iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-116355

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

E3 ubiquitin-protein ligase TRIM13

Genbank Nucleotide ID

GACC01000004

Gene Name

TRIM13

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000009389.2	ENSSSCT00000010288.2	ENSSSCP00000010020.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.10e-09	36.0	10	58

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw....pglknssskefrCPlCr 46
           C+iC++ f+d p+vlpC H f+++Cl+ +    +  +   s  f+CP+Cr
   Q: 10   CPICCSLFDD-PRVLPCSHNFCKKCLEGLlegnVRNSLWRSSPFKCPTCR 58
           ********99.**************966666666666679999******8 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MELLEEDLTC PICCSLFDDP RVLPCSHNFC KKCLEGLLEG NVRNSLWRSS PFKCPTCRKE 60
TSATGVNSLQ VNYSLKGIVE KYNKIKISPK MPVCKGHLGQ PLNIFCLTDM QLICGICATR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCAGTAGCC TTGTCTGATT ACCAGTAACG ACAAGAAGAA AAAAGAAAGA ACAAAACCCG 60
ATTGCTTTGC CCTGGGAAGT AGTAATCCTG ACCAATACAC CTGCTTGCAA GAGACAGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0097038--C:perinuclear endoplasmic reticulum
GO:0016874--F:ligase activity
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0010942--P:positive regulation of cell death
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016239--P:positive regulation of macroautophagy
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0051865--P:protein autoubiquitination
GO:0010332--P:response to gamma radiation
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

ssc:100153839

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002269	Ailuropoda melanoleuca	95.82	0.00e+00	746.00
IUUC-Apl-004168	Anas platyrhynchos	76.23	0.00e+00	635.00
IUUC-Aca-004395	Anolis carolinensis	70.34	2.00e-168	585.00
IUUC-Ame-011325	Astyanax mexicanus	46.44	3.00e-68	251.00
IUUC-Bta-012613	Bos taurus	96.07	0.00e+00	749.00
IUUC-Cja-018856	Callithrix jacchus	93.61	0.00e+00	794.00
IUUC-Cfa-021019	Canis familiaris	94.35	0.00e+00	738.00
IUUC-Cpo-021845	Cavia porcellus	92.63	0.00e+00	730.00
IUUC-Csa-023380	Chlorocebus sabaeus	92.87	0.00e+00	739.00
IUUC-Cho-024733	Choloepus hoffmanni	86.43	7.00e-94	337.00
IUUC-Dre-028675	Danio rerio	48.66	9.00e-110	389.00
IUUC-Dno-030018	Dasypus novemcinctus	93.14	0.00e+00	751.00
IUUC-Dor-030599	Dipodomys ordii	91.76	9.00e-134	468.00
IUUC-Ete-033134	Echinops telfairi	89.22	0.00e+00	731.00
IUUC-Eca-033931	Equus caballus	96.31	0.00e+00	741.00
IUUC-Eeu-034903	Erinaceus europaeus	92.63	0.00e+00	727.00
IUUC-Fca-035642	Felis catus	95.82	0.00e+00	737.00
IUUC-Fal-037108	Ficedula albicollis	76.96	0.00e+00	650.00
IUUC-Gga-040903	Gallus gallus	75.50	0.00e+00	631.00
IUUC-Ggo-044635	Gorilla gorilla	93.37	0.00e+00	743.00
IUUC-Hsa-046345	Homo sapiens	93.12	0.00e+00	742.00
IUUC-Itr-048220	Ictidomys tridecemlineatus	92.44	0.00e+00	711.00
IUUC-Lch-050599	Latimeria chalumnae	60.55	3.00e-138	484.00
IUUC-Loc-052378	Lepisosteus oculatus	63.07	2.00e-117	415.00
IUUC-Laf-053332	Loxodonta africana	93.14	0.00e+00	733.00
IUUC-Mcc-054705	Macaca mulatta	92.63	0.00e+00	738.00
IUUC-Meu-056825	Macropus eugenii	85.05	0.00e+00	719.00
IUUC-Mga-059528	Meleagris gallopavo	75.49	0.00e+00	643.00
IUUC-Mmr-060688	Microcebus murinus	94.84	0.00e+00	741.00
IUUC-Mdo-061882	Monodelphis domestica	84.07	0.00e+00	722.00
IUUC-Mmu-064352	Mus musculus	90.42	0.00e+00	751.00
IUUC-Mpu-066712	Mustela putorius furo	95.78	0.00e+00	687.00
IUUC-Mlu-068093	Myotis lucifugus	93.61	0.00e+00	724.00
IUUC-Nle-069310	Nomascus leucogenys	93.37	0.00e+00	741.00
IUUC-Ont-071759	Oreochromis niloticus	59.93	5.00e-112	397.00
IUUC-Oan-073673	Ornithorhynchus anatinus	81.13	0.00e+00	699.00
IUUC-Ocu-074192	Oryctolagus cuniculus	94.59	0.00e+00	749.00
IUUC-Ola-087424	Oryzias latipes	59.61	1.00e-110	392.00
IUUC-Oga-088808	Otolemur garnettii	94.10	0.00e+00	746.00
IUUC-Oar-089553	Ovis aries	96.07	0.00e+00	748.00
IUUC-Ptr-090518	Pan troglodytes	92.87	0.00e+00	739.00
IUUC-Pan-092781	Papio anubis	92.38	0.00e+00	736.00
IUUC-Psi-093914	Pelodiscus sinensis	75.31	0.00e+00	637.00
IUUC-Pfo-096346	Poecilia formosa	49.15	4.00e-111	394.00
IUUC-Pca-100914	Procavia capensis	91.18	0.00e+00	748.00
IUUC-Pva-102728	Pteropus vampyrus	94.84	0.00e+00	738.00
IUUC-Rno-105922	Rattus norvegicus	89.19	0.00e+00	687.00
IUUC-Sha-107124	Sarcophilus harrisii	84.80	0.00e+00	730.00
IUUC-Sar-113607	Sorex araneus	89.68	0.00e+00	699.00
IUUC-Tgu-116476	Taeniopygia guttata	76.72	0.00e+00	647.00
IUUC-Tru-118737	Takifugu rubripes	60.26	4.00e-113	400.00
IUUC-Tsy-118908	Tarsius syrichta	94.10	0.00e+00	761.00
IUUC-Tbe-127258	Tupaia belangeri	96.56	0.00e+00	752.00
IUUC-Vpa-130138	Vicugna pacos	96.31	0.00e+00	756.00
IUUC-Xtr-132100	Xenopus tropicalis	59.76	2.00e-136	478.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence