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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046965
UUCD1 version UUC-HoS-00420
Ensembl Protein ID ENSP00000337510.4
UniProt Accession Q9UH90; B2RAX7; Q32M70; Q9ULM5; FBX40_HUMAN
Genbank Protein ID AAF17085.1; BAA86509.1; BAG37024.1; EAW79508.1; AAI09276.1; AAI09277.1
Protein Name F-box only protein 40; Muscle disease-related protein
Genbank Nucleotide ID AF204674; AB033021; AK314400; AC063920; BC109275; BC109276
Gene Name FBXO40; FBX40; KIAA1195
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000163833.7 ENST00000338040.5 ENSP00000337510.4
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICHPM
DNA & RNA Element
UTRdbAREsitemiRTarBasemicroRNA
TRANSFACTargetScanRepTarmiRcode
RAID2
Protein-protein Interaction
iRefIndexMenthaInWeb_IM
Disease-associated Information
GWASdbOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
BioGRIDmUbiSiDa
DNA Methylation
MethyCancerTCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
E3 adaptor/Cullin RING/SCF/F-box F-box 22033112
Organism Homo sapiens
Functional Description
(View)

Functional Description


     Probable substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex that may function in myogenesis.
 Probable substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex that may function in myogenesis.
Protein Sequence
(Fasta)
MGKARRSPPG HHRHCEGCFN RHCHIPVEPN TSCLVISCHL LCGATFHMCK EAEHQLLCPL 60
EQVPCLNSEY GCPLSMSRHK LAKHLQVCPA SVVCCSMEWN RWPNVDSETT LHENIMKETP 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046965|E3,F-box|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTGTTCTGGC CTTGAAAATG ATCCTTCTTA AAAGGATTTT CCTCCTTCCT CAAGGGAAAG 60
AAAACCTATT GATATAAAAC TTCACTTCCC ATTCAGTTTC CCCTGCTAAA TGCCACTCCA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046965|E3,F-box|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0479--Metal-binding
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001810--F-box_dom
IPR031890--Fbxo30/Fbxo40
IPR008974--TRAF-like
IPR013083--Znf_RING/FYVE/PHD
IPR001293--Znf_TRAF
PROSITE

PS50181--FBOX
PS50145--ZF_TRAF
Pfam

PF15966--F-box_4
PF15965--zf-TRAF_2
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0042692--P:muscle cell differentiation
GO:0000209--P:protein polyubiquitination
KEGG hsa:51725
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001882 Ailuropoda melanoleuca 89.70 0.00e+00 1214.00
IUUC-Apl-003788 Anas platyrhynchos 65.96 0.00e+00 907.00
IUUC-Aca-004624 Anolis carolinensis 61.40 0.00e+00 871.00
IUUC-Afl-008411 Aspergillus flavus 25.21 7.90e-02 30.00
IUUC-Ame-011599 Astyanax mexicanus 50.42 0.00e+00 706.00
IUUC-Bta-013376 Bos taurus 87.38 0.00e+00 1214.00
IUUC-Cja-019840 Callithrix jacchus 95.06 0.00e+00 1291.00
IUUC-Cfa-020146 Canis familiaris 86.78 0.00e+00 1205.00
IUUC-Cpo-021483 Cavia porcellus 85.45 0.00e+00 1225.00
IUUC-Csa-023141 Chlorocebus sabaeus 97.88 0.00e+00 1316.00
IUUC-Cho-024945 Choloepus hoffmanni 86.44 0.00e+00 1263.00
IUUC-Dre-027812 Danio rerio 45.30 2.00e-172 599.00
IUUC-Dno-030088 Dasypus novemcinctus 88.19 0.00e+00 1235.00
IUUC-Dor-030549 Dipodomys ordii 87.18 0.00e+00 1264.00
IUUC-Eca-034434 Equus caballus 90.01 0.00e+00 1258.00
IUUC-Eeu-035064 Erinaceus europaeus 86.16 0.00e+00 1244.00
IUUC-Fca-035523 Felis catus 85.37 0.00e+00 1182.00
IUUC-Fal-037137 Ficedula albicollis 64.44 0.00e+00 879.00
IUUC-Gmo-039031 Gadus morhua 46.79 0.00e+00 639.00
IUUC-Gga-040532 Gallus gallus 66.72 0.00e+00 772.00
IUUC-Gac-041371 Gasterosteus aculeatus 47.19 0.00e+00 646.00
IUUC-Gma-042970 Glycine max 25.31 1.00e-02 35.80
IUUC-Ggo-044453 Gorilla gorilla 99.29 0.00e+00 1373.00
IUUC-Itr-048530 Ictidomys tridecemlineatus 87.91 0.00e+00 1245.00
IUUC-Kpa-049103 Komagataella pastoris 32.20 8.20e-02 32.30
IUUC-Lch-049573 Latimeria chalumnae 57.00 0.00e+00 816.00
IUUC-Loc-052475 Lepisosteus oculatus 53.55 0.00e+00 759.00
IUUC-Laf-054424 Loxodonta africana 87.06 0.00e+00 1275.00
IUUC-Mcc-055243 Macaca mulatta 97.74 0.00e+00 1318.00
IUUC-Meu-055909 Macropus eugenii 77.20 0.00e+00 1122.00
IUUC-Mga-060045 Meleagris gallopavo 65.53 0.00e+00 935.00
IUUC-Mmr-061531 Microcebus murinus 84.81 0.00e+00 1143.00
IUUC-Mdo-062838 Monodelphis domestica 78.95 0.00e+00 1122.00
IUUC-Mmu-064229 Mus musculus 84.91 0.00e+00 1236.00
IUUC-Mpu-066012 Mustela putorius furo 89.82 0.00e+00 1190.00
IUUC-Mlu-067170 Myotis lucifugus 88.54 0.00e+00 1239.00
IUUC-Nle-069819 Nomascus leucogenys 98.17 0.00e+00 1365.00
IUUC-Ont-072664 Oreochromis niloticus 49.22 0.00e+00 667.00
IUUC-Oan-072948 Ornithorhynchus anatinus 58.88 0.00e+00 776.00
IUUC-Ocu-074610 Oryctolagus cuniculus 88.01 0.00e+00 1288.00
IUUC-Ola-087480 Oryzias latipes 47.94 0.00e+00 629.00
IUUC-Oga-088445 Otolemur garnettii 88.42 0.00e+00 1264.00
IUUC-Oar-089876 Ovis aries 86.97 0.00e+00 1201.00
IUUC-Ptr-090727 Pan troglodytes 99.44 0.00e+00 1377.00
IUUC-Pan-092488 Papio anubis 97.88 0.00e+00 1318.00
IUUC-Psi-093321 Pelodiscus sinensis 64.13 0.00e+00 820.00
IUUC-Pno-095023 Phaeosphaeria nodorum 31.88 1.00e-03 38.10
IUUC-Pfo-097321 Poecilia formosa 49.57 0.00e+00 671.00
IUUC-Pab-097637 Pongo abelii 98.59 0.00e+00 1364.00
IUUC-Pca-100632 Procavia capensis 88.21 0.00e+00 903.00
IUUC-Pva-102503 Pteropus vampyrus 88.31 0.00e+00 1263.00
IUUC-Ptt-103857 Puccinia triticina 31.91 6.60e-02 32.30
IUUC-Rno-105321 Rattus norvegicus 85.19 0.00e+00 1199.00
IUUC-Sha-106906 Sarcophilus harrisii 78.03 0.00e+00 1087.00
IUUC-Sar-113603 Sorex araneus 86.32 0.00e+00 1239.00
IUUC-Ssc-116153 Sus scrofa 81.33 0.00e+00 1117.00
IUUC-Tgu-117476 Taeniopygia guttata 64.31 0.00e+00 886.00
IUUC-Tru-118371 Takifugu rubripes 46.02 1.00e-173 603.00
IUUC-Tsy-118977 Tarsius syrichta 71.26 2.00e-139 489.00
IUUC-Tni-119795 Tetraodon nigroviridis 46.61 3.00e-178 619.00
IUUC-Tae-124508 Triticum aestivum 23.13 1.70e-01 31.20
IUUC-Tbe-127246 Tupaia belangeri 89.31 0.00e+00 1283.00
IUUC-Ttr-128674 Tursiops truncatus 85.63 0.00e+00 1131.00
IUUC-Vpa-130395 Vicugna pacos 83.80 0.00e+00 1147.00
IUUC-Xtr-132899 Xenopus tropicalis 57.76 0.00e+00 829.00
Created Date 25-Jun-2017

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