iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-055109

UUCD1 version

UUC-MaM-00809

Ensembl Protein ID

ENSMMUP00000029120.2

UniProt Accession

F7H5S3; G7MJ68; F7H5S3_MACMU

Genbank Protein ID

EHH16560.1

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

JSUE03024075

Gene Name

KLHL6; EGK_11853

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000022115.2	ENSMMUT00000031111.2	ENSMMUP00000029120.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.90e-19	69.9	70	133
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	7.20e-11	41.2	169	199

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +Dvil+v+ +ef++h++vLaa+S +F+a+f ++l+e+  ++++ ik+v++e + +ll++ Yt+k+
   Q: 70   TDVILCVDIQEFSCHRVVLAAASNYFRAMFCNDLKEKY-EKRIIIKGVDAETMHTLLDYTYTSKA 133
           7***********************************97.***********************987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           +eNc+gilr+Ad+++++ Lk++++++i+++F
   Q: 169  PENCVGILRLADTHSLDSLKKQVQSYIIQNF 199
           89***************************** PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MAGQRGAWTM GDVVEKSLEG PLAPSTDEPS QKRGDLVEIL NGEKVKFDDA GLSLILQNGL 60
ETLRMENALT DVILCVDIQE FSCHRVVLAA ASNYFRAMFC NDLKEKYEKR IIIKGVDAET 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGGAC AAAGGGGCGC CTGGACCATG GGTGACGTGG TTGAGAAGAG TTTGGAAGGG 60
CCTCTGGCAC CTTCTACAGA TGAGCCCTCC CAGAAAAGAG GAGACTTGGT GGAGATCCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR029851--KLHL6
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0000976--F:transcription regulatory region sequence-specific DNA binding
GO:0050853--P:B cell receptor signaling pathway
GO:0002467--P:germinal center formation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

KEGG

mcc:705455

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001509	Ailuropoda melanoleuca	98.22	0.00e+00	1273.00
IUUC-Apl-003490	Anas platyrhynchos	85.41	0.00e+00	1110.00
IUUC-Aca-005136	Anolis carolinensis	84.07	0.00e+00	1066.00
IUUC-Ame-010886	Astyanax mexicanus	66.77	0.00e+00	827.00
IUUC-Bta-013473	Bos taurus	96.93	0.00e+00	1231.00
IUUC-Cja-018888	Callithrix jacchus	98.52	0.00e+00	1258.00
IUUC-Cfa-020831	Canis familiaris	46.42	1.00e-136	479.00
IUUC-Cpo-021761	Cavia porcellus	88.67	0.00e+00	1113.00
IUUC-Csa-023206	Chlorocebus sabaeus	100.00	0.00e+00	1292.00
IUUC-Cin-025367	Ciona intestinalis	40.79	3.00e-132	465.00
IUUC-Csv-026076	Ciona savignyi	41.21	9.00e-126	443.00
IUUC-Dre-027948	Danio rerio	73.22	0.00e+00	902.00
IUUC-Dno-030045	Dasypus novemcinctus	97.09	0.00e+00	1259.00
IUUC-Dor-030839	Dipodomys ordii	89.01	0.00e+00	1123.00
IUUC-Ete-033161	Echinops telfairi	93.49	2.00e-161	562.00
IUUC-Eca-033608	Equus caballus	96.93	0.00e+00	1231.00
IUUC-Eeu-034640	Erinaceus europaeus	95.08	0.00e+00	1214.00
IUUC-Fca-036065	Felis catus	97.09	0.00e+00	1261.00
IUUC-Fal-036949	Ficedula albicollis	85.83	0.00e+00	1091.00
IUUC-Fso-038219	Fusarium solani	39.68	1.00e-09	53.90
IUUC-Gmo-039661	Gadus morhua	58.32	1.00e-175	609.00
IUUC-Gga-040740	Gallus gallus	84.26	0.00e+00	1097.00
IUUC-Gac-042413	Gasterosteus aculeatus	61.35	0.00e+00	782.00
IUUC-Ggo-045167	Gorilla gorilla	99.68	0.00e+00	1288.00
IUUC-Hsa-046120	Homo sapiens	99.84	0.00e+00	1289.00
IUUC-Itr-047926	Ictidomys tridecemlineatus	97.42	0.00e+00	1259.00
IUUC-Lch-049709	Latimeria chalumnae	79.32	0.00e+00	1037.00
IUUC-Loc-052239	Lepisosteus oculatus	77.70	0.00e+00	972.00
IUUC-Laf-054511	Loxodonta africana	96.39	0.00e+00	1234.00
IUUC-Meu-056522	Macropus eugenii	74.79	9.00e-104	370.00
IUUC-Mga-060012	Meleagris gallopavo	82.39	0.00e+00	1068.00
IUUC-Mmr-061364	Microcebus murinus	97.58	0.00e+00	1264.00
IUUC-Mdo-063033	Monodelphis domestica	83.12	0.00e+00	1018.00
IUUC-Mmu-063880	Mus musculus	94.83	0.00e+00	1196.00
IUUC-Mpu-065928	Mustela putorius furo	46.42	1.00e-136	479.00
IUUC-Mlu-068233	Myotis lucifugus	96.77	0.00e+00	1230.00
IUUC-Nle-069293	Nomascus leucogenys	46.42	9.00e-137	480.00
IUUC-Opr-070638	Ochotona princeps	95.76	0.00e+00	892.00
IUUC-Ont-071960	Oreochromis niloticus	61.37	0.00e+00	785.00
IUUC-Oan-073406	Ornithorhynchus anatinus	83.77	0.00e+00	1073.00
IUUC-Ocu-074612	Oryctolagus cuniculus	96.61	0.00e+00	1251.00
IUUC-Ola-087181	Oryzias latipes	59.19	0.00e+00	761.00
IUUC-Oga-088955	Otolemur garnettii	97.09	0.00e+00	1256.00
IUUC-Oar-089682	Ovis aries	96.93	0.00e+00	1231.00
IUUC-Ptr-090969	Pan troglodytes	99.68	0.00e+00	1286.00
IUUC-Pan-092289	Papio anubis	100.00	0.00e+00	1292.00
IUUC-Psi-093279	Pelodiscus sinensis	85.20	0.00e+00	1115.00
IUUC-Pfo-096218	Poecilia formosa	46.00	4.00e-144	504.00
IUUC-Pab-097957	Pongo abelii	100.00	0.00e+00	952.00
IUUC-Pca-100619	Procavia capensis	93.21	0.00e+00	1220.00
IUUC-Pva-102533	Pteropus vampyrus	96.84	0.00e+00	756.00
IUUC-Rno-106111	Rattus norvegicus	94.99	0.00e+00	1227.00
IUUC-Sha-106716	Sarcophilus harrisii	83.80	0.00e+00	1073.00
IUUC-Sar-113290	Sorex araneus	45.27	5.00e-88	318.00
IUUC-Ssc-115631	Sus scrofa	46.26	4.00e-135	475.00
IUUC-Tgu-116839	Taeniopygia guttata	85.25	0.00e+00	1106.00
IUUC-Tru-117792	Takifugu rubripes	60.13	0.00e+00	759.00
IUUC-Tsy-119609	Tarsius syrichta	92.03	7.00e-164	570.00
IUUC-Tni-119682	Tetraodon nigroviridis	60.13	0.00e+00	761.00
IUUC-Tme-127039	Tuber melanosporum	31.37	2.00e-12	68.20
IUUC-Tbe-127961	Tupaia belangeri	91.48	0.00e+00	1123.00
IUUC-Ttr-128917	Tursiops truncatus	95.95	0.00e+00	1046.00
IUUC-Vpa-130721	Vicugna pacos	97.64	0.00e+00	865.00
IUUC-Xtr-132233	Xenopus tropicalis	46.04	4.00e-134	471.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence