iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004346

Ensembl Protein ID

ENSACAP00000011870.3

UniProt Accession

G1KLV6; G1KLV6_ANOCA

Protein Name

Uncharacterized protein

Gene Name

PHF8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000011904.3	ENSACAT00000012114.3	ENSACAP00000011870.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.10e-09	36.8	6	54

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C+ +++ ++ ++eC+ C++wfH  C++ + e+   n + + Cp+C+
   Q: 6    VYC-LCRLPYDVTRFMIECDVCQDWFHGSCVGVE-EDAAANIDLYHCPNCQ 54
           69*.******************************.*******99******6 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MASVPVYCLC RLPYDVTRFM IECDVCQDWF HGSCVGVEED AAANIDLYHC PNCQLLHGPS 60
VMKRRRGTSK HPDSSVSKEV GKTVKTGSTQ FVKELRSRTF PSADEVILKP SGAQLTVEFL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCTCTG TCCCGGTGTA TTGTCTCTGC CGCCTGCCCT ACGATGTCAC CCGCTTCATG 60
ATCGAGTGTG ACGTTTGCCA GGACTGGTTC CACGGCAGGT GAGCAGGAAC CTCATTGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003347--JmjC_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51184--JMJC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF02373--JmjC
PF00628--PHD

SMART

SM00558--JmjC
SM00249--PHD

Gene Ontology

GO:0031965--C:nuclear membrane
GO:0005730--C:nucleolus
GO:0003682--F:chromatin binding
GO:0071558--F:histone demethylase activity (H3-K27 specific)
GO:0051864--F:histone demethylase activity (H3-K36 specific)
GO:0032454--F:histone demethylase activity (H3-K9 specific)
GO:0035575--F:histone demethylase activity (H4-K20 specific)
GO:0005506--F:iron ion binding
GO:0008270--F:zinc ion binding
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0061188--P:negative regulation of chromatin silencing at rDNA
GO:0045943--P:positive regulation of transcription from RNA polymerase I promoter

KEGG

acs:100566919

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002427	Ailuropoda melanoleuca	66.63	0.00e+00	1050.00
IUUC-Aly-005443	Arabidopsis lyrata	34.62	6.00e-11	60.80
IUUC-Acl-008303	Aspergillus clavatus	32.64	5.00e-67	249.00
IUUC-Afl-008579	Aspergillus flavus	28.84	2.00e-29	124.00
IUUC-Afu-008903	Aspergillus fumigatus	31.31	2.00e-66	247.00
IUUC-Ani-009279	Aspergillus nidulans	31.70	2.00e-65	244.00
IUUC-Ang-009645	Aspergillus niger	28.84	6.00e-65	242.00
IUUC-Aor-010233	Aspergillus oryzae	31.67	8.00e-66	245.00
IUUC-Ate-010345	Aspergillus terreus	32.53	4.00e-69	256.00
IUUC-Ame-010945	Astyanax mexicanus	63.05	0.00e+00	1060.00
IUUC-Bol-015574	Brassica oleracea	36.05	1.00e-11	63.20
IUUC-Bra-017900	Brassica rapa	35.71	1.00e-10	60.50
IUUC-Cja-018757	Callithrix jacchus	47.23	6.00e-170	591.00
IUUC-Cfa-021156	Canis familiaris	66.97	0.00e+00	1088.00
IUUC-Cpo-022284	Cavia porcellus	68.38	0.00e+00	1098.00
IUUC-Cre-022934	Chlamydomonas reinhardtii	40.98	2.00e-10	58.50
IUUC-Csa-023515	Chlorocebus sabaeus	68.44	0.00e+00	1109.00
IUUC-Cme-027118	Cyanidioschyzon merolae	29.77	9.00e-51	194.00
IUUC-Dre-028423	Danio rerio	63.18	0.00e+00	1056.00
IUUC-Dno-029446	Dasypus novemcinctus	85.10	0.00e+00	856.00
IUUC-Dse-031402	Dothistroma septosporum	33.25	2.00e-62	234.00
IUUC-Ete-032380	Echinops telfairi	85.53	0.00e+00	859.00
IUUC-Eca-034302	Equus caballus	85.31	0.00e+00	861.00
IUUC-Fca-035578	Felis catus	67.95	0.00e+00	1107.00
IUUC-Gmo-038789	Gadus morhua	63.92	0.00e+00	1040.00
IUUC-Gac-041666	Gasterosteus aculeatus	64.26	0.00e+00	1024.00
IUUC-Gma-042998	Glycine max	34.25	1.00e-11	62.80
IUUC-Ggo-044712	Gorilla gorilla	68.14	0.00e+00	1102.00
IUUC-Hsa-045724	Homo sapiens	68.75	0.00e+00	1109.00
IUUC-Kpa-049384	Komagataella pastoris	32.70	5.00e-59	221.00
IUUC-Lch-049793	Latimeria chalumnae	84.45	0.00e+00	855.00
IUUC-Lma-053190	Leptosphaeria maculans	30.84	2.00e-67	251.00
IUUC-Laf-053656	Loxodonta africana	69.25	0.00e+00	1114.00
IUUC-Mcc-055658	Macaca mulatta	68.44	0.00e+00	1109.00
IUUC-Mtr-057679	Medicago truncatula	38.16	1.00e-12	65.90
IUUC-Mla-058890	Melampsora laricipopulina	47.86	6.00e-74	270.00
IUUC-Mvi-060481	Microbotryum violaceum	39.20	3.00e-77	283.00
IUUC-Mmr-060993	Microcebus murinus	85.75	0.00e+00	863.00
IUUC-Mdo-062097	Monodelphis domestica	67.60	0.00e+00	1067.00
IUUC-Mmu-063909	Mus musculus	68.10	0.00e+00	1127.00
IUUC-Mpu-066429	Mustela putorius furo	67.76	0.00e+00	1105.00
IUUC-Mlu-067746	Myotis lucifugus	66.44	0.00e+00	1076.00
IUUC-Nfi-068537	Neosartorya fischeri	32.12	7.00e-67	249.00
IUUC-Nle-070143	Nomascus leucogenys	68.48	0.00e+00	1118.00
IUUC-Ont-072257	Oreochromis niloticus	62.94	0.00e+00	1016.00
IUUC-Oan-073654	Ornithorhynchus anatinus	72.15	0.00e+00	843.00
IUUC-Ocu-074417	Oryctolagus cuniculus	67.65	0.00e+00	1101.00
IUUC-Ola-087502	Oryzias latipes	64.24	0.00e+00	1041.00
IUUC-Oga-088662	Otolemur garnettii	85.75	0.00e+00	862.00
IUUC-Oar-090332	Ovis aries	67.39	0.00e+00	1102.00
IUUC-Ptr-091646	Pan troglodytes	67.24	0.00e+00	1018.00
IUUC-Pan-092122	Papio anubis	68.44	0.00e+00	1109.00
IUUC-Pma-094621	Petromyzon marinus	68.97	0.00e+00	661.00
IUUC-Pno-094984	Phaeosphaeria nodorum	33.33	3.00e-63	237.00
IUUC-Pfo-096107	Poecilia formosa	63.16	0.00e+00	1012.00
IUUC-Pab-097635	Pongo abelii	60.39	0.00e+00	910.00
IUUC-Pop-099324	Populus trichocarpa	40.00	4.00e-11	61.20
IUUC-Pca-100779	Procavia capensis	60.03	1.00e-166	580.00
IUUC-Ppe-101818	Prunus persica	35.62	5.00e-12	64.30
IUUC-Pva-102839	Pteropus vampyrus	73.22	0.00e+00	707.00
IUUC-Ptt-103859	Puccinia triticina	39.33	4.00e-77	282.00
IUUC-Pte-104241	Pyrenophora teres	31.70	2.00e-61	231.00
IUUC-Pyt-104741	Pyrenophora triticirepentis	33.08	4.00e-61	230.00
IUUC-Rno-105933	Rattus norvegicus	68.56	0.00e+00	1128.00
IUUC-Ssc-115645	Sus scrofa	85.31	0.00e+00	861.00
IUUC-Tru-118403	Takifugu rubripes	71.82	0.00e+00	827.00
IUUC-Tsy-119214	Tarsius syrichta	61.81	0.00e+00	877.00
IUUC-Tni-119736	Tetraodon nigroviridis	75.05	0.00e+00	832.00
IUUC-Tca-121689	Theobroma cacao	34.25	3.00e-11	61.60
IUUC-Tme-127054	Tuber melanosporum	32.27	1.00e-56	215.00
IUUC-Tbe-128138	Tupaia belangeri	88.09	0.00e+00	684.00
IUUC-Vpa-130595	Vicugna pacos	87.37	5.00e-108	385.00
IUUC-Xtr-132307	Xenopus tropicalis	69.08	0.00e+00	1133.00
IUUC-Xma-134323	Xiphophorus maculatus	83.51	0.00e+00	844.00
IUUC-Yli-134626	Yarrowia lipolytica	35.92	3.00e-60	225.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence