iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133995

Ensembl Protein ID

ENSXMAP00000008846.1

UniProt Accession

M4A302; M4A302_XIPMA

Genbank Protein ID

ENSXMAP00000008846

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01027571

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000008818.1	ENSXMAT00000008860.1	ENSXMAP00000008846.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-58	198.9	148	633

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeef 84
           +G++N+gNtC++ +v+Q+L+++p +r+l+l+     +  ek++  + ++++ +++++l+ lf+ ++ s+++ v+p++ ++ l+++ +  
   Q: 148  VGIRNIGNTCWFSAVIQSLFHLPVFRRLVLNyhlseRILEKCKSHA-DKRNIAFMQELRCLFALMVGSTRRFVDPSAAVELLRDAFRT- 234
           6******************************999887888888765.7999********************************99987. PP
   S: 85   sgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
            + +qqD++Ef + lld le++++                     + ++ + k+++++++lF g++ ++    + +++    e+f +++
   Q: 235  -SEAQQDVSEFSHKLLDWLEDAFQL------------------AANGKNAEDKQQNPMVRLFYGTFVTE--RRHEGKTLYNIEQFGQYP 302
           .89********************22..................3356789999*************965..5567888899******** PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls 262
           l+v+g +     +l++cLe  + e+e+e+   +++   ++ +++ ++ ++kklP+vL+++L+Rf+f+ + +++eki+kk+efp+ + ++
   Q: 303  LQVNGFS-----NLDECLEGAMVEKEIES---LHS---DHAVTSGRERWFKKLPPVLTFELSRFEFNTQLGRPEKIHKKLEFPQIVYMD 380
           *******.....9***********99995...555...556778899****************************************** PP
   S: 263  pfcts...................................................................peekqke.......... 274
           +++++                                                                         +          
   Q: 381  RYLHKniertnerrgevkklkeqlaalqqklecyknygsgpmkypladmlqfvlefattkptsvspaedsrlA-----Tsspppvshpl 464
           *****66666666666666666666666666666666666666655555555555555555555555555550.....05555555555 PP
   S: 275  ......................................................................................... 274
                                                                                                    
   Q: 465  pdaiakdssepgdkdssdglvssvsncqqtpiykpftqckhpsdrpphpaphsateeelhfvktclrrwrtevehdinelktsidkltq 553
           55555555555556666666666666666667777777777777777777777777778888888888888888888888888888889 PP
   S: 275  ............kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                       ++ Y+L+av+vH+G++s GHY+ay++++ ++ W++++D ++te+++ee ++++      ++aY+l+Y 
   Q: 554  tlegmysdnslcQVPYRLHAVLVHEGQASAGHYWAYIYDHANQrWMKYNDVSITESSWEELERDSFggmtnASAYCLMYI 633
           999999999999***************************88888*******************87799***********6 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MRAEQSENGE NSTNSLKMLM EQLKEITGIQ DQQVLYKALK ASQGDVGHAV GLLTTQTVEV 60
QDSAEPQESG ASAETWDKQR GLPKDELQTA IELSLQESHN AEQEEREFNR ALEASAEENA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCACCGCAGC TGGCTGCTCG CTCTCGGCGC GTGGCAGATG GAGTCGATTT GAACGAGACA 60
GAGAGAGAGA GCGTCTGCCG CGAGCCCTTT TTGGAGGGGA AAAGACGTGA ATAAATCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0021551--P:central nervous system morphogenesis
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001836	Ailuropoda melanoleuca	56.45	0.00e+00	761.00
IUUC-Aca-004741	Anolis carolinensis	51.99	0.00e+00	694.00
IUUC-Ang-009577	Aspergillus niger	33.33	3.00e-11	64.70
IUUC-Ate-010275	Aspergillus terreus	35.05	7.00e-11	63.20
IUUC-Ame-011910	Astyanax mexicanus	64.56	1.00e-175	611.00
IUUC-Bgr-011993	Blumeria graminis	39.19	2.00e-13	72.00
IUUC-Bta-013377	Bos taurus	55.38	0.00e+00	739.00
IUUC-Cel-018346	Caenorhabditis elegans	26.95	1.00e-27	119.00
IUUC-Cja-019977	Callithrix jacchus	56.89	0.00e+00	746.00
IUUC-Cfa-020378	Canis familiaris	58.12	0.00e+00	762.00
IUUC-Cpo-021817	Cavia porcellus	55.75	0.00e+00	734.00
IUUC-Csa-023446	Chlorocebus sabaeus	56.53	0.00e+00	743.00
IUUC-Cho-024717	Choloepus hoffmanni	52.28	4.00e-98	353.00
IUUC-Cme-027167	Cyanidioschyzon merolae	32.58	7.00e-17	83.20
IUUC-Dre-028105	Danio rerio	74.46	0.00e+00	1002.00
IUUC-Dor-030955	Dipodomys ordii	54.96	0.00e+00	710.00
IUUC-Ete-032828	Echinops telfairi	56.01	8.00e-136	478.00
IUUC-Eca-034300	Equus caballus	56.89	0.00e+00	717.00
IUUC-Eeu-034458	Erinaceus europaeus	55.64	0.00e+00	711.00
IUUC-Fca-035753	Felis catus	58.01	0.00e+00	770.00
IUUC-Gmo-039593	Gadus morhua	73.96	0.00e+00	1018.00
IUUC-Gac-041867	Gasterosteus aculeatus	84.08	0.00e+00	1217.00
IUUC-Ggo-045384	Gorilla gorilla	56.61	0.00e+00	742.00
IUUC-Hsa-046277	Homo sapiens	56.85	0.00e+00	747.00
IUUC-Kpa-049349	Komagataella pastoris	34.04	5.00e-10	60.50
IUUC-Loc-052636	Lepisosteus oculatus	68.83	0.00e+00	968.00
IUUC-Laf-053808	Loxodonta africana	54.46	0.00e+00	744.00
IUUC-Mcc-055473	Macaca mulatta	56.53	0.00e+00	744.00
IUUC-Mmr-060720	Microcebus murinus	55.80	0.00e+00	705.00
IUUC-Mdo-061955	Monodelphis domestica	50.53	0.00e+00	780.00
IUUC-Mpu-066454	Mustela putorius furo	57.14	0.00e+00	753.00
IUUC-Nle-070044	Nomascus leucogenys	56.61	0.00e+00	741.00
IUUC-Opr-070888	Ochotona princeps	64.18	1.00e-96	348.00
IUUC-Ont-072386	Oreochromis niloticus	82.66	0.00e+00	1964.00
IUUC-Ocu-074523	Oryctolagus cuniculus	55.03	0.00e+00	723.00
IUUC-Ola-086393	Oryzias latipes	83.64	0.00e+00	1177.00
IUUC-Oga-088618	Otolemur garnettii	57.80	0.00e+00	749.00
IUUC-Oar-089848	Ovis aries	53.88	0.00e+00	732.00
IUUC-Psi-093422	Pelodiscus sinensis	55.19	0.00e+00	738.00
IUUC-Pma-094250	Petromyzon marinus	45.64	2.00e-69	255.00
IUUC-Pno-095093	Phaeosphaeria nodorum	32.71	6.00e-13	70.10
IUUC-Pfo-096466	Poecilia formosa	96.74	0.00e+00	2289.00
IUUC-Pab-098337	Pongo abelii	56.55	0.00e+00	739.00
IUUC-Pva-102226	Pteropus vampyrus	53.10	9.00e-180	624.00
IUUC-Rno-105735	Rattus norvegicus	56.83	0.00e+00	756.00
IUUC-Ssl-108532	Sclerotinia sclerotiorum	34.57	8.00e-10	59.70
IUUC-Tru-117807	Takifugu rubripes	80.82	0.00e+00	1139.00
IUUC-Tni-119983	Tetraodon nigroviridis	75.91	0.00e+00	1130.00
IUUC-Ttr-128887	Tursiops truncatus	50.96	0.00e+00	645.00
IUUC-Uma-129338	Ustilago maydis	24.68	1.00e-14	76.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence