iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000010547.3	ENSFCAT00000029335.1	ENSFCAP00000017495.1
ENSFCAG00000010547.3	ENSFCAT00000010550.3	ENSFCAP00000009792.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.70e-11	44.3	34	98

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgklde 67
           +Dv++ v+g++++ah++vLaa+Ss+F++ + ++ +    +l +++ + v  + f+ l++F Yt kl +
   Q: 34   CDVTVLVEGQRYRAHRSVLAACSSYFHSRIVGQADA---ELSITLPEeVTVKGFEPLIQFAYTAKLIL 98
           8*****************************887764...578999966*****************987 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MSLSENAVFA YESSVHSTNV LLGLNDQRKK DVLCDVTVLV EGQRYRAHRS VLAACSSYFH 60
SRIVGQADAE LSITLPEEVT VKGFEPLIQF AYTAKLILSK DNVDEVCKCV EFLGVRDIEE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTCTGCAG GTTTGATGAC GACGAGAAGC ATGCTTTCAC TGGCCTTCCC GACCCCATTT 60
GTTATGCAGA ATGTCTCTGA GTGAGAACGC GGTGTTTGCC TATGAATCTT CGGTGCACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation

Interpro

IPR000210--BTB/POZ_dom
IPR004827--bZIP
IPR004826--bZIP_Maf
IPR011333--SKP1/BTB/POZ
IPR008917--TF_DNA-bd

PROSITE

PS50097--BTB
PS50217--BZIP
PS00036--BZIP_BASIC

Pfam

PF00651--BTB
PF03131--bZIP_Maf

SMART

SM00338--BRLZ
SM00225--BTB

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0000980--F:RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0001205--F:transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001206--F:transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0006281--P:DNA repair
GO:0016567--P:protein ubiquitination
GO:0061418--P:regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0000083--P:regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000117--P:regulation of transcription involved in G2/M transition of mitotic cell cycle
GO:0006366--P:transcription from RNA polymerase II promoter

KEGG

fca:101097412

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002273	Ailuropoda melanoleuca	89.05	0.00e+00	1256.00
IUUC-Apl-003378	Anas platyrhynchos	66.57	0.00e+00	771.00
IUUC-Aca-004992	Anolis carolinensis	56.19	0.00e+00	673.00
IUUC-Ame-011817	Astyanax mexicanus	34.79	3.00e-75	276.00
IUUC-Bta-012599	Bos taurus	81.71	0.00e+00	1169.00
IUUC-Cja-019778	Callithrix jacchus	86.02	0.00e+00	1241.00
IUUC-Cfa-020459	Canis familiaris	90.04	0.00e+00	1308.00
IUUC-Cpo-021433	Cavia porcellus	80.51	0.00e+00	1155.00
IUUC-Csa-023346	Chlorocebus sabaeus	86.15	0.00e+00	1226.00
IUUC-Cho-024893	Choloepus hoffmanni	82.16	0.00e+00	1196.00
IUUC-Dre-027866	Danio rerio	36.77	2.00e-72	266.00
IUUC-Dno-029607	Dasypus novemcinctus	84.31	0.00e+00	1205.00
IUUC-Dor-031026	Dipodomys ordii	61.06	1.00e-142	500.00
IUUC-Ete-032304	Echinops telfairi	73.07	0.00e+00	999.00
IUUC-Eca-033379	Equus caballus	83.84	0.00e+00	987.00
IUUC-Eeu-035358	Erinaceus europaeus	83.11	0.00e+00	937.00
IUUC-Fal-037171	Ficedula albicollis	64.36	0.00e+00	711.00
IUUC-Gga-041169	Gallus gallus	62.53	0.00e+00	816.00
IUUC-Gma-043627	Glycine max	30.21	3.00e-07	49.70
IUUC-Ggo-044485	Gorilla gorilla	85.62	0.00e+00	1234.00
IUUC-Hsa-046202	Homo sapiens	86.15	0.00e+00	1219.00
IUUC-Itr-047970	Ictidomys tridecemlineatus	85.07	0.00e+00	1245.00
IUUC-Loc-052298	Lepisosteus oculatus	45.56	6.00e-59	222.00
IUUC-Laf-054320	Loxodonta africana	82.34	0.00e+00	954.00
IUUC-Mcc-055644	Macaca mulatta	86.55	0.00e+00	1229.00
IUUC-Mga-059196	Meleagris gallopavo	60.75	0.00e+00	801.00
IUUC-Mmr-061053	Microcebus murinus	86.68	0.00e+00	1258.00
IUUC-Mdo-062091	Monodelphis domestica	60.24	0.00e+00	739.00
IUUC-Mmu-063403	Mus musculus	77.88	0.00e+00	1103.00
IUUC-Mpu-065768	Mustela putorius furo	90.28	0.00e+00	1269.00
IUUC-Mlu-067451	Myotis lucifugus	76.70	0.00e+00	1013.00
IUUC-Nle-069507	Nomascus leucogenys	86.28	0.00e+00	1243.00
IUUC-Oan-073692	Ornithorhynchus anatinus	66.15	2.00e-99	356.00
IUUC-Ocu-074850	Oryctolagus cuniculus	90.57	0.00e+00	1161.00
IUUC-Oga-088762	Otolemur garnettii	84.57	0.00e+00	1240.00
IUUC-Oar-089511	Ovis aries	85.08	0.00e+00	1068.00
IUUC-Ptr-091232	Pan troglodytes	86.02	0.00e+00	1258.00
IUUC-Pan-091803	Papio anubis	86.42	0.00e+00	1226.00
IUUC-Pab-098303	Pongo abelii	86.02	0.00e+00	1235.00
IUUC-Pca-100147	Procavia capensis	74.67	0.00e+00	713.00
IUUC-Pva-102920	Pteropus vampyrus	86.42	0.00e+00	1261.00
IUUC-Rno-105893	Rattus norvegicus	76.82	0.00e+00	1086.00
IUUC-Sha-107059	Sarcophilus harrisii	67.90	0.00e+00	895.00
IUUC-Sar-113133	Sorex araneus	83.85	3.00e-179	622.00
IUUC-Ssc-115328	Sus scrofa	85.58	0.00e+00	1163.00
IUUC-Tgu-116625	Taeniopygia guttata	63.10	0.00e+00	828.00
IUUC-Tru-118149	Takifugu rubripes	38.29	4.00e-43	169.00
IUUC-Tni-120068	Tetraodon nigroviridis	57.69	3.00e-38	153.00
IUUC-Ttr-128805	Tursiops truncatus	88.28	0.00e+00	887.00
IUUC-Xtr-132494	Xenopus tropicalis	47.67	1.00e-166	580.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence