iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nle-069025

Ensembl Protein ID

ENSNLEP00000019767.1

UniProt Accession

G1S2M9; G1S2M9_NOMLE

Genbank Protein ID

ENSNLEP00000019767

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01185176

Gene Name

FAF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000016263.2	ENSNLET00000020761.2	ENSNLEP00000019767.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	2.80e-07	30.4	5	45
ULD/UDP/UFD/UBX	8.40e-20	71.1	569	646
ULD/UDP/UBQ/UBQ_Other	2.70e-10	40.0	111	170

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 1    sededkleqlve.MGF.dreealqaLraannnleaAveyLl 39
           +++e++l+ + + +G+ + +ea++ L+++n++l aA++ ++
   Q: 5    MDREMILADFHAcTGIeNIDEAITLLEQNNWDLVAAINGVI 45
           689**********************************9875 PP

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfveyllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllve 80
           +++ ++l+iR+p+G++l+r+F +s++l+ +++fv+ ++++++d+++L+s+fPrr++++ + +++l e +L+p+++l++e
   Q: 569  AEPVSKLRIRTPSGEFLERRFLASNKLQIVFDFVA-SKGFPWDEYKLLSTFPRRDVTQLDPNKSLLEVKLFPQETLFLE 646
           56799******************************.****************************************986 PP

ULD/UDP/UBQ/UBQ_Other

   S: 12   eltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL...eddktLadyglkdgstihll 70
           + ++ ++ s+tV+e+K+ +e +l ip   +++++kG      ed   L++++l+ ++ +++l
   Q: 111  NVDVVLEDSCTVGEIKQILENELQIP--VSKMLLKGWKTgdvEDSTVLKSLHLPKNNSLYVL 170
           5566678999****************..55899997776777***************99987 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MASNMDREMI LADFHACTGI ENIDEAITLL EQNNWDLVAA INGVIPQENG ILQSEYGGET 60
IPGPAFNPAS HPASAPTSSS SSAFRPVMPS RQIVERQPRM LDFRVEYRDR NVDVVLEDSC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGGGCGGA GGCGGCGGCC AGGGAGGAAG CGGAGGAGGC GGAGGCGGCC GCGGCGTTCG 60
CCCGCCCGCT CGCTCTCTCG GTTTCCCCGC CCCCGCCGGG CTTAACGCCG CTGAAGGTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033043--FAF1_UBX
IPR012336--Thioredoxin-like_fold
IPR006577--UAS
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50033--UBX

Pfam

PF00789--UBX

SMART

SM00594--UAS
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0008219--P:cell death
GO:0007253--P:cytoplasmic sequestering of NF-kappaB
GO:0010942--P:positive regulation of cell death
GO:0031334--P:positive regulation of protein complex assembly
GO:0042176--P:regulation of protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002153	Ailuropoda melanoleuca	97.38	0.00e+00	1214.00
IUUC-Apl-004127	Anas platyrhynchos	90.75	0.00e+00	1126.00
IUUC-Aca-005188	Anolis carolinensis	89.95	0.00e+00	1117.00
IUUC-Ame-010696	Astyanax mexicanus	77.15	0.00e+00	860.00
IUUC-Bta-012965	Bos taurus	97.38	0.00e+00	1219.00
IUUC-Cel-018420	Caenorhabditis elegans	29.12	1.00e-29	124.00
IUUC-Cja-019128	Callithrix jacchus	97.55	0.00e+00	1238.00
IUUC-Cfa-021201	Canis familiaris	96.46	0.00e+00	900.00
IUUC-Cpo-021475	Cavia porcellus	95.83	0.00e+00	896.00
IUUC-Csa-024076	Chlorocebus sabaeus	97.38	0.00e+00	1228.00
IUUC-Cho-025067	Choloepus hoffmanni	83.38	0.00e+00	1055.00
IUUC-Cin-025663	Ciona intestinalis	44.35	6.00e-69	254.00
IUUC-Csv-025894	Ciona savignyi	34.76	1.00e-70	260.00
IUUC-Dre-027508	Danio rerio	74.66	0.00e+00	931.00
IUUC-Dno-029336	Dasypus novemcinctus	96.77	0.00e+00	1200.00
IUUC-Dor-030218	Dipodomys ordii	88.62	0.00e+00	1091.00
IUUC-Dme-031581	Drosophila melanogaster	32.91	3.00e-94	339.00
IUUC-Ete-032860	Echinops telfairi	75.78	0.00e+00	671.00
IUUC-Eca-034321	Equus caballus	98.22	0.00e+00	1051.00
IUUC-Eeu-034844	Erinaceus europaeus	75.20	7.00e-145	507.00
IUUC-Fca-036575	Felis catus	98.67	0.00e+00	726.00
IUUC-Fal-037128	Ficedula albicollis	91.09	0.00e+00	1147.00
IUUC-Gmo-038694	Gadus morhua	73.97	0.00e+00	894.00
IUUC-Gga-040826	Gallus gallus	91.40	0.00e+00	1155.00
IUUC-Gac-042125	Gasterosteus aculeatus	74.92	0.00e+00	961.00
IUUC-Ggo-045254	Gorilla gorilla	99.23	0.00e+00	1236.00
IUUC-Hsa-046722	Homo sapiens	99.08	0.00e+00	1235.00
IUUC-Itr-048149	Ictidomys tridecemlineatus	97.70	5.00e-101	359.00
IUUC-Lch-050312	Latimeria chalumnae	80.58	0.00e+00	659.00
IUUC-Loc-051990	Lepisosteus oculatus	81.25	0.00e+00	956.00
IUUC-Laf-054375	Loxodonta africana	98.14	0.00e+00	724.00
IUUC-Mcc-054627	Macaca mulatta	99.06	0.00e+00	1204.00
IUUC-Meu-056611	Macropus eugenii	72.59	6.00e-131	461.00
IUUC-Mga-059400	Meleagris gallopavo	89.25	0.00e+00	1131.00
IUUC-Mvi-060242	Microbotryum violaceum	26.39	8.10e-02	31.20
IUUC-Mmr-060882	Microcebus murinus	97.38	0.00e+00	1186.00
IUUC-Mdo-061874	Monodelphis domestica	91.69	0.00e+00	1168.00
IUUC-Mmu-063444	Mus musculus	94.77	0.00e+00	1208.00
IUUC-Mpu-065713	Mustela putorius furo	96.22	0.00e+00	1178.00
IUUC-Mlu-068122	Myotis lucifugus	96.11	0.00e+00	1155.00
IUUC-Opr-071089	Ochotona princeps	85.85	0.00e+00	1088.00
IUUC-Ont-072421	Oreochromis niloticus	74.55	0.00e+00	943.00
IUUC-Oan-073092	Ornithorhynchus anatinus	88.48	0.00e+00	846.00
IUUC-Ola-086497	Oryzias latipes	75.56	0.00e+00	952.00
IUUC-Oga-088854	Otolemur garnettii	95.85	0.00e+00	1207.00
IUUC-Oar-090120	Ovis aries	97.54	0.00e+00	1197.00
IUUC-Ptr-091554	Pan troglodytes	99.23	0.00e+00	1236.00
IUUC-Pan-091985	Papio anubis	98.92	0.00e+00	1207.00
IUUC-Psi-093548	Pelodiscus sinensis	91.19	0.00e+00	1085.00
IUUC-Pma-094123	Petromyzon marinus	52.94	3.00e-51	194.00
IUUC-Pfo-096729	Poecilia formosa	74.04	0.00e+00	940.00
IUUC-Pab-097810	Pongo abelii	99.38	0.00e+00	1239.00
IUUC-Pca-101079	Procavia capensis	89.37	0.00e+00	896.00
IUUC-Pva-102534	Pteropus vampyrus	89.05	0.00e+00	922.00
IUUC-Rno-105127	Rattus norvegicus	94.30	0.00e+00	1093.00
IUUC-Sha-106667	Sarcophilus harrisii	92.74	0.00e+00	1021.00
IUUC-Ssl-108656	Sclerotinia sclerotiorum	24.63	1.20e-02	33.10
IUUC-Sar-113424	Sorex araneus	82.60	0.00e+00	645.00
IUUC-Ssc-115974	Sus scrofa	97.32	0.00e+00	1167.00
IUUC-Tgu-116495	Taeniopygia guttata	91.09	0.00e+00	1149.00
IUUC-Tru-118727	Takifugu rubripes	72.90	0.00e+00	922.00
IUUC-Tsy-118906	Tarsius syrichta	91.23	0.00e+00	1100.00
IUUC-Tni-119717	Tetraodon nigroviridis	76.23	0.00e+00	942.00
IUUC-Tbe-127849	Tupaia belangeri	82.26	0.00e+00	718.00
IUUC-Ttr-128660	Tursiops truncatus	92.94	0.00e+00	1148.00
IUUC-Vpa-130359	Vicugna pacos	97.80	0.00e+00	1197.00
IUUC-Xtr-132212	Xenopus tropicalis	86.18	0.00e+00	710.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence