iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	miRTarBase	microRNA	TRANSFAC
RepTar	RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.80e-15	57.1	36	102
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	3.20e-07	29.6	137	166

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvg.geeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +D++l++  g  f++h++vLaa+S +F+a+f+ +++e+  k++++++++ ++ ++ l+++ Yt+++++
   Q: 36   TDITLQCPsGIIFHCHRAVLAACSNYFKAMFTADMKEKF-KSKIKLSGIHHDILEGLVNYAYTSQIEI 102
           6999*9999*****************************9.************************9976 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhF 31
           +Nc+g+ +fA+ + c++L +  ++ +++ F
   Q: 137  DNCIGMHSFAEFHVCSELEKESRRILCSRF 166
           8******************99988777666 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MALKGQEDYI FHFKDSSHPV DFLDAFRTFY MDGLFTDITL QCPSGIIFHC HRAVLAACSN 60
YFKAMFTADM KEKFKSKIKL SGIHHDILEG LVNYAYTSQI EITKRNVQSL LEAADLLQFL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGAAGTGG GGGTAGAAAC CCAAGTTGGC TTCCTGGTTG TTCTGGTGCA ATTTCAACAC 60
AGGTTGTGGC TTGGCTTTCG GCGCTTAGGA GTTTCAGCGT TCTCCCATCA TGTAAGGTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

KEGG

mmu:277396

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001639	Ailuropoda melanoleuca	96.78	0.00e+00	1137.00
IUUC-Apl-003948	Anas platyrhynchos	77.65	0.00e+00	857.00
IUUC-Aca-005045	Anolis carolinensis	76.88	0.00e+00	930.00
IUUC-Ame-011013	Astyanax mexicanus	62.92	0.00e+00	768.00
IUUC-Bta-013159	Bos taurus	96.78	0.00e+00	1138.00
IUUC-Cja-018886	Callithrix jacchus	96.42	0.00e+00	1136.00
IUUC-Cfa-020205	Canis familiaris	96.95	0.00e+00	1141.00
IUUC-Cpo-022295	Cavia porcellus	95.70	0.00e+00	1122.00
IUUC-Cho-025089	Choloepus hoffmanni	95.82	0.00e+00	920.00
IUUC-Dre-027681	Danio rerio	60.71	0.00e+00	745.00
IUUC-Dno-029078	Dasypus novemcinctus	95.60	0.00e+00	917.00
IUUC-Ete-033011	Echinops telfairi	85.33	0.00e+00	961.00
IUUC-Eca-033213	Equus caballus	97.13	0.00e+00	1143.00
IUUC-Fca-035884	Felis catus	96.95	0.00e+00	1144.00
IUUC-Fal-036897	Ficedula albicollis	77.08	0.00e+00	922.00
IUUC-Gmo-038594	Gadus morhua	57.37	0.00e+00	702.00
IUUC-Gga-040791	Gallus gallus	75.63	0.00e+00	926.00
IUUC-Gac-042512	Gasterosteus aculeatus	60.14	0.00e+00	739.00
IUUC-Ggo-044837	Gorilla gorilla	96.77	0.00e+00	1136.00
IUUC-Hsa-046231	Homo sapiens	97.13	0.00e+00	1141.00
IUUC-Itr-048084	Ictidomys tridecemlineatus	97.67	0.00e+00	1144.00
IUUC-Lch-050412	Latimeria chalumnae	72.60	0.00e+00	894.00
IUUC-Loc-052033	Lepisosteus oculatus	67.55	0.00e+00	824.00
IUUC-Laf-053908	Loxodonta africana	96.95	0.00e+00	1140.00
IUUC-Mcc-054734	Macaca mulatta	96.95	0.00e+00	1140.00
IUUC-Meu-055982	Macropus eugenii	88.53	0.00e+00	1055.00
IUUC-Mga-059670	Meleagris gallopavo	74.96	0.00e+00	913.00
IUUC-Mmr-060692	Microcebus murinus	97.31	0.00e+00	1143.00
IUUC-Mdo-062419	Monodelphis domestica	89.07	0.00e+00	1061.00
IUUC-Mpu-066515	Mustela putorius furo	96.77	0.00e+00	1140.00
IUUC-Mlu-068004	Myotis lucifugus	93.36	0.00e+00	1093.00
IUUC-Nle-069163	Nomascus leucogenys	97.13	0.00e+00	1141.00
IUUC-Opr-070823	Ochotona princeps	95.38	0.00e+00	912.00
IUUC-Ont-071629	Oreochromis niloticus	61.39	0.00e+00	746.00
IUUC-Oan-072841	Ornithorhynchus anatinus	84.41	0.00e+00	1014.00
IUUC-Ocu-074300	Oryctolagus cuniculus	97.13	0.00e+00	1143.00
IUUC-Ola-087025	Oryzias latipes	57.83	0.00e+00	717.00
IUUC-Oga-088442	Otolemur garnettii	95.80	0.00e+00	1092.00
IUUC-Oar-089237	Ovis aries	96.78	0.00e+00	1136.00
IUUC-Ptr-091541	Pan troglodytes	96.95	0.00e+00	1139.00
IUUC-Psi-093748	Pelodiscus sinensis	77.96	0.00e+00	941.00
IUUC-Pma-094302	Petromyzon marinus	45.08	9.00e-101	360.00
IUUC-Pfo-097039	Poecilia formosa	60.79	0.00e+00	725.00
IUUC-Pab-098280	Pongo abelii	96.59	0.00e+00	1134.00
IUUC-Pca-100840	Procavia capensis	87.99	0.00e+00	1011.00
IUUC-Pva-102152	Pteropus vampyrus	96.59	0.00e+00	1134.00
IUUC-Rno-105710	Rattus norvegicus	98.74	0.00e+00	1153.00
IUUC-Sha-106991	Sarcophilus harrisii	88.17	0.00e+00	1056.00
IUUC-Sar-112931	Sorex araneus	96.06	0.00e+00	1134.00
IUUC-Ssc-116016	Sus scrofa	95.89	0.00e+00	1130.00
IUUC-Tgu-116999	Taeniopygia guttata	76.88	0.00e+00	925.00
IUUC-Tsy-119071	Tarsius syrichta	96.42	0.00e+00	1133.00
IUUC-Tni-120149	Tetraodon nigroviridis	56.68	0.00e+00	658.00
IUUC-Tbe-127651	Tupaia belangeri	97.31	0.00e+00	1142.00
IUUC-Ttr-128402	Tursiops truncatus	96.77	0.00e+00	1140.00
IUUC-Vpa-130186	Vicugna pacos	95.34	0.00e+00	1122.00
IUUC-Xtr-132379	Xenopus tropicalis	71.33	0.00e+00	877.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence