iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-035403

Ensembl Protein ID

ENSFCAP00000013637.3

UniProt Accession

M3WL63; M3WL63_FELCA

Genbank Protein ID

ENSFCAP00000013637

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02167584

Gene Name

SQSTM1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000014700.3	ENSFCAT00000014704.3	ENSFCAP00000013637.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/PB1	3.10e-16	59.4	22	106

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/PB1

   S: 3    rvkvsykgeirs....faldlekpgkfedLlkavrt.ltelknsevalkYeDedGDlvtlksDedldkavsllaskksllrlliqkk 84
           r+ +++++e+++     a+ +++pg +e+Ll++v++ +++l+   ++ +Y+DedGDlv+++sDe+l++a+s+   k++++r++i++k
   Q: 22   RFSFCFSPEPEAeaeaEAEVAAGPGPCERLLSRVAAlFPALRPGGFQTHYRDEDGDLVAFSSDEELTMAMSY--VKDDIFRIYIKEK 106
           8999999999998888777789**************999********************************7..9*********975 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MASLTVKAYL LGKEDAAREI RRFSFCFSPE PEAEAEAEAE VAAGPGPCER LLSRVAALFP 60
ALRPGGFQTH YRDEDGDLVA FSSDEELTMA MSYVKDDIFR IYIKEKKECR RDHRPPCAQE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGATGGCGTC GCTCACCGTC AAGGCCTACC TTCTGGGCAA GGAGGACGCG GCCCGTGAGA 60
TCCGCCGCTT CAGCTTCTGC TTCAGCCCAG AACCCGAGGC GGAGGCGGAG GCCGAGGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000270--PB1_dom
IPR033741--SQSTM_UBA
IPR015940--UBA
IPR009060--UBA-like
IPR000433--Znf_ZZ

PROSITE

PS51745--PB1
PS50030--UBA
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF00564--PB1
PF16577--UBA_5
PF00569--ZZ

SMART

SM00666--PB1
SM00165--UBA
SM00291--ZnF_ZZ

Gene Ontology

GO:0016235--C:aggresome
GO:0044753--C:amphisome
GO:0044754--C:autolysosome
GO:0005776--C:autophagosome
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0000932--C:P-body
GO:0016605--C:PML body
GO:0000407--C:pre-autophagosomal structure
GO:0097225--C:sperm midpiece
GO:0042802--F:identical protein binding
GO:0043130--F:ubiquitin binding
GO:0008270--F:zinc ion binding
GO:0006914--P:autophagy
GO:0044130--P:negative regulation of growth of symbiont in host
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0016239--P:positive regulation of macroautophagy
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043122--P:regulation of I-kappaB kinase/NF-kappaB signaling
GO:0061635--P:regulation of protein complex stability
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

fca:101085431

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001367	Ailuropoda melanoleuca	94.89	0.00e+00	632.00
IUUC-Apl-003897	Anas platyrhynchos	59.06	8.00e-117	413.00
IUUC-Aca-004699	Anolis carolinensis	47.74	5.00e-97	347.00
IUUC-Ame-010982	Astyanax mexicanus	45.10	1.00e-64	240.00
IUUC-Bta-012634	Bos taurus	89.64	0.00e+00	748.00
IUUC-Cel-018660	Caenorhabditis elegans	45.45	1.00e-10	59.30
IUUC-Cja-019684	Callithrix jacchus	89.64	0.00e+00	720.00
IUUC-Cfa-020573	Canis familiaris	89.35	1.00e-148	519.00
IUUC-Cpo-021425	Cavia porcellus	78.97	3.00e-178	617.00
IUUC-Csa-023968	Chlorocebus sabaeus	88.96	0.00e+00	701.00
IUUC-Cho-024596	Choloepus hoffmanni	83.87	3.00e-51	195.00
IUUC-Cin-025557	Ciona intestinalis	27.92	2.00e-13	70.10
IUUC-Csv-025974	Ciona savignyi	25.42	9.00e-13	67.40
IUUC-Dre-028621	Danio rerio	44.05	3.00e-94	338.00
IUUC-Dno-029060	Dasypus novemcinctus	86.61	0.00e+00	731.00
IUUC-Dor-030547	Dipodomys ordii	87.27	1.00e-136	479.00
IUUC-Dme-031659	Drosophila melanogaster	50.00	4.00e-10	59.70
IUUC-Ete-033201	Echinops telfairi	79.47	7.00e-162	563.00
IUUC-Eca-033456	Equus caballus	90.86	0.00e+00	679.00
IUUC-Eeu-035157	Erinaceus europaeus	85.03	4.00e-172	597.00
IUUC-Fal-036798	Ficedula albicollis	56.81	2.00e-133	468.00
IUUC-Gmo-039619	Gadus morhua	39.64	5.00e-46	177.00
IUUC-Gga-040137	Gallus gallus	57.02	5.00e-132	464.00
IUUC-Gac-042410	Gasterosteus aculeatus	45.30	1.00e-94	339.00
IUUC-Ggo-044690	Gorilla gorilla	90.54	0.00e+00	708.00
IUUC-Hsa-046390	Homo sapiens	90.54	0.00e+00	705.00
IUUC-Itr-048536	Ictidomys tridecemlineatus	90.77	0.00e+00	766.00
IUUC-Lch-049658	Latimeria chalumnae	47.25	4.00e-111	394.00
IUUC-Loc-052589	Lepisosteus oculatus	46.22	4.00e-109	387.00
IUUC-Laf-053746	Loxodonta africana	79.73	0.00e+00	636.00
IUUC-Mcc-055635	Macaca mulatta	88.96	0.00e+00	709.00
IUUC-Meu-056528	Macropus eugenii	51.75	2.00e-106	379.00
IUUC-Mga-059458	Meleagris gallopavo	58.44	2.00e-118	418.00
IUUC-Mvi-060347	Microbotryum violaceum	54.05	1.00e-07	52.40
IUUC-Mmr-061539	Microcebus murinus	85.36	3.00e-136	477.00
IUUC-Mdo-063083	Monodelphis domestica	63.60	1.00e-149	522.00
IUUC-Mmu-063589	Mus musculus	85.65	0.00e+00	720.00
IUUC-Mpu-065727	Mustela putorius furo	93.26	0.00e+00	667.00
IUUC-Mlu-067026	Myotis lucifugus	88.53	0.00e+00	639.00
IUUC-Nle-069356	Nomascus leucogenys	64.47	8.00e-118	416.00
IUUC-Opr-071091	Ochotona princeps	67.37	6.00e-94	337.00
IUUC-Ont-071864	Oreochromis niloticus	46.86	2.00e-99	355.00
IUUC-Oan-073308	Ornithorhynchus anatinus	61.23	4.00e-131	461.00
IUUC-Ocu-074110	Oryctolagus cuniculus	89.19	0.00e+00	717.00
IUUC-Ola-086944	Oryzias latipes	45.00	2.00e-39	154.00
IUUC-Oga-088869	Otolemur garnettii	87.56	0.00e+00	712.00
IUUC-Oar-089857	Ovis aries	90.67	0.00e+00	649.00
IUUC-Ptr-091640	Pan troglodytes	90.77	0.00e+00	709.00
IUUC-Pan-092831	Papio anubis	88.89	0.00e+00	702.00
IUUC-Psi-093925	Pelodiscus sinensis	55.95	7.00e-126	443.00
IUUC-Pma-094576	Petromyzon marinus	31.27	3.00e-30	125.00
IUUC-Pfo-097297	Poecilia formosa	43.78	3.00e-89	322.00
IUUC-Pab-098725	Pongo abelii	81.41	6.00e-180	623.00
IUUC-Pca-101106	Procavia capensis	87.61	0.00e+00	687.00
IUUC-Pva-102710	Pteropus vampyrus	88.27	0.00e+00	641.00
IUUC-Rno-105539	Rattus norvegicus	87.00	0.00e+00	736.00
IUUC-Sha-107469	Sarcophilus harrisii	59.48	2.00e-123	435.00
IUUC-Ssc-115526	Sus scrofa	90.54	0.00e+00	726.00
IUUC-Tgu-117194	Taeniopygia guttata	60.05	8.00e-116	409.00
IUUC-Tru-117896	Takifugu rubripes	47.79	3.00e-100	358.00
IUUC-Tni-119943	Tetraodon nigroviridis	47.53	1.00e-91	330.00
IUUC-Ttr-128676	Tursiops truncatus	89.19	0.00e+00	753.00
IUUC-Vda-129812	Verticillium dahliae	36.36	7.00e-08	52.40
IUUC-Vpa-130319	Vicugna pacos	95.00	2.00e-56	212.00
IUUC-Xtr-132907	Xenopus tropicalis	51.85	1.00e-125	443.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence