iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-036276

Ensembl Protein ID

ENSFCAP00000018231.1

UniProt Accession

M3WV44; M3WV44_FELCA

Genbank Protein ID

ENSFCAP00000018231

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02047011

Gene Name

LONRF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000022308.1	ENSFCAT00000026399.1	ENSFCAP00000018231.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	6.40e-08	32.6	301	347
E3 activity/RING/RING	3.50e-07	30.7	304	342

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 5    eflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplte 52
           +f C++ + l  +Pv++p+G+t+  +++e++l++  + cP+++++l+e
   Q: 301  DFECALCMRLLFEPVTTPCGHTFCLKCLERCLDHAPH-CPLCKEKLSE 347
           79***********************************.********86 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C+  +++ p+++pCgH+f+++Cl++          + +CPlC+
   Q: 304  CALCMRLLFE-PVTTPCGHTFCLKCLERC------LDHAPHCPLCK 342
           **********.9**************999......9*********7 PP

Organism

Felis catus

Protein Sequence
(Fasta)

PVTLPCGLTV CKRCVESGPV RPQARRVNVV LSGLLEKCFP TECRVRRLAG QARSLQRQQQ 60
PEAALLRCDQ ALDLVPRDNS LLLLRAELYL TMKNYEQALQ DANAVCQNEP LLTKGHHVKA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGGTGACCC TGCCGTGCGG GCTGACGGTG TGCAAGCGCT GCGTGGAGTC CGGCCCTGTC 60
CGGCCGCAGG CGCGGCGAGT CAACGTGGTA CTGAGCGGCC TGCTGGAGAA GTGCTTTCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003111--Lon_substr-bd
IPR015947--PUA-like_domain
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51787--LON_N
PS50293--TPR_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02190--LON_substr_bdg

SMART

SM00464--LON
SM00184--RING
SM00028--TPR

Gene Ontology

GO:0005622--C:intracellular
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001867	Ailuropoda melanoleuca	95.39	0.00e+00	1141.00
IUUC-Apl-003355	Anas platyrhynchos	63.94	0.00e+00	696.00
IUUC-Aca-004822	Anolis carolinensis	59.52	0.00e+00	737.00
IUUC-Acl-008224	Aspergillus clavatus	33.03	4.00e-40	159.00
IUUC-Afu-008802	Aspergillus fumigatus	30.37	1.00e-38	154.00
IUUC-Ani-009473	Aspergillus nidulans	31.29	3.00e-41	163.00
IUUC-Ame-010750	Astyanax mexicanus	51.70	5.00e-167	581.00
IUUC-Cja-019041	Callithrix jacchus	84.56	0.00e+00	998.00
IUUC-Cfa-020025	Canis familiaris	94.82	0.00e+00	1111.00
IUUC-Cre-022730	Chlamydomonas reinhardtii	45.45	4.00e-08	51.60
IUUC-Csa-023324	Chlorocebus sabaeus	86.68	0.00e+00	888.00
IUUC-Cin-025668	Ciona intestinalis	32.45	6.00e-86	311.00
IUUC-Dre-028400	Danio rerio	51.79	8.00e-147	513.00
IUUC-Eeu-034779	Erinaceus europaeus	70.13	0.00e+00	686.00
IUUC-Fal-036669	Ficedula albicollis	62.27	0.00e+00	706.00
IUUC-Gga-041253	Gallus gallus	59.81	0.00e+00	737.00
IUUC-Ggo-045501	Gorilla gorilla	87.36	0.00e+00	1032.00
IUUC-Hsa-046630	Homo sapiens	87.36	0.00e+00	1030.00
IUUC-Itr-048224	Ictidomys tridecemlineatus	83.20	0.00e+00	849.00
IUUC-Lch-049788	Latimeria chalumnae	52.66	0.00e+00	631.00
IUUC-Loc-051922	Lepisosteus oculatus	51.44	6.00e-171	594.00
IUUC-Laf-054421	Loxodonta africana	63.39	0.00e+00	710.00
IUUC-Mcc-054828	Macaca mulatta	86.10	0.00e+00	885.00
IUUC-Meu-055901	Macropus eugenii	54.55	0.00e+00	631.00
IUUC-Mga-059760	Meleagris gallopavo	63.21	0.00e+00	705.00
IUUC-Mmr-061350	Microcebus murinus	80.49	0.00e+00	897.00
IUUC-Mdo-062203	Monodelphis domestica	63.33	0.00e+00	782.00
IUUC-Mmu-064118	Mus musculus	79.01	0.00e+00	804.00
IUUC-Mpu-065764	Mustela putorius furo	94.42	0.00e+00	1139.00
IUUC-Nle-069616	Nomascus leucogenys	87.52	0.00e+00	1033.00
IUUC-Ont-072142	Oreochromis niloticus	48.97	4.00e-165	575.00
IUUC-Oga-088972	Otolemur garnettii	86.89	0.00e+00	1028.00
IUUC-Ptr-090992	Pan troglodytes	87.33	0.00e+00	984.00
IUUC-Pan-092180	Papio anubis	86.04	0.00e+00	1016.00
IUUC-Psi-093423	Pelodiscus sinensis	63.60	0.00e+00	692.00
IUUC-Pfo-096363	Poecilia formosa	51.20	1.00e-161	563.00
IUUC-Pab-097974	Pongo abelii	87.36	0.00e+00	1030.00
IUUC-Pva-102269	Pteropus vampyrus	84.29	0.00e+00	976.00
IUUC-Pgr-103289	Puccinia graminis	26.69	5.00e-29	122.00
IUUC-Ptt-103898	Puccinia triticina	26.87	2.00e-28	120.00
IUUC-Rno-105905	Rattus norvegicus	80.78	0.00e+00	838.00
IUUC-Ssc-116224	Sus scrofa	76.92	5.00e-163	567.00
IUUC-Tgu-117000	Taeniopygia guttata	62.46	0.00e+00	729.00
IUUC-Tru-118016	Takifugu rubripes	49.67	6.00e-154	537.00
IUUC-Tni-119913	Tetraodon nigroviridis	48.60	2.00e-155	542.00
IUUC-Ttr-128666	Tursiops truncatus	84.26	0.00e+00	995.00
IUUC-Vpa-130334	Vicugna pacos	70.22	0.00e+00	669.00
IUUC-Xtr-132065	Xenopus tropicalis	53.87	0.00e+00	630.00
IUUC-Xma-134324	Xiphophorus maculatus	51.11	2.00e-162	565.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence