iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069035

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01179118

Gene Name

SH3RF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000006600.2	ENSNLET00000008416.2	ENSNLEP00000008031.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.40e-08	33.2	12	53
UBD/SH3	4.40e-48	161.1	448	503

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cle+++   +vlpC+H+f++ Cl  +      s++e rCP Cr
   Q: 12   CPVCLERLDASAKVLPCQHTFCKRCLLGI----VGSRNELRCPECR 53
           **********9**************9777....899*********8 PP

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +  ++y+y++ ++deL+l+kG++ lv  + +   gW kg++  + k G+fP n+v+ +
   Q: 448  VYVAIYPYTPRKEDELELRKGEMFLVF-ERC-QDGWFKGTSMHTSKIGVFPGNYVAPV 503
           5679**********************9.555.569********************988 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MDESALLDLL ECPVCLERLD ASAKVLPCQH TFCKRCLLGI VGSRNELRCP ECRTLVGSGV 60
EELPSNILLV RLLDGIKQRP WKPGPGGGSG TNCTNALRSQ SSTVANCSSK DLQSSQGGQQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTACATGAGT CATTTTAAGG GATGCACACA ACTATGAACA TTTCTGAAGC TTTTTTCTCA 60
GTAAAGTAGA TAAAGATGGA TGAATCAGCC TTGTTGGATC TTTTGGAGTG TCCTGTGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001452--SH3_domain
IPR028502--SH3RF1
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00018--SH3_1
PF14604--SH3_9
PF00097--zf-C3HC4

PRINTS

PR00452--SH3DOMAIN

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0046328--P:regulation of JNK cascade

KEGG

nle:100580786

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001528	Ailuropoda melanoleuca	90.00	0.00e+00	1349.00
IUUC-Apl-003961	Anas platyrhynchos	80.27	0.00e+00	1188.00
IUUC-Aca-004386	Anolis carolinensis	76.63	0.00e+00	1179.00
IUUC-Ame-010659	Astyanax mexicanus	72.99	1.00e-148	520.00
IUUC-Bta-012563	Bos taurus	89.32	1.00e-104	374.00
IUUC-Cja-019730	Callithrix jacchus	93.82	0.00e+00	1370.00
IUUC-Cfa-020992	Canis familiaris	91.24	0.00e+00	1385.00
IUUC-Cpo-021304	Cavia porcellus	92.35	0.00e+00	1455.00
IUUC-Csa-023925	Chlorocebus sabaeus	96.06	0.00e+00	1405.00
IUUC-Cho-024630	Choloepus hoffmanni	84.34	0.00e+00	887.00
IUUC-Cin-025274	Ciona intestinalis	48.71	4.00e-71	261.00
IUUC-Dre-028290	Danio rerio	60.64	0.00e+00	895.00
IUUC-Dno-029083	Dasypus novemcinctus	88.06	0.00e+00	1280.00
IUUC-Dor-030388	Dipodomys ordii	94.94	0.00e+00	678.00
IUUC-Dme-032207	Drosophila melanogaster	42.25	1.00e-63	238.00
IUUC-Ete-032809	Echinops telfairi	79.33	0.00e+00	840.00
IUUC-Eca-034185	Equus caballus	91.69	0.00e+00	1121.00
IUUC-Eeu-034816	Erinaceus europaeus	77.83	0.00e+00	1155.00
IUUC-Fca-036439	Felis catus	89.93	0.00e+00	1410.00
IUUC-Fal-037074	Ficedula albicollis	79.14	0.00e+00	1172.00
IUUC-Gmo-039443	Gadus morhua	69.11	9.00e-93	334.00
IUUC-Gga-040749	Gallus gallus	78.69	0.00e+00	1135.00
IUUC-Gac-041420	Gasterosteus aculeatus	73.84	4.00e-148	518.00
IUUC-Ggo-045215	Gorilla gorilla	99.10	0.00e+00	1483.00
IUUC-Hsa-046315	Homo sapiens	97.75	0.00e+00	1472.00
IUUC-Itr-048265	Ictidomys tridecemlineatus	90.77	3.00e-158	551.00
IUUC-Lch-049453	Latimeria chalumnae	69.82	0.00e+00	893.00
IUUC-Loc-052248	Lepisosteus oculatus	39.23	5.00e-76	278.00
IUUC-Laf-053651	Loxodonta africana	89.99	0.00e+00	1321.00
IUUC-Mcc-054688	Macaca mulatta	97.30	0.00e+00	1445.00
IUUC-Meu-056291	Macropus eugenii	75.07	0.00e+00	780.00
IUUC-Mga-059944	Meleagris gallopavo	77.79	0.00e+00	1159.00
IUUC-Mmr-061553	Microcebus murinus	91.43	0.00e+00	1264.00
IUUC-Mdo-062313	Monodelphis domestica	77.63	0.00e+00	1186.00
IUUC-Mmu-063516	Mus musculus	90.04	0.00e+00	1390.00
IUUC-Mpu-066064	Mustela putorius furo	90.53	0.00e+00	1363.00
IUUC-Mlu-067312	Myotis lucifugus	89.62	0.00e+00	1306.00
IUUC-Opr-070690	Ochotona princeps	86.84	0.00e+00	666.00
IUUC-Ont-071484	Oreochromis niloticus	58.36	0.00e+00	857.00
IUUC-Oan-073305	Ornithorhynchus anatinus	82.77	0.00e+00	1235.00
IUUC-Ocu-074936	Oryctolagus cuniculus	90.40	0.00e+00	1381.00
IUUC-Ola-086675	Oryzias latipes	60.69	2.00e-175	609.00
IUUC-Oga-087933	Otolemur garnettii	82.39	0.00e+00	1022.00
IUUC-Oar-090408	Ovis aries	61.57	1.00e-111	397.00
IUUC-Ptr-090865	Pan troglodytes	98.09	0.00e+00	1477.00
IUUC-Pan-092362	Papio anubis	96.17	0.00e+00	1404.00
IUUC-Psi-093876	Pelodiscus sinensis	79.62	0.00e+00	1213.00
IUUC-Pfo-097116	Poecilia formosa	66.18	0.00e+00	714.00
IUUC-Pab-098127	Pongo abelii	97.97	0.00e+00	1476.00
IUUC-Pca-100485	Procavia capensis	89.05	0.00e+00	1014.00
IUUC-Pva-102661	Pteropus vampyrus	89.52	0.00e+00	1295.00
IUUC-Rno-105728	Rattus norvegicus	88.85	0.00e+00	1377.00
IUUC-Sha-106515	Sarcophilus harrisii	86.32	0.00e+00	862.00
IUUC-Sar-113161	Sorex araneus	96.07	0.00e+00	672.00
IUUC-Ssc-115314	Sus scrofa	77.68	0.00e+00	1091.00
IUUC-Tgu-117012	Taeniopygia guttata	79.71	0.00e+00	1177.00
IUUC-Tru-118467	Takifugu rubripes	61.31	6.00e-159	554.00
IUUC-Tsy-119566	Tarsius syrichta	85.35	8.00e-176	610.00
IUUC-Tni-120830	Tetraodon nigroviridis	59.14	3.00e-167	582.00
IUUC-Tbe-128070	Tupaia belangeri	98.47	0.00e+00	728.00
IUUC-Ttr-128161	Tursiops truncatus	94.51	3.00e-143	502.00
IUUC-Xtr-132628	Xenopus tropicalis	72.31	0.00e+00	1078.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence