iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.10e-11	43.9	439	489

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            vlydy +++ de  l+kG++++v+  e  + gW+ g    +g  GlfP+ +v+
   Q: 439  VVLYDYAPAEGDEIALRKGEMIEVL-TEPDSLGWCTG--RVSGNVGLFPASYVQ 489
           69***********************.9999*******..8************96 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MSCLPCMAAD VLAPGFWEVG SYKHNVKRFK DGVEQLDDYC KMSRERAEIE AKYSKMLSQH 60
AEKWRAHVDR TVSAGSVKTV WNELIGEATA LSRVHNSLKD CLIDDIVNET TTYRKNSLHT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTCGTCTAT TTCACTCGAA TCGTCGATCT ATTAAAACAT GAGCTGTTTA CCATGGTGAG 60
TAGATTTTGC CTGTTAATGT TTCTGTTAAT CAAAAATATT AATTGTGTTT TTACTTTCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR031160--F_BAR
IPR001060--FCH_dom
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005769--C:early endosome
GO:0055037--C:recycling endosome
GO:0055038--C:recycling endosome membrane
GO:0032456--P:endocytic recycling
GO:0030100--P:regulation of endocytosis

KEGG

cel:CELE_F45E1.7

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001887	Ailuropoda melanoleuca	31.81	9.00e-56	209.00
IUUC-Apl-003667	Anas platyrhynchos	29.47	2.00e-55	208.00
IUUC-Aca-004251	Anolis carolinensis	28.57	2.00e-50	192.00
IUUC-Ame-011756	Astyanax mexicanus	29.39	8.00e-57	213.00
IUUC-Bta-013193	Bos taurus	32.36	8.00e-53	199.00
IUUC-Cja-018756	Callithrix jacchus	32.04	9.00e-53	199.00
IUUC-Cfa-020545	Canis familiaris	32.24	6.00e-58	217.00
IUUC-Cpo-022000	Cavia porcellus	32.25	2.00e-63	235.00
IUUC-Csa-023701	Chlorocebus sabaeus	30.04	5.00e-51	193.00
IUUC-Cin-025707	Ciona intestinalis	28.51	9.00e-51	192.00
IUUC-Csv-026244	Ciona savignyi	25.09	3.00e-15	73.60
IUUC-Dre-027456	Danio rerio	30.52	5.00e-58	217.00
IUUC-Dno-029429	Dasypus novemcinctus	31.32	8.00e-48	184.00
IUUC-Dor-030122	Dipodomys ordii	30.27	2.00e-51	195.00
IUUC-Dme-032120	Drosophila melanogaster	32.82	3.00e-49	187.00
IUUC-Eca-033367	Equus caballus	33.33	6.00e-56	210.00
IUUC-Eeu-034821	Erinaceus europaeus	26.67	4.00e-34	137.00
IUUC-Fca-036314	Felis catus	29.84	3.00e-51	194.00
IUUC-Fal-037300	Ficedula albicollis	29.84	1.00e-56	213.00
IUUC-Gmo-039681	Gadus morhua	28.63	2.00e-39	154.00
IUUC-Gga-040626	Gallus gallus	30.25	2.00e-53	202.00
IUUC-Gac-042262	Gasterosteus aculeatus	30.17	7.00e-52	196.00
IUUC-Ggo-044841	Gorilla gorilla	32.64	4.00e-53	200.00
IUUC-Hsa-046411	Homo sapiens	32.43	2.00e-52	198.00
IUUC-Itr-048856	Ictidomys tridecemlineatus	30.66	3.00e-52	197.00
IUUC-Lch-050070	Latimeria chalumnae	28.37	1.00e-54	205.00
IUUC-Loc-051975	Lepisosteus oculatus	28.15	4.00e-54	204.00
IUUC-Laf-053839	Loxodonta africana	32.16	1.00e-56	212.00
IUUC-Mcc-055783	Macaca mulatta	32.22	7.00e-52	196.00
IUUC-Meu-056348	Macropus eugenii	30.56	2.00e-51	194.00
IUUC-Mga-059285	Meleagris gallopavo	29.75	7.00e-51	193.00
IUUC-Mmr-060827	Microcebus murinus	33.54	7.00e-57	213.00
IUUC-Mdo-062600	Monodelphis domestica	28.43	4.00e-51	194.00
IUUC-Mmu-064347	Mus musculus	29.75	1.00e-56	212.00
IUUC-Mpu-066864	Mustela putorius furo	30.25	2.00e-51	195.00
IUUC-Mlu-067826	Myotis lucifugus	32.64	2.00e-57	215.00
IUUC-Nle-069797	Nomascus leucogenys	32.22	4.00e-52	197.00
IUUC-Opr-071050	Ochotona princeps	30.41	5.00e-43	167.00
IUUC-Ont-072188	Oreochromis niloticus	30.67	5.00e-54	204.00
IUUC-Oan-073256	Ornithorhynchus anatinus	31.25	4.00e-44	170.00
IUUC-Ocu-074425	Oryctolagus cuniculus	32.85	6.00e-53	200.00
IUUC-Ola-087188	Oryzias latipes	29.77	2.00e-41	161.00
IUUC-Oga-088856	Otolemur garnettii	29.63	1.00e-49	189.00
IUUC-Oar-089806	Ovis aries	32.36	4.00e-53	201.00
IUUC-Ptr-091111	Pan troglodytes	32.43	5.00e-52	197.00
IUUC-Pan-092056	Papio anubis	30.04	5.00e-51	193.00
IUUC-Psi-093704	Pelodiscus sinensis	32.22	7.00e-58	216.00
IUUC-Pfo-097281	Poecilia formosa	30.04	2.00e-50	192.00
IUUC-Pab-098202	Pongo abelii	29.84	2.00e-50	191.00
IUUC-Pca-100881	Procavia capensis	29.84	6.00e-49	187.00
IUUC-Pva-102181	Pteropus vampyrus	29.90	2.00e-50	192.00
IUUC-Rno-105431	Rattus norvegicus	33.13	1.00e-57	216.00
IUUC-Sha-106641	Sarcophilus harrisii	31.61	4.00e-55	207.00
IUUC-Sar-113461	Sorex araneus	28.98	4.00e-48	184.00
IUUC-Ssc-115349	Sus scrofa	33.26	1.00e-52	199.00
IUUC-Tgu-116876	Taeniopygia guttata	31.60	2.00e-53	201.00
IUUC-Tru-118306	Takifugu rubripes	28.36	2.00e-46	179.00
IUUC-Tsy-118901	Tarsius syrichta	28.41	2.00e-26	112.00
IUUC-Tni-120717	Tetraodon nigroviridis	35.43	1.00e-39	156.00
IUUC-Ttr-129069	Tursiops truncatus	29.75	5.00e-49	187.00
IUUC-Vpa-130760	Vicugna pacos	30.46	2.00e-24	105.00
IUUC-Xtr-132925	Xenopus tropicalis	30.67	3.00e-59	221.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence