iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132563

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

TNF receptor-associated factor 3

Genbank Nucleotide ID

AAMC01075692

Gene Name

traf3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000012746.4	ENSXETT00000027864.1	ENSXETP00000027864.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	78.35	0.00e+00	952.00	IUUC-Hsa-046957

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MDTGKKTDPS ASVQKANPDR SLATTIYVPE QGGYKERFLK PVEEKYKCEK CRLVLCNPRQ 60
TECGHRFCET CMNAILSSTS PQCMACEDNI TKDKVFKDNC CRREVLALQM FCRNETRGCK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATACTG GCAAAAAGAC CGATCCATCT GCATCTGTGC AAAAAGCCAA CCCAGATCGC 60
AGCCTTGCTA CAACTATCTA TGTGCCAGAA CAAGGAGGAT ACAAGGAAAG GTTTCTAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027128--TRAF3
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF02176--zf-TRAF

SMART

SM00061--MATH

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0042981--P:regulation of apoptotic process
GO:0001817--P:regulation of cytokine production
GO:0050688--P:regulation of defense response to virus
GO:0001878--P:response to yeast
GO:0008063--P:Toll signaling pathway
GO:0033209--P:tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002362	Ailuropoda melanoleuca	79.58	0.00e+00	966.00
IUUC-Apl-004189	Anas platyrhynchos	81.13	0.00e+00	990.00
IUUC-Aca-004540	Anolis carolinensis	79.01	0.00e+00	961.00
IUUC-Acl-008349	Aspergillus clavatus	23.64	3.00e-15	76.30
IUUC-Afu-008782	Aspergillus fumigatus	21.59	3.00e-10	59.70
IUUC-Ani-009190	Aspergillus nidulans	21.75	5.00e-13	68.60
IUUC-Ang-009779	Aspergillus niger	26.36	7.00e-14	71.60
IUUC-Ate-010296	Aspergillus terreus	24.77	1.00e-15	77.40
IUUC-Ame-010645	Astyanax mexicanus	56.13	0.00e+00	647.00
IUUC-Bta-013140	Bos taurus	78.87	0.00e+00	953.00
IUUC-Cja-019436	Callithrix jacchus	78.87	0.00e+00	959.00
IUUC-Cfa-021072	Canis familiaris	79.75	0.00e+00	967.00
IUUC-Cpo-022472	Cavia porcellus	79.23	0.00e+00	957.00
IUUC-Csa-024217	Chlorocebus sabaeus	78.87	0.00e+00	958.00
IUUC-Cho-025066	Choloepus hoffmanni	68.98	0.00e+00	711.00
IUUC-Csv-026078	Ciona savignyi	68.75	1.00e-77	281.00
IUUC-Dre-028208	Danio rerio	52.96	4.00e-174	604.00
IUUC-Dno-028868	Dasypus novemcinctus	79.05	0.00e+00	957.00
IUUC-Dor-031056	Dipodomys ordii	80.66	0.00e+00	840.00
IUUC-Ete-033005	Echinops telfairi	70.32	0.00e+00	692.00
IUUC-Eca-033717	Equus caballus	79.58	0.00e+00	967.00
IUUC-Eeu-035172	Erinaceus europaeus	64.25	1.00e-140	493.00
IUUC-Fca-035688	Felis catus	79.09	0.00e+00	957.00
IUUC-Fal-037176	Ficedula albicollis	80.60	0.00e+00	985.00
IUUC-Gmo-038931	Gadus morhua	54.21	2.00e-168	585.00
IUUC-Gac-042019	Gasterosteus aculeatus	56.32	3.00e-175	608.00
IUUC-Ggo-044424	Gorilla gorilla	78.70	0.00e+00	957.00
IUUC-Hsa-046957	Homo sapiens	78.35	0.00e+00	952.00
IUUC-Itr-048352	Ictidomys tridecemlineatus	79.40	0.00e+00	959.00
IUUC-Kpa-049340	Komagataella pastoris	21.83	4.00e-08	52.40
IUUC-Lch-050680	Latimeria chalumnae	70.91	0.00e+00	843.00
IUUC-Loc-052093	Lepisosteus oculatus	57.35	0.00e+00	674.00
IUUC-Laf-054573	Loxodonta africana	74.74	0.00e+00	893.00
IUUC-Mcc-055049	Macaca mulatta	78.52	0.00e+00	954.00
IUUC-Mga-059244	Meleagris gallopavo	80.95	0.00e+00	987.00
IUUC-Mmr-061469	Microcebus murinus	79.23	0.00e+00	966.00
IUUC-Mdo-063049	Monodelphis domestica	80.25	0.00e+00	979.00
IUUC-Mmu-063763	Mus musculus	79.23	0.00e+00	959.00
IUUC-Mpu-065956	Mustela putorius furo	81.20	0.00e+00	953.00
IUUC-Mlu-067482	Myotis lucifugus	78.35	0.00e+00	952.00
IUUC-Nfi-068511	Neosartorya fischeri	26.48	5.00e-17	82.00
IUUC-Nle-069941	Nomascus leucogenys	79.05	0.00e+00	961.00
IUUC-Opr-071027	Ochotona princeps	68.66	0.00e+00	774.00
IUUC-Ont-071914	Oreochromis niloticus	56.61	0.00e+00	647.00
IUUC-Oan-072802	Ornithorhynchus anatinus	81.66	0.00e+00	983.00
IUUC-Ocu-074075	Oryctolagus cuniculus	78.87	0.00e+00	960.00
IUUC-Ola-086783	Oryzias latipes	34.88	3.00e-91	328.00
IUUC-Oga-088149	Otolemur garnettii	78.87	0.00e+00	964.00
IUUC-Oar-089922	Ovis aries	75.00	0.00e+00	904.00
IUUC-Ptr-091412	Pan troglodytes	78.52	0.00e+00	955.00
IUUC-Pan-092789	Papio anubis	78.87	0.00e+00	958.00
IUUC-Psi-093603	Pelodiscus sinensis	80.78	0.00e+00	975.00
IUUC-Pma-094463	Petromyzon marinus	49.16	1.00e-142	499.00
IUUC-Pfo-096518	Poecilia formosa	56.01	0.00e+00	640.00
IUUC-Pab-097664	Pongo abelii	78.70	0.00e+00	957.00
IUUC-Pca-100821	Procavia capensis	74.28	0.00e+00	759.00
IUUC-Pva-103201	Pteropus vampyrus	69.89	0.00e+00	830.00
IUUC-Rno-105505	Rattus norvegicus	78.87	0.00e+00	952.00
IUUC-Sha-107416	Sarcophilus harrisii	80.25	0.00e+00	979.00
IUUC-Sar-113438	Sorex araneus	75.27	9.00e-84	303.00
IUUC-Ssc-115351	Sus scrofa	79.40	0.00e+00	963.00
IUUC-Tgu-116608	Taeniopygia guttata	81.42	0.00e+00	969.00
IUUC-Tru-117964	Takifugu rubripes	54.50	0.00e+00	631.00
IUUC-Tni-120211	Tetraodon nigroviridis	55.87	0.00e+00	629.00
IUUC-Ttr-128450	Tursiops truncatus	72.19	5.00e-142	496.00
IUUC-Vpa-130074	Vicugna pacos	82.95	0.00e+00	775.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence