iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074459

UUCD1 version

UUC-OrC-01067

Ensembl Protein ID

ENSOCUP00000003802.3

UniProt Accession

G1SLQ6; G1SLQ6_RABIT

Protein Name

Uncharacterized protein

Gene Name

USP30

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000004402.3	ENSOCUT00000004401.3	ENSOCUP00000003802.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.00e-53	180.5	15	379

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 63   skkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..........aeekkkkknksl 141
           +++++ + + ll++l+++  ++s++e+qDa+E+++++ ++le+e    ++ +++++++  + e++++          + + +++  +  
   Q: 15   TDDEVLDASCLLDVLRMYRWQISSFEEQDAHELFHVITSSLEDER--DRQPRVTHLFDVLSLEQPSDatpkritcrtRGSPHPSAPHWK 101
           6677889999**********************************9..6688888888888888887778888888888888999999** PP
   S: 142  isdlFqgqlksqikclecdnvs.sreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekck...............kk 214
            ++ F+g+l+s+++c++c+++s +r+++f +lsl++p  +  ++++l++cL++f + e++++   + c++c+               ++
   Q: 102  SQHPFHGRLTSNMVCKHCEHQSpVRFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRD---VVCDNCTrleakgtldgaevehQR 187
           ************************************************************97...9******77777777777777666 PP
   S: 215  qeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts....................peekqke......... 274
           ++ +k+lkl klP++L++hL+R s+s++ + + k +++v+f++ L ++ +  +                          +         
   Q: 188  TTFVKQLKLGKLPQCLCIHLQRLSWSSH-GTPLKRHEHVQFNEFLMMDIYKYRllghkarqhkpehsespgpaL-----Dlpgpkavls 270
           66***********************998.8888*********88888866666556666666655555555550.....0555555555 PP
   S: 275  ........................................kkkYeLiavvvHsGslssGHYvayvkn.........ekgkWllfdDskV 314
                                                   ++ ++L+avvvH+G ++sGH+v+y ++         ++ +Wl ++D++V
   Q: 271  ppgapktqvflngacapallpplpapmpfplpvipdysssTYLFRLMAVVVHHGDMHSGHFVTYRRSppsaknplaTSSQWLWVSDDTV 359
           55555555566666666666666666666666666666559999***********************9988888877888********* PP
   S: 315  tevkeeevleetgstaYvlfYkr 337
           ++ + +evl+   ++aY+lfY+r
   Q: 360  RKASLQEVLS---CSAYLLFYER 379
           **********...********98 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MRESSSQALS GQEVTDDEVL DASCLLDVLR MYRWQISSFE EQDAHELFHV ITSSLEDERD 60
RQPRVTHLFD VLSLEQPSDA TPKRITCRTR GSPHPSAPHW KSQHPFHGRL TSNMVCKHCE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAAGGCAGA GAGAGAGAGA AGAGACAGGG ATCATCTACT GGTTCACTTC CCAGATGGCC 60
TCAACAGCCA GGCCTGAGGC AGGCCAAAGC TGGGAGCCAG GAGCTTCTTC TGGGTCTCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005741--C:mitochondrial outer membrane
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008053--P:mitochondrial fusion
GO:0000422--P:mitophagy
GO:0035871--P:protein K11-linked deubiquitination
GO:0044313--P:protein K6-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001733	Ailuropoda melanoleuca	85.24	0.00e+00	645.00
IUUC-Atr-002510	Amborella trichopoda	29.30	4.00e-11	62.80
IUUC-Apl-003645	Anas platyrhynchos	67.03	2.00e-95	341.00
IUUC-Aca-004583	Anolis carolinensis	67.11	5.00e-24	101.00
IUUC-Ame-010896	Astyanax mexicanus	57.73	2.00e-122	432.00
IUUC-Bta-012321	Bos taurus	84.62	0.00e+00	644.00
IUUC-Cel-018308	Caenorhabditis elegans	26.36	1.00e-23	104.00
IUUC-Cja-018826	Callithrix jacchus	86.70	0.00e+00	668.00
IUUC-Cfa-021206	Canis familiaris	86.77	0.00e+00	654.00
IUUC-Cpo-021343	Cavia porcellus	84.87	0.00e+00	651.00
IUUC-Csa-023419	Chlorocebus sabaeus	87.69	0.00e+00	672.00
IUUC-Cho-024475	Choloepus hoffmanni	83.27	5.00e-127	447.00
IUUC-Cne-027061	Cryptococcus neoformans	28.40	6.00e-07	49.70
IUUC-Dre-027563	Danio rerio	53.67	3.00e-118	418.00
IUUC-Dno-029929	Dasypus novemcinctus	85.64	0.00e+00	659.00
IUUC-Dor-030166	Dipodomys ordii	80.39	6.00e-159	553.00
IUUC-Dme-031627	Drosophila melanogaster	37.04	3.00e-21	96.30
IUUC-Ete-032634	Echinops telfairi	78.24	7.00e-153	533.00
IUUC-Eca-033968	Equus caballus	86.67	0.00e+00	657.00
IUUC-Eeu-035279	Erinaceus europaeus	81.45	7.00e-42	164.00
IUUC-Fca-036525	Felis catus	86.67	0.00e+00	660.00
IUUC-Fal-036606	Ficedula albicollis	74.28	6.00e-119	420.00
IUUC-Gmo-038726	Gadus morhua	54.21	6.00e-114	404.00
IUUC-Gga-040718	Gallus gallus	82.77	1.00e-118	419.00
IUUC-Gac-042645	Gasterosteus aculeatus	57.49	7.00e-118	417.00
IUUC-Gma-042890	Glycine max	23.53	1.00e-19	91.30
IUUC-Ggo-045021	Gorilla gorilla	87.95	0.00e+00	669.00
IUUC-Hsa-045832	Homo sapiens	87.95	0.00e+00	669.00
IUUC-Itr-048392	Ictidomys tridecemlineatus	87.69	0.00e+00	669.00
IUUC-Lch-050662	Latimeria chalumnae	66.04	3.00e-139	488.00
IUUC-Lpe-051640	Leersia perrieri	50.00	3.00e-13	70.90
IUUC-Loc-052611	Lepisosteus oculatus	64.21	3.00e-140	491.00
IUUC-Lma-053048	Leptosphaeria maculans	20.68	1.00e-08	55.50
IUUC-Laf-053752	Loxodonta africana	87.18	0.00e+00	654.00
IUUC-Mcc-054892	Macaca mulatta	88.21	0.00e+00	673.00
IUUC-Meu-056673	Macropus eugenii	70.50	1.00e-146	512.00
IUUC-Mtr-057976	Medicago truncatula	22.49	8.00e-20	92.00
IUUC-Mla-058970	Melampsora laricipopulina	21.76	9.00e-16	78.60
IUUC-Mga-059543	Meleagris gallopavo	71.43	5.00e-153	533.00
IUUC-Mmr-061534	Microcebus murinus	88.46	0.00e+00	669.00
IUUC-Mdo-062140	Monodelphis domestica	62.38	2.00e-122	432.00
IUUC-Mmu-063673	Mus musculus	85.13	0.00e+00	653.00
IUUC-Mpu-066328	Mustela putorius furo	85.64	0.00e+00	652.00
IUUC-Mlu-067938	Myotis lucifugus	86.92	0.00e+00	656.00
IUUC-Nle-069426	Nomascus leucogenys	87.44	0.00e+00	661.00
IUUC-Opr-070796	Ochotona princeps	88.33	5.00e-122	431.00
IUUC-Ont-072248	Oreochromis niloticus	58.42	1.00e-118	419.00
IUUC-Oan-072916	Ornithorhynchus anatinus	76.41	1.00e-164	573.00
IUUC-Obr-076005	Oryza brachyantha	26.65	2.00e-23	103.00
IUUC-Ogl-077916	Oryza glaberrima	27.42	2.00e-15	77.40
IUUC-Ogu-078263	Oryza glumaepatula	26.02	3.00e-21	96.70
IUUC-Ola-087429	Oryzias latipes	58.08	4.00e-112	398.00
IUUC-Oga-087981	Otolemur garnettii	87.69	0.00e+00	656.00
IUUC-Oar-089927	Ovis aries	85.13	0.00e+00	646.00
IUUC-Ptr-090878	Pan troglodytes	87.95	0.00e+00	669.00
IUUC-Pan-092698	Papio anubis	88.21	0.00e+00	673.00
IUUC-Psi-093451	Pelodiscus sinensis	70.66	1.00e-155	542.00
IUUC-Pfo-096096	Poecilia formosa	60.75	2.00e-119	422.00
IUUC-Pab-098676	Pongo abelii	86.15	0.00e+00	649.00
IUUC-Pca-100418	Procavia capensis	91.36	7.00e-84	304.00
IUUC-Pva-103018	Pteropus vampyrus	84.36	0.00e+00	638.00
IUUC-Ptt-103779	Puccinia triticina	20.09	1.00e-11	65.10
IUUC-Pte-104330	Pyrenophora teres	21.96	2.00e-09	57.80
IUUC-Pyt-104518	Pyrenophora triticirepentis	21.50	9.00e-13	68.90
IUUC-Rno-105708	Rattus norvegicus	84.54	0.00e+00	647.00
IUUC-Sha-106971	Sarcophilus harrisii	75.06	4.00e-168	584.00
IUUC-Sit-110442	Setaria italica	26.24	4.00e-18	85.90
IUUC-Stu-112223	Solanum tuberosum	22.86	8.00e-14	71.20
IUUC-Ssc-116397	Sus scrofa	83.59	0.00e+00	633.00
IUUC-Tgu-117446	Taeniopygia guttata	68.23	7.00e-147	513.00
IUUC-Tru-118268	Takifugu rubripes	57.33	4.00e-108	385.00
IUUC-Tsy-119484	Tarsius syrichta	84.25	1.00e-47	184.00
IUUC-Tni-119735	Tetraodon nigroviridis	57.07	2.00e-107	382.00
IUUC-Tae-125203	Triticum aestivum	27.08	1.00e-21	97.40
IUUC-Tbe-127740	Tupaia belangeri	80.00	7.00e-170	590.00
IUUC-Ttr-129273	Tursiops truncatus	84.10	0.00e+00	636.00
IUUC-Vvi-131177	Vitis vinifera	26.48	3.00e-13	70.10
IUUC-Xtr-132374	Xenopus tropicalis	62.47	4.00e-133	468.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence