iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033810

Ensembl Protein ID

ENSECAP00000015239.1

UniProt Accession

F6QMU5; F6QMU5_HORSE

Protein Name

Uncharacterized protein

Gene Name

CRKL

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000017629.1	ENSECAT00000018670.1	ENSECAP00000015239.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.80e-19	69.6	124	181

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           ++e+v++lyd+ +++ ++L +kkG+++ +i  e+ +e W+++ ++  g+ G++P  +vekl
   Q: 124  NLEYVRTLYDFPGNDAEDLPFKKGEILVII--EKPEEQWWSA-RNKDGRVGMIPVPYVEKL 181
           5789**************************..88999***99.6**************997 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MSSARFDSSD RSAWYMGPVS RQEAQTRLQG QRHGMFLVRD SSTCPGDYVL SVSENSRVSH 60
YIINSLPNRR FKIGDQEFDH LPALLEFYKI HYLDTTTLIE PAPRYPSPPM GSVSAPSLPT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCCGCAGG GCTCCGGTCC GACACCATGT CCTCCGCCAG GTTCGACTCC TCAGACCGCT 60
CCGCCTGGTA CATGGGGCCG GTGTCGCGCC AGGAGGCGCA GACCCGGCTC CAAGGCCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0003723--F:RNA binding
GO:0009887--P:animal organ morphogenesis
GO:0009952--P:anterior/posterior pattern specification
GO:0001568--P:blood vessel development
GO:0007507--P:heart development
GO:0060017--P:parathyroid gland development
GO:0008284--P:positive regulation of cell proliferation
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:0048538--P:thymus development

KEGG

ecb:100050855

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002025	Ailuropoda melanoleuca	98.97	1.00e-173	601.00
IUUC-Apl-004166	Anas platyrhynchos	89.74	7.00e-159	552.00
IUUC-Aca-004695	Anolis carolinensis	53.22	4.00e-84	303.00
IUUC-Ame-011285	Astyanax mexicanus	80.46	4.00e-140	490.00
IUUC-Bta-013076	Bos taurus	80.74	2.00e-113	401.00
IUUC-Cja-019850	Callithrix jacchus	98.62	3.00e-172	597.00
IUUC-Cfa-020428	Canis familiaris	98.28	4.00e-172	596.00
IUUC-Cpo-022079	Cavia porcellus	97.59	5.00e-171	593.00
IUUC-Csa-023877	Chlorocebus sabaeus	97.59	4.00e-171	593.00
IUUC-Cin-025128	Ciona intestinalis	51.71	3.00e-81	294.00
IUUC-Csv-026340	Ciona savignyi	47.93	1.00e-70	259.00
IUUC-Dre-027833	Danio rerio	81.69	5.00e-136	476.00
IUUC-Dno-029510	Dasypus novemcinctus	95.86	2.00e-169	587.00
IUUC-Dor-030297	Dipodomys ordii	98.02	3.00e-177	613.00
IUUC-Dme-031600	Drosophila melanogaster	43.52	5.00e-69	253.00
IUUC-Fca-036412	Felis catus	98.97	1.00e-173	601.00
IUUC-Fal-037170	Ficedula albicollis	91.38	2.00e-153	535.00
IUUC-Gga-040733	Gallus gallus	92.41	3.00e-142	497.00
IUUC-Gac-042398	Gasterosteus aculeatus	80.77	1.00e-144	505.00
IUUC-Ggo-044447	Gorilla gorilla	96.98	1.00e-113	401.00
IUUC-Hsa-046989	Homo sapiens	97.93	3.00e-171	593.00
IUUC-Itr-048092	Ictidomys tridecemlineatus	98.97	6.00e-173	599.00
IUUC-Kpa-049154	Komagataella pastoris	40.91	2.00e-10	60.10
IUUC-Lch-050385	Latimeria chalumnae	60.20	8.00e-100	356.00
IUUC-Loc-052916	Lepisosteus oculatus	86.56	1.00e-149	521.00
IUUC-Laf-053545	Loxodonta africana	99.00	5.00e-116	409.00
IUUC-Mga-059586	Meleagris gallopavo	93.79	9.00e-156	542.00
IUUC-Mvi-060518	Microbotryum violaceum	37.70	7.00e-11	61.20
IUUC-Mdo-061868	Monodelphis domestica	90.00	3.00e-159	553.00
IUUC-Mmu-063179	Mus musculus	96.90	7.00e-171	592.00
IUUC-Mpu-065863	Mustela putorius furo	98.97	2.00e-173	600.00
IUUC-Mlu-067290	Myotis lucifugus	97.24	1.00e-170	591.00
IUUC-Nle-069118	Nomascus leucogenys	97.93	3.00e-171	593.00
IUUC-Opr-070565	Ochotona princeps	96.37	3.00e-175	607.00
IUUC-Ont-071608	Oreochromis niloticus	82.11	1.00e-148	518.00
IUUC-Oan-072801	Ornithorhynchus anatinus	89.44	4.00e-163	566.00
IUUC-Ocu-073759	Oryctolagus cuniculus	98.28	3.00e-172	597.00
IUUC-Ola-086748	Oryzias latipes	75.99	2.00e-125	441.00
IUUC-Oga-088248	Otolemur garnettii	98.28	6.00e-172	596.00
IUUC-Oar-089525	Ovis aries	77.13	1.00e-123	435.00
IUUC-Ptr-091553	Pan troglodytes	97.93	3.00e-171	593.00
IUUC-Pan-092639	Papio anubis	97.93	3.00e-171	593.00
IUUC-Psi-093546	Pelodiscus sinensis	87.73	3.00e-102	363.00
IUUC-Pma-094340	Petromyzon marinus	60.32	7.00e-105	373.00
IUUC-Pfo-096090	Poecilia formosa	82.35	6.00e-148	516.00
IUUC-Pab-097876	Pongo abelii	97.42	2.00e-135	474.00
IUUC-Pca-100447	Procavia capensis	98.62	6.00e-173	599.00
IUUC-Pva-102346	Pteropus vampyrus	98.27	3.00e-171	593.00
IUUC-Rno-106017	Rattus norvegicus	96.90	2.00e-170	590.00
IUUC-Sha-106511	Sarcophilus harrisii	90.21	1.00e-103	368.00
IUUC-Sar-113583	Sorex araneus	96.55	2.00e-169	587.00
IUUC-Sre-115190	Sporisorium reilianum	29.67	2.00e-09	58.50
IUUC-Ssc-115339	Sus scrofa	96.55	6.00e-169	586.00
IUUC-Tgu-116454	Taeniopygia guttata	91.21	4.00e-98	350.00
IUUC-Tru-118580	Takifugu rubripes	78.46	2.00e-139	488.00
IUUC-Tsy-119327	Tarsius syrichta	96.56	5.00e-168	583.00
IUUC-Tni-120626	Tetraodon nigroviridis	78.21	2.00e-139	488.00
IUUC-Ttr-128248	Tursiops truncatus	98.28	2.00e-172	597.00
IUUC-Xtr-132626	Xenopus tropicalis	87.79	4.00e-154	536.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence