iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-136452

Ensembl Protein ID

ENSDARP00000059034.6

UniProt Accession

A0AUR5; MINY3_DANRE

Genbank Protein ID

BC124766

Protein Name

Ubiquitin carboxyl-terminal hydrolase MINDY-3;Deubiquitinating enzyme MINDY-3;Protein CARP

Genbank Nucleotide ID

AAI24767.1

Gene Name

mindy3;carp;fam188a;zgc:153892

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000028715.7	ENSDART00000059035.6	ENSDARP00000059034.6

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/MIU	74.22	0.00e+00	664.00	IUUC-Hsa-136747
DUB/MINDY	74.22	0.00e+00	664.00	IUUC-Hsa-136747

Active Site

Position(s)	Description	Evidence
51	Nucleophile	{ECO:0000250\|UniProtKB:Q8N5J2}
288	Proton acceptor	{ECO:0000250\|UniProtKB:Q8N5J2}

Organism

Danio rerio

Functional Description
(View)

Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

Protein Sequence
(Fasta)

MSDTNKEVVD LVWGRPSGGG VPASLFRRWS QGFVFSETER SALEQFEGGP CAVIAPVQAF 60
LLKNILFNTE GLNWKDISEE EQRTVLCSTL SEILELACLN KSQAFHLVTW PHAKTTDNSD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTAGTAAATA AACTGAATGG ACCACAGAGC GGTCTGCTTT ACCCATAACG AGCAATTTTC 60
ATTGATTTTT TCCTATTTTT TCTAGGTGTT GTGGAGTGCA ACTGACAGCC GTTGGCTACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0053--Apoptosis
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0539--Nucleus
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR025257--DUF4205
IPR011992--EF-hand-dom_pair

Pfam

PF13898--DUF4205

SMART

SM01174--DUF4205

Gene Ontology

GO:0005634--C:nucleus
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0006915--P:apoptotic process

KEGG

dre:777708

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-136377	Aegilops tauschii	29.89	7.00e-40	158.00
IUUC-Aml-136379	Ailuropoda melanoleuca	73.38	0.00e+00	667.00
IUUC-Atr-136383	Amborella trichopoda	30.50	2.00e-38	154.00
IUUC-Apl-136385	Anas platyrhynchos	74.39	1.00e-163	569.00
IUUC-Aca-136389	Anolis carolinensis	72.93	0.00e+00	691.00
IUUC-Ame-136407	Astyanax mexicanus	88.47	0.00e+00	822.00
IUUC-Bta-136411	Bos taurus	73.09	0.00e+00	667.00
IUUC-Bdi-136416	Brachypodium distachyon	30.05	7.00e-43	169.00
IUUC-Bra-136421	Brassica rapa	29.27	1.00e-39	158.00
IUUC-Cja-136424	Callithrix jacchus	74.44	0.00e+00	676.00
IUUC-Cfa-136428	Canis familiaris	72.77	9.00e-177	612.00
IUUC-Cpo-136432	Cavia porcellus	72.65	0.00e+00	667.00
IUUC-Csa-136438	Chlorocebus sabaeus	74.22	0.00e+00	677.00
IUUC-Cho-136444	Choloepus hoffmanni	75.65	3.00e-140	491.00
IUUC-Cin-136447	Ciona intestinalis	41.30	9.00e-94	337.00
IUUC-Csv-136448	Ciona savignyi	40.36	6.00e-92	331.00
IUUC-Dno-136456	Dasypus novemcinctus	72.87	0.00e+00	666.00
IUUC-Dor-136461	Dipodomys ordii	69.86	2.00e-146	511.00
IUUC-Dme-136466	Drosophila melanogaster	43.16	3.00e-108	385.00
IUUC-Ete-136467	Echinops telfairi	56.95	5.00e-141	494.00
IUUC-Eca-136471	Equus caballus	73.77	0.00e+00	674.00
IUUC-Eeu-136476	Erinaceus europaeus	68.16	2.00e-170	592.00
IUUC-Fca-136477	Felis catus	73.99	0.00e+00	673.00
IUUC-Fal-136481	Ficedula albicollis	72.36	0.00e+00	666.00
IUUC-Gmo-136486	Gadus morhua	76.73	0.00e+00	684.00
IUUC-Gga-136491	Gallus gallus	73.38	0.00e+00	686.00
IUUC-Gac-136495	Gasterosteus aculeatus	76.77	0.00e+00	697.00
IUUC-Gma-136499	Glycine max	28.94	1.00e-43	171.00
IUUC-Ggo-136502	Gorilla gorilla	70.54	2.00e-180	625.00
IUUC-Hsa-136747	Homo sapiens	74.22	0.00e+00	677.00
IUUC-Hvu-136508	Hordeum vulgare	31.80	6.00e-34	138.00
IUUC-Itr-136510	Ictidomys tridecemlineatus	68.08	2.00e-78	285.00
IUUC-Lch-136515	Latimeria chalumnae	75.95	0.00e+00	697.00
IUUC-Lpe-136518	Leersia perrieri	27.45	7.00e-35	142.00
IUUC-Loc-136521	Lepisosteus oculatus	79.51	0.00e+00	741.00
IUUC-Laf-136527	Loxodonta africana	72.42	0.00e+00	662.00
IUUC-Mcc-136530	Macaca mulatta	74.22	0.00e+00	677.00
IUUC-Meu-136534	Macropus eugenii	53.61	6.00e-81	294.00
IUUC-Mga-136543	Meleagris gallopavo	75.18	0.00e+00	647.00
IUUC-Mmr-136547	Microcebus murinus	73.99	0.00e+00	676.00
IUUC-Mdo-136551	Monodelphis domestica	73.32	0.00e+00	686.00
IUUC-Mmu-136555	Mus musculus	72.65	0.00e+00	660.00
IUUC-Mpu-136561	Mustela putorius furo	70.26	4.00e-139	487.00
IUUC-Mlu-136565	Myotis lucifugus	72.20	0.00e+00	661.00
IUUC-Nle-136572	Nomascus leucogenys	74.22	0.00e+00	677.00
IUUC-Opr-136576	Ochotona princeps	49.25	2.00e-92	333.00
IUUC-Ont-136579	Oreochromis niloticus	76.33	0.00e+00	691.00
IUUC-Oan-136582	Ornithorhynchus anatinus	73.54	0.00e+00	645.00
IUUC-Ocu-136585	Oryctolagus cuniculus	73.77	0.00e+00	671.00
IUUC-Oba-136589	Oryza barthii	27.62	1.00e-43	171.00
IUUC-Ogl-136593	Oryza glaberrima	27.62	1.00e-43	171.00
IUUC-Ogu-136595	Oryza glumaepatula	27.62	1.00e-43	171.00
IUUC-Oin-136597	Oryza indica	27.95	3.00e-42	166.00
IUUC-Olo-136599	Oryza longistaminata	27.62	2.00e-43	170.00
IUUC-Oni-136602	Oryza nivara	27.62	1.00e-43	171.00
IUUC-Opu-136604	Oryza punctata	27.62	3.00e-43	169.00
IUUC-Oru-136606	Oryza rufipogon	27.62	1.00e-43	171.00
IUUC-Osa-136608	Oryza sativa	30.30	1.00e-29	124.00
IUUC-Ola-136610	Oryzias latipes	77.13	0.00e+00	717.00
IUUC-Oga-136614	Otolemur garnettii	73.60	0.00e+00	673.00
IUUC-Oar-136619	Ovis aries	72.87	0.00e+00	666.00
IUUC-Ptr-136623	Pan troglodytes	74.22	0.00e+00	677.00
IUUC-Pan-136627	Papio anubis	74.22	0.00e+00	677.00
IUUC-Psi-136631	Pelodiscus sinensis	76.92	8.00e-165	572.00
IUUC-Pma-136635	Petromyzon marinus	70.21	1.00e-46	178.00
IUUC-Pfo-136641	Poecilia formosa	75.16	0.00e+00	705.00
IUUC-Pab-136645	Pongo abelii	74.22	0.00e+00	676.00
IUUC-Pca-136652	Procavia capensis	56.73	2.00e-139	489.00
IUUC-Ppe-136656	Prunus persica	28.76	1.00e-45	177.00
IUUC-Pva-136658	Pteropus vampyrus	67.71	3.00e-167	581.00
IUUC-Rno-136665	Rattus norvegicus	73.09	0.00e+00	666.00
IUUC-Sha-136671	Sarcophilus harrisii	73.99	0.00e+00	692.00
IUUC-Sit-136680	Setaria italica	26.76	2.00e-31	129.00
IUUC-Sly-136683	Solanum lycopersicum	27.61	4.00e-40	159.00
IUUC-Sar-136685	Sorex araneus	69.17	7.00e-150	523.00
IUUC-Sbi-136688	Sorghum bicolor	29.83	2.00e-43	170.00
IUUC-Ssc-136691	Sus scrofa	72.87	0.00e+00	670.00
IUUC-Tgu-136694	Taeniopygia guttata	75.90	0.00e+00	658.00
IUUC-Tru-136698	Takifugu rubripes	75.16	0.00e+00	709.00
IUUC-Tsy-136703	Tarsius syrichta	71.97	0.00e+00	634.00
IUUC-Tni-136706	Tetraodon nigroviridis	78.75	0.00e+00	720.00
IUUC-Tca-136711	Theobroma cacao	29.35	6.00e-45	175.00
IUUC-Tae-136714	Triticum aestivum	30.17	7.00e-43	168.00
IUUC-Tbe-136719	Tupaia belangeri	74.64	0.00e+00	626.00
IUUC-Ttr-136722	Tursiops truncatus	71.08	0.00e+00	647.00
IUUC-Vpa-136729	Vicugna pacos	74.88	0.00e+00	634.00
IUUC-Vvi-136732	Vitis vinifera	27.63	9.00e-44	171.00
IUUC-Xtr-136734	Xenopus tropicalis	68.31	3.00e-171	594.00
IUUC-Xma-136738	Xiphophorus maculatus	76.65	0.00e+00	715.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence