iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-007644

UUCD1 version

UUC-ArT-01595

Ensembl Protein ID

AT3G46460.1

UniProt Accession

Q42541; Q4TYZ7; UBC13_ARATH

Genbank Protein ID

AAC49322.1; AAY44853.1; CAB62037.1; AEE78162.1; AAK91385.1; AAM16196.1

Protein Name

Ubiquitin-conjugating enzyme E2 13; E2 ubiquitin-conjugating enzyme 13; Ubiquitin carrier protein 13; Ubiquitin-protein ligase 13

Genbank Nucleotide ID

U33758; DQ027027; AL133298; CP002686; AY050368; AY094040

Gene Name

UBC13; At3g46460; F18L15.180

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT3G46460	AT3G46460.1	AT3G46460.1
AT3G46460	AT3G46460.2	AT3G46460.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E2/UBC	E2_UBC	18178771

Classification

Family	E-value	Score	Start	End
E2/UBC	2.10e-49	167.7	9	156

Active Site

Position(s)	Description	Evidence
89	Glycyl thioester intermediate	{ECO:0000255\|PROSITE-ProRule:PRU00388, ECO:0000255\|PROSITE-ProRule:PRU10133}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk...........e 88
           l+k+lk+l k+p++g+sa++vde++++ew+v+i+Gp+dt Yegg+F + ++fp++YP +PP+v+f++ i+hPnvy++G+vC+sil+            
   Q: 9    LQKQLKDLCKHPVDGFSAGLVDEKNIFEWSVTIIGPPDTLYEGGFFYAIMSFPQNYPNSPPTVRFTSDIWHPNVYPDGRVCISILHppgddpsgyelA 106
           799**********************************************************************************999999999*999 PP
   S: 89   eekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           +e+W+p+++ves++lsi+s+l+ pn esp+n+eaa++++++r e+kkkv+
   Q: 107  SERWTPVHTVESIMLSIISMLSGPNDESPANVEAAKEWREKRDEFKKKVS 156
           ***********************************************996 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Involved in the formation of multiubiquitin chains. Signal the protein for selective degradation.

Protein Sequence
(Fasta)

MNSQACLLLQ KQLKDLCKHP VDGFSAGLVD EKNIFEWSVT IIGPPDTLYE GGFFYAIMSF 60
PQNYPNSPPT VRFTSDIWHP NVYPDGRVCI SILHPPGDDP SGYELASERW TPVHTVESIM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAAAAAAAA AAAAAATCCC CAGTTTCCAT CTTTTTTGAA CCTTCTCGAT ATAAAGCTCT 60
CTATTCAATT CCCATCTCTA TCTTCTTCCT CTTCATCTTC CTCTTCTCTC AGATCACTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0000209--P:protein polyubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ath:AT3G46460

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000411	Aegilops tauschii	64.97	2.00e-62	230.00
IUUC-Aly-005673	Arabidopsis lyrata	100.00	1.00e-80	291.00
IUUC-Acl-008080	Aspergillus clavatus	59.31	7.00e-49	185.00
IUUC-Afl-008660	Aspergillus flavus	62.41	7.00e-49	185.00
IUUC-Afu-009051	Aspergillus fumigatus	56.44	7.00e-49	185.00
IUUC-Ani-009271	Aspergillus nidulans	61.42	2.00e-43	167.00
IUUC-Ang-009748	Aspergillus niger	55.83	2.00e-48	183.00
IUUC-Aor-009951	Aspergillus oryzae	62.41	7.00e-49	185.00
IUUC-Ate-010293	Aspergillus terreus	56.44	6.00e-49	185.00
IUUC-Ame-011698	Astyanax mexicanus	59.72	1.00e-51	194.00
IUUC-Bgr-012226	Blumeria graminis	55.00	9.00e-46	175.00
IUUC-Bci-013676	Botrytis cinerea	57.34	9.00e-48	181.00
IUUC-Bdi-014844	Brachypodium distachyon	87.16	2.00e-70	257.00
IUUC-Cel-018162	Caenorhabditis elegans	67.59	1.00e-57	214.00
IUUC-Cpo-022207	Cavia porcellus	64.86	1.00e-56	211.00
IUUC-Cho-024621	Choloepus hoffmanni	37.16	1.00e-22	99.40
IUUC-Cgl-026553	Colletotrichum gloeosporioides	56.85	2.00e-49	187.00
IUUC-Dse-031253	Dothistroma septosporum	54.94	9.00e-50	188.00
IUUC-Dme-032132	Drosophila melanogaster	69.66	2.00e-59	220.00
IUUC-Ete-032885	Echinops telfairi	64.86	1.00e-56	211.00
IUUC-Eeu-035128	Erinaceus europaeus	52.03	8.00e-39	152.00
IUUC-Fox-037762	Fusarium oxysporum	54.04	5.00e-49	185.00
IUUC-Fso-038181	Fusarium solani	52.80	3.00e-48	183.00
IUUC-Ggr-039808	Gaeumannomyces graminis	56.85	2.00e-49	187.00
IUUC-Hvu-047065	Hordeum vulgare	86.00	4.00e-71	260.00
IUUC-Mor-057260	Magnaporthe oryzae	57.53	1.00e-49	187.00
IUUC-Mpo-057468	Magnaporthe poae	56.85	1.00e-49	188.00
IUUC-Mpu-066561	Mustela putorius furo	63.58	4.00e-57	213.00
IUUC-Nfi-068395	Neosartorya fischeri	56.44	7.00e-49	185.00
IUUC-Ncr-068623	Neurospora crassa	57.53	1.00e-48	184.00
IUUC-Opr-070958	Ochotona princeps	64.86	1.00e-56	211.00
IUUC-Oba-075915	Oryza barthii	89.19	7.00e-79	285.00
IUUC-Ogl-076981	Oryza glaberrima	89.19	7.00e-79	285.00
IUUC-Ogu-078183	Oryza glumaepatula	89.19	7.00e-79	285.00
IUUC-Oin-079755	Oryza indica	89.19	7.00e-79	285.00
IUUC-Olo-080576	Oryza longistaminata	89.19	7.00e-79	285.00
IUUC-Ome-081190	Oryza meridionalis	84.08	1.00e-76	278.00
IUUC-Oni-083010	Oryza nivara	89.19	7.00e-79	285.00
IUUC-Oru-084817	Oryza rufipogon	89.19	7.00e-79	285.00
IUUC-Osa-085291	Oryza sativa	89.19	7.00e-79	285.00
IUUC-Ptr-091331	Pan troglodytes	64.86	1.00e-56	211.00
IUUC-Pma-094602	Petromyzon marinus	60.29	2.00e-48	183.00
IUUC-Pop-099940	Populus trichocarpa	88.00	3.00e-72	263.00
IUUC-Pgr-103274	Puccinia graminis	62.16	1.00e-42	164.00
IUUC-Spo-108104	Schizosaccharomyces pombe	68.46	4.00e-60	222.00
IUUC-Ssl-108636	Sclerotinia sclerotiorum	55.94	1.00e-47	181.00
IUUC-Tru-117873	Takifugu rubripes	65.54	3.00e-57	213.00
IUUC-Tre-122131	Trichoderma reesei	56.55	9.00e-48	181.00
IUUC-Tvi-122669	Trichoderma virens	57.93	2.00e-49	187.00
IUUC-Tbe-127917	Tupaia belangeri	64.86	1.00e-56	211.00
IUUC-Ttr-128609	Tursiops truncatus	64.86	3.00e-56	211.00
IUUC-Vda-129914	Verticillium dahliae	57.93	1.00e-49	187.00
IUUC-Xtr-131942	Xenopus tropicalis	64.86	1.00e-56	211.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence