iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-120037

UUCD1 version

UUC-TeN-00741

Ensembl Protein ID

ENSTNIP00000017261.1

UniProt Accession

H3D9S0; H3D9S0_TETNG

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000014247.1	ENSTNIT00000017479.1	ENSTNIP00000017261.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.80e-126	421.7	408	743

Active Site

Position(s)	Description	Evidence
712	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dlkkrl+v+f+gEegld+gGv+re+l+ll++e+ np++glf+ys ++ +tlq+npds + np+hl++F+f+Gr++g+a++++++++ 
   Q: 408  PKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYTLQINPDSSI-NPDHLSYFHFVGRVMGLAVFHSHYING 495
           689*********************************************************9.89************************* PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvve 179
            ++++fyk+llgk+++l+dle++dpel+ksl +i+en   di+   ld tf+v+++ +g+ +++eLkp+G+n  Vt+eNk+eYv+l+v+
   Q: 496  SFTQPFYKQLLGKPIQLSDLESTDPELHKSLVWILEN---DITSV-LDHTFCVEHNAFGKLSQHELKPNGRNLAVTEENKKEYVRLYVN 580
           ***********************************99...99998.******************************************* PP
   S: 180  yrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFv 268
           +r+ +gi+ q+ a+++Gf+e+ip++ll+ F+++elel+i G  +id+ d+k++t+ k+ +t++s++++wFw+++e+fs+e r ++LqFv
   Q: 581  WRFMRGIEAQFLALQKGFSELIPQHLLKPFDHKELELIIGGLGKIDIADWKSNTRLKH-CTSESNVVRWFWQAVEAFSEERRGRLLQFV 668
           ********************************************************99.****************************** PP
   S: 269  TgssrlPlgGfaelk.......prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           Tgs r+Pl+Gf++l+       prlf+i+  da++d+lP+++TCfn++++P Y+s+e+l+ekLl+A+eet gF +
   Q: 669  TGSTRVPLQGFKALQgstgsagPRLFTIHLiDANTDNLPKAHTCFNRIDVPSYESYEKLYEKLLTAVEETCGFAV 743
           ******************************99999**************************************76 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MSNPGSRRSG SSIKIRLTVL CAKNLAKKDF FRLPDPFAKV VVDGSGQCHS TDTVKSTLDP 60
KWNQHYDLYI GKTDSITISI WNHKKIHKRQ GAGFLGCIRL LSNAISRLKD TGYQRLDLCK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGAATC CTGGGAGTCG GAGGAGCGGG TCCAGCATCA AAATCCGACT GACAGGTAAA 60
AGCCAGGCAG AAATGAAACA AAAGCTCAGT GTGTGTTTTA GCGGGGCCCA GAGAAGCACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004155	Anas platyrhynchos	81.73	0.00e+00	1231.00
IUUC-Aca-005238	Anolis carolinensis	81.42	0.00e+00	1222.00
IUUC-Ame-010901	Astyanax mexicanus	85.47	0.00e+00	1304.00
IUUC-Cja-018985	Callithrix jacchus	82.01	0.00e+00	1254.00
IUUC-Cfa-020568	Canis familiaris	80.10	0.00e+00	1208.00
IUUC-Cpo-022531	Cavia porcellus	81.62	0.00e+00	1251.00
IUUC-Csa-024145	Chlorocebus sabaeus	82.06	0.00e+00	1246.00
IUUC-Dre-028341	Danio rerio	85.34	0.00e+00	1305.00
IUUC-Dno-029705	Dasypus novemcinctus	79.89	0.00e+00	1189.00
IUUC-Dor-030314	Dipodomys ordii	91.78	2.00e-121	429.00
IUUC-Dme-031740	Drosophila melanogaster	71.50	1.00e-172	600.00
IUUC-Eca-034125	Equus caballus	81.31	0.00e+00	1215.00
IUUC-Gga-040218	Gallus gallus	82.56	0.00e+00	1264.00
IUUC-Gac-041707	Gasterosteus aculeatus	92.25	0.00e+00	1345.00
IUUC-Ggo-045408	Gorilla gorilla	77.17	0.00e+00	1126.00
IUUC-Hsa-045878	Homo sapiens	82.14	0.00e+00	1256.00
IUUC-Itr-048317	Ictidomys tridecemlineatus	80.72	0.00e+00	1219.00
IUUC-Loc-052628	Lepisosteus oculatus	78.47	0.00e+00	1258.00
IUUC-Mcc-055479	Macaca mulatta	75.07	0.00e+00	1100.00
IUUC-Mdo-063005	Monodelphis domestica	82.30	0.00e+00	1257.00
IUUC-Mmu-063634	Mus musculus	81.93	0.00e+00	1233.00
IUUC-Mlu-067584	Myotis lucifugus	80.45	0.00e+00	1219.00
IUUC-Nle-069033	Nomascus leucogenys	81.98	0.00e+00	1225.00
IUUC-Ont-072265	Oreochromis niloticus	90.79	0.00e+00	1376.00
IUUC-Ola-086960	Oryzias latipes	80.84	0.00e+00	1178.00
IUUC-Oga-088579	Otolemur garnettii	82.01	0.00e+00	1256.00
IUUC-Oar-090396	Ovis aries	80.61	0.00e+00	1165.00
IUUC-Ptr-091624	Pan troglodytes	82.14	0.00e+00	1256.00
IUUC-Pan-092479	Papio anubis	81.84	0.00e+00	1222.00
IUUC-Pfo-097203	Poecilia formosa	92.11	0.00e+00	1360.00
IUUC-Pab-097540	Pongo abelii	81.74	0.00e+00	1191.00
IUUC-Pca-100379	Procavia capensis	62.63	7.00e-157	547.00
IUUC-Rno-105396	Rattus norvegicus	81.93	0.00e+00	1233.00
IUUC-Sha-107216	Sarcophilus harrisii	80.81	0.00e+00	1235.00
IUUC-Ssc-116413	Sus scrofa	80.42	0.00e+00	1194.00
IUUC-Tgu-116723	Taeniopygia guttata	81.44	0.00e+00	1206.00
IUUC-Tru-117843	Takifugu rubripes	89.95	0.00e+00	1363.00
IUUC-Tbe-127879	Tupaia belangeri	68.09	0.00e+00	977.00
IUUC-Xtr-132237	Xenopus tropicalis	79.71	0.00e+00	1223.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence