iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Dme-032069

UUCD1 version

UUC-DrM-00157

Ensembl Protein ID

FBpp0087274

UniProt Accession

Q494G8; Q494G8_DROME

Genbank Protein ID

AAF58680.2; AAF58681.2; AAM68724.1; AAZ66315.1

Protein Name

F-box and leucine-rich repeat protein 6, isoform A; F-box and leucine-rich repeat protein 6, isoform B; F-box and leucine-rich repeat protein 6, isoform C; RE55062p

Genbank Nucleotide ID

AE013599; AE013599; AE013599; BT023808

Gene Name

Fbl6; fbl6; CG13213; Dmel_CG13213

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
FBgn0033609	FBtr0088178	FBpp0087274

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	33.49	1.00e-47	189.00	IUUC-Hsa-046499

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MSESLSSQVE ETKVSDDDGV KEKAEVSTAK DSAETAMEVE ADDTGGQQPE QSELLDKEKS 60
ATVDINTLTP STPSQTPPQL LAVETATSGS TAVIPENILS PPKSETQTDE TNTATSTSCS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTGTTGTGA TGTATCGATA CAACAACAAC ATCCCCAGCT TTCTATCTAC GTCGTTCGTT 60
GCAGCAAATA AATAAGTTTT AATTGATTGT GCGCCTTTAA AATGTACGAA TTGTGGCTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR006553--Leu-rich_rpt_Cys-con_subtyp

PROSITE

PS51450--LRR

Pfam

PF12937--F-box-like

SMART

SM00367--LRR_CC

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0032093--F:SAM domain binding
GO:2000060--P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0031647--P:regulation of protein stability
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

dme:Dmel_CG13213

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002047	Ailuropoda melanoleuca	32.59	1.00e-47	183.00
IUUC-Aca-004785	Anolis carolinensis	29.50	2.00e-19	88.60
IUUC-Ame-011690	Astyanax mexicanus	31.28	5.00e-19	87.80
IUUC-Bta-012781	Bos taurus	33.71	2.00e-50	192.00
IUUC-Cja-018799	Callithrix jacchus	28.04	2.00e-24	106.00
IUUC-Cfa-020518	Canis familiaris	33.56	9.00e-44	171.00
IUUC-Cpo-022012	Cavia porcellus	33.49	1.00e-48	186.00
IUUC-Csa-023717	Chlorocebus sabaeus	32.74	3.00e-38	151.00
IUUC-Dre-028685	Danio rerio	29.36	3.00e-43	169.00
IUUC-Dno-029881	Dasypus novemcinctus	31.09	6.00e-18	83.60
IUUC-Eca-034384	Equus caballus	33.26	1.00e-45	176.00
IUUC-Eeu-034885	Erinaceus europaeus	33.33	2.00e-33	135.00
IUUC-Fca-036109	Felis catus	33.02	1.00e-44	173.00
IUUC-Gmo-039122	Gadus morhua	30.50	4.00e-36	145.00
IUUC-Gac-042048	Gasterosteus aculeatus	30.45	4.00e-43	168.00
IUUC-Ggo-045521	Gorilla gorilla	33.49	3.00e-45	175.00
IUUC-Hsa-046499	Homo sapiens	33.49	1.00e-48	186.00
IUUC-Itr-048984	Ictidomys tridecemlineatus	33.49	6.00e-46	177.00
IUUC-Loc-052284	Lepisosteus oculatus	30.22	2.00e-47	183.00
IUUC-Laf-053367	Loxodonta africana	31.63	1.00e-38	153.00
IUUC-Mcc-055865	Macaca mulatta	33.49	4.00e-46	178.00
IUUC-Meu-056048	Macropus eugenii	31.93	5.00e-32	130.00
IUUC-Mmr-061506	Microcebus murinus	32.56	4.00e-42	165.00
IUUC-Mdo-062323	Monodelphis domestica	34.19	9.00e-49	187.00
IUUC-Mmu-063382	Mus musculus	31.95	2.00e-45	176.00
IUUC-Mpu-066188	Mustela putorius furo	32.93	6.00e-41	160.00
IUUC-Nle-069437	Nomascus leucogenys	33.02	5.00e-37	148.00
IUUC-Ont-072058	Oreochromis niloticus	30.43	1.00e-37	150.00
IUUC-Oan-072773	Ornithorhynchus anatinus	29.38	2.00e-40	159.00
IUUC-Ola-086656	Oryzias latipes	31.61	1.00e-26	112.00
IUUC-Oga-088299	Otolemur garnettii	32.72	1.00e-42	166.00
IUUC-Oar-089657	Ovis aries	33.17	2.00e-47	183.00
IUUC-Ptr-090950	Pan troglodytes	33.26	1.00e-44	173.00
IUUC-Pan-092741	Papio anubis	33.72	4.00e-46	178.00
IUUC-Psi-093324	Pelodiscus sinensis	32.47	9.00e-32	129.00
IUUC-Pma-094256	Petromyzon marinus	29.18	4.00e-18	85.10
IUUC-Pfo-096992	Poecilia formosa	30.21	1.00e-41	163.00
IUUC-Pca-100265	Procavia capensis	30.90	7.00e-20	90.50
IUUC-Pva-103253	Pteropus vampyrus	32.31	4.00e-37	148.00
IUUC-Rno-106011	Rattus norvegicus	32.87	2.00e-43	169.00
IUUC-Sha-106485	Sarcophilus harrisii	31.22	3.00e-45	175.00
IUUC-Ssc-115464	Sus scrofa	33.80	4.00e-45	174.00
IUUC-Tsy-119633	Tarsius syrichta	30.26	2.00e-10	59.70
IUUC-Ttr-128827	Tursiops truncatus	34.02	3.00e-46	178.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence