iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.40e-11	44.5	1064	1111

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
            C+vC++g++ e +++ C++C+   H  Clk++  +++p  + w+C++C +
   Q: 1064 LCKVCRRGSDPE-KMLLCDECNAGTHMFCLKPK-LRSVPPGN-WYCNDCVK 1111
           7*********88.69******************.99999996.******75 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MPICKREGFD LNQKEGKNET FHDNDQVFCC YITKRIFRDY EHYFRHVMVI NSTVWQCEAT 60
GKENLTYEEA VKSERAARKK MEQFKQSLRA PVLLVVEHAQ QSAVNTLNMI VAKFLRKRYF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGATAACCGA TAGTTTAACG TCGAAGAGCG ATAGGCCCCA AAATATGCGC GTGAAAATAG 60
ATTGTGCGCT ATAAAATAAA CGGATTTAGG TAGTTGGTGT TGAGGAAGCC AGCCACAAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0012--Acyltransferase
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001487--Bromodomain
IPR018501--DDT_dom
IPR028941--WHIM2_dom
IPR013136--WSTF_Acf1_Cbp146
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50014--BROMODOMAIN_2
PS50827--DDT
PS51136--WAC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00439--Bromodomain
PF00628--PHD
PF10537--WAC_Acf1_DNA_bd
PF15613--WSD

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00571--DDT
SM00249--PHD

Gene Ontology

GO:0016590--C:ACF complex
GO:0008623--C:CHRAC
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0070615--F:nucleosome-dependent ATPase activity
GO:0016746--F:transferase activity, transferring acyl groups
GO:0008270--F:zinc ion binding
GO:0031497--P:chromatin assembly
GO:0006333--P:chromatin assembly or disassembly
GO:0048813--P:dendrite morphogenesis
GO:0008544--P:epidermis development
GO:0007517--P:muscle organ development
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0007399--P:nervous system development
GO:0048666--P:neuron development
GO:0006334--P:nucleosome assembly
GO:0042766--P:nucleosome mobilization
GO:0016584--P:nucleosome positioning
GO:0043462--P:regulation of ATPase activity
GO:0031445--P:regulation of heterochromatin assembly
GO:0006355--P:regulation of transcription, DNA-templated
GO:0019233--P:sensory perception of pain

KEGG

dme:Dmel_CG1966

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002389	Ailuropoda melanoleuca	26.64	4.00e-42	166.00
IUUC-Apl-004078	Anas platyrhynchos	27.23	1.00e-41	165.00
IUUC-Aca-004951	Anolis carolinensis	27.70	1.00e-42	168.00
IUUC-Ame-011469	Astyanax mexicanus	38.95	1.00e-18	88.60
IUUC-Bta-012850	Bos taurus	26.95	1.00e-42	167.00
IUUC-Cja-018999	Callithrix jacchus	26.00	2.00e-40	161.00
IUUC-Cfa-020916	Canis familiaris	27.09	3.00e-42	167.00
IUUC-Cpo-022146	Cavia porcellus	27.37	2.00e-40	160.00
IUUC-Cre-022637	Chlamydomonas reinhardtii	46.15	2.00e-08	49.30
IUUC-Csa-024039	Chlorocebus sabaeus	26.71	1.00e-41	165.00
IUUC-Cho-024914	Choloepus hoffmanni	26.75	1.00e-42	168.00
IUUC-Cin-025450	Ciona intestinalis	34.02	3.00e-32	132.00
IUUC-Csv-026068	Ciona savignyi	45.74	1.00e-29	121.00
IUUC-Dre-027413	Danio rerio	31.48	2.00e-35	144.00
IUUC-Dno-029438	Dasypus novemcinctus	25.94	9.00e-46	178.00
IUUC-Dor-030625	Dipodomys ordii	37.50	6.00e-20	92.80
IUUC-Ete-033052	Echinops telfairi	29.03	2.00e-37	150.00
IUUC-Eca-034262	Equus caballus	40.80	1.00e-27	119.00
IUUC-Eeu-034704	Erinaceus europaeus	31.84	1.00e-33	138.00
IUUC-Fca-036207	Felis catus	27.12	2.00e-40	160.00
IUUC-Fal-036702	Ficedula albicollis	27.25	3.00e-38	154.00
IUUC-Gmo-039218	Gadus morhua	44.09	8.00e-28	119.00
IUUC-Gga-040776	Gallus gallus	27.01	1.00e-40	161.00
IUUC-Gac-042358	Gasterosteus aculeatus	30.86	1.00e-30	128.00
IUUC-Ggo-045317	Gorilla gorilla	37.23	1.00e-19	92.40
IUUC-Hsa-046560	Homo sapiens	30.18	2.00e-38	154.00
IUUC-Itr-048135	Ictidomys tridecemlineatus	27.67	3.00e-43	169.00
IUUC-Lch-050271	Latimeria chalumnae	40.79	4.00e-17	84.00
IUUC-Loc-052699	Lepisosteus oculatus	39.58	2.00e-20	94.70
IUUC-Laf-054049	Loxodonta africana	29.97	8.00e-40	159.00
IUUC-Mcc-055171	Macaca mulatta	37.23	1.00e-19	92.40
IUUC-Meu-055990	Macropus eugenii	40.00	4.00e-20	93.60
IUUC-Mga-059382	Meleagris gallopavo	27.42	1.00e-40	161.00
IUUC-Mmr-061301	Microcebus murinus	26.15	5.00e-41	162.00
IUUC-Mdo-062889	Monodelphis domestica	28.57	5.00e-41	162.00
IUUC-Mmu-064057	Mus musculus	29.62	8.00e-38	152.00
IUUC-Mpu-066668	Mustela putorius furo	26.51	2.00e-42	167.00
IUUC-Mlu-068089	Myotis lucifugus	30.52	3.00e-39	157.00
IUUC-Nle-069936	Nomascus leucogenys	26.71	2.00e-42	167.00
IUUC-Opr-070678	Ochotona princeps	37.50	4.00e-20	93.60
IUUC-Ont-071565	Oreochromis niloticus	43.37	2.00e-20	94.70
IUUC-Oan-073582	Ornithorhynchus anatinus	31.32	2.00e-38	154.00
IUUC-Ocu-074115	Oryctolagus cuniculus	24.73	1.00e-40	161.00
IUUC-Ola-086709	Oryzias latipes	32.14	4.00e-32	133.00
IUUC-Oga-088100	Otolemur garnettii	26.42	1.00e-39	157.00
IUUC-Oar-089208	Ovis aries	29.38	2.00e-37	151.00
IUUC-Ptr-090630	Pan troglodytes	30.18	5.00e-39	156.00
IUUC-Pan-092146	Papio anubis	29.64	2.00e-37	150.00
IUUC-Psi-092932	Pelodiscus sinensis	27.20	6.00e-40	159.00
IUUC-Pfo-096572	Poecilia formosa	33.04	2.00e-27	118.00
IUUC-Pab-098679	Pongo abelii	37.23	1.00e-19	92.00
IUUC-Pva-102893	Pteropus vampyrus	27.04	3.00e-42	167.00
IUUC-Rno-105098	Rattus norvegicus	29.46	3.00e-37	150.00
IUUC-Sha-106513	Sarcophilus harrisii	29.91	3.00e-38	153.00
IUUC-Sar-113192	Sorex araneus	40.46	6.00e-28	119.00
IUUC-Ssc-116407	Sus scrofa	30.47	1.00e-39	158.00
IUUC-Tgu-117403	Taeniopygia guttata	27.06	8.00e-38	152.00
IUUC-Tru-118124	Takifugu rubripes	33.73	8.00e-40	159.00
IUUC-Tsy-119386	Tarsius syrichta	30.99	8.00e-40	159.00
IUUC-Ttr-128885	Tursiops truncatus	37.50	7.00e-20	92.80
IUUC-Vpa-130046	Vicugna pacos	30.47	9.00e-40	159.00
IUUC-Xtr-132132	Xenopus tropicalis	31.32	6.00e-38	152.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence