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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Ath-006812
UUCD1 version UUC-ArT-00782
Ensembl Protein ID AT2G18760.6
UniProt Accession Q9ZV43; CHR8_ARATH
Genbank Protein ID AAD08945.1; AEC06805.1; ANM61954.1; ANM61955.1; ANM61956.1; ANM61957.1; ANM61958.1
Protein Name Protein CHROMATIN REMODELING 8
Genbank Nucleotide ID AC005724; CP002685; CP002685; CP002685; CP002685; CP002685; CP002685
Gene Name CHR8; CSB; ERCC6; RAD26; RAD54; At2g18760; MSF3.14
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT2G18760 AT2G18760.3 AT2G18760.3
AT2G18760 AT2G18760.6 AT2G18760.6
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
Protein-protein Interaction
Mentha
Protein Expression/Proteomics
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/CUE 52.44 2.00e-180 630.00 IUUC-Hsa-046895
UBD/Alpha-Helix/UBA 52.44 2.00e-180 630.00 IUUC-Hsa-046895
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Arabidopsis thaliana
Functional Description
(View)

Functional Description


     Essential factor involved in transcription-coupled nucleotide excision repair (TCR) which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation.
 Essential factor involved in transcription-coupled nucleotide excision repair (TCR) which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation.
Protein Sequence
(Fasta)
MEEDEDQFLL SSLGVTSANP EDLEQKILDE ATKKPDNDEG GSVEEKSTQL EGTNLLSSSQ 60
NELLNKLRAV KFEIDAVAST VENVDEIAAE KGLKKDDESD LQGLHSGSAL QHALATDRLR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ath-006812|UBD,CUE;UBD,UBA|Arabidopsis thaliana
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CAACAATTCT TTCATCTTTG ACGAAACCAG TTTCGCCCAT CGCCGAGCAG TGAGTTTTAA 60
AATTTCTGAC CTAAAAATTC TCATGGGGTT TTATGATTCC TAGTCGATTT TATCTGGAAT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ath-006812|UBD,CUE;UBD,UBA|Arabidopsis thaliana
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0238--DNA-binding
KW-0347--Helicase
KW-0378--Hydrolase
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
Interpro

IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR000330--SNF2_N
PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
Pfam

PF00271--Helicase_C
PF00176--SNF2_N
SMART

SM00487--DEXDc
SM00490--HELICc
Gene Ontology

GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0004386--F:helicase activity
GO:0006974--P:cellular response to DNA damage stimulus
GO:0006281--P:DNA repair
GO:0006355--P:regulation of transcription, DNA-templated
GO:0010332--P:response to gamma radiation
GO:0006351--P:transcription, DNA-templated
KEGG ath:AT2G18760
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000518 Aegilops tauschii 58.36 0.00e+00 1333.00
IUUC-Aml-002021 Ailuropoda melanoleuca 53.00 0.00e+00 628.00
IUUC-Atr-002868 Amborella trichopoda 59.79 0.00e+00 1308.00
IUUC-Apl-003989 Anas platyrhynchos 51.86 0.00e+00 634.00
IUUC-Aca-004609 Anolis carolinensis 52.17 3.00e-180 625.00
IUUC-Aly-005912 Arabidopsis lyrata 94.36 0.00e+00 2085.00
IUUC-Ago-007719 Ashbya gossypii 42.43 0.00e+00 630.00
IUUC-Acl-008050 Aspergillus clavatus 42.74 0.00e+00 644.00
IUUC-Afl-008677 Aspergillus flavus 44.84 4.00e-180 624.00
IUUC-Afu-008975 Aspergillus fumigatus 43.91 0.00e+00 654.00
IUUC-Ani-009464 Aspergillus nidulans 43.38 0.00e+00 658.00
IUUC-Ang-009516 Aspergillus niger 48.14 3.00e-168 585.00
IUUC-Aor-010057 Aspergillus oryzae 44.02 9.00e-180 623.00
IUUC-Ate-010307 Aspergillus terreus 43.76 4.00e-179 621.00
IUUC-Ame-011055 Astyanax mexicanus 50.50 3.00e-180 625.00
IUUC-Bgr-012211 Blumeria graminis 41.82 3.00e-174 605.00
IUUC-Bta-012761 Bos taurus 48.08 4.00e-160 558.00
IUUC-Bci-013603 Botrytis cinerea 45.08 0.00e+00 681.00
IUUC-Bdi-014031 Brachypodium distachyon 60.95 0.00e+00 1398.00
IUUC-Bol-015096 Brassica oleracea 84.37 0.00e+00 1904.00
IUUC-Bra-017583 Brassica rapa 84.38 0.00e+00 1867.00
IUUC-Cel-018275 Caenorhabditis elegans 34.40 7.00e-90 325.00
IUUC-Cja-019733 Callithrix jacchus 52.91 0.00e+00 629.00
IUUC-Cfa-020631 Canis familiaris 53.82 0.00e+00 633.00
IUUC-Cpo-022218 Cavia porcellus 53.32 2.00e-180 626.00
IUUC-Cre-022710 Chlamydomonas reinhardtii 56.13 2.00e-180 626.00
IUUC-Csa-023723 Chlorocebus sabaeus 52.91 0.00e+00 629.00
IUUC-Cho-024312 Choloepus hoffmanni 49.61 4.00e-75 276.00
IUUC-Cin-025376 Ciona intestinalis 50.62 2.00e-165 575.00
IUUC-Cgl-026654 Colletotrichum gloeosporioides 46.89 3.00e-163 568.00
IUUC-Cme-027109 Cyanidioschyzon merolae 42.86 1.00e-152 533.00
IUUC-Dre-028672 Danio rerio 49.21 0.00e+00 637.00
IUUC-Dno-028893 Dasypus novemcinctus 53.62 0.00e+00 634.00
IUUC-Dor-031114 Dipodomys ordii 49.15 5.00e-113 402.00
IUUC-Dse-031225 Dothistroma septosporum 47.90 1.00e-180 627.00
IUUC-Ete-032713 Echinops telfairi 57.51 2.00e-77 283.00
IUUC-Eca-034071 Equus caballus 53.32 5.00e-180 625.00
IUUC-Eeu-034781 Erinaceus europaeus 52.38 2.00e-178 619.00
IUUC-Fca-036561 Felis catus 52.39 1.00e-177 617.00
IUUC-Fal-037343 Ficedula albicollis 51.31 1.00e-179 624.00
IUUC-Fox-037667 Fusarium oxysporum 46.99 2.00e-164 572.00
IUUC-Fso-038331 Fusarium solani 46.92 2.00e-165 575.00
IUUC-Gmo-039132 Gadus morhua 52.76 1.00e-176 613.00
IUUC-Gga-040376 Gallus gallus 52.03 0.00e+00 634.00
IUUC-Gac-042326 Gasterosteus aculeatus 50.87 3.00e-176 612.00
IUUC-Gma-043401 Glycine max 64.94 0.00e+00 1433.00
IUUC-Ggo-044844 Gorilla gorilla 53.09 0.00e+00 629.00
IUUC-Hsa-046895 Homo sapiens 52.91 0.00e+00 628.00
IUUC-Itr-048071 Ictidomys tridecemlineatus 47.32 7.00e-180 624.00
IUUC-Kpa-049261 Komagataella pastoris 50.29 0.00e+00 684.00
IUUC-Lch-049934 Latimeria chalumnae 52.03 8.00e-175 607.00
IUUC-Lpe-051249 Leersia perrieri 61.41 0.00e+00 979.00
IUUC-Loc-052591 Lepisosteus oculatus 51.68 6.00e-178 618.00
IUUC-Lma-053210 Leptosphaeria maculans 46.42 0.00e+00 631.00
IUUC-Laf-054403 Loxodonta africana 54.06 0.00e+00 634.00
IUUC-Mcc-054876 Macaca mulatta 52.91 0.00e+00 629.00
IUUC-Meu-056545 Macropus eugenii 64.57 8.00e-46 178.00
IUUC-Mor-057145 Magnaporthe oryzae 45.17 1.00e-172 600.00
IUUC-Mpo-057493 Magnaporthe poae 47.46 3.00e-168 585.00
IUUC-Mtr-057734 Medicago truncatula 63.76 0.00e+00 1410.00
IUUC-Mga-059402 Meleagris gallopavo 51.96 0.00e+00 632.00
IUUC-Mmr-061791 Microcebus murinus 52.64 0.00e+00 628.00
IUUC-Mdo-062148 Monodelphis domestica 52.29 0.00e+00 633.00
IUUC-Mmu-063238 Mus musculus 51.99 0.00e+00 628.00
IUUC-Mac-064440 Musa acuminata 60.27 0.00e+00 1227.00
IUUC-Mpu-066112 Mustela putorius furo 53.18 1.00e-180 626.00
IUUC-Mlu-067057 Myotis lucifugus 53.19 2.00e-180 626.00
IUUC-Nfi-068617 Neosartorya fischeri 43.79 0.00e+00 649.00
IUUC-Ncr-068920 Neurospora crassa 45.83 5.00e-175 607.00
IUUC-Nle-069992 Nomascus leucogenys 53.09 0.00e+00 629.00
IUUC-Opr-070929 Ochotona princeps 51.72 1.00e-174 607.00
IUUC-Ont-071740 Oreochromis niloticus 51.29 4.00e-180 625.00
IUUC-Oan-073380 Ornithorhynchus anatinus 53.03 1.00e-134 472.00
IUUC-Ocu-074143 Oryctolagus cuniculus 52.56 4.00e-177 615.00
IUUC-Oba-075626 Oryza barthii 61.98 0.00e+00 1405.00
IUUC-Obr-076240 Oryza brachyantha 62.35 0.00e+00 1384.00
IUUC-Ogl-077187 Oryza glaberrima 62.22 0.00e+00 1397.00
IUUC-Ogu-078629 Oryza glumaepatula 62.46 0.00e+00 1000.00
IUUC-Oin-079268 Oryza indica 61.96 0.00e+00 1399.00
IUUC-Olo-080567 Oryza longistaminata 62.24 0.00e+00 992.00
IUUC-Oni-082122 Oryza nivara 62.13 0.00e+00 1404.00
IUUC-Opu-083477 Oryza punctata 62.74 0.00e+00 1431.00
IUUC-Oru-084783 Oryza rufipogon 62.05 0.00e+00 1405.00
IUUC-Osa-086206 Oryza sativa 67.92 0.00e+00 1209.00
IUUC-Oga-088414 Otolemur garnettii 50.89 7.00e-170 591.00
IUUC-Oar-089697 Ovis aries 53.15 0.00e+00 631.00
IUUC-Ptr-090856 Pan troglodytes 52.91 0.00e+00 628.00
IUUC-Pan-092521 Papio anubis 52.91 0.00e+00 629.00
IUUC-Psi-093037 Pelodiscus sinensis 52.22 0.00e+00 632.00
IUUC-Pma-094456 Petromyzon marinus 49.20 8.00e-158 550.00
IUUC-Pno-094861 Phaeosphaeria nodorum 41.38 3.00e-175 608.00
IUUC-Ppa-095711 Physcomitrella patens 51.86 0.00e+00 1168.00
IUUC-Pfo-096223 Poecilia formosa 50.60 2.00e-178 619.00
IUUC-Pab-098595 Pongo abelii 52.73 4.00e-180 625.00
IUUC-Pop-099531 Populus trichocarpa 66.18 0.00e+00 1471.00
IUUC-Pca-100770 Procavia capensis 57.14 4.00e-100 359.00
IUUC-Ppe-101528 Prunus persica 67.24 0.00e+00 1457.00
IUUC-Pva-102247 Pteropus vampyrus 52.54 7.00e-103 368.00
IUUC-Pte-104217 Pyrenophora teres 46.10 0.00e+00 629.00
IUUC-Pyt-104797 Pyrenophora triticirepentis 46.10 0.00e+00 629.00
IUUC-Rno-105742 Rattus norvegicus 51.82 1.00e-179 623.00
IUUC-Sce-106234 Saccharomyces cerevisiae 43.53 0.00e+00 664.00
IUUC-Sha-106622 Sarcophilus harrisii 48.83 4.00e-164 572.00
IUUC-Sja-107874 Schizosaccharomyces japonicus 47.76 0.00e+00 645.00
IUUC-Spo-108021 Schizosaccharomyces pombe 51.04 0.00e+00 655.00
IUUC-Ssl-108500 Sclerotinia sclerotiorum 49.35 0.00e+00 664.00
IUUC-Smo-109132 Selaginella moellendorffii 54.65 0.00e+00 957.00
IUUC-Sit-110066 Setaria italica 62.85 0.00e+00 1439.00
IUUC-Sly-111833 Solanum lycopersicum 63.10 0.00e+00 1366.00
IUUC-Stu-112189 Solanum tuberosum 64.23 0.00e+00 1368.00
IUUC-Sar-113511 Sorex araneus 51.95 3.00e-156 545.00
IUUC-Sbi-114606 Sorghum bicolor 63.14 0.00e+00 1457.00
IUUC-Ssc-116374 Sus scrofa 53.09 0.00e+00 629.00
IUUC-Tgu-117153 Taeniopygia guttata 50.26 6.00e-180 624.00
IUUC-Tru-118178 Takifugu rubripes 51.80 0.00e+00 627.00
IUUC-Tsy-119524 Tarsius syrichta 50.16 8.00e-175 607.00
IUUC-Tni-120546 Tetraodon nigroviridis 51.95 2.00e-179 623.00
IUUC-Tca-121065 Theobroma cacao 67.20 0.00e+00 1426.00
IUUC-Tre-121868 Trichoderma reesei 47.08 1.00e-165 577.00
IUUC-Tvi-122455 Trichoderma virens 46.64 1.00e-162 566.00
IUUC-Tae-123249 Triticum aestivum 70.10 0.00e+00 1187.00
IUUC-Tur-126107 Triticum urartu 59.81 0.00e+00 1355.00
IUUC-Tbe-127967 Tupaia belangeri 47.86 2.00e-74 273.00
IUUC-Ttr-128768 Tursiops truncatus 52.56 1.00e-176 613.00
IUUC-Vda-129884 Verticillium dahliae 40.91 2.00e-175 609.00
IUUC-Vpa-130521 Vicugna pacos 50.34 2.00e-87 317.00
IUUC-Vvi-130838 Vitis vinifera 66.23 0.00e+00 1446.00
IUUC-Xtr-132056 Xenopus tropicalis 48.23 1.00e-150 526.00
IUUC-Xma-133113 Xiphophorus maculatus 49.34 7.00e-179 620.00
IUUC-Yli-134344 Yarrowia lipolytica 51.98 0.00e+00 657.00
IUUC-Zma-134837 Zea mays 62.91 0.00e+00 1413.00
Created Date 25-Jun-2017

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