iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020066

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03014749

Gene Name

UBE3B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000010870.3	ENSCAFT00000017297.3	ENSCAFP00000016008.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	9.20e-108	360.9	703	1056

Active Site

Position(s)	Description	Evidence
1036	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           ++++k +++v+fv+     E+g+d++Gv++efl++++k++++p l+lf+++++d++ l+p+p+s++++ ++l+lFef+G++lgka++
   Q: 703  QHAMKGVIRVKFVNdlgvdEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDER-LYPSPTSYIHE-NYLQLFEFVGKMLGKAVY 787
           7899********************************************99987665.59*******76.****************** PP
   S: 84   dgrlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           +g ++d+p++++f+++llg+       s+++l+++d+e+yk+l++ik++ + di +lgl+l++  +e+++g+  ++eL+pgG++ipV
   Q: 788  EGIVVDVPFASFFLSQLLGHhhsifYSSVDELPSLDSEFYKNLTSIKRY-DGDIADLGLTLSY--DEDVMGQLVCHELIPGGKTIPV 871
           ********************777777999********************.6788887777766..6999****************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwe 251
           tneNk +Y++l++++r++++ik+q++a+ +Gf+++i++e+ ++F++ el+ li+G+ +eid+edlkk+t y gg++ ++++i+w+w+
   Q: 872  TNENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWTRMFSTPELQRLISGDnAEIDLEDLKKHTVYYGGFHGSHRVIIWLWD 958
           ********************************************************9****************************** PP
   S: 252  vl.eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirkdasddrlPssnTCfnyLkLPeY 313
           +l ++f+ +er++fL+FvT++sr Pl Gfa+lk                        + +f+irk +   rlP+s+TCfn+LkLP+Y
   Q: 959  ILaSDFTPDERAMFLKFVTSCSRPPLLGFAYLKppfsircvevsddqdtgdtlgsvlRGFFTIRKREPGGRLPTSSTCFNLLKLPNY 1045
           **99*************************************************************8888****************** PP
   S: 314  sskeilkekLl 324
           s+k++l+ekL 
   Q: 1046 SKKSVLREKLS 1056
           *********95 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MFTVSQTSRA WFIDRARQAR EERLVQKERE RAAVEIQAHV RSFLCRSRLQ REIRREIDEY 60
FKADDAEASK RSALCIFKIA RKLLFLFRIK EDNERFEKLC RCILSSMEAE NEPKVWYVSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAAACCTCAC GCCATATATA TCAAGGAAAA AAAGAGAAAG GACACAAATA AATAAAACCA 60
TAAATAAATG AGAAACACCC AGCTCGCGCA AGCGGGGGGC AGAGGCGGGC CCGGGGCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS
IPR027401--Myosin-like_IQ_dom

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	35.17	2.00e-99	357.00
IUUC-Aml-002107	Ailuropoda melanoleuca	98.49	0.00e+00	2115.00
IUUC-Atr-003017	Amborella trichopoda	37.39	4.00e-104	373.00
IUUC-Apl-003328	Anas platyrhynchos	88.37	0.00e+00	1841.00
IUUC-Aly-005794	Arabidopsis lyrata	38.21	1.00e-103	371.00
IUUC-Ath-007269	Arabidopsis thaliana	38.57	2.00e-106	380.00
IUUC-Bta-013547	Bos taurus	96.22	0.00e+00	2093.00
IUUC-Bdi-014502	Brachypodium distachyon	37.89	2.00e-103	370.00
IUUC-Bol-015093	Brassica oleracea	39.31	1.00e-107	384.00
IUUC-Bra-016722	Brassica rapa	39.12	6.00e-108	385.00
IUUC-Cel-018447	Caenorhabditis elegans	37.30	0.00e+00	665.00
IUUC-Cja-019855	Callithrix jacchus	96.50	0.00e+00	2069.00
IUUC-Cpo-021504	Cavia porcellus	95.08	0.00e+00	2061.00
IUUC-Csa-023579	Chlorocebus sabaeus	96.50	0.00e+00	2073.00
IUUC-Cho-024430	Choloepus hoffmanni	86.54	0.00e+00	1562.00
IUUC-Cin-025750	Ciona intestinalis	46.71	0.00e+00	951.00
IUUC-Csv-026016	Ciona savignyi	47.88	0.00e+00	1008.00
IUUC-Dre-028271	Danio rerio	81.49	0.00e+00	1742.00
IUUC-Dno-029054	Dasypus novemcinctus	96.69	0.00e+00	2076.00
IUUC-Dor-030938	Dipodomys ordii	87.61	0.00e+00	1846.00
IUUC-Dme-031602	Drosophila melanogaster	48.18	0.00e+00	948.00
IUUC-Ete-033041	Echinops telfairi	76.71	0.00e+00	1378.00
IUUC-Eca-034411	Equus caballus	97.16	0.00e+00	2065.00
IUUC-Eeu-035201	Erinaceus europaeus	85.56	0.00e+00	812.00
IUUC-Fca-036594	Felis catus	96.23	0.00e+00	2057.00
IUUC-Fal-037317	Ficedula albicollis	84.60	0.00e+00	1849.00
IUUC-Gmo-039412	Gadus morhua	77.51	0.00e+00	1704.00
IUUC-Gga-040149	Gallus gallus	88.48	0.00e+00	1878.00
IUUC-Gac-042088	Gasterosteus aculeatus	80.66	0.00e+00	1799.00
IUUC-Gma-042728	Glycine max	39.82	1.00e-105	378.00
IUUC-Ggo-045279	Gorilla gorilla	96.59	0.00e+00	2076.00
IUUC-Hsa-045660	Homo sapiens	96.31	0.00e+00	2070.00
IUUC-Hvu-047102	Hordeum vulgare	34.93	3.00e-99	357.00
IUUC-Itr-048021	Ictidomys tridecemlineatus	94.14	0.00e+00	1061.00
IUUC-Lch-050664	Latimeria chalumnae	82.14	0.00e+00	1810.00
IUUC-Loc-052791	Lepisosteus oculatus	82.78	0.00e+00	1769.00
IUUC-Laf-053902	Loxodonta africana	96.88	0.00e+00	2083.00
IUUC-Mcc-054730	Macaca mulatta	96.40	0.00e+00	2072.00
IUUC-Meu-056527	Macropus eugenii	79.74	0.00e+00	1660.00
IUUC-Mtr-057671	Medicago truncatula	38.91	6.00e-106	379.00
IUUC-Mga-059260	Meleagris gallopavo	88.12	0.00e+00	1875.00
IUUC-Mmr-060804	Microcebus murinus	94.61	0.00e+00	1986.00
IUUC-Mdo-062575	Monodelphis domestica	83.58	0.00e+00	1768.00
IUUC-Mmu-063636	Mus musculus	91.12	0.00e+00	1915.00
IUUC-Mac-064989	Musa acuminata	38.29	4.00e-101	363.00
IUUC-Mpu-066677	Mustela putorius furo	98.21	0.00e+00	2003.00
IUUC-Mlu-067952	Myotis lucifugus	96.31	0.00e+00	1997.00
IUUC-Nle-069153	Nomascus leucogenys	96.50	0.00e+00	2071.00
IUUC-Opr-070554	Ochotona princeps	94.01	0.00e+00	1848.00
IUUC-Ont-071372	Oreochromis niloticus	81.85	0.00e+00	1779.00
IUUC-Oan-073327	Ornithorhynchus anatinus	71.59	0.00e+00	748.00
IUUC-Ocu-074183	Oryctolagus cuniculus	94.81	0.00e+00	2019.00
IUUC-Oba-075213	Oryza barthii	37.59	3.00e-100	360.00
IUUC-Obr-076320	Oryza brachyantha	38.18	6.00e-103	369.00
IUUC-Ogl-077093	Oryza glaberrima	37.77	6.00e-103	369.00
IUUC-Oin-080058	Oryza indica	37.86	1.00e-102	368.00
IUUC-Olo-080742	Oryza longistaminata	37.59	9.00e-102	365.00
IUUC-Ome-081741	Oryza meridionalis	37.29	3.00e-95	343.00
IUUC-Opu-083529	Oryza punctata	37.77	1.00e-102	368.00
IUUC-Oru-085128	Oryza rufipogon	37.18	3.00e-95	343.00
IUUC-Osa-085557	Oryza sativa	37.86	3.00e-102	366.00
IUUC-Ola-087337	Oryzias latipes	81.00	0.00e+00	1714.00
IUUC-Oga-088342	Otolemur garnettii	95.56	0.00e+00	1965.00
IUUC-Oar-090234	Ovis aries	95.62	0.00e+00	2107.00
IUUC-Ptr-091661	Pan troglodytes	96.59	0.00e+00	2076.00
IUUC-Pan-092728	Papio anubis	96.22	0.00e+00	2066.00
IUUC-Psi-093251	Pelodiscus sinensis	88.38	0.00e+00	1770.00
IUUC-Pma-094195	Petromyzon marinus	69.82	0.00e+00	1434.00
IUUC-Pfo-097472	Poecilia formosa	81.29	0.00e+00	1782.00
IUUC-Pab-098570	Pongo abelii	96.40	0.00e+00	2072.00
IUUC-Pca-100110	Procavia capensis	83.73	0.00e+00	1732.00
IUUC-Ppe-101281	Prunus persica	38.11	1.00e-101	364.00
IUUC-Pva-102887	Pteropus vampyrus	91.87	0.00e+00	1941.00
IUUC-Rno-106028	Rattus norvegicus	88.11	0.00e+00	1818.00
IUUC-Sha-107331	Sarcophilus harrisii	84.79	0.00e+00	1801.00
IUUC-Sit-109811	Setaria italica	34.78	2.00e-104	374.00
IUUC-Sly-111013	Solanum lycopersicum	39.03	1.00e-102	367.00
IUUC-Sar-113287	Sorex araneus	85.95	0.00e+00	738.00
IUUC-Sbi-114433	Sorghum bicolor	34.30	5.00e-104	372.00
IUUC-Ssc-116103	Sus scrofa	97.26	0.00e+00	2059.00
IUUC-Tgu-117275	Taeniopygia guttata	87.72	0.00e+00	1858.00
IUUC-Tru-118681	Takifugu rubripes	80.34	0.00e+00	1790.00
IUUC-Tsy-118985	Tarsius syrichta	91.55	0.00e+00	1044.00
IUUC-Tni-120850	Tetraodon nigroviridis	90.72	0.00e+00	749.00
IUUC-Tca-121770	Theobroma cacao	37.97	5.00e-105	375.00
IUUC-Tae-125466	Triticum aestivum	35.99	9.00e-103	368.00
IUUC-Tur-126086	Triticum urartu	38.36	6.00e-99	355.00
IUUC-Tbe-127461	Tupaia belangeri	91.58	0.00e+00	1885.00
IUUC-Ttr-129269	Tursiops truncatus	96.69	0.00e+00	2044.00
IUUC-Vpa-130523	Vicugna pacos	77.96	1.00e-130	461.00
IUUC-Vvi-131524	Vitis vinifera	38.32	9.00e-104	372.00
IUUC-Xtr-132146	Xenopus tropicalis	83.57	0.00e+00	1826.00
IUUC-Xma-133526	Xiphophorus maculatus	81.10	0.00e+00	1776.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence