iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033564

Ensembl Protein ID

ENSECAP00000011590.1

UniProt Accession

F7AF18; F7AF18_HORSE

Protein Name

Uncharacterized protein

Gene Name

NOD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000013825.1	ENSECAT00000014494.1	ENSECAP00000011590.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/CARD	86.33	0.00e+00	1556.00	IUUC-Hsa-046886

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Equus caballus

Protein Sequence
(Fasta)

MEKQGHREMG IIPSESHSYI KLLKTNRELL VTHIRNTQCL VDNLLKSDYF SAEDAEIVGA 60
CPTLPDKVRK ILDLVQSKGE EVSEFFLYVL QQLADAYVDL RPWLSEIGFS PSPLIQSKTV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTGCTTAG GTTGCCCTAA GTCAGGAGAC TTTCCTTAAG TTTCTGCCTG TGATGGCAAG 60
AGGTGGAGAT GTCTGTAGGG GTTATTACGG AGAAAGGCTG GGATGAGAAG TCACTGGTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001315--CARD
IPR011029--DEATH-like_dom
IPR001611--Leu-rich_rpt
IPR007111--NACHT_NTPase

PROSITE

PS50209--CARD
PS50837--NACHT

Pfam

PF00619--CARD
PF13516--LRR_6

Gene Ontology

GO:0016323--C:basolateral plasma membrane
GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0071225--P:cellular response to muramyl dipeptide
GO:0050830--P:defense response to Gram-positive bacterium
GO:0016045--P:detection of bacterium
GO:0042228--P:interleukin-8 biosynthetic process
GO:0035556--P:intracellular signal transduction
GO:0002606--P:positive regulation of dendritic cell antigen processing and presentation
GO:0070374--P:positive regulation of ERK1 and ERK2 cascade
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032755--P:positive regulation of interleukin-6 production
GO:0046330--P:positive regulation of JNK cascade
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:1901224--P:positive regulation of NIK/NF-kappaB signaling
GO:0032760--P:positive regulation of tumor necrosis factor production
GO:1904417--P:positive regulation of xenophagy

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001299	Ailuropoda melanoleuca	86.12	0.00e+00	1467.00
IUUC-Apl-003908	Anas platyrhynchos	64.13	0.00e+00	1179.00
IUUC-Aca-005144	Anolis carolinensis	61.78	0.00e+00	1155.00
IUUC-Ame-010829	Astyanax mexicanus	51.36	0.00e+00	908.00
IUUC-Bta-013358	Bos taurus	86.24	0.00e+00	1543.00
IUUC-Cja-019392	Callithrix jacchus	85.17	0.00e+00	1520.00
IUUC-Cfa-020776	Canis familiaris	87.38	0.00e+00	1541.00
IUUC-Cpo-021393	Cavia porcellus	78.15	0.00e+00	1424.00
IUUC-Csa-023872	Chlorocebus sabaeus	86.33	0.00e+00	1575.00
IUUC-Cho-024569	Choloepus hoffmanni	75.22	0.00e+00	629.00
IUUC-Dre-027478	Danio rerio	51.05	0.00e+00	873.00
IUUC-Dno-029231	Dasypus novemcinctus	84.44	0.00e+00	1540.00
IUUC-Dor-030251	Dipodomys ordii	56.06	4.00e-152	531.00
IUUC-Ete-032484	Echinops telfairi	76.34	0.00e+00	796.00
IUUC-Eeu-034456	Erinaceus europaeus	69.04	9.00e-144	503.00
IUUC-Fca-036372	Felis catus	87.38	0.00e+00	1549.00
IUUC-Fal-037418	Ficedula albicollis	63.74	0.00e+00	1180.00
IUUC-Gmo-038740	Gadus morhua	50.91	0.00e+00	902.00
IUUC-Gga-040775	Gallus gallus	63.64	0.00e+00	1209.00
IUUC-Gac-041612	Gasterosteus aculeatus	50.73	0.00e+00	909.00
IUUC-Ggo-045161	Gorilla gorilla	85.82	0.00e+00	1326.00
IUUC-Hsa-046886	Homo sapiens	86.33	0.00e+00	1572.00
IUUC-Itr-048414	Ictidomys tridecemlineatus	83.94	0.00e+00	1596.00
IUUC-Lch-049764	Latimeria chalumnae	60.57	0.00e+00	1041.00
IUUC-Loc-052143	Lepisosteus oculatus	55.61	0.00e+00	1019.00
IUUC-Laf-053503	Loxodonta africana	85.91	0.00e+00	1561.00
IUUC-Mcc-054992	Macaca mulatta	85.91	0.00e+00	1566.00
IUUC-Meu-056406	Macropus eugenii	63.29	0.00e+00	1124.00
IUUC-Mga-059351	Meleagris gallopavo	63.21	0.00e+00	1203.00
IUUC-Mmr-061537	Microcebus murinus	85.17	0.00e+00	1482.00
IUUC-Mdo-061832	Monodelphis domestica	65.60	0.00e+00	1078.00
IUUC-Mmu-064282	Mus musculus	80.11	0.00e+00	1471.00
IUUC-Mpu-066399	Mustela putorius furo	86.86	0.00e+00	1552.00
IUUC-Mlu-067265	Myotis lucifugus	84.58	0.00e+00	1494.00
IUUC-Nle-069078	Nomascus leucogenys	85.59	0.00e+00	1564.00
IUUC-Opr-070946	Ochotona princeps	73.56	0.00e+00	1321.00
IUUC-Ont-071355	Oreochromis niloticus	48.85	0.00e+00	893.00
IUUC-Oan-072937	Ornithorhynchus anatinus	74.04	0.00e+00	1379.00
IUUC-Ocu-073815	Oryctolagus cuniculus	81.18	0.00e+00	1529.00
IUUC-Ola-087381	Oryzias latipes	49.78	0.00e+00	866.00
IUUC-Oga-088725	Otolemur garnettii	84.96	0.00e+00	1554.00
IUUC-Oar-090401	Ovis aries	84.87	0.00e+00	1566.00
IUUC-Ptr-090590	Pan troglodytes	86.12	0.00e+00	1567.00
IUUC-Pan-091765	Papio anubis	86.23	0.00e+00	1571.00
IUUC-Psi-093182	Pelodiscus sinensis	63.38	0.00e+00	1176.00
IUUC-Pfo-097422	Poecilia formosa	48.26	0.00e+00	869.00
IUUC-Pab-098289	Pongo abelii	86.23	0.00e+00	1567.00
IUUC-Pca-100165	Procavia capensis	76.29	0.00e+00	1061.00
IUUC-Pva-102943	Pteropus vampyrus	87.70	0.00e+00	1592.00
IUUC-Rno-104930	Rattus norvegicus	79.60	0.00e+00	1485.00
IUUC-Sce-106428	Saccharomyces cerevisiae	27.14	4.10e+00	28.10
IUUC-Sha-106800	Sarcophilus harrisii	49.07	0.00e+00	687.00
IUUC-Sar-113205	Sorex araneus	74.06	0.00e+00	1009.00
IUUC-Ssc-115910	Sus scrofa	86.39	0.00e+00	1379.00
IUUC-Tgu-117179	Taeniopygia guttata	64.60	0.00e+00	1195.00
IUUC-Tru-118220	Takifugu rubripes	48.89	0.00e+00	859.00
IUUC-Tsy-119418	Tarsius syrichta	81.94	0.00e+00	1222.00
IUUC-Tni-120033	Tetraodon nigroviridis	50.90	2.00e-68	252.00
IUUC-Tbe-127308	Tupaia belangeri	88.80	0.00e+00	650.00
IUUC-Ttr-129233	Tursiops truncatus	87.17	0.00e+00	1576.00
IUUC-Vpa-130620	Vicugna pacos	85.26	4.00e-116	412.00
IUUC-Xtr-132075	Xenopus tropicalis	54.34	0.00e+00	1001.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence