iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003384

Ensembl Protein ID

ENSAPLP00000013185.1

UniProt Accession

U3J108; U3J108_ANAPL

Genbank Protein ID

ENSAPLP00000013185

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01136980

Gene Name

ATG16L1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000013322.1	ENSAPLT00000013933.1	ENSAPLP00000013185.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.80e-33	111.8	377	416
UBD/Beta-Prp	6.30e-64	215.7	287	576

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllks 38
           gH+++v + +f  ++ ++vsGs+D t+k+WDlr+ v++k+
   Q: 377  GHSGKVLSAKFllDNARIVSGSHDRTLKLWDLRSKVCIKT 416
           8***********64489********************985 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtl 90
           +++++h++ +++v+fsp+++llatg++d+++k+w+v    +    slsg +a++t+++f++ g++l+ +s+D + ++w ++++   htl
   Q: 287  CVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVLGDRCepKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDNRLRHTL 375
           7899**********************************999999********************************************* PP
   S: 91   kghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltggh 179
           +gh+ +vls +f  ++ ++vsGshdrt+++wdl+++ c++++++g +    c  + +++++++sG+ D+++r+Wd++t++++++l+   
   Q: 376  TGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSS----CNDIVCTEQCVMSGHFDKKIRFWDIRTESIVKELE--L 458
           ****************************************9999988....888888889*************************6..6 PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght....dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn 264
            ++++ l+++s+++el+++s+d  +k+ dl+ g + +t+ ++     +  ++v fsp++++++ gs+Dg ++iW++ +g+l +tl++h+
   Q: 459  LGRITALDLNSERTELLTCSRDDLLKIIDLRVGAVKQTFSAQGfkcgSDWTRVVFSPDGNYVAAGSADGALYIWNVLTGKLERTLAKHH 547
           9********************************99888888887788777779************************************ PP
   S: 265  ssvisvavlsfgdnvlvlgsedskvniwk 293
           ss+i   ++s+ + ++v++++ +k+ +w+
   Q: 548  SSSINAVAWSPAGAHVVSVDKGNKAVLWA 576
           *********************99999996 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

XFEEIIAQYN KLLEKSDLHA VLADKLQAEK YDMQSRHEIS PGHDGTWNDA QLQELAQLKI 60
KHQEELTELH KKRGELAQSV IDLNNQMQQK DKEMQMNEAK IAEYLQKISE LETECQELRS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NCCTTCGAGG AGATCATCGC GCAGTGTAAG GGGCCTGGGG GCCCGGGGGC CTCCGCTCGT 60
CGCCTTGTGC GAGGAGCGGC GGCGGGGCGC TGCTCGGTTC GCTTTGTGGC GGAATCAGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR012284--6PGD_dom_3
IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000421--C:autophagosome membrane
GO:0005930--C:axoneme
GO:0039689--P:negative stranded viral RNA replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000090	Aegilops tauschii	28.52	2.00e-32	133.00
IUUC-Aml-002242	Ailuropoda melanoleuca	83.62	0.00e+00	975.00
IUUC-Atr-003073	Amborella trichopoda	24.95	4.00e-31	129.00
IUUC-Aca-004962	Anolis carolinensis	87.52	0.00e+00	1030.00
IUUC-Aly-005435	Arabidopsis lyrata	34.44	2.00e-45	176.00
IUUC-Ath-006948	Arabidopsis thaliana	34.44	5.00e-46	178.00
IUUC-Ame-010915	Astyanax mexicanus	80.67	2.00e-157	547.00
IUUC-Bta-012388	Bos taurus	86.34	0.00e+00	1054.00
IUUC-Bdi-014231	Brachypodium distachyon	25.38	2.00e-39	156.00
IUUC-Bol-016174	Brassica oleracea	35.43	7.00e-47	181.00
IUUC-Bra-017165	Brassica rapa	34.77	3.00e-46	179.00
IUUC-Cel-018131	Caenorhabditis elegans	30.48	4.00e-65	242.00
IUUC-Cja-018898	Callithrix jacchus	77.53	0.00e+00	875.00
IUUC-Cfa-020484	Canis familiaris	88.39	0.00e+00	1048.00
IUUC-Cpo-022156	Cavia porcellus	87.00	0.00e+00	1023.00
IUUC-Csa-024019	Chlorocebus sabaeus	84.92	0.00e+00	991.00
IUUC-Cho-024311	Choloepus hoffmanni	73.57	0.00e+00	866.00
IUUC-Cin-025260	Ciona intestinalis	37.18	1.00e-102	366.00
IUUC-Csv-025836	Ciona savignyi	44.71	6.00e-49	186.00
IUUC-Dre-027702	Danio rerio	74.41	0.00e+00	889.00
IUUC-Dno-029728	Dasypus novemcinctus	84.01	0.00e+00	1040.00
IUUC-Dor-030587	Dipodomys ordii	85.12	3.00e-94	338.00
IUUC-Dme-031595	Drosophila melanogaster	40.00	1.00e-113	403.00
IUUC-Ete-032969	Echinops telfairi	71.57	0.00e+00	727.00
IUUC-Eca-034214	Equus caballus	89.25	0.00e+00	894.00
IUUC-Eeu-034537	Erinaceus europaeus	82.63	0.00e+00	847.00
IUUC-Fca-036005	Felis catus	85.37	0.00e+00	1001.00
IUUC-Fal-037593	Ficedula albicollis	95.37	0.00e+00	1100.00
IUUC-Gmo-039042	Gadus morhua	65.22	0.00e+00	685.00
IUUC-Gga-040986	Gallus gallus	95.78	0.00e+00	1147.00
IUUC-Gac-041351	Gasterosteus aculeatus	73.77	0.00e+00	905.00
IUUC-Gma-043265	Glycine max	28.98	5.00e-54	204.00
IUUC-Ggo-045427	Gorilla gorilla	85.02	0.00e+00	1010.00
IUUC-Hsa-046632	Homo sapiens	87.35	0.00e+00	1031.00
IUUC-Itr-048504	Ictidomys tridecemlineatus	83.22	0.00e+00	972.00
IUUC-Lch-049439	Latimeria chalumnae	50.00	2.00e-144	505.00
IUUC-Lpe-051254	Leersia perrieri	30.56	1.00e-38	154.00
IUUC-Loc-052610	Lepisosteus oculatus	76.60	0.00e+00	908.00
IUUC-Laf-053936	Loxodonta africana	82.58	0.00e+00	1005.00
IUUC-Mcc-055504	Macaca mulatta	82.52	0.00e+00	1031.00
IUUC-Meu-056516	Macropus eugenii	81.65	0.00e+00	964.00
IUUC-Mtr-058062	Medicago truncatula	26.74	4.00e-48	185.00
IUUC-Mga-059777	Meleagris gallopavo	97.92	0.00e+00	1159.00
IUUC-Mmr-061298	Microcebus murinus	86.34	0.00e+00	1027.00
IUUC-Mdo-062969	Monodelphis domestica	86.49	0.00e+00	1050.00
IUUC-Mmu-064076	Mus musculus	83.95	0.00e+00	995.00
IUUC-Mac-065161	Musa acuminata	25.19	9.00e-40	157.00
IUUC-Mpu-066196	Mustela putorius furo	86.00	0.00e+00	1026.00
IUUC-Mlu-067651	Myotis lucifugus	86.85	0.00e+00	1032.00
IUUC-Nle-069853	Nomascus leucogenys	86.31	0.00e+00	1016.00
IUUC-Opr-070350	Ochotona princeps	87.80	3.00e-111	395.00
IUUC-Ont-072489	Oreochromis niloticus	74.87	0.00e+00	899.00
IUUC-Oan-072703	Ornithorhynchus anatinus	80.37	0.00e+00	942.00
IUUC-Ocu-074205	Oryctolagus cuniculus	83.98	0.00e+00	1016.00
IUUC-Oba-075619	Oryza barthii	30.88	3.00e-37	149.00
IUUC-Obr-076632	Oryza brachyantha	30.39	6.00e-39	155.00
IUUC-Ogl-077671	Oryza glaberrima	30.88	3.00e-37	149.00
IUUC-Ogu-078052	Oryza glumaepatula	30.88	3.00e-37	149.00
IUUC-Oin-079611	Oryza indica	30.53	5.00e-35	141.00
IUUC-Olo-080408	Oryza longistaminata	30.88	6.00e-37	148.00
IUUC-Ome-081560	Oryza meridionalis	30.88	3.00e-37	149.00
IUUC-Oni-082145	Oryza nivara	30.88	3.00e-37	149.00
IUUC-Opu-083918	Oryza punctata	30.53	1.00e-36	147.00
IUUC-Oru-084858	Oryza rufipogon	30.53	7.00e-35	141.00
IUUC-Osa-086277	Oryza sativa	30.53	5.00e-35	142.00
IUUC-Ola-086816	Oryzias latipes	73.83	2.00e-102	364.00
IUUC-Olu-087622	Ostreococcus lucimarinus	35.33	4.00e-44	171.00
IUUC-Oga-088765	Otolemur garnettii	83.74	0.00e+00	942.00
IUUC-Oar-090196	Ovis aries	83.92	0.00e+00	946.00
IUUC-Ptr-091676	Pan troglodytes	87.52	0.00e+00	1033.00
IUUC-Pan-092068	Papio anubis	85.69	0.00e+00	1019.00
IUUC-Psi-093367	Pelodiscus sinensis	93.07	0.00e+00	1072.00
IUUC-Ppa-095699	Physcomitrella patens	28.94	6.00e-42	164.00
IUUC-Pfo-096067	Poecilia formosa	74.44	0.00e+00	877.00
IUUC-Pab-098111	Pongo abelii	85.02	0.00e+00	1010.00
IUUC-Pop-099116	Populus trichocarpa	33.99	2.00e-44	173.00
IUUC-Pca-100680	Procavia capensis	75.80	0.00e+00	831.00
IUUC-Ppe-101790	Prunus persica	26.21	4.00e-47	181.00
IUUC-Pva-102871	Pteropus vampyrus	82.79	0.00e+00	982.00
IUUC-Rno-106088	Rattus norvegicus	83.28	0.00e+00	986.00
IUUC-Sha-106984	Sarcophilus harrisii	87.89	0.00e+00	1061.00
IUUC-Smo-109404	Selaginella moellendorffii	27.65	7.00e-45	174.00
IUUC-Sit-110828	Setaria italica	26.72	2.00e-44	173.00
IUUC-Sly-111009	Solanum lycopersicum	26.74	3.00e-49	189.00
IUUC-Stu-112370	Solanum tuberosum	27.31	6.00e-51	194.00
IUUC-Sar-113659	Sorex araneus	60.61	2.00e-87	314.00
IUUC-Sbi-114819	Sorghum bicolor	25.00	1.00e-41	164.00
IUUC-Ssc-116241	Sus scrofa	86.75	0.00e+00	1016.00
IUUC-Tgu-116576	Taeniopygia guttata	98.44	0.00e+00	1167.00
IUUC-Tru-118336	Takifugu rubripes	66.61	0.00e+00	758.00
IUUC-Tsy-119006	Tarsius syrichta	82.46	0.00e+00	967.00
IUUC-Tni-120300	Tetraodon nigroviridis	76.51	0.00e+00	886.00
IUUC-Tca-121002	Theobroma cacao	28.13	6.00e-52	198.00
IUUC-Tae-124868	Triticum aestivum	29.18	1.00e-33	137.00
IUUC-Tur-126463	Triticum urartu	28.52	8.00e-33	135.00
IUUC-Tbe-127631	Tupaia belangeri	88.68	0.00e+00	860.00
IUUC-Ttr-129005	Tursiops truncatus	78.02	2.00e-153	535.00
IUUC-Vpa-130246	Vicugna pacos	77.15	0.00e+00	751.00
IUUC-Vvi-130878	Vitis vinifera	35.35	3.00e-46	179.00
IUUC-Xtr-132798	Xenopus tropicalis	75.13	0.00e+00	867.00
IUUC-Xma-133264	Xiphophorus maculatus	74.39	0.00e+00	878.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence