97	348.00
IUUC-Gac-042304	Gasterosteus aculeatus	38.30	1.00e-86	312.00
IUUC-Gma-044007	Glycine max	37.78	7.00e-07	46.60
IUUC-Ggo-045236	Gorilla gorilla	38.22	2.00e-87	314.00
IUUC-Hsa-046334	Homo sapiens	39.28	1.00e-93	335.00
IUUC-Hvu-047323	Hordeum vulgare	23.11	1.00e-02	31.60
IUUC-Itr-047878	Ictidomys tridecemlineatus	46.38	1.00e-69	254.00
IUUC-Lch-050302	Latimeria chalumnae	33.17	1.00e-86	312.00
IUUC-Lpe-051362	Leersia perrieri	24.84	2.00e-09	55.50
IUUC-Loc-052548	Lepisosteus oculatus	39.02	2.00e-92	331.00
IUUC-Lma-053092	Leptosphaeria maculans	58.32	0.00e+00	773.00
IUUC-Laf-053911	Loxodonta africana	34.26	3.00e-94	337.00
IUUC-Mcc-055830	Macaca mulatta	39.28	1.00e-93	335.00
IUUC-Meu-056460	Macropus eugenii	36.51	4.00e-13	67.40
IUUC-Mor-057189	Magnaporthe oryzae	56.33	0.00e+00	757.00
IUUC-Mpo-057366	Magnaporthe poae	58.36	0.00e+00	733.00
IUUC-Mtr-057834	Medicago truncatula	35.56	1.00e-05	42.40
IUUC-Mla-059190	Melampsora laricipopulina	41.95	3.00e-139	487.00
IUUC-Mga-060036	Meleagris gallopavo	34.98	3.00e-96	343.00
IUUC-Mvi-060275	Microbotryum violaceum	40.06	2.00e-129	454.00
IUUC-Mmr-061300	Microcebus murinus	39.49	2.00e-93	335.00
IUUC-Mdo-062911	Monodelphis domestica	35.46	9.00e-93	332.00
IUUC-Mmu-063916	Mus musculus	39.49	6.00e-94	336.00
IUUC-Mac-065601	Musa acuminata	32.53	6.00e-04	37.00
IUUC-Mpu-065912	Mustela putorius furo	39.41	9.00e-94	335.00
IUUC-Mlu-067965	Myotis lucifugus	39.62	3.00e-94	337.00
IUUC-Nfi-068465	Neosartorya fischeri	78.13	0.00e+00	1037.00
IUUC-Ncr-068936	Neurospora crassa	58.76	0.00e+00	732.00
IUUC-Nle-069570	Nomascus leucogenys	33.93	3.00e-94	337.00
IUUC-Opr-071097	Ochotona princeps	38.13	7.00e-85	306.00
IUUC-Ont-071430	Oreochromis niloticus	40.09	2.00e-96	344.00
IUUC-Oan-073709	Ornithorhynchus anatinus	31.93	1.00e-54	205.00
IUUC-Ocu-074875	Oryctolagus cuniculus	38.30	2.00e-84	305.00
IUUC-Oba-075214	Oryza barthii	24.84	3.00e-10	57.80
IUUC-Obr-076758	Oryza brachyantha	24.84	8.00e-09	52.80
IUUC-Ogl-077665	Oryza glaberrima	24.84	3.00e-10	57.80
IUUC-Ogu-078899	Oryza glumaepatula	24.84	3.00e-10	57.80
IUUC-Oin-079167	Oryza indica	24.84	3.00e-10	57.80
IUUC-Olo-080451	Oryza longistaminata	24.84	3.00e-10	57.00
IUUC-Ome-081836	Oryza meridionalis	24.76	3.00e-10	57.80
IUUC-Oni-083019	Oryza nivara	24.84	3.00e-10	57.80
IUUC-Opu-083122	Oryza punctata	25.73	9.00e-10	56.20
IUUC-Oru-084900	Oryza rufipogon	24.84	3.00e-10	57.80
IUUC-Osa-086054	Oryza sativa	24.84	3.00e-10	57.80
IUUC-Ola-087077	Oryzias latipes	40.14	1.00e-83	302.00
IUUC-Oga-088049	Otolemur garnettii	36.83	3.00e-81	294.00
IUUC-Oar-089678	Ovis aries	39.28	2.00e-93	335.00
IUUC-Ptr-091380	Pan troglodytes	33.44	6.00e-94	336.00
IUUC-Pan-092821	Papio anubis	38.43	1.00e-89	322.00
IUUC-Psi-093074	Pelodiscus sinensis	39.61	2.00e-94	337.00
IUUC-Pma-094102	Petromyzon marinus	34.19	6.00e-90	323.00
IUUC-Pno-094987	Phaeosphaeria nodorum	60.56	0.00e+00	772.00
IUUC-Ppa-095368	Physcomitrella patens	25.25	2.00e-08	51.60
IUUC-Pfo-097245	Poecilia formosa	40.30	7.00e-97	346.00
IUUC-Pab-098763	Pongo abelii	39.28	1.00e-93	335.00
IUUC-Pop-099355	Populus trichocarpa	31.93	2.00e-05	42.00
IUUC-Ppe-101990	Prunus persica	24.38	7.00e-08	49.70
IUUC-Pva-102308	Pteropus vampyrus	34.66	9.00e-75	272.00
IUUC-Pgr-103553	Puccinia graminis	43.08	1.00e-137	481.00
IUUC-Pte-104100	Pyrenophora teres	57.25	0.00e+00	769.00
IUUC-Pyt-104482	Pyrenophora triticirepentis	56.50	0.00e+00	754.00
IUUC-Rno-105582	Rattus norvegicus	39.49	7.00e-94	336.00
IUUC-Sce-106145	Saccharomyces cerevisiae	43.97	6.00e-141	492.00
IUUC-Sha-106647	Sarcophilus harrisii	38.95	6.00e-94	336.00
IUUC-Sja-107972	Schizosaccharomyces japonicus	44.00	3.00e-142	496.00
IUUC-Spo-108281	Schizosaccharomyces pombe	44.61	1.00e-140	491.00
IUUC-Ssl-108617	Sclerotinia sclerotiorum	60.16	0.00e+00	757.00
IUUC-Smo-108933	Selaginella moellendorffii	26.86	5.00e-10	57.00
IUUC-Sit-110083	Setaria italica	26.06	3.00e-10	58.20
IUUC-Sly-111645	Solanum lycopersicum	34.48	1.00e-06	45.80
IUUC-Stu-112422	Solanum tuberosum	34.48	1.00e-06	45.80
IUUC-Sbi-113987	Sorghum bicolor	25.73	5.00e-09	53.50
IUUC-Sre-115095	Sporisorium reilianum	43.97	2.00e-142	498.00
IUUC-Ssc-116141	Sus scrofa	39.28	5.00e-93	333.00
IUUC-Tgu-117492	Taeniopygia guttata	35.01	1.00e-81	295.00
IUUC-Tru-118463	Takifugu rubripes	39.66	5.00e-94	336.00
IUUC-Tsy-118993	Tarsius syrichta	34.64	1.00e-71	262.00
IUUC-Tni-119896	Tetraodon nigroviridis	39.66	8.00e-94	335.00
IUUC-Tca-121169	Theobroma cacao	25.71	3.00e-09	54.70
IUUC-Tre-122046	Trichoderma reesei	58.54	0.00e+00	730.00
IUUC-Tvi-122415	Trichoderma virens	56.86	0.00e+00	707.00
IUUC-Tae-123514	Triticum aestivum	24.76	4.00e-08	50.80
IUUC-Tme-127123	Tuber melanosporum	56.21	0.00e+00	719.00
IUUC-Tbe-127629	Tupaia belangeri	41.90	6.00e-45	173.00
IUUC-Ttr-128476	Tursiops truncatus	34.14	2.00e-69	255.00
IUUC-Uma-129492	Ustilago maydis	43.17	1.00e-142	498.00
IUUC-Vda-129702	Verticillium dahliae	54.99	0.00e+00	703.00
IUUC-Vvi-131090	Vitis vinifera	24.80	3.00e-06	44.70
IUUC-Xtr-131786	Xenopus tropicalis	38.77	6.00e-93	333.00
IUUC-Xma-133997	Xiphophorus maculatus	40.30	1.00e-96	345.00
IUUC-Yli-134537	Yarrowia lipolytica	43.87	9.00e-140	488.00
IUUC-Zma-134847	Zea mays	24.51	3.00e-09	54.70

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence