iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nle-069114

Ensembl Protein ID

ENSNLEP00000010894.1

UniProt Accession

G1RCE5; G1RCE5_NOMLE

Genbank Protein ID

ENSNLEP00000010894

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01119771

Gene Name

NACC2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000008940.1	ENSNLET00000011424.1	ENSNLEP00000010894.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.40e-07	31.7	2	48

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 17   ivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgklde 67
           +vLaasS +F++lf+++     sk+  e+ + v p +f+++l+F+Ytg+l++
   Q: 2    AVLAASSLYFRDLFSGN-----SKSAFELPGsVPPACFQQILSFCYTGRLTM 48
           79************774.....46778***88*****************987 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

XAVLAASSLY FRDLFSGNSK SAFELPGSVP PACFQQILSF CYTGRLTMTA SEQLVVMYTA 60
GFLQIQHIVE RGTDLMFKVS SPHCDSQTAV IEDAGSEPQS PCNQLQPAAA AAPYVVSPSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NGGGCGGTGC TGGCCGCCAG CAGCCTCTAC TTCCGCGACC TGTTCAGCGG CAACAGCAAG 60
AGCGCCTTCG AGCTGCCCGG CTCCGTGCCG CCCGCCTGCT TCCAGCAGAT CCTGTCCTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR018379--BEN_domain
IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ

PROSITE

PS51457--BEN
PS50097--BTB

Pfam

PF10523--BEN
PF00651--BTB

SMART

SM01025--BEN
SM00225--BTB

Gene Ontology

GO:0005739--C:mitochondrion
GO:0000790--C:nuclear chromatin
GO:0005730--C:nucleolus
GO:0016581--C:NuRD complex
GO:0004407--F:histone deacetylase activity
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001076--F:transcription factor activity, RNA polymerase II transcription factor binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0034629--P:cellular protein complex localization
GO:0008285--P:negative regulation of cell proliferation
GO:1900477--P:negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010608--P:posttranscriptional regulation of gene expression
GO:0051260--P:protein homooligomerization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001902	Ailuropoda melanoleuca	88.04	0.00e+00	714.00
IUUC-Apl-004203	Anas platyrhynchos	79.15	0.00e+00	847.00
IUUC-Ame-011046	Astyanax mexicanus	53.40	3.00e-127	448.00
IUUC-Bta-012908	Bos taurus	91.86	0.00e+00	865.00
IUUC-Cja-019140	Callithrix jacchus	95.58	0.00e+00	983.00
IUUC-Cfa-020493	Canis familiaris	93.62	2.00e-172	598.00
IUUC-Cpo-022399	Cavia porcellus	90.64	0.00e+00	944.00
IUUC-Csa-024135	Chlorocebus sabaeus	97.42	0.00e+00	974.00
IUUC-Dre-027761	Danio rerio	70.45	7.00e-81	294.00
IUUC-Dno-029271	Dasypus novemcinctus	76.92	0.00e+00	634.00
IUUC-Ete-032427	Echinops telfairi	86.26	0.00e+00	806.00
IUUC-Eca-033986	Equus caballus	91.90	0.00e+00	922.00
IUUC-Eeu-035211	Erinaceus europaeus	90.06	0.00e+00	896.00
IUUC-Fca-035733	Felis catus	90.42	0.00e+00	809.00
IUUC-Fal-037348	Ficedula albicollis	81.07	0.00e+00	848.00
IUUC-Gmo-039529	Gadus morhua	82.44	7.00e-95	340.00
IUUC-Gga-040405	Gallus gallus	82.32	0.00e+00	874.00
IUUC-Gac-041308	Gasterosteus aculeatus	66.12	2.00e-148	518.00
IUUC-Ggo-044687	Gorilla gorilla	72.53	0.00e+00	702.00
IUUC-Hsa-045955	Homo sapiens	97.79	0.00e+00	945.00
IUUC-Itr-048872	Ictidomys tridecemlineatus	91.19	0.00e+00	900.00
IUUC-Lch-049615	Latimeria chalumnae	73.95	0.00e+00	806.00
IUUC-Loc-051881	Lepisosteus oculatus	66.81	5.00e-171	594.00
IUUC-Laf-054170	Loxodonta africana	87.30	0.00e+00	849.00
IUUC-Mga-059627	Meleagris gallopavo	81.40	0.00e+00	867.00
IUUC-Mdo-063014	Monodelphis domestica	87.22	1.00e-178	619.00
IUUC-Mmu-063897	Mus musculus	92.63	0.00e+00	962.00
IUUC-Mpu-066806	Mustela putorius furo	89.50	0.00e+00	827.00
IUUC-Opr-071127	Ochotona princeps	83.46	8.00e-57	214.00
IUUC-Ont-071693	Oreochromis niloticus	79.65	6.00e-106	377.00
IUUC-Oan-073510	Ornithorhynchus anatinus	84.98	0.00e+00	906.00
IUUC-Ola-086572	Oryzias latipes	62.12	2.00e-157	548.00
IUUC-Oga-088653	Otolemur garnettii	90.77	0.00e+00	946.00
IUUC-Oar-089811	Ovis aries	89.83	0.00e+00	700.00
IUUC-Ptr-090703	Pan troglodytes	99.08	0.00e+00	935.00
IUUC-Pan-092388	Papio anubis	98.35	0.00e+00	999.00
IUUC-Psi-093786	Pelodiscus sinensis	82.50	0.00e+00	882.00
IUUC-Pma-094566	Petromyzon marinus	70.37	1.00e-64	240.00
IUUC-Pfo-096554	Poecilia formosa	60.68	1.00e-152	533.00
IUUC-Pca-101090	Procavia capensis	87.77	0.00e+00	863.00
IUUC-Pva-102843	Pteropus vampyrus	90.24	0.00e+00	887.00
IUUC-Rno-105139	Rattus norvegicus	91.34	0.00e+00	961.00
IUUC-Sha-107545	Sarcophilus harrisii	84.56	0.00e+00	885.00
IUUC-Tgu-117401	Taeniopygia guttata	81.92	0.00e+00	865.00
IUUC-Tru-118080	Takifugu rubripes	64.32	1.00e-140	493.00
IUUC-Tni-120321	Tetraodon nigroviridis	62.74	2.00e-143	502.00
IUUC-Ttr-128369	Tursiops truncatus	93.83	4.00e-179	620.00
IUUC-Xtr-131793	Xenopus tropicalis	75.74	4.00e-121	427.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence