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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063790
UUCD1 version UUC-MuM-00814
Ensembl Protein ID ENSMUSP00000099837.4
UniProt Accession Q8VEM1; Q80VL7; Q9QZQ6; GOLI_MOUSE
Genbank Protein ID AAF05310.1; CAI25115.1; CAI25115.1; CAI24372.1; CAI24372.1; AAH18199.1; AAH48901.2
Protein Name E3 ubiquitin-protein ligase RNF130; G1-related zinc finger protein; Goliath homolog; RING finger protein 130; RING-type E3 ubiquitin transferase RNF130
Genbank Nucleotide ID AF171875; AL627187; AL645913; AL645913; AL627187; BC018199; BC048901
Gene Name Rnf130; G1rp
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000020376.16 ENSMUST00000054684.13 ENSMUSP00000056345.7
ENSMUSG00000020376.16 ENSMUST00000102776.4 ENSMUSP00000099837.4
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACRepTar
RAID2
Protein-protein Interaction
IIDiRefIndexMentha
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 2.90e-07 32.0 264 305
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C e++   d ++vlpC+Hvfh++C+  w       s + +CP C+
   Q: 264  CAVCIESYkqNDVVRVLPCKHVFHKSCVDPW------LSEHCTCPMCK 305
           ********76666******************......**********6 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Acts as an E3 ubiquitin-protein ligase (By similarity). May have a role during the programmed cell death of hematopoietic cells.
 Acts as an E3 ubiquitin-protein ligase (By similarity). May have a role during the programmed cell death of hematopoietic cells.
Protein Sequence
(Fasta)
MSGAARAGPA RLAALALLTC SLWPTRADNA SQEYYTALIN VTVQEPGRGT PLTFRIDRGR 60
YGLDSPKAEV RGQVLAPLPI HGVADHLGCD PQTRFFVPPN IKQWIALLQR GNCTFKEKIS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063790|E3,RING|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ACCGGCCCCG GAGCCCGGTC CGCGAGCGGC GGCGGCGGCG GCGGCCGGAG GGACCATGAG 60
CGGCGCGGCG CGAGCGGGCC CGGCCCGGCT CGCGGCGCTG GCCCTGCTGA CTTGCAGCCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063790|E3,RING|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0053--Apoptosis
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0325--Glycoprotein
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0732--Signal
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50089--ZF_RING_2
Pfam

PF02225--PA
PF13639--zf-RING_2
SMART

SM00184--RING
Gene Ontology

GO:0005737--C:cytoplasm
GO:0016021--C:integral component of membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0012501--P:programmed cell death
KEGG mmu:59044
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001953 Ailuropoda melanoleuca 97.92 0.00e+00 690.00
IUUC-Apl-003520 Anas platyrhynchos 88.29 9.00e-179 619.00
IUUC-Aca-005099 Anolis carolinensis 79.50 1.00e-180 625.00
IUUC-Afu-009087 Aspergillus fumigatus 30.08 1.00e-13 69.70
IUUC-Ame-010838 Astyanax mexicanus 68.23 1.00e-143 503.00
IUUC-Bta-013574 Bos taurus 97.76 0.00e+00 823.00
IUUC-Cja-019048 Callithrix jacchus 94.51 0.00e+00 813.00
IUUC-Cfa-020217 Canis familiaris 97.97 0.00e+00 703.00
IUUC-Cpo-021540 Cavia porcellus 96.46 0.00e+00 682.00
IUUC-Csa-023073 Chlorocebus sabaeus 98.50 0.00e+00 828.00
IUUC-Cho-024861 Choloepus hoffmanni 95.54 0.00e+00 673.00
IUUC-Dre-028252 Danio rerio 68.95 1.00e-153 536.00
IUUC-Dno-029343 Dasypus novemcinctus 97.83 3.00e-162 563.00
IUUC-Dor-030591 Dipodomys ordii 98.51 0.00e+00 693.00
IUUC-Ete-032447 Echinops telfairi 96.73 0.00e+00 640.00
IUUC-Eca-034368 Equus caballus 98.20 0.00e+00 684.00
IUUC-Eeu-034965 Erinaceus europaeus 88.99 8.00e-177 612.00
IUUC-Fca-036053 Felis catus 98.22 0.00e+00 691.00
IUUC-Fal-037232 Ficedula albicollis 85.20 0.00e+00 694.00
IUUC-Gmo-039437 Gadus morhua 64.87 9.00e-130 456.00
IUUC-Gga-041046 Gallus gallus 82.32 1.00e-180 625.00
IUUC-Gac-042488 Gasterosteus aculeatus 60.44 9.00e-133 466.00
IUUC-Ggo-044560 Gorilla gorilla 98.50 0.00e+00 687.00
IUUC-Hsa-046224 Homo sapiens 98.50 0.00e+00 828.00
IUUC-Itr-048004 Ictidomys tridecemlineatus 98.81 0.00e+00 698.00
IUUC-Lch-050557 Latimeria chalumnae 75.00 3.00e-177 614.00
IUUC-Loc-052249 Lepisosteus oculatus 72.18 2.00e-176 611.00
IUUC-Laf-053702 Loxodonta africana 97.98 0.00e+00 792.00
IUUC-Mcc-054898 Macaca mulatta 97.83 0.00e+00 755.00
IUUC-Meu-056040 Macropus eugenii 71.39 4.00e-146 511.00
IUUC-Mga-059957 Meleagris gallopavo 86.51 1.00e-179 622.00
IUUC-Mdo-061837 Monodelphis domestica 92.37 0.00e+00 734.00
IUUC-Mpu-066143 Mustela putorius furo 97.92 0.00e+00 690.00
IUUC-Mlu-067291 Myotis lucifugus 96.73 0.00e+00 657.00
IUUC-Nle-069370 Nomascus leucogenys 96.85 0.00e+00 771.00
IUUC-Opr-070433 Ochotona princeps 78.12 1.00e-177 615.00
IUUC-Ont-071771 Oreochromis niloticus 58.93 3.00e-115 408.00
IUUC-Oan-073414 Ornithorhynchus anatinus 92.75 7.00e-156 542.00
IUUC-Ocu-074318 Oryctolagus cuniculus 95.91 0.00e+00 820.00
IUUC-Ola-086879 Oryzias latipes 65.70 1.00e-114 406.00
IUUC-Oga-088211 Otolemur garnettii 96.75 0.00e+00 781.00
IUUC-Oar-089978 Ovis aries 97.47 0.00e+00 805.00
IUUC-Ptr-091586 Pan troglodytes 98.50 0.00e+00 828.00
IUUC-Psi-094023 Pelodiscus sinensis 84.73 0.00e+00 697.00
IUUC-Pab-098663 Pongo abelii 97.03 0.00e+00 754.00
IUUC-Pca-100960 Procavia capensis 96.43 0.00e+00 645.00
IUUC-Pva-102567 Pteropus vampyrus 95.25 0.00e+00 723.00
IUUC-Rno-104966 Rattus norvegicus 94.07 0.00e+00 656.00
IUUC-Sha-106505 Sarcophilus harrisii 93.84 6.00e-148 516.00
IUUC-Sja-107946 Schizosaccharomyces japonicus 40.62 4.00e-13 68.20
IUUC-Ssc-116294 Sus scrofa 98.53 1.00e-160 558.00
IUUC-Tgu-117464 Taeniopygia guttata 85.71 0.00e+00 700.00
IUUC-Tni-120175 Tetraodon nigroviridis 58.31 6.00e-112 397.00
IUUC-Tbe-128124 Tupaia belangeri 72.02 3.00e-136 477.00
IUUC-Ttr-128752 Tursiops truncatus 98.21 0.00e+00 686.00
IUUC-Vpa-130764 Vicugna pacos 87.80 3.00e-172 597.00
IUUC-Xtr-132343 Xenopus tropicalis 77.69 3.00e-179 621.00
Created Date 25-Jun-2017

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