iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cja-019976

Ensembl Protein ID

ENSCJAP00000006624.1

UniProt Accession

F7HB70; F7HB70_CALJA

Genbank Protein ID

JAB03856.1; JAB22006.1; JAB26198.1; JAB36172.1; JAB52629.1

Protein Name

Ubiquilin-1 isoform 1

Genbank Nucleotide ID

ACFV01061722; GAMS01001130; GAMR01007734; GAMQ01005679; GAMP01000126

Gene Name

UBQLN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000003609.2	ENSCJAT00000006994.1	ENSCJAP00000006624.1
ENSCJAG00000003609.2	ENSCJAT00000006976.2	ENSCJAP00000006608.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	8.60e-10	39.4	547	584
ULD/UDP/UBQ/UBQ_PIM	8.70e-25	87.4	37	110

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAveyLl 39
           ++++leql +MGF +re++lqaL a++++++aA+e+Ll
   Q: 547  FQQQLEQLSAMGFlNREANLQALIATGGDINAAIERLL 584
           799**********************************9 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           mk+tvkt+k+ke e+ v e+++v+++Ke+i+k+++ + +q+ LI+aGkiLkD++tLs++gi+dg +vhlv+k+++
   Q: 37   MKVTVKTPKEKE-EFAVPENSSVQQFKEEISKRFKSHTDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQN 110
           99**********.***********************************************************987 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MAESGESGGP PGSQDSAAGA EGAGASAAAA SAEPKIMKVT VKTPKEKEEF AVPENSSVQQ 60
FKEEISKRFK SHTDQLVLIF AGKILKDQDT LSQHGIHDGL TVHLVIKTQN RPQDHSAQQT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATTTCGCTA ACCGTGACGT CATCTCTGCG CGCCGTTACA GTGCTTAACT ACAAACTGTG 60
ATTTAGTTTT TGGTGAAGGG AGTGGAAAAA AAAAAATGAA CTGACCTACC CCGCCCCATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0016235--C:aggresome
GO:0005776--C:autophagosome
GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0035973--P:aggrephagy
GO:0000045--P:autophagosome assembly
GO:0097352--P:autophagosome maturation
GO:0071456--P:cellular response to hypoxia
GO:1901340--P:negative regulation of store-operated calcium channel activity
GO:0034140--P:negative regulation of toll-like receptor 3 signaling pathway
GO:1903071--P:positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:0031398--P:positive regulation of protein ubiquitination
GO:1902175--P:regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

cjc:100394790

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000864	Aegilops tauschii	49.65	6.00e-38	152.00
IUUC-Aml-001461	Ailuropoda melanoleuca	95.53	0.00e+00	814.00
IUUC-Atr-002470	Amborella trichopoda	39.93	6.00e-45	175.00
IUUC-Apl-003241	Anas platyrhynchos	83.77	0.00e+00	723.00
IUUC-Aca-004511	Anolis carolinensis	80.11	0.00e+00	730.00
IUUC-Aly-005419	Arabidopsis lyrata	36.65	1.00e-51	197.00
IUUC-Ath-007350	Arabidopsis thaliana	34.28	9.00e-53	201.00
IUUC-Ani-009418	Aspergillus nidulans	25.12	1.00e-08	54.70
IUUC-Bta-013048	Bos taurus	94.21	0.00e+00	833.00
IUUC-Bdi-014506	Brachypodium distachyon	35.68	1.00e-52	200.00
IUUC-Bol-015326	Brassica oleracea	32.59	4.00e-55	209.00
IUUC-Bra-018014	Brassica rapa	38.75	8.00e-42	164.00
IUUC-Cel-018631	Caenorhabditis elegans	38.97	1.00e-67	250.00
IUUC-Cfa-020092	Canis familiaris	95.86	0.00e+00	840.00
IUUC-Cpo-022388	Cavia porcellus	95.68	0.00e+00	833.00
IUUC-Csa-024087	Chlorocebus sabaeus	98.36	0.00e+00	849.00
IUUC-Cho-024834	Choloepus hoffmanni	97.07	0.00e+00	850.00
IUUC-Cin-025136	Ciona intestinalis	51.10	8.00e-115	407.00
IUUC-Csv-026009	Ciona savignyi	53.08	2.00e-101	363.00
IUUC-Cne-026833	Cryptococcus neoformans	28.33	5.00e-14	72.00
IUUC-Cme-027155	Cyanidioschyzon merolae	58.10	1.00e-34	141.00
IUUC-Dno-028970	Dasypus novemcinctus	76.84	0.00e+00	674.00
IUUC-Dor-030519	Dipodomys ordii	94.42	0.00e+00	811.00
IUUC-Dse-031421	Dothistroma septosporum	27.96	3.00e-13	69.70
IUUC-Dme-032013	Drosophila melanogaster	46.03	1.00e-114	406.00
IUUC-Ete-032273	Echinops telfairi	95.09	0.00e+00	815.00
IUUC-Eca-033667	Equus caballus	94.91	0.00e+00	841.00
IUUC-Eeu-034727	Erinaceus europaeus	79.91	6.00e-159	554.00
IUUC-Fca-036179	Felis catus	92.99	0.00e+00	795.00
IUUC-Fal-037642	Ficedula albicollis	82.50	0.00e+00	782.00
IUUC-Gga-041264	Gallus gallus	83.36	0.00e+00	813.00
IUUC-Gma-042681	Glycine max	35.15	3.00e-45	176.00
IUUC-Ggo-044969	Gorilla gorilla	98.02	0.00e+00	828.00
IUUC-Hsa-046669	Homo sapiens	98.20	0.00e+00	860.00
IUUC-Hvu-047094	Hordeum vulgare	52.27	8.00e-09	52.40
IUUC-Itr-048337	Ictidomys tridecemlineatus	96.48	0.00e+00	690.00
IUUC-Lch-050192	Latimeria chalumnae	77.45	0.00e+00	681.00
IUUC-Lpe-051401	Leersia perrieri	38.41	2.00e-37	149.00
IUUC-Loc-052846	Lepisosteus oculatus	76.51	0.00e+00	673.00
IUUC-Lma-053152	Leptosphaeria maculans	30.86	1.00e-11	64.70
IUUC-Laf-054278	Loxodonta africana	94.23	0.00e+00	805.00
IUUC-Mcc-055680	Macaca mulatta	98.56	0.00e+00	860.00
IUUC-Meu-056414	Macropus eugenii	79.90	3.00e-158	551.00
IUUC-Mtr-058674	Medicago truncatula	39.52	1.00e-40	161.00
IUUC-Mga-059894	Meleagris gallopavo	82.44	0.00e+00	652.00
IUUC-Mmr-061094	Microcebus murinus	97.48	0.00e+00	835.00
IUUC-Mdo-062728	Monodelphis domestica	82.37	0.00e+00	779.00
IUUC-Mmu-064088	Mus musculus	86.49	0.00e+00	859.00
IUUC-Mac-065458	Musa acuminata	34.07	1.00e-45	177.00
IUUC-Mpu-066282	Mustela putorius furo	92.45	0.00e+00	808.00
IUUC-Mlu-068158	Myotis lucifugus	94.23	0.00e+00	801.00
IUUC-Nle-069321	Nomascus leucogenys	98.02	0.00e+00	860.00
IUUC-Opr-071098	Ochotona princeps	89.92	0.00e+00	637.00
IUUC-Oan-072808	Ornithorhynchus anatinus	86.83	0.00e+00	745.00
IUUC-Ocu-074301	Oryctolagus cuniculus	88.71	0.00e+00	798.00
IUUC-Oba-074973	Oryza barthii	38.31	2.00e-43	169.00
IUUC-Obr-076444	Oryza brachyantha	50.30	9.00e-33	135.00
IUUC-Ogl-077319	Oryza glaberrima	33.73	2.00e-45	177.00
IUUC-Ogu-078074	Oryza glumaepatula	31.73	4.00e-52	199.00
IUUC-Oin-079142	Oryza indica	33.49	2.00e-45	176.00
IUUC-Olo-080565	Oryza longistaminata	34.61	9.00e-49	187.00
IUUC-Ome-081155	Oryza meridionalis	45.67	4.00e-35	142.00
IUUC-Oni-082272	Oryza nivara	33.49	2.00e-45	176.00
IUUC-Opu-083241	Oryza punctata	35.18	4.00e-51	195.00
IUUC-Oru-085257	Oryza rufipogon	33.49	2.00e-45	176.00
IUUC-Osa-086257	Oryza sativa	33.73	2.00e-45	177.00
IUUC-Olu-087597	Ostreococcus lucimarinus	32.48	9.00e-26	111.00
IUUC-Oga-088495	Otolemur garnettii	96.22	0.00e+00	812.00
IUUC-Oar-089711	Ovis aries	93.72	0.00e+00	809.00
IUUC-Ptr-091439	Pan troglodytes	97.84	0.00e+00	854.00
IUUC-Pan-092641	Papio anubis	98.56	0.00e+00	860.00
IUUC-Psi-093518	Pelodiscus sinensis	82.58	0.00e+00	726.00
IUUC-Pma-094727	Petromyzon marinus	42.92	7.00e-53	201.00
IUUC-Ppa-095702	Physcomitrella patens	37.88	2.00e-43	170.00
IUUC-Pfo-096638	Poecilia formosa	67.39	9.00e-175	606.00
IUUC-Pab-098699	Pongo abelii	95.68	0.00e+00	852.00
IUUC-Pop-099549	Populus trichocarpa	34.48	6.00e-59	221.00
IUUC-Pca-100497	Procavia capensis	84.09	3.00e-136	478.00
IUUC-Ppe-101901	Prunus persica	31.81	4.00e-60	225.00
IUUC-Pva-102513	Pteropus vampyrus	83.70	3.00e-148	518.00
IUUC-Pgr-103261	Puccinia graminis	54.76	2.00e-07	50.10
IUUC-Rno-104908	Rattus norvegicus	87.16	0.00e+00	895.00
IUUC-Sce-106332	Saccharomyces cerevisiae	32.73	8.00e-17	81.30
IUUC-Sha-106881	Sarcophilus harrisii	84.70	0.00e+00	707.00
IUUC-Spo-108223	Schizosaccharomyces pombe	28.57	1.00e-11	63.50
IUUC-Smo-108910	Selaginella moellendorffii	33.26	1.00e-45	177.00
IUUC-Sit-110766	Setaria italica	38.39	5.00e-37	149.00
IUUC-Sly-111731	Solanum lycopersicum	30.55	5.00e-48	185.00
IUUC-Stu-112263	Solanum tuberosum	38.24	3.00e-41	163.00
IUUC-Sar-113648	Sorex araneus	90.19	0.00e+00	639.00
IUUC-Sbi-114307	Sorghum bicolor	38.64	1.00e-45	177.00
IUUC-Sre-115081	Sporisorium reilianum	24.40	3.00e-12	66.20
IUUC-Ssc-115820	Sus scrofa	96.94	0.00e+00	842.00
IUUC-Tgu-116845	Taeniopygia guttata	76.74	0.00e+00	693.00
IUUC-Tsy-119008	Tarsius syrichta	79.36	4.00e-157	548.00
IUUC-Tni-119780	Tetraodon nigroviridis	64.71	1.00e-171	596.00
IUUC-Tca-121558	Theobroma cacao	35.59	6.00e-55	208.00
IUUC-Tae-125518	Triticum aestivum	49.65	2.00e-38	153.00
IUUC-Tur-126248	Triticum urartu	49.65	3.00e-38	153.00
IUUC-Tme-127116	Tuber melanosporum	25.91	6.00e-09	55.50
IUUC-Tbe-127379	Tupaia belangeri	83.58	0.00e+00	679.00
IUUC-Ttr-128630	Tursiops truncatus	94.09	0.00e+00	849.00
IUUC-Uma-129639	Ustilago maydis	25.30	6.00e-12	65.50
IUUC-Vpa-130413	Vicugna pacos	71.12	5.00e-161	560.00
IUUC-Vvi-131599	Vitis vinifera	40.14	2.00e-42	167.00
IUUC-Xtr-132595	Xenopus tropicalis	79.15	0.00e+00	714.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence