iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-024060

Ensembl Protein ID

ENSCSAP00000009803.1

UniProt Accession

A0A0D9RMG4; A0A0D9RMG4_CHLSB

Genbank Protein ID

ENSCSAP00000009803

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01160837

Gene Name

FBXO18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000013644.1	ENSCSAT00000011740.1	ENSCSAP00000009803.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	98.04	0.00e+00	1875.00	IUUC-Hsa-046650
E3 adaptor/Cullin RING/SCF/F-box	29.14	2.00e-42	169.00	IUUC-Spo-108147

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MAKSNSVGQD SCQDSEGDMI FPAESSCALP QEGSGEAWLG SSGSAPPSRK RSRSSEEESN 60
QATGTSLWDG VSKKAPRHHL TVPCTRPREA RQEAEDSTSR LSEESGETDQ DAGDVGPDPI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCAGGGACG TCAAAGATGT ATCCCTGAGT TCTTCCTAGC AGGCAAGCGG CCGTGCACCA 60
ATGACATGGC CAAAAGCAAT TCTGTTGGCC AGGACAGCTG TCAGGACTCT GAGGGTGACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014017--DNA_helicase_UvrD-like_C
IPR000212--DNA_helicase_UvrD/REP
IPR001810--F-box_dom
IPR027417--P-loop_NTPase

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF13361--UvrD_C

Gene Ontology

GO:0000785--C:chromatin
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0043138--F:3'-5' DNA helicase activity
GO:0005524--F:ATP binding
GO:0004003--F:ATP-dependent DNA helicase activity
GO:0015616--F:DNA translocase activity
GO:0003690--F:double-stranded DNA binding
GO:0003697--F:single-stranded DNA binding
GO:0008219--P:cell death
GO:0006974--P:cellular response to DNA damage stimulus
GO:0000737--P:DNA catabolic process, endonucleolytic
GO:0035562--P:negative regulation of chromatin binding
GO:2000042--P:negative regulation of double-strand break repair via homologous recombination
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0001934--P:positive regulation of protein phosphorylation
GO:0016567--P:protein ubiquitination
GO:0031297--P:replication fork processing
GO:0048478--P:replication fork protection
GO:0072429--P:response to intra-S DNA damage checkpoint signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000424	Aegilops tauschii	26.40	1.00e-04	42.70
IUUC-Aml-001396	Ailuropoda melanoleuca	92.79	0.00e+00	1840.00
IUUC-Atr-002826	Amborella trichopoda	40.00	1.00e-03	39.30
IUUC-Apl-003317	Anas platyrhynchos	54.19	0.00e+00	938.00
IUUC-Aca-004498	Anolis carolinensis	54.17	0.00e+00	955.00
IUUC-Aly-006174	Arabidopsis lyrata	33.33	2.00e-04	37.70
IUUC-Ath-007293	Arabidopsis thaliana	24.19	5.00e-03	37.40
IUUC-Ani-009226	Aspergillus nidulans	32.50	2.00e-06	48.10
IUUC-Ate-010526	Aspergillus terreus	38.24	1.00e-03	38.90
IUUC-Ame-011808	Astyanax mexicanus	58.82	2.00e-133	468.00
IUUC-Bta-013250	Bos taurus	90.23	0.00e+00	1793.00
IUUC-Bol-015348	Brassica oleracea	37.68	4.00e-03	37.70
IUUC-Cja-019638	Callithrix jacchus	97.43	0.00e+00	1974.00
IUUC-Cfa-020195	Canis familiaris	93.21	0.00e+00	1887.00
IUUC-Cpo-022269	Cavia porcellus	87.85	0.00e+00	1713.00
IUUC-Cre-022611	Chlamydomonas reinhardtii	40.28	4.00e-08	53.90
IUUC-Cho-025003	Choloepus hoffmanni	89.14	0.00e+00	726.00
IUUC-Cin-025694	Ciona intestinalis	27.70	6.00e-30	125.00
IUUC-Dre-028083	Danio rerio	50.06	0.00e+00	865.00
IUUC-Dno-029203	Dasypus novemcinctus	88.40	0.00e+00	1686.00
IUUC-Dor-030477	Dipodomys ordii	97.19	0.00e+00	793.00
IUUC-Ete-032861	Echinops telfairi	89.09	0.00e+00	1749.00
IUUC-Eca-033205	Equus caballus	93.11	0.00e+00	1883.00
IUUC-Eeu-034784	Erinaceus europaeus	86.49	0.00e+00	1224.00
IUUC-Fca-035797	Felis catus	92.81	0.00e+00	1848.00
IUUC-Gmo-038855	Gadus morhua	46.08	2.00e-125	443.00
IUUC-Gga-040326	Gallus gallus	52.79	0.00e+00	962.00
IUUC-Gac-042240	Gasterosteus aculeatus	46.96	0.00e+00	735.00
IUUC-Ggo-045050	Gorilla gorilla	94.27	0.00e+00	1810.00
IUUC-Hsa-046650	Homo sapiens	97.32	0.00e+00	1904.00
IUUC-Itr-047965	Ictidomys tridecemlineatus	97.67	0.00e+00	784.00
IUUC-Lch-050231	Latimeria chalumnae	49.11	3.00e-164	572.00
IUUC-Loc-051884	Lepisosteus oculatus	54.00	0.00e+00	978.00
IUUC-Lma-053267	Leptosphaeria maculans	22.53	3.00e-04	41.20
IUUC-Laf-053843	Loxodonta africana	91.87	0.00e+00	1830.00
IUUC-Mcc-055570	Macaca mulatta	98.87	0.00e+00	1949.00
IUUC-Meu-056798	Macropus eugenii	67.68	2.00e-154	540.00
IUUC-Mtr-057915	Medicago truncatula	38.24	4.00e-05	44.30
IUUC-Mga-059648	Meleagris gallopavo	58.51	0.00e+00	914.00
IUUC-Mmr-060757	Microcebus murinus	93.32	0.00e+00	1812.00
IUUC-Mdo-061913	Monodelphis domestica	69.86	0.00e+00	1395.00
IUUC-Mmu-064337	Mus musculus	91.15	0.00e+00	1837.00
IUUC-Mpu-066483	Mustela putorius furo	91.14	0.00e+00	1839.00
IUUC-Mlu-068204	Myotis lucifugus	86.24	0.00e+00	1713.00
IUUC-Ncr-068735	Neurospora crassa	35.94	7.00e-03	36.60
IUUC-Nle-070053	Nomascus leucogenys	98.46	0.00e+00	1888.00
IUUC-Opr-070588	Ochotona princeps	86.42	0.00e+00	1723.00
IUUC-Ont-072655	Oreochromis niloticus	46.42	0.00e+00	764.00
IUUC-Oan-073351	Ornithorhynchus anatinus	64.22	0.00e+00	1266.00
IUUC-Ocu-074465	Oryctolagus cuniculus	91.79	0.00e+00	1751.00
IUUC-Obr-076710	Oryza brachyantha	35.29	5.00e-03	37.40
IUUC-Oin-079176	Oryza indica	23.62	2.00e-05	43.90
IUUC-Olo-080505	Oryza longistaminata	30.14	6.00e-03	38.10
IUUC-Opu-083155	Oryza punctata	47.50	4.00e-03	37.00
IUUC-Olu-087831	Ostreococcus lucimarinus	31.72	2.00e-65	244.00
IUUC-Oga-089088	Otolemur garnettii	92.58	0.00e+00	1791.00
IUUC-Oar-089870	Ovis aries	89.20	0.00e+00	1771.00
IUUC-Ptr-090957	Pan troglodytes	98.44	0.00e+00	1885.00
IUUC-Pan-092632	Papio anubis	98.97	0.00e+00	1900.00
IUUC-Psi-093035	Pelodiscus sinensis	57.49	0.00e+00	1095.00
IUUC-Pno-094870	Phaeosphaeria nodorum	25.27	7.00e-05	43.10
IUUC-Ppa-095660	Physcomitrella patens	38.36	9.00e-04	39.70
IUUC-Pfo-096902	Poecilia formosa	44.57	0.00e+00	691.00
IUUC-Pab-098206	Pongo abelii	98.25	0.00e+00	1773.00
IUUC-Pop-098801	Populus trichocarpa	37.68	1.00e-04	42.70
IUUC-Pca-100238	Procavia capensis	86.21	0.00e+00	1699.00
IUUC-Ppe-101748	Prunus persica	33.82	5.00e-03	37.00
IUUC-Pva-103182	Pteropus vampyrus	89.61	0.00e+00	1737.00
IUUC-Pte-104033	Pyrenophora teres	24.71	3.00e-04	41.20
IUUC-Pyt-104599	Pyrenophora triticirepentis	24.29	2.00e-04	41.60
IUUC-Rno-105141	Rattus norvegicus	91.15	0.00e+00	1842.00
IUUC-Sce-106341	Saccharomyces cerevisiae	25.76	3.00e-03	37.40
IUUC-Sha-106827	Sarcophilus harrisii	69.65	0.00e+00	1393.00
IUUC-Sja-107882	Schizosaccharomyces japonicus	29.20	1.00e-43	172.00
IUUC-Spo-108147	Schizosaccharomyces pombe	29.14	1.00e-42	168.00
IUUC-Ssl-108584	Sclerotinia sclerotiorum	25.25	2.00e-04	41.60
IUUC-Sly-111170	Solanum lycopersicum	37.88	6.00e-03	35.80
IUUC-Sre-115025	Sporisorium reilianum	34.39	3.00e-39	157.00
IUUC-Ssc-116188	Sus scrofa	94.45	0.00e+00	1284.00
IUUC-Tgu-116612	Taeniopygia guttata	57.59	5.00e-163	567.00
IUUC-Tsy-119560	Tarsius syrichta	83.47	5.00e-118	419.00
IUUC-Tni-120734	Tetraodon nigroviridis	45.71	0.00e+00	714.00
IUUC-Tca-121338	Theobroma cacao	31.78	3.00e-03	38.10
IUUC-Tre-122089	Trichoderma reesei	40.74	2.00e-04	41.20
IUUC-Tae-123548	Triticum aestivum	38.24	3.00e-04	38.50
IUUC-Tme-127009	Tuber melanosporum	23.33	6.00e-04	40.00
IUUC-Tbe-127431	Tupaia belangeri	91.86	0.00e+00	1555.00
IUUC-Ttr-128744	Tursiops truncatus	88.28	0.00e+00	1755.00
IUUC-Uma-129536	Ustilago maydis	34.78	2.00e-40	160.00
IUUC-Vpa-130123	Vicugna pacos	75.42	8.00e-74	271.00
IUUC-Vvi-131025	Vitis vinifera	36.76	7.00e-04	40.00
IUUC-Xtr-132902	Xenopus tropicalis	58.26	0.00e+00	1019.00
IUUC-Xma-133978	Xiphophorus maculatus	45.84	7.00e-154	537.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence