iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062106

UUCD1 version

UUC-MoD-00540

Ensembl Protein ID

ENSMODP00000020382.1

UniProt Accession

F7A674; F7A674_MONDO

Protein Name

Uncharacterized protein

Gene Name

RNF114

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000016308.2	ENSMODT00000020740.2	ENSMODP00000020382.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.30e-07	31.7	25	74
E3 activity/RING/RING	1.70e-06	28.6	30	69

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplte 52
           ++ f Cp+ le+ + Pv +p+G+++ + +++++l+ ++  c v+r+ l++
   Q: 25   LSRFTCPVCLEVYEKPVQVPCGHVFCALCLQQCLKPKKPVCGVCRSALSP 74
           578******************************************99965 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C++Cle +++ p+ +pCgHvf+a Cl q++      + k+  C +Cr
   Q: 30   CPVCLEVYEK-PVQVPCGHVFCALCLqQCL------KPKKPVCGVCR 69
           **********.999************5555......999*******8 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

ALGDDKMALD GGSGLVGATA AANPLSRFTC PVCLEVYEKP VQVPCGHVFC ALCLQQCLKP 60
KKPVCGVCRS ALSPGIRAMD LEKQIEATEA TCSGCKKNLV LSKMRNHVAS CSKYQSYLME 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCTGGGGG ACGACAAGAT GGCGCTGGAC GGCGGCTCTG GGCTGGTTGG GGCCACCGCA 60
GCAGCAAATC CCTTGTCGCG CTTCACGTGC CCGGTGTGTC TGGAGGTGTA CGAGAAGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008598--Di19_Zn_binding_dom
IPR034734--ZF_C2HC_RNF
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51803--ZF_C2HC_RNF
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF05605--zf-Di19
PF13445--zf-RING_UBOX

SMART

SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0005622--C:intracellular
GO:0005886--C:plasma membrane
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002315	Ailuropoda melanoleuca	79.09	3.00e-110	390.00
IUUC-Apl-004036	Anas platyrhynchos	77.35	2.00e-83	300.00
IUUC-Aca-004569	Anolis carolinensis	72.29	1.00e-98	352.00
IUUC-Bta-013345	Bos taurus	78.83	5.00e-111	393.00
IUUC-Cja-019919	Callithrix jacchus	79.55	9.00e-111	392.00
IUUC-Cfa-021164	Canis familiaris	75.88	9.00e-109	385.00
IUUC-Cpo-022051	Cavia porcellus	73.66	6.00e-104	369.00
IUUC-Csa-023956	Chlorocebus sabaeus	81.64	6.00e-107	379.00
IUUC-Dre-027499	Danio rerio	51.74	1.00e-64	239.00
IUUC-Dno-029437	Dasypus novemcinctus	80.18	7.00e-108	382.00
IUUC-Dor-030428	Dipodomys ordii	66.36	2.00e-87	315.00
IUUC-Ete-032855	Echinops telfairi	73.41	4.00e-76	277.00
IUUC-Eca-034236	Equus caballus	79.56	2.00e-90	324.00
IUUC-Eeu-034875	Erinaceus europaeus	82.35	3.00e-96	343.00
IUUC-Fca-036017	Felis catus	81.90	5.00e-108	383.00
IUUC-Fal-037133	Ficedula albicollis	77.90	1.00e-85	309.00
IUUC-Gga-040752	Gallus gallus	70.93	1.00e-95	342.00
IUUC-Ggo-044654	Gorilla gorilla	81.68	4.00e-66	243.00
IUUC-Hsa-046280	Homo sapiens	81.16	2.00e-106	377.00
IUUC-Itr-048594	Ictidomys tridecemlineatus	78.49	1.00e-90	325.00
IUUC-Lch-050028	Latimeria chalumnae	62.86	1.00e-78	285.00
IUUC-Loc-051797	Lepisosteus oculatus	52.42	3.00e-68	251.00
IUUC-Laf-054248	Loxodonta africana	79.56	3.00e-91	327.00
IUUC-Mcc-054724	Macaca mulatta	81.64	6.00e-107	379.00
IUUC-Meu-056464	Macropus eugenii	71.82	4.00e-62	230.00
IUUC-Mga-059403	Meleagris gallopavo	77.44	2.00e-62	230.00
IUUC-Mmr-061582	Microcebus murinus	81.22	1.00e-92	331.00
IUUC-Mmu-064176	Mus musculus	77.73	2.00e-98	351.00
IUUC-Mpu-066083	Mustela putorius furo	80.00	2.00e-111	394.00
IUUC-Mlu-067060	Myotis lucifugus	80.19	3.00e-104	370.00
IUUC-Nle-069353	Nomascus leucogenys	81.64	7.00e-97	346.00
IUUC-Opr-070916	Ochotona princeps	77.42	5.00e-105	373.00
IUUC-Ont-072284	Oreochromis niloticus	53.54	1.00e-71	262.00
IUUC-Oan-072858	Ornithorhynchus anatinus	76.24	7.00e-82	295.00
IUUC-Ocu-074471	Oryctolagus cuniculus	82.67	3.00e-105	374.00
IUUC-Ola-087569	Oryzias latipes	51.32	3.00e-72	264.00
IUUC-Oga-089164	Otolemur garnettii	80.66	6.00e-108	383.00
IUUC-Oar-089436	Ovis aries	79.28	1.00e-111	395.00
IUUC-Ptr-090945	Pan troglodytes	81.16	2.00e-106	377.00
IUUC-Pan-092765	Papio anubis	81.64	6.00e-107	379.00
IUUC-Psi-093593	Pelodiscus sinensis	76.76	2.00e-65	241.00
IUUC-Pfo-096157	Poecilia formosa	52.21	9.00e-71	259.00
IUUC-Pab-098509	Pongo abelii	81.25	4.00e-107	380.00
IUUC-Pca-100293	Procavia capensis	78.71	1.00e-96	345.00
IUUC-Pva-102556	Pteropus vampyrus	79.09	9.00e-109	385.00
IUUC-Rno-105634	Rattus norvegicus	77.73	1.00e-97	348.00
IUUC-Sha-107052	Sarcophilus harrisii	92.79	1.00e-105	375.00
IUUC-Sar-113680	Sorex araneus	80.11	4.00e-81	293.00
IUUC-Ssc-115451	Sus scrofa	80.11	1.00e-91	328.00
IUUC-Tgu-116515	Taeniopygia guttata	77.60	1.00e-84	305.00
IUUC-Tru-117712	Takifugu rubripes	51.54	3.00e-71	260.00
IUUC-Tsy-119419	Tarsius syrichta	79.56	7.00e-91	325.00
IUUC-Tni-119774	Tetraodon nigroviridis	52.42	3.00e-70	258.00
IUUC-Tbe-127924	Tupaia belangeri	76.71	6.00e-101	359.00
IUUC-Ttr-128721	Tursiops truncatus	80.00	1.00e-111	394.00
IUUC-Vpa-130175	Vicugna pacos	58.45	9.00e-72	262.00
IUUC-Xtr-131851	Xenopus tropicalis	56.93	8.00e-73	266.00
IUUC-Xma-133766	Xiphophorus maculatus	51.77	2.00e-70	258.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence