iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062969

UUCD1 version

UUC-MoD-00493

Ensembl Protein ID

ENSMODP00000013062.3

UniProt Accession

F6ZGZ5; F6ZGZ5_MONDO

Protein Name

Uncharacterized protein

Gene Name

ATG16L1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000010423.3	ENSMODT00000013300.3	ENSMODP00000013062.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.50e-32	108.4	423	462
UBD/Beta-Prp	3.80e-61	207.0	334	621

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllks 38
           gH+++v + +f  ++ ++vsGs+D t+k+WDlr+ v++k+
   Q: 423  GHSGKVLSAKFllDNARIVSGSHDRTLKLWDLRSKVCIKT 462
           8***********64489********************985 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk 91
           ++++h++ +++v+fsp+++llatg++d+++k+w+v+   +    slsg +a++t+++f++ g++l+ +s+D + ++w ++++   htl+
   Q: 334  VFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGDRCeaKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDNRLRHTLT 422
           5799*********************************99988899******************************************** PP
   S: 92   ghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgght 180
           gh+ +vls +f  ++ ++vsGshdrt+++wdl+++ c++++++g +    c  + +++++++sG+ D+++r+Wd+++++++r+l+    
   Q: 423  GHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSS----CNDIVCTEQCVMSGHFDKKIRFWDIRSESIIRELE--LL 505
           ***************************************9999988....888888889*************************6..69 PP
   S: 181  dsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght....dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhns 265
           ++++ l++++++++l+s+s+d  +k+ dl+ + + +t+ +      +  ++v  sp++ +++ gs++gs+++W++ +g++ k+l++++s
   Q: 506  GKITALDLNPERTDLLSCSRDDLLKIIDLRVNAVKQTFSAPGfkcgSDWTRVVYSPDGSYVAAGSAEGSLYVWNVLTGKVEKVLSKQHS 594
           ******************************9999888888777777666679999********************************** PP
   S: 266  svisvavlsfgdnvlvlgsedskvniw 292
           s+i   ++s+ + ++v++++ +k+ +w
   Q: 595  SSINAVAWSPCGTHVVSVDKGNKAILW 621
           ****999************98888888 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MSTGLRGSGL PSWKRHIADE LRRRDRLQRQ AFEEIIAQYN KLLEKSDLQS VLADKLQAEK 60
HDLQGRHEIS PGHDGMWNDA QLQEMAQLRI KHQEELTELH KKRGELAQSV IDLNNQMQQK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGACAG GCCTCCGGGG CTCCGGGCTC CCGAGCTGGA AGCGGCACAT CGCGGATGAG 60
CTCCGGCGGC GGGACCGGCT CCAGAGGCAG GCCTTCGAGG AGATCATCGC GCAGTGTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000421--C:autophagosome membrane
GO:0005930--C:axoneme
GO:0000045--P:autophagosome assembly
GO:0039689--P:negative stranded viral RNA replication

KEGG

mdo:100021305

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000090	Aegilops tauschii	27.81	6.00e-33	135.00
IUUC-Aml-002242	Ailuropoda melanoleuca	83.39	0.00e+00	981.00
IUUC-Atr-003073	Amborella trichopoda	28.14	4.00e-26	112.00
IUUC-Apl-003384	Anas platyrhynchos	86.53	0.00e+00	1067.00
IUUC-Aca-004962	Anolis carolinensis	87.18	0.00e+00	1069.00
IUUC-Aly-005435	Arabidopsis lyrata	33.66	2.00e-45	176.00
IUUC-Ath-006948	Arabidopsis thaliana	33.99	1.00e-45	177.00
IUUC-Ame-010915	Astyanax mexicanus	79.14	4.00e-154	537.00
IUUC-Bta-012388	Bos taurus	89.74	0.00e+00	1114.00
IUUC-Bdi-014231	Brachypodium distachyon	28.70	7.00e-38	151.00
IUUC-Bol-016174	Brassica oleracea	34.32	5.00e-46	179.00
IUUC-Bra-017165	Brassica rapa	33.66	3.00e-45	176.00
IUUC-Cel-018131	Caenorhabditis elegans	39.00	1.00e-58	221.00
IUUC-Cja-018898	Callithrix jacchus	77.46	0.00e+00	905.00
IUUC-Cfa-020484	Canis familiaris	87.50	0.00e+00	1080.00
IUUC-Cpo-022156	Cavia porcellus	85.67	0.00e+00	1039.00
IUUC-Csa-024019	Chlorocebus sabaeus	84.62	0.00e+00	1028.00
IUUC-Cho-024311	Choloepus hoffmanni	75.00	0.00e+00	910.00
IUUC-Cin-025260	Ciona intestinalis	35.55	8.00e-96	344.00
IUUC-Csv-025836	Ciona savignyi	44.93	2.00e-48	185.00
IUUC-Dre-027702	Danio rerio	75.04	0.00e+00	913.00
IUUC-Dno-029728	Dasypus novemcinctus	88.78	0.00e+00	1132.00
IUUC-Dor-030587	Dipodomys ordii	77.15	1.00e-112	400.00
IUUC-Dme-031595	Drosophila melanogaster	37.95	1.00e-109	390.00
IUUC-Ete-032969	Echinops telfairi	71.48	0.00e+00	742.00
IUUC-Eca-034214	Equus caballus	88.80	0.00e+00	905.00
IUUC-Eeu-034537	Erinaceus europaeus	83.52	0.00e+00	867.00
IUUC-Fca-036005	Felis catus	90.65	0.00e+00	1047.00
IUUC-Fal-037593	Ficedula albicollis	88.63	0.00e+00	1046.00
IUUC-Gmo-039042	Gadus morhua	63.52	0.00e+00	689.00
IUUC-Gga-040986	Gallus gallus	88.78	0.00e+00	1108.00
IUUC-Gac-041351	Gasterosteus aculeatus	72.92	0.00e+00	915.00
IUUC-Gma-043452	Glycine max	34.53	5.00e-47	182.00
IUUC-Ggo-045427	Gorilla gorilla	89.26	0.00e+00	1084.00
IUUC-Hsa-046632	Homo sapiens	86.54	0.00e+00	1065.00
IUUC-Itr-048504	Ictidomys tridecemlineatus	83.33	0.00e+00	1013.00
IUUC-Lch-049439	Latimeria chalumnae	49.92	3.00e-147	515.00
IUUC-Lpe-051254	Leersia perrieri	29.14	1.00e-37	151.00
IUUC-Loc-052610	Lepisosteus oculatus	76.37	0.00e+00	942.00
IUUC-Laf-053936	Loxodonta africana	88.30	0.00e+00	1075.00
IUUC-Mcc-055504	Macaca mulatta	86.59	0.00e+00	1100.00
IUUC-Meu-056516	Macropus eugenii	90.06	0.00e+00	1082.00
IUUC-Mtr-058062	Medicago truncatula	32.01	8.00e-44	171.00
IUUC-Mga-059777	Meleagris gallopavo	83.95	0.00e+00	1053.00
IUUC-Mmr-061298	Microcebus murinus	90.22	0.00e+00	1090.00
IUUC-Mmu-064076	Mus musculus	88.75	0.00e+00	1069.00
IUUC-Mpu-066196	Mustela putorius furo	90.22	0.00e+00	1091.00
IUUC-Mlu-067651	Myotis lucifugus	85.92	0.00e+00	1054.00
IUUC-Nle-069853	Nomascus leucogenys	85.26	0.00e+00	1046.00
IUUC-Opr-070350	Ochotona princeps	91.67	3.00e-115	409.00
IUUC-Ont-072489	Oreochromis niloticus	74.64	0.00e+00	910.00
IUUC-Oan-072703	Ornithorhynchus anatinus	85.90	0.00e+00	1026.00
IUUC-Ocu-074205	Oryctolagus cuniculus	88.42	0.00e+00	1087.00
IUUC-Oba-075619	Oryza barthii	28.90	1.00e-35	144.00
IUUC-Obr-076632	Oryza brachyantha	28.66	4.00e-37	149.00
IUUC-Ogl-077671	Oryza glaberrima	28.90	1.00e-35	144.00
IUUC-Ogu-078052	Oryza glumaepatula	28.90	1.00e-35	144.00
IUUC-Oin-079611	Oryza indica	28.57	1.00e-33	137.00
IUUC-Olo-080408	Oryza longistaminata	28.90	2.00e-35	143.00
IUUC-Ome-081560	Oryza meridionalis	28.90	8.00e-36	144.00
IUUC-Oni-082145	Oryza nivara	28.90	1.00e-35	144.00
IUUC-Opu-083918	Oryza punctata	28.57	3.00e-35	143.00
IUUC-Oru-084858	Oryza rufipogon	28.57	2.00e-33	136.00
IUUC-Osa-086277	Oryza sativa	28.57	2.00e-33	137.00
IUUC-Ola-086816	Oryzias latipes	72.16	3.00e-105	374.00
IUUC-Olu-087622	Ostreococcus lucimarinus	33.67	4.00e-44	171.00
IUUC-Oga-088765	Otolemur garnettii	82.72	0.00e+00	976.00
IUUC-Oar-090196	Ovis aries	87.81	0.00e+00	980.00
IUUC-Ptr-091676	Pan troglodytes	86.70	0.00e+00	1066.00
IUUC-Pan-092068	Papio anubis	90.06	0.00e+00	1091.00
IUUC-Psi-093367	Pelodiscus sinensis	85.74	0.00e+00	1054.00
IUUC-Ppa-095699	Physcomitrella patens	34.78	9.00e-42	164.00
IUUC-Pfo-096067	Poecilia formosa	72.10	0.00e+00	886.00
IUUC-Pab-098111	Pongo abelii	89.26	0.00e+00	1083.00
IUUC-Pop-099116	Populus trichocarpa	32.25	7.00e-43	168.00
IUUC-Pca-100680	Procavia capensis	79.60	0.00e+00	890.00
IUUC-Ppe-101790	Prunus persica	31.13	5.00e-43	169.00
IUUC-Pva-102871	Pteropus vampyrus	88.23	0.00e+00	1022.00
IUUC-Rno-106088	Rattus norvegicus	87.94	0.00e+00	1058.00
IUUC-Sha-106984	Sarcophilus harrisii	92.09	0.00e+00	1118.00
IUUC-Smo-109404	Selaginella moellendorffii	31.83	8.00e-43	168.00
IUUC-Sit-110828	Setaria italica	31.27	1.00e-40	161.00
IUUC-Sly-111009	Solanum lycopersicum	31.02	3.00e-44	172.00
IUUC-Stu-112370	Solanum tuberosum	31.60	3.00e-45	176.00
IUUC-Sar-113659	Sorex araneus	58.15	1.00e-83	303.00
IUUC-Ssc-116241	Sus scrofa	84.50	0.00e+00	1029.00
IUUC-Tgu-116576	Taeniopygia guttata	86.22	0.00e+00	1097.00
IUUC-Tru-118336	Takifugu rubripes	66.12	0.00e+00	760.00
IUUC-Tsy-119006	Tarsius syrichta	86.54	0.00e+00	1034.00
IUUC-Tni-120300	Tetraodon nigroviridis	74.23	0.00e+00	886.00
IUUC-Tca-121002	Theobroma cacao	32.57	8.00e-46	178.00
IUUC-Tae-124868	Triticum aestivum	28.40	5.00e-34	139.00
IUUC-Tur-126463	Triticum urartu	28.52	2.00e-33	137.00
IUUC-Tbe-127631	Tupaia belangeri	87.65	0.00e+00	867.00
IUUC-Ttr-129005	Tursiops truncatus	80.80	2.00e-156	546.00
IUUC-Vpa-130246	Vicugna pacos	81.22	0.00e+00	812.00
IUUC-Vvi-130878	Vitis vinifera	33.65	2.00e-44	173.00
IUUC-Xtr-132798	Xenopus tropicalis	73.29	0.00e+00	892.00
IUUC-Xma-133264	Xiphophorus maculatus	71.41	0.00e+00	879.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence