iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020048

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03014784

Gene Name

ZNRF3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000011973.4	ENSCAFT00000019014.4	ENSCAFP00000017623.4

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	89.32	0.00e+00	1338.00	IUUC-Hsa-046484

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Canis familiaris

Protein Sequence
(Fasta)

MHPLGLCNNN DEEDLYEYGW VGVVKLEQPE LDPKPCLTVL GKAKRAVQRG ATAVIFDVSE 60
NPEAIDQLNQ GSEDPLKRPV VYVKGADAIK LMNIVNKQKV ARARIQHRPP RQPTEYFDMG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCACCCAC TGGGCCTGTG TAATAACAAT GATGAAGAGG ACTTGTATGA ATATGGCTGG 60
GTAGGAGTGG TGAAGCTGGA ACAGCCAGAA TTGGACCCAA AACCATGCCT CACTGTCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:0072089--P:stem cell proliferation
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0038018--P:Wnt receptor catabolic process
GO:0060071--P:Wnt signaling pathway, planar cell polarity pathway

KEGG

cfa:486339

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001916	Ailuropoda melanoleuca	90.06	0.00e+00	1289.00
IUUC-Apl-004188	Anas platyrhynchos	71.38	0.00e+00	1019.00
IUUC-Aly-005850	Arabidopsis lyrata	42.68	3.00e-15	74.30
IUUC-Ath-007372	Arabidopsis thaliana	42.17	6.00e-15	73.20
IUUC-Ame-011764	Astyanax mexicanus	63.59	0.00e+00	736.00
IUUC-Bta-012478	Bos taurus	64.12	0.00e+00	663.00
IUUC-Cja-019504	Callithrix jacchus	88.04	0.00e+00	1319.00
IUUC-Cpo-021725	Cavia porcellus	81.07	0.00e+00	1202.00
IUUC-Csa-023586	Chlorocebus sabaeus	88.49	0.00e+00	1272.00
IUUC-Cho-024867	Choloepus hoffmanni	91.94	0.00e+00	686.00
IUUC-Cin-025569	Ciona intestinalis	47.11	2.00e-55	210.00
IUUC-Csv-025869	Ciona savignyi	45.04	5.00e-49	189.00
IUUC-Dre-027553	Danio rerio	65.45	0.00e+00	808.00
IUUC-Dno-029370	Dasypus novemcinctus	84.15	0.00e+00	1204.00
IUUC-Dor-030816	Dipodomys ordii	79.21	0.00e+00	1086.00
IUUC-Ete-033060	Echinops telfairi	75.59	0.00e+00	838.00
IUUC-Eca-034044	Equus caballus	90.29	0.00e+00	1338.00
IUUC-Eeu-034591	Erinaceus europaeus	68.50	9.00e-142	497.00
IUUC-Fca-036000	Felis catus	93.10	0.00e+00	1420.00
IUUC-Fal-037147	Ficedula albicollis	70.64	0.00e+00	1033.00
IUUC-Gmo-039099	Gadus morhua	51.85	2.00e-120	426.00
IUUC-Gga-041243	Gallus gallus	67.17	0.00e+00	802.00
IUUC-Gac-041340	Gasterosteus aculeatus	50.87	2.00e-114	405.00
IUUC-Gma-044387	Glycine max	50.00	6.00e-15	73.90
IUUC-Ggo-044953	Gorilla gorilla	88.50	0.00e+00	1306.00
IUUC-Hsa-046484	Homo sapiens	89.32	0.00e+00	1322.00
IUUC-Itr-048470	Ictidomys tridecemlineatus	87.17	0.00e+00	1282.00
IUUC-Lch-050004	Latimeria chalumnae	58.90	0.00e+00	659.00
IUUC-Loc-051830	Lepisosteus oculatus	66.71	0.00e+00	773.00
IUUC-Laf-053975	Loxodonta africana	85.23	0.00e+00	1256.00
IUUC-Mcc-055302	Macaca mulatta	88.26	0.00e+00	1254.00
IUUC-Meu-056263	Macropus eugenii	77.12	0.00e+00	795.00
IUUC-Mtr-058744	Medicago truncatula	54.17	2.00e-13	68.20
IUUC-Mga-059706	Meleagris gallopavo	71.22	0.00e+00	1038.00
IUUC-Mmr-061372	Microcebus murinus	87.20	0.00e+00	1195.00
IUUC-Mdo-062651	Monodelphis domestica	65.78	0.00e+00	874.00
IUUC-Mmu-064339	Mus musculus	81.88	0.00e+00	1201.00
IUUC-Mac-065356	Musa acuminata	50.00	1.00e-12	67.80
IUUC-Mpu-066211	Mustela putorius furo	88.82	0.00e+00	1316.00
IUUC-Mlu-067058	Myotis lucifugus	89.32	0.00e+00	1284.00
IUUC-Nle-069886	Nomascus leucogenys	88.97	0.00e+00	1286.00
IUUC-Opr-070218	Ochotona princeps	81.19	0.00e+00	1070.00
IUUC-Ont-072483	Oreochromis niloticus	61.00	0.00e+00	759.00
IUUC-Oan-073718	Ornithorhynchus anatinus	72.89	0.00e+00	920.00
IUUC-Ocu-073847	Oryctolagus cuniculus	80.99	0.00e+00	1044.00
IUUC-Ome-081564	Oryza meridionalis	51.85	5.00e-12	65.10
IUUC-Opu-083306	Oryza punctata	67.44	9.00e-13	66.60
IUUC-Ola-087358	Oryzias latipes	63.24	0.00e+00	779.00
IUUC-Oga-088362	Otolemur garnettii	86.67	0.00e+00	1297.00
IUUC-Oar-090197	Ovis aries	99.49	2.00e-96	346.00
IUUC-Ptr-091350	Pan troglodytes	88.96	0.00e+00	1320.00
IUUC-Pan-091700	Papio anubis	88.37	0.00e+00	1250.00
IUUC-Psi-093301	Pelodiscus sinensis	69.39	0.00e+00	979.00
IUUC-Pfo-096917	Poecilia formosa	62.75	0.00e+00	751.00
IUUC-Pab-097932	Pongo abelii	88.28	0.00e+00	1323.00
IUUC-Pop-099640	Populus trichocarpa	57.14	2.00e-14	72.40
IUUC-Pca-101054	Procavia capensis	93.21	0.00e+00	959.00
IUUC-Pva-102879	Pteropus vampyrus	90.20	0.00e+00	1350.00
IUUC-Pgr-103476	Puccinia graminis	41.27	3.00e-09	55.80
IUUC-Sha-106507	Sarcophilus harrisii	53.39	1.00e-162	566.00
IUUC-Sit-110656	Setaria italica	67.44	8.00e-13	66.60
IUUC-Stu-112500	Solanum tuberosum	62.79	6.00e-13	67.00
IUUC-Sar-113182	Sorex araneus	82.69	3.00e-112	399.00
IUUC-Sbi-114414	Sorghum bicolor	41.03	6.00e-13	66.60
IUUC-Ssc-115966	Sus scrofa	84.70	0.00e+00	1097.00
IUUC-Tgu-116864	Taeniopygia guttata	62.70	0.00e+00	667.00
IUUC-Tru-118502	Takifugu rubripes	60.98	0.00e+00	728.00
IUUC-Tsy-119210	Tarsius syrichta	86.48	0.00e+00	1243.00
IUUC-Tni-120344	Tetraodon nigroviridis	52.47	2.00e-120	426.00
IUUC-Tca-120966	Theobroma cacao	48.44	2.00e-13	70.50
IUUC-Tbe-127735	Tupaia belangeri	84.71	2.00e-131	462.00
IUUC-Ttr-128714	Tursiops truncatus	75.60	0.00e+00	1007.00
IUUC-Xtr-132280	Xenopus tropicalis	61.13	0.00e+00	696.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence