iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074113

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02026158

Gene Name

BMI1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000005420.3	ENSOCUT00000005421.3	ENSOCUP00000004703.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.60e-06	27.9	18	57
ULD/UDP/UFD/RAWUL	1.60e-30	105.5	131	226

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C +C   f d + +  C H f+++C+ ++        ++ +CP+C+
   Q: 18   CVLCGGYFIDATTIIECLHSFCKTCIVRY------LETSKYCPICD 57
           ********99999****************......**********5 PP

ULD/UDP/UFD/RAWUL

   S: 1    islsLeplesnkakddsk..........lkkkylrcsarltVkhlkkflaeklklsssyevdllcedevLednetLeeikyifiwkkeg 79
           isls+e++++n+ +++            ++k+ylrc+a++tV+hl+kfl++k+++++++++d+++e+e+L+d++tL++i+yi++w+++g
   Q: 131  ISLSIEFFDQNRLDRKVSkdkekskeevNDKRYLRCPAAMTVMHLRKFLRSKMDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNG 219
           6888888888888776557778888999************************************************************* PP
   S: 80   pLvLqYr 86
           pL+L+Yr
   Q: 220  PLPLKYR 226
           ******9 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MHRTTRIKIT ELNPHLMCVL CGGYFIDATT IIECLHSFCK TCIVRYLETS KYCPICDVQV 60
HKTRPLLNIR SDKTLQDIVY KLVPGLFKNE MKRRRDFYAA HPSADAANGS NEDRGEVADE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCACCCTCTC TACTGTCAGA GTCACGATAT GAAAGAGCTC TTCGCAAGGA GGCGACGTGG 60
GAGAGGCCCC CCATAGCGAC CGAAATGGCC GGGAGTTGTG TTTGCCTCTT CCTCTAGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032443--RAWUL
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF16207--RAWUL

SMART

SM00184--RING

Gene Ontology

GO:0000792--C:heterochromatin
GO:0016604--C:nuclear body
GO:0031519--C:PcG protein complex
GO:0000151--C:ubiquitin ligase complex
GO:1990841--F:promoter-specific chromatin binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0008270--F:zinc ion binding
GO:0007420--P:brain development
GO:0006306--P:DNA methylation
GO:0048704--P:embryonic skeletal system morphogenesis
GO:0016573--P:histone acetylation
GO:0016574--P:histone ubiquitination
GO:0006959--P:humoral immune response
GO:0001701--P:in utero embryonic development
GO:2001234--P:negative regulation of apoptotic signaling pathway
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030890--P:positive regulation of B cell proliferation
GO:0033092--P:positive regulation of immature T cell proliferation in thymus
GO:2000011--P:regulation of adaxial/abaxial pattern formation
GO:0021903--P:rostrocaudal neural tube patterning
GO:0048103--P:somatic stem cell division

KEGG

ocu:100009347

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000603	Aegilops tauschii	37.21	5.00e-12	65.50
IUUC-Aml-001498	Ailuropoda melanoleuca	98.16	8.00e-170	589.00
IUUC-Apl-004208	Anas platyrhynchos	94.44	7.00e-136	476.00
IUUC-Aca-004661	Anolis carolinensis	83.13	7.00e-140	489.00
IUUC-Ath-007649	Arabidopsis thaliana	42.50	3.00e-12	66.60
IUUC-Ame-010610	Astyanax mexicanus	72.95	3.00e-138	484.00
IUUC-Bta-012606	Bos taurus	98.47	8.00e-171	592.00
IUUC-Cja-019482	Callithrix jacchus	99.04	1.00e-180	625.00
IUUC-Cfa-020482	Canis familiaris	98.16	8.00e-170	589.00
IUUC-Cpo-022061	Cavia porcellus	99.04	0.00e+00	626.00
IUUC-Csa-024102	Chlorocebus sabaeus	99.36	0.00e+00	630.00
IUUC-Cho-025081	Choloepus hoffmanni	81.53	5.00e-112	396.00
IUUC-Cin-025612	Ciona intestinalis	49.07	3.00e-52	198.00
IUUC-Dre-027929	Danio rerio	79.45	3.00e-142	497.00
IUUC-Dno-029797	Dasypus novemcinctus	97.45	0.00e+00	641.00
IUUC-Dor-030256	Dipodomys ordii	95.86	5.00e-169	586.00
IUUC-Dme-031904	Drosophila melanogaster	45.02	3.00e-53	204.00
IUUC-Ete-033148	Echinops telfairi	64.71	6.00e-83	300.00
IUUC-Eca-033318	Equus caballus	98.77	3.00e-171	593.00
IUUC-Eeu-034547	Erinaceus europaeus	85.67	2.00e-149	521.00
IUUC-Fca-035866	Felis catus	98.77	9.00e-171	592.00
IUUC-Fal-036660	Ficedula albicollis	95.40	5.00e-161	560.00
IUUC-Gmo-039341	Gadus morhua	82.69	1.00e-125	442.00
IUUC-Gga-040611	Gallus gallus	94.90	3.00e-166	577.00
IUUC-Gac-041888	Gasterosteus aculeatus	72.19	7.00e-129	453.00
IUUC-Gma-042798	Glycine max	39.02	6.00e-12	65.50
IUUC-Ggo-045027	Gorilla gorilla	99.36	0.00e+00	627.00
IUUC-Hsa-045665	Homo sapiens	99.39	0.00e+00	630.00
IUUC-Itr-049045	Ictidomys tridecemlineatus	98.73	2.00e-178	618.00
IUUC-Lch-049714	Latimeria chalumnae	86.54	9.00e-165	572.00
IUUC-Loc-052161	Lepisosteus oculatus	81.04	7.00e-144	503.00
IUUC-Laf-054108	Loxodonta africana	97.17	2.00e-178	617.00
IUUC-Mcc-055562	Macaca mulatta	99.36	0.00e+00	630.00
IUUC-Meu-056709	Macropus eugenii	97.24	2.00e-173	601.00
IUUC-Mtr-058158	Medicago truncatula	43.42	4.00e-10	57.40
IUUC-Mga-060104	Meleagris gallopavo	91.97	2.00e-120	424.00
IUUC-Mmr-061191	Microcebus murinus	99.39	0.00e+00	630.00
IUUC-Mdo-062711	Monodelphis domestica	92.81	3.00e-153	533.00
IUUC-Mmu-064255	Mus musculus	94.59	6.00e-167	579.00
IUUC-Mpu-066466	Mustela putorius furo	97.85	6.00e-170	589.00
IUUC-Mlu-067622	Myotis lucifugus	98.73	4.00e-180	623.00
IUUC-Nle-069253	Nomascus leucogenys	99.36	0.00e+00	630.00
IUUC-Opr-070511	Ochotona princeps	99.04	4.00e-179	620.00
IUUC-Ont-072177	Oreochromis niloticus	84.23	1.00e-129	456.00
IUUC-Oan-073336	Ornithorhynchus anatinus	96.93	7.00e-171	592.00
IUUC-Ola-087057	Oryzias latipes	85.19	4.00e-124	437.00
IUUC-Oga-088346	Otolemur garnettii	99.36	0.00e+00	627.00
IUUC-Oar-089843	Ovis aries	98.47	8.00e-171	592.00
IUUC-Ptr-090486	Pan troglodytes	99.36	0.00e+00	627.00
IUUC-Pan-092667	Papio anubis	99.62	1.00e-159	555.00
IUUC-Psi-093469	Pelodiscus sinensis	94.79	1.00e-172	598.00
IUUC-Pma-094481	Petromyzon marinus	74.04	7.00e-90	322.00
IUUC-Pfo-097156	Poecilia formosa	79.73	2.00e-133	468.00
IUUC-Pab-097670	Pongo abelii	99.36	0.00e+00	627.00
IUUC-Pop-099100	Populus trichocarpa	37.65	1.00e-12	67.40
IUUC-Pva-102800	Pteropus vampyrus	99.36	0.00e+00	627.00
IUUC-Rno-105128	Rattus norvegicus	94.27	3.00e-170	590.00
IUUC-Sha-106747	Sarcophilus harrisii	97.85	3.00e-163	567.00
IUUC-Sar-113416	Sorex araneus	98.73	5.00e-180	623.00
IUUC-Ssc-115864	Sus scrofa	99.04	0.00e+00	626.00
IUUC-Tgu-116851	Taeniopygia guttata	94.44	7.00e-136	476.00
IUUC-Tru-117698	Takifugu rubripes	86.59	6.00e-125	439.00
IUUC-Tsy-119590	Tarsius syrichta	98.73	4.00e-180	623.00
IUUC-Tni-120170	Tetraodon nigroviridis	83.85	1.00e-128	452.00
IUUC-Tae-123760	Triticum aestivum	37.21	6.00e-12	65.50
IUUC-Tur-126396	Triticum urartu	37.21	6.00e-12	65.10
IUUC-Tbe-127790	Tupaia belangeri	99.04	0.00e+00	625.00
IUUC-Ttr-129316	Tursiops truncatus	99.08	5.00e-180	623.00
IUUC-Vpa-130669	Vicugna pacos	99.08	2.00e-171	594.00
IUUC-Xtr-131912	Xenopus tropicalis	87.77	6.00e-148	516.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence