iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-055302

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

JSUE03005243

Gene Name

ZNRF3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000000025.3	ENSMMUT00000000033.3	ENSMMUP00000000030.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	96.09	0.00e+00	1393.00	IUUC-Hsa-046484

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MMHPLGLCNN NDEEDLYEYG WVGVVKLEQP ELDPKPCLTV LGKAKRAVQR GATAVIFDVS 60
ENPEAIDQLN QGSEDPLKRP VVYVKGADAI KLMNIVNKQK VARARIQHRP PRQPTEYFDM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGAGTG GTACTGCTTT TCTTATTTGG GATACTCATT AGAGTTGCTC TGTGGAGATG 60
GAATGATGGT GGGGTGCAGT TAAACACAGC TGAGTGCTTT CTGCTTAAGG ACCTGATGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:0072089--P:stem cell proliferation
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0038018--P:Wnt receptor catabolic process
GO:0060071--P:Wnt signaling pathway, planar cell polarity pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001916	Ailuropoda melanoleuca	85.46	0.00e+00	1221.00
IUUC-Apl-004188	Anas platyrhynchos	71.26	0.00e+00	1036.00
IUUC-Aly-005850	Arabidopsis lyrata	42.68	4.00e-15	73.90
IUUC-Ath-007372	Arabidopsis thaliana	42.68	2.00e-14	71.60
IUUC-Ame-011764	Astyanax mexicanus	62.09	0.00e+00	730.00
IUUC-Bta-012478	Bos taurus	65.53	0.00e+00	659.00
IUUC-Bol-016217	Brassica oleracea	56.25	3.00e-14	70.50
IUUC-Bra-017407	Brassica rapa	56.25	3.00e-14	70.90
IUUC-Cja-019504	Callithrix jacchus	95.26	0.00e+00	1456.00
IUUC-Cfa-020048	Canis familiaris	88.73	0.00e+00	1325.00
IUUC-Cpo-021725	Cavia porcellus	81.11	0.00e+00	1191.00
IUUC-Csa-023586	Chlorocebus sabaeus	99.17	0.00e+00	1459.00
IUUC-Cho-024867	Choloepus hoffmanni	90.84	0.00e+00	679.00
IUUC-Cin-025569	Ciona intestinalis	47.11	1.00e-55	211.00
IUUC-Csv-025869	Ciona savignyi	45.04	5.00e-49	189.00
IUUC-Dre-027553	Danio rerio	64.64	0.00e+00	796.00
IUUC-Dno-029370	Dasypus novemcinctus	84.07	0.00e+00	1205.00
IUUC-Dor-030816	Dipodomys ordii	81.02	0.00e+00	1127.00
IUUC-Ete-033060	Echinops telfairi	74.30	0.00e+00	834.00
IUUC-Eca-034044	Equus caballus	87.48	0.00e+00	1304.00
IUUC-Eeu-034591	Erinaceus europaeus	66.53	3.00e-136	479.00
IUUC-Fca-036000	Felis catus	87.91	0.00e+00	1327.00
IUUC-Fal-037147	Ficedula albicollis	70.28	0.00e+00	1040.00
IUUC-Gmo-039099	Gadus morhua	58.87	2.00e-109	389.00
IUUC-Gga-041243	Gallus gallus	67.21	0.00e+00	825.00
IUUC-Gac-041340	Gasterosteus aculeatus	49.66	2.00e-115	409.00
IUUC-Gma-044387	Glycine max	41.98	5.00e-15	74.30
IUUC-Ggo-044953	Gorilla gorilla	95.86	0.00e+00	1437.00
IUUC-Hsa-046484	Homo sapiens	97.39	0.00e+00	1452.00
IUUC-Itr-048470	Ictidomys tridecemlineatus	88.33	0.00e+00	1297.00
IUUC-Lch-050004	Latimeria chalumnae	58.42	0.00e+00	669.00
IUUC-Loc-051830	Lepisosteus oculatus	63.65	0.00e+00	776.00
IUUC-Laf-053975	Loxodonta africana	85.11	0.00e+00	1249.00
IUUC-Meu-056263	Macropus eugenii	73.81	0.00e+00	780.00
IUUC-Mtr-058744	Medicago truncatula	54.17	2.00e-13	68.60
IUUC-Mga-059706	Meleagris gallopavo	71.34	0.00e+00	1056.00
IUUC-Mmr-061372	Microcebus murinus	89.92	0.00e+00	1241.00
IUUC-Mdo-062651	Monodelphis domestica	65.20	0.00e+00	862.00
IUUC-Mmu-064339	Mus musculus	83.58	0.00e+00	1241.00
IUUC-Mac-065356	Musa acuminata	50.00	1.00e-12	67.80
IUUC-Mpu-066211	Mustela putorius furo	85.98	0.00e+00	1263.00
IUUC-Mlu-067058	Myotis lucifugus	87.67	0.00e+00	1237.00
IUUC-Nle-069886	Nomascus leucogenys	97.24	0.00e+00	1423.00
IUUC-Opr-070218	Ochotona princeps	83.74	0.00e+00	1109.00
IUUC-Ont-072483	Oreochromis niloticus	61.16	0.00e+00	770.00
IUUC-Oan-073718	Ornithorhynchus anatinus	70.76	0.00e+00	915.00
IUUC-Ocu-073847	Oryctolagus cuniculus	80.80	0.00e+00	1056.00
IUUC-Opu-083306	Oryza punctata	67.44	7.00e-13	67.00
IUUC-Ola-087358	Oryzias latipes	62.42	0.00e+00	771.00
IUUC-Oga-088362	Otolemur garnettii	88.46	0.00e+00	1325.00
IUUC-Oar-090197	Ovis aries	99.49	9.00e-97	347.00
IUUC-Ptr-091350	Pan troglodytes	97.27	0.00e+00	1450.00
IUUC-Pan-091700	Papio anubis	99.29	0.00e+00	1408.00
IUUC-Psi-093301	Pelodiscus sinensis	68.80	0.00e+00	977.00
IUUC-Pfo-096917	Poecilia formosa	63.58	0.00e+00	762.00
IUUC-Pab-097932	Pongo abelii	96.68	0.00e+00	1462.00
IUUC-Pop-099640	Populus trichocarpa	57.14	1.00e-14	72.80
IUUC-Pca-101054	Procavia capensis	92.11	0.00e+00	954.00
IUUC-Pva-102879	Pteropus vampyrus	88.74	0.00e+00	1332.00
IUUC-Pgr-103476	Puccinia graminis	41.27	3.00e-09	55.80
IUUC-Sha-106507	Sarcophilus harrisii	54.95	9.00e-164	570.00
IUUC-Sit-110656	Setaria italica	67.44	6.00e-13	67.00
IUUC-Stu-112500	Solanum tuberosum	62.79	9.00e-13	66.20
IUUC-Sar-113182	Sorex araneus	81.98	1.00e-111	397.00
IUUC-Sbi-114414	Sorghum bicolor	41.03	7.00e-13	66.20
IUUC-Ssc-115966	Sus scrofa	80.72	0.00e+00	1062.00
IUUC-Tgu-116864	Taeniopygia guttata	62.64	0.00e+00	669.00
IUUC-Tru-118502	Takifugu rubripes	61.50	0.00e+00	742.00
IUUC-Tsy-119210	Tarsius syrichta	88.85	0.00e+00	1282.00
IUUC-Tni-120344	Tetraodon nigroviridis	52.72	7.00e-125	441.00
IUUC-Tca-120966	Theobroma cacao	48.39	4.00e-13	69.30
IUUC-Tbe-127735	Tupaia belangeri	85.29	2.00e-132	466.00
IUUC-Ttr-128714	Tursiops truncatus	77.39	0.00e+00	1003.00
IUUC-Vvi-131280	Vitis vinifera	31.50	4.00e-13	69.30
IUUC-Xtr-132280	Xenopus tropicalis	57.79	0.00e+00	693.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence