iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034246

UUCD1 version

UUC-EqC-00515

Ensembl Protein ID

ENSECAP00000016566.1

UniProt Accession

F6Z810; F6Z810_HORSE

Protein Name

Uncharacterized protein

Gene Name

TRIM27

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000019089.1	ENSECAT00000020197.1	ENSECAP00000016566.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	99.47	0.00e+00	694.00	IUUC-Hsa-046029
E3 activity/RING/RING	98.66	0.00e+00	690.00	IUUC-Mmu-064242

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Equus caballus

Protein Sequence
(Fasta)

QEQIHNQLDH LKRVKDLKKR RRAQGEQARA ELLSLTQMER EKIVWEFEQL YHSLKEHEYR 60
LLARLEELDL AIYNSINGAI TQFSCNISHL SSLIAQLEEK QQQPTRELLQ DIGDTLSRAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGAGCAAA TCCATAACCA GCTGGACCAC CTAAAACGAG TGAAAGACTT AAAGAAGAGG 60
CGTCGGGCAC AGGGGGAGCA GGCACGAGCT GAACTCTTGG TAAGGGTCAT TGGAATTCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom

PROSITE

PS50188--B302_SPRY

Pfam

PF13765--PRY
PF00622--SPRY

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0005768--C:endosome
GO:0001650--C:fibrillar center
GO:0031965--C:nuclear membrane
GO:0005654--C:nucleoplasm
GO:0030904--C:retromer complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0034314--P:Arp2/3 complex-mediated actin nucleation
GO:0045087--P:innate immune response
GO:0072643--P:interferon-gamma secretion
GO:0002820--P:negative regulation of adaptive immune response
GO:0090281--P:negative regulation of calcium ion import
GO:0045814--P:negative regulation of gene expression, epigenetic
GO:1900041--P:negative regulation of interleukin-2 secretion
GO:0006469--P:negative regulation of protein kinase activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0032720--P:negative regulation of tumor necrosis factor production
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0051127--P:positive regulation of actin nucleation
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0070534--P:protein K63-linked ubiquitination
GO:0070206--P:protein trimerization
GO:0042147--P:retrograde transport, endosome to Golgi

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001890	Ailuropoda melanoleuca	98.13	0.00e+00	693.00
IUUC-Ame-011197	Astyanax mexicanus	51.44	1.00e-53	203.00
IUUC-Bta-013520	Bos taurus	99.20	0.00e+00	693.00
IUUC-Cja-019557	Callithrix jacchus	98.66	0.00e+00	690.00
IUUC-Cfa-020583	Canis familiaris	98.93	0.00e+00	690.00
IUUC-Cpo-021738	Cavia porcellus	96.26	0.00e+00	672.00
IUUC-Csa-023502	Chlorocebus sabaeus	99.47	0.00e+00	694.00
IUUC-Cho-024563	Choloepus hoffmanni	93.72	5.00e-92	331.00
IUUC-Dno-029747	Dasypus novemcinctus	98.13	0.00e+00	685.00
IUUC-Dor-030243	Dipodomys ordii	95.99	0.00e+00	647.00
IUUC-Ete-032749	Echinops telfairi	87.68	1.00e-168	585.00
IUUC-Eeu-034481	Erinaceus europaeus	95.89	0.00e+00	648.00
IUUC-Fca-036152	Felis catus	98.66	0.00e+00	690.00
IUUC-Ggo-044987	Gorilla gorilla	86.20	4.00e-166	578.00
IUUC-Hsa-046029	Homo sapiens	99.47	0.00e+00	694.00
IUUC-Itr-048438	Ictidomys tridecemlineatus	99.20	0.00e+00	667.00
IUUC-Laf-054488	Loxodonta africana	99.20	0.00e+00	691.00
IUUC-Mcc-055352	Macaca mulatta	99.47	0.00e+00	694.00
IUUC-Mmr-060883	Microcebus murinus	99.20	0.00e+00	692.00
IUUC-Mmu-064242	Mus musculus	98.66	0.00e+00	690.00
IUUC-Mpu-065958	Mustela putorius furo	98.66	0.00e+00	691.00
IUUC-Mlu-068005	Myotis lucifugus	87.94	0.00e+00	636.00
IUUC-Nle-069710	Nomascus leucogenys	98.60	4.00e-96	344.00
IUUC-Opr-071200	Ochotona princeps	99.20	0.00e+00	693.00
IUUC-Ocu-074081	Oryctolagus cuniculus	97.15	1.00e-158	552.00
IUUC-Oga-088784	Otolemur garnettii	99.20	0.00e+00	693.00
IUUC-Oar-089433	Ovis aries	99.20	0.00e+00	693.00
IUUC-Ptr-090595	Pan troglodytes	99.47	0.00e+00	694.00
IUUC-Pan-092027	Papio anubis	99.47	0.00e+00	694.00
IUUC-Pab-098331	Pongo abelii	99.47	0.00e+00	694.00
IUUC-Pca-101091	Procavia capensis	99.20	0.00e+00	692.00
IUUC-Pva-103141	Pteropus vampyrus	98.93	0.00e+00	694.00
IUUC-Rno-105507	Rattus norvegicus	98.66	0.00e+00	690.00
IUUC-Sar-113713	Sorex araneus	95.01	2.00e-178	618.00
IUUC-Ssc-115594	Sus scrofa	99.20	0.00e+00	695.00
IUUC-Tsy-119235	Tarsius syrichta	99.46	0.00e+00	694.00
IUUC-Tbe-127796	Tupaia belangeri	88.64	3.00e-140	491.00
IUUC-Ttr-128738	Tursiops truncatus	99.20	0.00e+00	692.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence