iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-021725

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02007277

Gene Name

ZNRF3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000013801.3	ENSCPOT00000013941.2	ENSCPOP00000012435.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	82.99	0.00e+00	1268.00	IUUC-Hsa-046484

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Cavia porcellus

Protein Sequence
(Fasta)

KGKRWEETSP PPPLPPNRGI PACWRGPKET GAKETAFVEV VLFESSPSGD YTTYTTGLTG 60
RFSPAGATLS AEGEIVQMHP LGLCNNNDEE DLYEYGWVGV VKLEQPELDP KPCLTVLGKA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGGGGAAGC GCTGGGAGGA GACTTCTCCA CCTCCCCCAC TGCCTCCAAA TCGGGGGATC 60
CCAGAGGAGC CAGGGACTCA GGCCAACTTC TCTGCTGTCC TTTGTGATTT GAAGTCACCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:0072089--P:stem cell proliferation
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0038018--P:Wnt receptor catabolic process
GO:0060071--P:Wnt signaling pathway, planar cell polarity pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001916	Ailuropoda melanoleuca	80.02	0.00e+00	1129.00
IUUC-Apl-004188	Anas platyrhynchos	69.42	0.00e+00	980.00
IUUC-Aca-004606	Anolis carolinensis	36.71	1.00e-26	114.00
IUUC-Aly-005850	Arabidopsis lyrata	41.46	3.00e-15	73.90
IUUC-Ath-007372	Arabidopsis thaliana	41.46	2.00e-14	71.60
IUUC-Ame-011764	Astyanax mexicanus	61.04	0.00e+00	698.00
IUUC-Bta-012478	Bos taurus	59.25	6.00e-170	591.00
IUUC-Bdi-014078	Brachypodium distachyon	62.79	9.00e-13	66.60
IUUC-Bol-016217	Brassica oleracea	54.17	3.00e-14	70.50
IUUC-Bra-017407	Brassica rapa	54.17	3.00e-14	70.50
IUUC-Cja-019504	Callithrix jacchus	83.33	0.00e+00	1225.00
IUUC-Cfa-020048	Canis familiaris	82.40	0.00e+00	1218.00
IUUC-Csa-023586	Chlorocebus sabaeus	81.34	0.00e+00	1175.00
IUUC-Cho-024867	Choloepus hoffmanni	86.65	0.00e+00	644.00
IUUC-Cin-025569	Ciona intestinalis	45.27	8.00e-56	211.00
IUUC-Csv-025869	Ciona savignyi	42.96	2.00e-56	213.00
IUUC-Dre-027553	Danio rerio	64.29	0.00e+00	806.00
IUUC-Dno-029370	Dasypus novemcinctus	78.74	0.00e+00	1116.00
IUUC-Dor-030816	Dipodomys ordii	76.07	0.00e+00	1069.00
IUUC-Ete-033060	Echinops telfairi	70.96	0.00e+00	783.00
IUUC-Eca-034044	Equus caballus	84.00	0.00e+00	1233.00
IUUC-Eeu-034591	Erinaceus europaeus	63.98	4.00e-130	458.00
IUUC-Fca-036000	Felis catus	83.27	0.00e+00	1222.00
IUUC-Fal-037147	Ficedula albicollis	67.88	0.00e+00	972.00
IUUC-Gmo-039099	Gadus morhua	47.70	8.00e-112	397.00
IUUC-Gga-041243	Gallus gallus	65.01	0.00e+00	759.00
IUUC-Gac-041340	Gasterosteus aculeatus	47.91	7.00e-107	380.00
IUUC-Gma-044387	Glycine max	48.28	5.00e-15	74.30
IUUC-Ggo-044953	Gorilla gorilla	82.33	0.00e+00	1207.00
IUUC-Hsa-046484	Homo sapiens	83.68	0.00e+00	1276.00
IUUC-Itr-048470	Ictidomys tridecemlineatus	84.26	0.00e+00	1226.00
IUUC-Lch-050004	Latimeria chalumnae	57.46	0.00e+00	643.00
IUUC-Loc-051830	Lepisosteus oculatus	65.16	0.00e+00	798.00
IUUC-Laf-053975	Loxodonta africana	81.75	0.00e+00	1177.00
IUUC-Mcc-055302	Macaca mulatta	81.95	0.00e+00	1162.00
IUUC-Meu-056263	Macropus eugenii	72.35	0.00e+00	761.00
IUUC-Mtr-058744	Medicago truncatula	53.45	4.00e-14	70.90
IUUC-Mga-059706	Meleagris gallopavo	69.04	0.00e+00	1002.00
IUUC-Mmr-061372	Microcebus murinus	79.98	0.00e+00	1149.00
IUUC-Mdo-062651	Monodelphis domestica	62.82	0.00e+00	832.00
IUUC-Mmu-064339	Mus musculus	83.53	0.00e+00	1261.00
IUUC-Mpu-066211	Mustela putorius furo	80.12	0.00e+00	1170.00
IUUC-Mlu-067058	Myotis lucifugus	82.63	0.00e+00	1134.00
IUUC-Nle-069886	Nomascus leucogenys	82.53	0.00e+00	1197.00
IUUC-Opr-070218	Ochotona princeps	75.74	0.00e+00	1019.00
IUUC-Ont-072483	Oreochromis niloticus	60.94	0.00e+00	783.00
IUUC-Oan-073718	Ornithorhynchus anatinus	67.54	0.00e+00	878.00
IUUC-Ocu-073847	Oryctolagus cuniculus	75.51	0.00e+00	985.00
IUUC-Oba-075528	Oryza barthii	43.64	2.00e-12	66.60
IUUC-Ogl-076953	Oryza glaberrima	43.64	2.00e-12	67.00
IUUC-Ome-081485	Oryza meridionalis	53.06	1.00e-11	63.90
IUUC-Oni-082249	Oryza nivara	53.06	1.00e-11	64.30
IUUC-Ola-087358	Oryzias latipes	60.35	0.00e+00	724.00
IUUC-Oga-088362	Otolemur garnettii	81.80	0.00e+00	1218.00
IUUC-Oar-090197	Ovis aries	93.91	1.00e-94	340.00
IUUC-Ptr-091350	Pan troglodytes	83.33	0.00e+00	1274.00
IUUC-Pan-091700	Papio anubis	82.31	0.00e+00	1209.00
IUUC-Psi-093301	Pelodiscus sinensis	68.14	0.00e+00	915.00
IUUC-Pfo-096917	Poecilia formosa	59.51	0.00e+00	727.00
IUUC-Pab-097932	Pongo abelii	81.55	0.00e+00	1211.00
IUUC-Pop-099512	Populus trichocarpa	41.98	2.00e-14	72.40
IUUC-Pca-101054	Procavia capensis	87.54	0.00e+00	910.00
IUUC-Ppe-101375	Prunus persica	48.98	6.00e-13	67.00
IUUC-Pva-102879	Pteropus vampyrus	82.30	0.00e+00	1201.00
IUUC-Pgr-103645	Puccinia graminis	48.84	2.00e-09	55.80
IUUC-Sha-106507	Sarcophilus harrisii	51.19	3.00e-154	538.00
IUUC-Sit-110656	Setaria italica	67.44	3.00e-13	68.20
IUUC-Stu-112289	Solanum tuberosum	38.96	2.00e-13	68.60
IUUC-Sar-113182	Sorex araneus	82.42	4.00e-107	382.00
IUUC-Ssc-115966	Sus scrofa	76.32	0.00e+00	993.00
IUUC-Tgu-116864	Taeniopygia guttata	62.74	1.00e-179	622.00
IUUC-Tru-118502	Takifugu rubripes	60.62	0.00e+00	755.00
IUUC-Tsy-119210	Tarsius syrichta	83.15	0.00e+00	1196.00
IUUC-Tni-120344	Tetraodon nigroviridis	50.09	1.00e-113	403.00
IUUC-Tca-120966	Theobroma cacao	48.44	5.00e-14	72.00
IUUC-Tbe-127735	Tupaia belangeri	80.25	6.00e-123	434.00
IUUC-Ttr-128714	Tursiops truncatus	69.60	0.00e+00	928.00
IUUC-Xtr-132280	Xenopus tropicalis	60.10	0.00e+00	737.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence