iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071524

Ensembl Protein ID

ENSONIP00000019769.1

UniProt Accession

I3KF74; I3KF74_ORENI

Genbank Protein ID

ENSONIP00000019769

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AERX01061734

Gene Name

ing2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000015708.1	ENSONIT00000019786.1	ENSONIP00000019769.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.10e-08	35.5	221	267

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C++ + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr
   Q: 221  TYC-LCEQVSYGE--MIGCDNdqCPiEWFHFSCVGLT---YKPKGK-WYCPKCR 267
           69*.*******99..*****999*99***********...888886.******8 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

LPLCILETML GHHFPNADKS QQLVNYVEDY LECVESLPLD IQRNVSLLRE IDAKYQDVLN 60
EVDEVFEKYK GEQDGAQRKR LQIQLQRALI ISQELGDEKI HVVTQMTELV ENRSRQMDSH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACTTTTTGC CTCTATGCAT CTTAGAGACG ATGTTAGGCC ACCATTTCCC AAATGCCGAC 60
AAGTCGCAAC AACTGGTCAA CTATGTGGAG GATTATCTGG AATGTGTGGA GTCGCTGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0042981--P:regulation of apoptotic process
GO:2000772--P:regulation of cellular senescence

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002213	Ailuropoda melanoleuca	64.84	2.00e-77	281.00
IUUC-Aca-004990	Anolis carolinensis	66.54	1.00e-81	296.00
IUUC-Ame-011426	Astyanax mexicanus	68.09	2.00e-89	321.00
IUUC-Bta-012721	Bos taurus	65.57	2.00e-76	279.00
IUUC-Cja-018960	Callithrix jacchus	66.18	1.00e-69	256.00
IUUC-Cfa-020869	Canis familiaris	64.84	5.00e-77	280.00
IUUC-Cpo-021414	Cavia porcellus	64.47	1.00e-76	279.00
IUUC-Csa-023304	Chlorocebus sabaeus	66.30	3.00e-70	258.00
IUUC-Dre-028562	Danio rerio	73.50	2.00e-98	351.00
IUUC-Dno-029945	Dasypus novemcinctus	65.44	1.00e-75	276.00
IUUC-Dor-030141	Dipodomys ordii	60.22	2.00e-73	268.00
IUUC-Ete-032709	Echinops telfairi	63.74	3.00e-84	305.00
IUUC-Eca-033432	Equus caballus	65.93	1.00e-76	279.00
IUUC-Eeu-035285	Erinaceus europaeus	67.45	2.00e-61	228.00
IUUC-Fca-036467	Felis catus	64.71	1.00e-76	279.00
IUUC-Fal-036838	Ficedula albicollis	56.23	2.00e-74	272.00
IUUC-Gmo-038748	Gadus morhua	78.17	1.00e-111	395.00
IUUC-Gac-041403	Gasterosteus aculeatus	89.68	4.00e-133	467.00
IUUC-Ggo-045481	Gorilla gorilla	53.45	2.00e-57	216.00
IUUC-Hsa-045837	Homo sapiens	66.30	3.00e-70	258.00
IUUC-Itr-049062	Ictidomys tridecemlineatus	66.18	1.00e-76	279.00
IUUC-Lch-049965	Latimeria chalumnae	66.90	4.00e-85	307.00
IUUC-Mcc-055031	Macaca mulatta	53.68	2.00e-57	216.00
IUUC-Meu-056470	Macropus eugenii	68.82	2.00e-83	302.00
IUUC-Mga-059570	Meleagris gallopavo	66.95	8.00e-68	249.00
IUUC-Mmr-061385	Microcebus murinus	65.93	8.00e-70	256.00
IUUC-Mdo-062144	Monodelphis domestica	68.82	2.00e-83	302.00
IUUC-Mmu-063215	Mus musculus	63.74	1.00e-76	279.00
IUUC-Mpu-065749	Mustela putorius furo	64.92	5.00e-68	250.00
IUUC-Nle-069122	Nomascus leucogenys	56.62	4.00e-76	278.00
IUUC-Opr-070835	Ochotona princeps	51.53	6.00e-54	203.00
IUUC-Oan-073023	Ornithorhynchus anatinus	56.25	1.00e-74	273.00
IUUC-Ocu-074870	Oryctolagus cuniculus	64.71	1.00e-76	280.00
IUUC-Ola-087400	Oryzias latipes	81.12	1.00e-87	315.00
IUUC-Olu-087851	Ostreococcus lucimarinus	67.31	1.00e-18	86.70
IUUC-Oga-088336	Otolemur garnettii	65.93	8.00e-70	256.00
IUUC-Oar-090136	Ovis aries	63.74	4.00e-76	277.00
IUUC-Ptr-090589	Pan troglodytes	56.25	1.00e-75	276.00
IUUC-Pan-092819	Papio anubis	66.30	3.00e-70	258.00
IUUC-Pfo-096633	Poecilia formosa	93.73	3.00e-127	447.00
IUUC-Pab-098346	Pongo abelii	66.54	7.00e-70	257.00
IUUC-Pca-100278	Procavia capensis	66.54	7.00e-82	296.00
IUUC-Pva-103190	Pteropus vampyrus	64.71	7.00e-77	280.00
IUUC-Rno-104940	Rattus norvegicus	64.10	2.00e-76	278.00
IUUC-Sha-107533	Sarcophilus harrisii	68.82	2.00e-83	301.00
IUUC-Sar-113630	Sorex araneus	66.67	9.00e-61	226.00
IUUC-Ssc-115734	Sus scrofa	64.71	7.00e-77	280.00
IUUC-Tru-118168	Takifugu rubripes	86.48	1.00e-113	402.00
IUUC-Tsy-119494	Tarsius syrichta	66.83	3.00e-56	211.00
IUUC-Tni-119663	Tetraodon nigroviridis	86.12	2.00e-115	407.00
IUUC-Ttr-128442	Tursiops truncatus	66.98	3.00e-61	228.00
IUUC-Vpa-130063	Vicugna pacos	64.47	4.00e-77	281.00
IUUC-Xtr-132348	Xenopus tropicalis	86.25	2.00e-33	136.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence