iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-061892

UUCD1 version

UUC-MoD-00056

Ensembl Protein ID

ENSMODP00000015725.3

UniProt Accession

F6PLA6; F6PLA6_MONDO

Protein Name

Uncharacterized protein

Gene Name

SOCS7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000012566.3	ENSMODT00000016015.3	ENSMODP00000015725.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	6.10e-14	51.8	600	647

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
           +++ +++s++ SLqhLCR++Ir++++++++   + LPLPk L++Y++++ y
   Q: 600  LYPVSRFSNVKSLQHLCRFRIRQLVRIDHI---PDLPLPKPLISYIRKFYY 647
           567899*********************998...*************99976 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MQGAELRDGE AAAAAAAAAA ASYRVLSRLL GYGESASEPA PPPLPPPAPG HGPQPLPPTQ 60
SPVPPPPPPP FLPRPGPRGS RPPQLMVFRN VGRPPEEEEA AAAAGPGPGP SELLCPRHRC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGGGGG CCGAGCTCCG GGACGGCGAA GCAGCAGCGG CAGCGGCGGC AGCAGCGGCG 60
GCCTCGTACC GCGTCCTGAG CCGCCTGCTG GGCTACGGAG AATCAGCCTC GGAGCCTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028423--SOCS7
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0004860--F:protein kinase inhibitor activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0045444--P:fat cell differentiation
GO:0008286--P:insulin receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0021819--P:layer formation in cerebral cortex
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity
GO:0016567--P:protein ubiquitination
GO:0021942--P:radial glia guided migration of Purkinje cell

KEGG

mdo:100017282

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001668	Ailuropoda melanoleuca	86.37	0.00e+00	629.00
IUUC-Apl-003277	Anas platyrhynchos	91.78	4.00e-73	266.00
IUUC-Aca-004639	Anolis carolinensis	96.74	1.00e-107	381.00
IUUC-Ame-011301	Astyanax mexicanus	68.60	4.00e-129	454.00
IUUC-Bta-013483	Bos taurus	88.08	0.00e+00	644.00
IUUC-Cel-018643	Caenorhabditis elegans	30.30	2.00e-11	62.00
IUUC-Cja-019765	Callithrix jacchus	98.12	2.00e-160	558.00
IUUC-Cfa-020109	Canis familiaris	91.17	0.00e+00	648.00
IUUC-Cpo-021555	Cavia porcellus	90.15	1.00e-173	602.00
IUUC-Csa-023580	Chlorocebus sabaeus	86.90	6.00e-175	607.00
IUUC-Cho-024431	Choloepus hoffmanni	98.43	2.00e-71	262.00
IUUC-Cin-025413	Ciona intestinalis	47.02	6.00e-42	164.00
IUUC-Csv-026247	Ciona savignyi	45.21	6.00e-43	168.00
IUUC-Dre-028183	Danio rerio	69.19	3.00e-138	486.00
IUUC-Dno-028858	Dasypus novemcinctus	88.89	0.00e+00	672.00
IUUC-Dor-031071	Dipodomys ordii	77.67	5.00e-111	393.00
IUUC-Dme-031876	Drosophila melanogaster	43.15	5.00e-43	169.00
IUUC-Ete-032928	Echinops telfairi	69.02	7.00e-99	354.00
IUUC-Eca-033250	Equus caballus	89.11	2.00e-168	585.00
IUUC-Eeu-034946	Erinaceus europaeus	76.89	5.00e-47	182.00
IUUC-Fca-036589	Felis catus	91.33	3.00e-180	624.00
IUUC-Fal-037316	Ficedula albicollis	93.07	7.00e-112	396.00
IUUC-Gmo-038552	Gadus morhua	91.26	1.00e-53	201.00
IUUC-Gga-041248	Gallus gallus	96.22	2.00e-107	380.00
IUUC-Gac-041469	Gasterosteus aculeatus	83.47	9.00e-57	211.00
IUUC-Ggo-045282	Gorilla gorilla	97.80	1.00e-159	555.00
IUUC-Hsa-045926	Homo sapiens	86.69	1.00e-174	606.00
IUUC-Itr-048411	Ictidomys tridecemlineatus	78.30	5.00e-143	501.00
IUUC-Lch-049768	Latimeria chalumnae	69.04	2.00e-150	525.00
IUUC-Loc-051949	Lepisosteus oculatus	71.89	7.00e-130	457.00
IUUC-Laf-053410	Loxodonta africana	86.40	0.00e+00	628.00
IUUC-Mcc-054605	Macaca mulatta	79.09	3.00e-168	585.00
IUUC-Meu-056773	Macropus eugenii	82.08	3.00e-110	390.00
IUUC-Mmr-060927	Microcebus murinus	87.00	4.00e-176	611.00
IUUC-Mmu-064246	Mus musculus	79.90	4.00e-180	624.00
IUUC-Mpu-065995	Mustela putorius furo	89.08	2.00e-177	615.00
IUUC-Mlu-067526	Myotis lucifugus	89.31	0.00e+00	657.00
IUUC-Nle-069317	Nomascus leucogenys	92.86	8.00e-161	560.00
IUUC-Ont-072258	Oreochromis niloticus	65.19	4.00e-116	412.00
IUUC-Oan-073703	Ornithorhynchus anatinus	80.49	1.00e-36	143.00
IUUC-Ocu-074577	Oryctolagus cuniculus	82.06	0.00e+00	659.00
IUUC-Ola-086866	Oryzias latipes	52.38	7.00e-33	133.00
IUUC-Oga-088426	Otolemur garnettii	85.95	6.00e-179	620.00
IUUC-Oar-089407	Ovis aries	87.68	2.00e-180	624.00
IUUC-Ptr-091327	Pan troglodytes	93.63	2.00e-174	604.00
IUUC-Pan-092064	Papio anubis	93.87	1.00e-177	616.00
IUUC-Psi-093834	Pelodiscus sinensis	94.36	5.00e-154	536.00
IUUC-Pma-094253	Petromyzon marinus	53.33	2.00e-42	167.00
IUUC-Pfo-097100	Poecilia formosa	61.75	9.00e-115	407.00
IUUC-Pab-097695	Pongo abelii	81.59	1.00e-177	616.00
IUUC-Pca-100569	Procavia capensis	89.07	8.00e-167	580.00
IUUC-Pva-102784	Pteropus vampyrus	86.85	4.00e-179	620.00
IUUC-Rno-105485	Rattus norvegicus	79.90	0.00e+00	627.00
IUUC-Sha-106720	Sarcophilus harrisii	98.15	0.00e+00	644.00
IUUC-Sar-112975	Sorex araneus	83.33	6.00e-126	443.00
IUUC-Ssc-116369	Sus scrofa	86.93	5.00e-176	610.00
IUUC-Tgu-116867	Taeniopygia guttata	86.52	2.00e-124	438.00
IUUC-Tru-117562	Takifugu rubripes	64.18	2.00e-101	362.00
IUUC-Tsy-118999	Tarsius syrichta	91.82	8.00e-143	499.00
IUUC-Tni-120793	Tetraodon nigroviridis	58.33	2.00e-131	462.00
IUUC-Tbe-127671	Tupaia belangeri	97.69	8.00e-127	446.00
IUUC-Ttr-128491	Tursiops truncatus	75.74	7.00e-125	440.00
IUUC-Vpa-130104	Vicugna pacos	86.41	2.00e-165	575.00
IUUC-Xtr-132507	Xenopus tropicalis	80.58	7.00e-145	506.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence