iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000016139.1	ENSLACT00000018454.1	ENSLACP00000018321.1
ENSLACG00000016139.1	ENSLACT00000018455.1	ENSLACP00000018322.1
ENSLACG00000016139.1	ENSLACT00000018456.1	ENSLACP00000018323.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	7.20e-12	45.3	712	764

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           k ++ly  +a++d eL++ +G v + + + +q+ gWl+g  +l g+ Gl+Pen+ve
   Q: 712  KAKALYACKAEHDSELSFSAGTVFENV-HPSQEPGWLEG--TLDGRTGLIPENYVE 764
           789************************.***********..8*************8 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

DLSLAKRKFA ESLNEFKFQC IGDAETDDEI CIAKSLQEFA GVLKNLEDER VRMIENASEV 60
LITPLEKFRK EQIGAAKDAK KKYDKETEKY CTVLEKHLSL SSKKKESHLH EADSQVDLVR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGTGCAATC TATTACAAGA TTATCTAATA GGCTAGATTG AGTGTTCAGG GTTTTTTTTT 60
TTTTTAATTT TGTAAGACTG ATAGGAAAAA CTTCAACTAG GGCAATAAAA ATATATAGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0343--GTPase activation
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR030061--RHG26
IPR008936--Rho_GTPase_activation_prot
IPR000198--RhoGAP_dom
IPR001452--SH3_domain

PROSITE

PS50003--PH_DOMAIN
PS50238--RHOGAP
PS50002--SH3

Pfam

PF00169--PH
PF00620--RhoGAP
PF14604--SH3_9

SMART

SM00233--PH
SM00324--RhoGAP
SM00326--SH3

Gene Ontology

GO:0005096--F:GTPase activator activity
GO:0030036--P:actin cytoskeleton organization
GO:0051056--P:regulation of small GTPase mediated signal transduction
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001613	Ailuropoda melanoleuca	81.09	0.00e+00	938.00
IUUC-Apl-003321	Anas platyrhynchos	74.58	0.00e+00	1000.00
IUUC-Aca-004570	Anolis carolinensis	79.45	0.00e+00	964.00
IUUC-Ame-011422	Astyanax mexicanus	76.15	0.00e+00	872.00
IUUC-Bta-013262	Bos taurus	80.76	0.00e+00	938.00
IUUC-Cel-018542	Caenorhabditis elegans	43.28	2.00e-115	410.00
IUUC-Cja-019208	Callithrix jacchus	83.57	0.00e+00	930.00
IUUC-Cfa-020928	Canis familiaris	80.92	0.00e+00	939.00
IUUC-Cpo-021338	Cavia porcellus	75.22	0.00e+00	1025.00
IUUC-Csa-023570	Chlorocebus sabaeus	83.57	0.00e+00	930.00
IUUC-Cin-025725	Ciona intestinalis	43.61	9.00e-114	404.00
IUUC-Cme-027331	Cyanidioschyzon merolae	37.50	2.10e-01	29.60
IUUC-Dre-027525	Danio rerio	61.69	4.00e-179	621.00
IUUC-Dno-029143	Dasypus novemcinctus	75.70	0.00e+00	1025.00
IUUC-Dor-030697	Dipodomys ordii	83.22	0.00e+00	923.00
IUUC-Dme-032147	Drosophila melanogaster	42.63	2.00e-121	430.00
IUUC-Ete-032645	Echinops telfairi	75.00	0.00e+00	808.00
IUUC-Eca-033791	Equus caballus	76.45	0.00e+00	1027.00
IUUC-Eeu-035202	Erinaceus europaeus	59.48	3.00e-97	349.00
IUUC-Fca-036131	Felis catus	76.41	0.00e+00	1033.00
IUUC-Fal-037129	Ficedula albicollis	80.23	0.00e+00	924.00
IUUC-Gga-041023	Gallus gallus	80.69	0.00e+00	956.00
IUUC-Gac-041728	Gasterosteus aculeatus	55.85	3.00e-165	575.00
IUUC-Ggo-044863	Gorilla gorilla	83.27	0.00e+00	924.00
IUUC-Hsa-046471	Homo sapiens	83.75	0.00e+00	931.00
IUUC-Itr-049060	Ictidomys tridecemlineatus	83.22	0.00e+00	951.00
IUUC-Loc-052782	Lepisosteus oculatus	79.80	0.00e+00	980.00
IUUC-Laf-053585	Loxodonta africana	75.55	0.00e+00	1013.00
IUUC-Mcc-055458	Macaca mulatta	83.45	0.00e+00	932.00
IUUC-Meu-056107	Macropus eugenii	67.22	0.00e+00	743.00
IUUC-Mga-059914	Meleagris gallopavo	79.21	0.00e+00	926.00
IUUC-Mmr-060728	Microcebus murinus	75.84	0.00e+00	1017.00
IUUC-Mdo-062387	Monodelphis domestica	77.14	0.00e+00	1082.00
IUUC-Mmu-063756	Mus musculus	82.86	0.00e+00	929.00
IUUC-Mlu-067375	Myotis lucifugus	63.06	0.00e+00	694.00
IUUC-Nle-069043	Nomascus leucogenys	77.96	0.00e+00	740.00
IUUC-Opr-071168	Ochotona princeps	67.49	0.00e+00	723.00
IUUC-Ont-072338	Oreochromis niloticus	78.75	0.00e+00	887.00
IUUC-Oan-073441	Ornithorhynchus anatinus	79.43	0.00e+00	847.00
IUUC-Ocu-073915	Oryctolagus cuniculus	82.86	0.00e+00	949.00
IUUC-Ola-086319	Oryzias latipes	73.08	0.00e+00	850.00
IUUC-Oga-088922	Otolemur garnettii	69.41	2.00e-67	249.00
IUUC-Oar-089349	Ovis aries	80.13	0.00e+00	931.00
IUUC-Ptr-091027	Pan troglodytes	83.57	0.00e+00	927.00
IUUC-Pan-092791	Papio anubis	83.57	0.00e+00	930.00
IUUC-Psi-093144	Pelodiscus sinensis	82.49	0.00e+00	989.00
IUUC-Pma-094731	Petromyzon marinus	27.81	1.00e-17	86.30
IUUC-Pfo-097265	Poecilia formosa	59.79	0.00e+00	641.00
IUUC-Pab-097783	Pongo abelii	83.39	0.00e+00	927.00
IUUC-Pva-102980	Pteropus vampyrus	75.64	0.00e+00	1057.00
IUUC-Rno-105142	Rattus norvegicus	79.24	0.00e+00	939.00
IUUC-Sha-107213	Sarcophilus harrisii	81.09	0.00e+00	971.00
IUUC-Ssc-115511	Sus scrofa	62.63	7.00e-106	377.00
IUUC-Tgu-117313	Taeniopygia guttata	72.80	3.00e-166	578.00
IUUC-Tru-117767	Takifugu rubripes	75.29	0.00e+00	906.00
IUUC-Tsy-119150	Tarsius syrichta	74.11	0.00e+00	1018.00
IUUC-Tni-119893	Tetraodon nigroviridis	72.81	0.00e+00	687.00
IUUC-Tbe-128126	Tupaia belangeri	26.04	3.00e-06	47.00
IUUC-Ttr-129028	Tursiops truncatus	66.03	0.00e+00	830.00
IUUC-Xtr-131767	Xenopus tropicalis	77.65	0.00e+00	897.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence