iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067509

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02040949

Gene Name

OTUB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000001148.2	ENSMLUT00000001150.2	ENSMLUP00000001052.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	1.00e-47	162.0	41	229

Active Site

Position(s)	Description	Evidence
48	N/A	{ECO:0000256\|PIRSR:PIRSR013503-1}
51	Nucleophile	{ECO:0000256\|PIRSR:PIRSR013503-1}
223		{ECO:0000256\|PIRSR:PIRSR013503-1}

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqs.........................................................llgvfdddslsda 33
           +i+ktkgDGnC++rA+++s                                                         ll+vf+d+s+sd 
   Q: 41   AIRKTKGDGNCFYRALGYSylesllgkgrevlkfkervlqtpndlltagfeehkfrnffnafysvvelvekdgvasLLKVFNDQSASDR 129
           699************************************************************************************** PP
   S: 34   lveaLreltseylqkesdffsefieekedekefcqklvepeak.geeihifaLaqiLsrpiivvdvdsleskvggillpllfpeeklkk 121
           +v++Lr+lts+++++++dff++fi+e++d+k+fc+++vep+a  +++i+i+aL+q+Ls++++v++vd++++    +l++++fpe++  +
   Q: 130  IVQFLRLLTSAFIRNRADFFRHFIDEEMDIKDFCTHEVEPMAMeCDHIQITALSQALSIALQVEYVDEMDT----ALNHHVFPEAA-IP 213
           *********************************************************************95....***********.** PP
   S: 122  pivLlYrsgHYdaLva 137
           +++LlY+++HY++L+a
   Q: 214  SVYLLYKTSHYNILYA 229
           **************97 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

QTETSFHLIS EKCDILSILR DHPENRIYQR KIQELSKRFI AIRKTKGDGN CFYRALGYSY 60
LESLLGKGRE VLKFKERVLQ TPNDLLTAGF EEHKFRNFFN AFYSVVELVE KDGVASLLKV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGACTGAAA CATCTTTCCA CCTAATATCA GAGAAATGTG ACATTCTCTC AATTCTCCGG 60
GATCATCCTG AAAACAGGAT TTACCAGAGG AAAATCCAGG TGAGGCAGGG GGTCGGGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR030299--OTUB2
IPR016615--Otubain
IPR019400--Peptidase_C65_otubain

PROSITE

PS50802--OTU

Pfam

PF10275--Peptidase_C65

Gene Ontology

GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002059	Ailuropoda melanoleuca	94.02	8.00e-130	455.00
IUUC-Bta-012766	Bos taurus	94.40	1.00e-128	451.00
IUUC-Cja-019480	Callithrix jacchus	92.21	1.00e-125	442.00
IUUC-Cfa-021106	Canis familiaris	94.44	1.00e-130	458.00
IUUC-Cpo-022187	Cavia porcellus	93.56	1.00e-128	452.00
IUUC-Csa-023493	Chlorocebus sabaeus	93.99	2.00e-128	451.00
IUUC-Cho-024411	Choloepus hoffmanni	74.63	2.00e-82	297.00
IUUC-Dno-029346	Dasypus novemcinctus	93.99	2.00e-129	454.00
IUUC-Dor-031012	Dipodomys ordii	95.69	1.00e-130	458.00
IUUC-Ete-032266	Echinops telfairi	86.70	4.00e-118	416.00
IUUC-Eca-033356	Equus caballus	96.15	2.00e-132	464.00
IUUC-Eeu-034775	Erinaceus europaeus	94.85	8.00e-131	459.00
IUUC-Fca-035363	Felis catus	92.70	9.00e-128	448.00
IUUC-Ggo-045023	Gorilla gorilla	93.53	2.00e-127	447.00
IUUC-Hsa-046984	Homo sapiens	93.97	6.00e-128	449.00
IUUC-Itr-048012	Ictidomys tridecemlineatus	93.10	2.00e-128	450.00
IUUC-Lch-050514	Latimeria chalumnae	61.16	1.00e-81	296.00
IUUC-Loc-052003	Lepisosteus oculatus	50.90	4.00e-63	234.00
IUUC-Laf-054382	Loxodonta africana	92.74	1.00e-128	451.00
IUUC-Mcc-055516	Macaca mulatta	93.56	5.00e-128	449.00
IUUC-Meu-056038	Macropus eugenii	85.71	1.00e-95	341.00
IUUC-Mmr-060918	Microcebus murinus	94.40	3.00e-129	454.00
IUUC-Mdo-062638	Monodelphis domestica	87.50	3.00e-120	424.00
IUUC-Mmu-063973	Mus musculus	93.99	1.00e-129	455.00
IUUC-Mpu-066013	Mustela putorius furo	94.85	3.00e-130	457.00
IUUC-Nle-069673	Nomascus leucogenys	93.97	6.00e-128	449.00
IUUC-Opr-070761	Ochotona princeps	85.45	2.00e-78	283.00
IUUC-Oan-072922	Ornithorhynchus anatinus	80.35	6.00e-109	386.00
IUUC-Ocu-074643	Oryctolagus cuniculus	93.97	9.00e-129	452.00
IUUC-Oni-082026	Oryza nivara	30.10	6.00e-15	75.50
IUUC-Oru-084761	Oryza rufipogon	30.10	6.00e-15	75.50
IUUC-Ola-086603	Oryzias latipes	45.37	7.00e-50	190.00
IUUC-Oga-088936	Otolemur garnettii	95.71	3.00e-131	460.00
IUUC-Oar-089460	Ovis aries	94.42	9.00e-129	452.00
IUUC-Ptr-090805	Pan troglodytes	93.53	1.00e-127	448.00
IUUC-Pan-091969	Papio anubis	93.97	6.00e-128	449.00
IUUC-Pab-098476	Pongo abelii	93.56	5.00e-128	449.00
IUUC-Pca-100252	Procavia capensis	89.00	3.00e-51	194.00
IUUC-Pva-102204	Pteropus vampyrus	92.67	1.00e-127	448.00
IUUC-Pgr-103552	Puccinia graminis	60.87	2.60e-02	31.20
IUUC-Rno-105062	Rattus norvegicus	93.97	2.00e-129	454.00
IUUC-Sha-106968	Sarcophilus harrisii	87.39	2.00e-119	421.00
IUUC-Sar-113295	Sorex araneus	93.99	1.00e-127	448.00
IUUC-Ssc-115288	Sus scrofa	94.42	5.00e-130	456.00
IUUC-Tni-120440	Tetraodon nigroviridis	37.72	2.00e-41	161.00
IUUC-Tbe-127717	Tupaia belangeri	91.89	2.00e-75	274.00
IUUC-Ttr-128221	Tursiops truncatus	75.11	1.00e-97	348.00
IUUC-Uma-129443	Ustilago maydis	33.80	4.00e-26	112.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence