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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-064033
UUCD1 version UUC-MuM-00076
Ensembl Protein ID ENSMUSP00000029444.6
UniProt Accession E9QP19; E9QP19_MOUSE
Genbank Protein ID ENSMUSP00000029444
Protein Name E3 ubiquitin-protein ligase TRIM33
Genbank Nucleotide ID AC164089
Gene Name Trim33
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000033014.12 ENSMUST00000029444.12 ENSMUSP00000029444.6
ENSMUSG00000033014.12 ENSMUST00000106860.5 ENSMUSP00000102473.1
ENSMUSG00000033014.12 ENSMUST00000197779.4 ENSMUSP00000143749.1
ENSMUSG00000033014.12 ENSMUST00000198706.1 ENSMUSP00000142585.1
ENSMUSG00000033014.12 ENSMUST00000197365.1 ENSMUSP00000143117.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitecircBasemiRTarBasemicroRNA
TRANSFACRepTarmiRNAMapRAID2
Post-translational Modifications (PTMs)
PHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 6.90e-09 36.9 901 946
E3 activity/RING/RING 1.00e-05 27.0 139 199
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C+vC++gg+    l++CekC ++fH +C+ ++   ++p+ + wiC+ Cr+
   Q: 901  DWCAVCQNGGD----LLCCEKCPKVFHLTCHVPT-LLSFPSGD-WICTFCRD 946
           79*********....*******************.*******7.******85 PP
   

   E3 activity/RING/RING
   S: 1    CaiCledf....kdgplvlpCgHvfhadCl...qkw........pglknssskefrCPlCr 46
           Ca+C++++    + +p++lpC H f++ Cl   ++          +   ++ + +rCP+Cr
   Q: 139  CAVCQQSLqsrrEAEPKLLPCLHSFCLRCLpepERQlsvpipggSNGDVQQVGVIRCPVCR 199
           ******999888556***************88844468888766444445667779****8 PP
   
Organism Mus musculus
Protein Sequence
(Fasta)
MAENKGGGEA ESGGGGSGSA PVTAGAAGPT AQEAEPPLAA VLVEEEEEEG GRAGAEGGAA 60
GPDDGGVAAA SSSSAPAASV PAASVGSAVP GGAASTPAPA AAPAPAPAPA PAPAPAPAPA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-064033|E3,PHD;E3,RING|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CAGCAACACC CAGCGAAGAC CCAGGTGGTC CGCACCTCCT CGGTAGGAGG CCTCCGCGAC 60
CAAGCGCGCG ACAGGTGAAG CTTCCGCGGT GGCGCGCCCG TCGCTGGGGA TGGCGTCGCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-064033|E3,PHD;E3,RING|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR003649--Bbox_C
IPR001487--Bromodomain
IPR019786--Zinc_finger_PHD-type_CS
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS50014--BROMODOMAIN_2
PS50119--ZF_BBOX
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF00439--Bromodomain
PF00628--PHD
PF00643--zf-B_box
PF13445--zf-RING_UBOX
PRINTS

PR00503--BROMODOMAIN
SMART

SM00502--BBC
SM00336--BBOX
SM00297--BROMO
SM00249--PHD
SM00184--RING
Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0030514--P:negative regulation of BMP signaling pathway
GO:0016567--P:protein ubiquitination
GO:0017015--P:regulation of transforming growth factor beta receptor signaling pathway
KEGG mmu:94093
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002364 Ailuropoda melanoleuca 95.84 0.00e+00 1711.00
IUUC-Apl-003894 Anas platyrhynchos 90.21 0.00e+00 1576.00
IUUC-Aca-004658 Anolis carolinensis 89.10 0.00e+00 1544.00
IUUC-Ame-011619 Astyanax mexicanus 60.26 0.00e+00 1048.00
IUUC-Bta-013341 Bos taurus 94.34 0.00e+00 1668.00
IUUC-Cja-018733 Callithrix jacchus 97.12 0.00e+00 1741.00
IUUC-Cfa-020725 Canis familiaris 96.58 0.00e+00 1689.00
IUUC-Cpo-021833 Cavia porcellus 96.13 0.00e+00 1712.00
IUUC-Csa-023040 Chlorocebus sabaeus 96.82 0.00e+00 1683.00
IUUC-Cho-024934 Choloepus hoffmanni 94.11 0.00e+00 1599.00
IUUC-Cin-025200 Ciona intestinalis 43.78 6.00e-45 176.00
IUUC-Csv-026278 Ciona savignyi 47.25 5.00e-20 91.30
IUUC-Dre-027797 Danio rerio 73.25 4.00e-173 602.00
IUUC-Dno-028955 Dasypus novemcinctus 96.43 0.00e+00 1774.00
IUUC-Dme-032143 Drosophila melanogaster 31.69 9.00e-45 176.00
IUUC-Ete-032728 Echinops telfairi 93.43 0.00e+00 898.00
IUUC-Eca-033573 Equus caballus 96.13 0.00e+00 1702.00
IUUC-Eeu-035138 Erinaceus europaeus 85.39 0.00e+00 820.00
IUUC-Fca-035776 Felis catus 96.43 0.00e+00 1599.00
IUUC-Fal-037583 Ficedula albicollis 90.02 0.00e+00 1609.00
IUUC-Gmo-039353 Gadus morhua 62.03 0.00e+00 661.00
IUUC-Gga-040874 Gallus gallus 90.98 0.00e+00 1686.00
IUUC-Gac-041689 Gasterosteus aculeatus 55.93 0.00e+00 1102.00
IUUC-Ggo-045151 Gorilla gorilla 94.82 0.00e+00 1300.00
IUUC-Hsa-046169 Homo sapiens 96.82 0.00e+00 1683.00
IUUC-Itr-048377 Ictidomys tridecemlineatus 95.23 0.00e+00 731.00
IUUC-Lch-050411 Latimeria chalumnae 80.65 0.00e+00 1360.00
IUUC-Loc-051992 Lepisosteus oculatus 72.40 0.00e+00 1285.00
IUUC-Laf-054552 Loxodonta africana 96.44 0.00e+00 1625.00
IUUC-Mcc-055744 Macaca mulatta 96.82 0.00e+00 1682.00
IUUC-Meu-056647 Macropus eugenii 98.60 0.00e+00 715.00
IUUC-Mga-059589 Meleagris gallopavo 89.93 0.00e+00 950.00
IUUC-Mmr-060727 Microcebus murinus 97.21 0.00e+00 1720.00
IUUC-Mdo-063029 Monodelphis domestica 94.44 0.00e+00 1733.00
IUUC-Mpu-066679 Mustela putorius furo 96.23 0.00e+00 1707.00
IUUC-Mlu-067286 Myotis lucifugus 95.90 0.00e+00 1607.00
IUUC-Nle-069156 Nomascus leucogenys 96.54 0.00e+00 1688.00
IUUC-Opr-070309 Ochotona princeps 85.42 0.00e+00 1261.00
IUUC-Ont-071586 Oreochromis niloticus 55.57 0.00e+00 1047.00
IUUC-Oan-073205 Ornithorhynchus anatinus 92.55 0.00e+00 1425.00
IUUC-Ocu-074667 Oryctolagus cuniculus 94.40 0.00e+00 1599.00
IUUC-Ola-086481 Oryzias latipes 51.42 0.00e+00 945.00
IUUC-Oga-089101 Otolemur garnettii 96.43 0.00e+00 1707.00
IUUC-Oar-090167 Ovis aries 95.93 0.00e+00 1717.00
IUUC-Ptr-090901 Pan troglodytes 96.92 0.00e+00 1686.00
IUUC-Pan-092448 Papio anubis 94.74 0.00e+00 1679.00
IUUC-Psi-093657 Pelodiscus sinensis 90.27 0.00e+00 1456.00
IUUC-Pma-094506 Petromyzon marinus 65.91 1.00e-50 191.00
IUUC-Pfo-097104 Poecilia formosa 69.23 3.00e-160 559.00
IUUC-Pab-097704 Pongo abelii 96.82 0.00e+00 1716.00
IUUC-Pca-101001 Procavia capensis 86.02 0.00e+00 636.00
IUUC-Pva-102733 Pteropus vampyrus 92.10 0.00e+00 1538.00
IUUC-Rno-105512 Rattus norvegicus 99.01 0.00e+00 1775.00
IUUC-Sha-107423 Sarcophilus harrisii 93.22 0.00e+00 1606.00
IUUC-Sar-113181 Sorex araneus 87.62 5.00e-143 501.00
IUUC-Ssc-116330 Sus scrofa 91.08 0.00e+00 1491.00
IUUC-Tgu-117388 Taeniopygia guttata 75.80 0.00e+00 1252.00
IUUC-Tru-118728 Takifugu rubripes 55.50 0.00e+00 971.00
IUUC-Tsy-119053 Tarsius syrichta 97.62 0.00e+00 1035.00
IUUC-Tni-120279 Tetraodon nigroviridis 46.62 3.00e-162 565.00
IUUC-Tbe-127573 Tupaia belangeri 85.77 0.00e+00 815.00
IUUC-Ttr-128594 Tursiops truncatus 96.43 0.00e+00 1718.00
IUUC-Vpa-130619 Vicugna pacos 89.22 0.00e+00 1074.00
IUUC-Xtr-132837 Xenopus tropicalis 84.07 0.00e+00 1486.00
Created Date 25-Jun-2017

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