iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044953

UUCD1 version

UUC-GoG-00339

Ensembl Protein ID

ENSGGOP00000008101.2

UniProt Accession

G3QZ04; G3QZ04_GORGO

Protein Name

Uncharacterized protein

Gene Name

ZNRF3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000008289.2	ENSGGOT00000008326.2	ENSGGOP00000008101.2
ENSGGOG00000008289.2	ENSGGOT00000028011.1	ENSGGOP00000027052.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	98.93	0.00e+00	1475.00	IUUC-Hsa-046484

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MHPLGLCNNN DEEDLYEYGW VGVVKLEQPE LDPKPCLTVL GKAKRAVQRG ATAVIFDVSE 60
NPEAIDQLNQ GSEDPLKRPV VYVKGADAIK LMNIVNKQKV ARARIQHRPP RQPTEYFDMG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGATGCACCC ACTGGGCCTA TGTAATAACA ATGACGAAGA GGACTTGTAT GAATATGGCT 60
GGGTAGGAGT GGTGAAGCTA GAACAGCCAG AATTGGACCC GAAACCATGC CTCACTGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:0072089--P:stem cell proliferation
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0038018--P:Wnt receptor catabolic process
GO:0060071--P:Wnt signaling pathway, planar cell polarity pathway

KEGG

ggo:101153381

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001916	Ailuropoda melanoleuca	87.18	0.00e+00	1229.00
IUUC-Apl-004188	Anas platyrhynchos	71.45	0.00e+00	1042.00
IUUC-Aly-005850	Arabidopsis lyrata	42.68	5.00e-15	73.60
IUUC-Ath-007372	Arabidopsis thaliana	42.68	2.00e-14	71.60
IUUC-Ame-011764	Astyanax mexicanus	61.83	0.00e+00	723.00
IUUC-Bta-012478	Bos taurus	67.20	0.00e+00	657.00
IUUC-Bol-016217	Brassica oleracea	56.25	3.00e-14	70.50
IUUC-Bra-017407	Brassica rapa	56.25	3.00e-14	70.90
IUUC-Cja-019504	Callithrix jacchus	94.03	0.00e+00	1446.00
IUUC-Cfa-020048	Canis familiaris	87.54	0.00e+00	1321.00
IUUC-Cpo-021725	Cavia porcellus	81.48	0.00e+00	1197.00
IUUC-Csa-023586	Chlorocebus sabaeus	95.03	0.00e+00	1417.00
IUUC-Cho-024867	Choloepus hoffmanni	92.19	0.00e+00	689.00
IUUC-Cin-025569	Ciona intestinalis	47.11	1.00e-55	211.00
IUUC-Csv-025869	Ciona savignyi	45.04	5.00e-49	189.00
IUUC-Dre-027553	Danio rerio	63.83	0.00e+00	792.00
IUUC-Dno-029370	Dasypus novemcinctus	85.51	0.00e+00	1220.00
IUUC-Dor-030816	Dipodomys ordii	80.07	0.00e+00	1126.00
IUUC-Ete-033060	Echinops telfairi	75.78	0.00e+00	846.00
IUUC-Eca-034044	Equus caballus	89.94	0.00e+00	1318.00
IUUC-Eeu-034591	Erinaceus europaeus	67.14	2.00e-137	483.00
IUUC-Fca-036000	Felis catus	89.05	0.00e+00	1324.00
IUUC-Fal-037147	Ficedula albicollis	71.01	0.00e+00	1056.00
IUUC-Gmo-039099	Gadus morhua	50.09	5.00e-118	418.00
IUUC-Ggr-039947	Gaeumannomyces graminis	30.43	4.00e-11	63.20
IUUC-Gga-041243	Gallus gallus	67.67	0.00e+00	829.00
IUUC-Gac-041340	Gasterosteus aculeatus	49.65	5.00e-114	404.00
IUUC-Gma-044387	Glycine max	50.00	5.00e-15	74.30
IUUC-Hsa-046484	Homo sapiens	97.97	0.00e+00	1476.00
IUUC-Itr-048470	Ictidomys tridecemlineatus	87.32	0.00e+00	1294.00
IUUC-Lch-050004	Latimeria chalumnae	58.55	0.00e+00	671.00
IUUC-Loc-051830	Lepisosteus oculatus	62.81	0.00e+00	776.00
IUUC-Laf-053975	Loxodonta africana	85.97	0.00e+00	1259.00
IUUC-Mcc-055302	Macaca mulatta	94.56	0.00e+00	1379.00
IUUC-Meu-056263	Macropus eugenii	75.27	0.00e+00	793.00
IUUC-Mtr-058744	Medicago truncatula	54.17	2.00e-13	68.60
IUUC-Mga-059706	Meleagris gallopavo	71.19	0.00e+00	1058.00
IUUC-Mmr-061372	Microcebus murinus	88.31	0.00e+00	1239.00
IUUC-Mdo-062651	Monodelphis domestica	65.43	0.00e+00	866.00
IUUC-Mmu-064339	Mus musculus	84.21	0.00e+00	1246.00
IUUC-Mac-065356	Musa acuminata	50.00	1.00e-12	67.80
IUUC-Mpu-066211	Mustela putorius furo	86.79	0.00e+00	1268.00
IUUC-Mlu-067058	Myotis lucifugus	88.10	0.00e+00	1241.00
IUUC-Nle-069886	Nomascus leucogenys	96.86	0.00e+00	1434.00
IUUC-Opr-070218	Ochotona princeps	82.46	0.00e+00	1102.00
IUUC-Ont-072483	Oreochromis niloticus	61.25	0.00e+00	770.00
IUUC-Oan-073718	Ornithorhynchus anatinus	71.16	0.00e+00	917.00
IUUC-Ocu-073847	Oryctolagus cuniculus	80.90	0.00e+00	1069.00
IUUC-Oba-075528	Oryza barthii	43.64	3.00e-12	65.90
IUUC-Obr-076184	Oryza brachyantha	53.33	2.00e-12	66.60
IUUC-Opu-083306	Oryza punctata	67.44	7.00e-13	67.00
IUUC-Ola-087358	Oryzias latipes	61.74	0.00e+00	764.00
IUUC-Oga-088362	Otolemur garnettii	86.40	0.00e+00	1324.00
IUUC-Oar-090197	Ovis aries	99.49	1.00e-96	347.00
IUUC-Ptr-091350	Pan troglodytes	97.73	0.00e+00	1474.00
IUUC-Pan-091700	Papio anubis	94.56	0.00e+00	1373.00
IUUC-Psi-093301	Pelodiscus sinensis	69.57	0.00e+00	986.00
IUUC-Pfo-096917	Poecilia formosa	62.84	0.00e+00	763.00
IUUC-Pab-097932	Pongo abelii	96.30	0.00e+00	1472.00
IUUC-Pop-099640	Populus trichocarpa	57.14	1.00e-14	72.80
IUUC-Pca-101054	Procavia capensis	94.07	0.00e+00	966.00
IUUC-Pva-102879	Pteropus vampyrus	89.86	0.00e+00	1343.00
IUUC-Pgr-103476	Puccinia graminis	41.27	3.00e-09	55.80
IUUC-Sha-106507	Sarcophilus harrisii	54.29	9.00e-165	573.00
IUUC-Sit-110656	Setaria italica	67.44	6.00e-13	67.00
IUUC-Stu-112500	Solanum tuberosum	62.79	8.00e-13	66.60
IUUC-Sar-113182	Sorex araneus	81.98	2.00e-111	396.00
IUUC-Sbi-114414	Sorghum bicolor	41.03	7.00e-13	66.20
IUUC-Ssc-115966	Sus scrofa	82.57	0.00e+00	1075.00
IUUC-Tgu-116864	Taeniopygia guttata	63.29	0.00e+00	679.00
IUUC-Tru-118502	Takifugu rubripes	60.82	0.00e+00	738.00
IUUC-Tsy-119210	Tarsius syrichta	88.19	0.00e+00	1285.00
IUUC-Tni-120344	Tetraodon nigroviridis	52.22	6.00e-123	434.00
IUUC-Tca-120966	Theobroma cacao	48.39	3.00e-13	69.30
IUUC-Tur-125977	Triticum urartu	50.00	2.00e-13	70.10
IUUC-Tbe-127735	Tupaia belangeri	83.89	8.00e-134	471.00
IUUC-Ttr-128714	Tursiops truncatus	75.47	0.00e+00	1001.00
IUUC-Vvi-131280	Vitis vinifera	31.50	3.00e-13	69.30
IUUC-Xtr-132280	Xenopus tropicalis	58.11	0.00e+00	695.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence