iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-120374

UUCD1 version

UUC-TeN-00752

Ensembl Protein ID

ENSTNIP00000013567.1

UniProt Accession

H3CZ82; H3CZ82_TETNG

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000010652.1	ENSTNIT00000013761.1	ENSTNIP00000013567.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.60e-86	289.8	4438	4767

Active Site

Position(s)	Description	Evidence
4736	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 7    krlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp.....ehlklFeflGrllgkalqdgrll 88
           ++++v+fvgE++ d+gG  +e +a++++elqn  ++l+  ++n++ +   n+d +l np      h+++F+flG+llg+a+++g +l
   Q: 4438 RVWKVKFVGESVDDCGGGYSESIAEMCEELQNGLTPLLIVTPNGRDESGANRDCFLLNPaakspLHMSMFRFLGVLLGIAIRTGSPL 4524
           4566****************************************9999*******999999999*********************** PP
   S: 89   dlplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvk 175
            l+l+++++k+l g +l++ dl+evd++++ sl++i++n+ +  e ++++l f+     +++++ +++  +++  ++t eN+ eYv+
   Q: 4525 SLNLAEPVWKQLAGMNLTIADLSEVDKDFIPSLMYIRDNEATAEEFEAMTLPFT-----VPNASGQDIQLSSKYSHITLENRAEYVR 4606
           ***************************************998999999999998.....7889999999****************** PP
   S: 176  lvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerk 262
           l ++yrl+e ++eqv a+reG+ +v+p  llslFt  ele+++cG+++i ++ lk+ ++ykg ++++s  iqwFwev+e+fs++er+
   Q: 4607 LAINYRLHE-FDEQVSAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKG-VEPTSALIQWFWEVMESFSNTERS 4691
           *********.**************************************************77.************************ PP
   S: 263  afLqFvTgssrlPlgGfaelkprlfvirk....dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
            fL+Fv+g+ rlP + +a+++ r fv++     +  d+ lP+s TCf++LkLP+Ys k++l+ekL yAi+ +k++++
   Q: 4692 LFLRFVWGRTRLP-RTIADFRGRDFVVQVldkyNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDT 4767
           *************.8*************999988888***********************************99875 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MPSPSFTLDA QLRFHDKWLK IDLQRAFSPQ GLSEMWNEMV IDEEITFNRE ESAHTGTALH 60
LQNPTHGAQN SGSKKDEPND KEKKEDEDML TSAHHSIIET WDWGRQPDES ELKECLAVLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCTTCTC CCTCCTTTAC CCTCGATGCT CAGCTCAGAT TCCACGACAA GTGGCTGAAG 60
ATAGATTTAC AGGTATGTCG TCTAAAAATT CCCAATTCTT CCTGTTTTTC TTTCTCGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR004939--APC_su10/DOC_dom
IPR006624--Beta-propeller_rpt_TECPR
IPR021097--CPH_domain
IPR001199--Cyt_B5-like_heme/steroid-bd
IPR008979--Galactose-bd-like
IPR000569--HECT_dom
IPR010606--Mib_Herc2
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens
IPR014722--Rib_L2_dom2
IPR000433--Znf_ZZ

PROSITE

PS50255--CYTOCHROME_B5_2
PS51284--DOC
PS50237--HECT
PS51416--MIB_HERC2
PS00626--RCC1_2
PS50012--RCC1_3
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF03256--ANAPC10
PF11515--Cul7
PF00173--Cyt-b5
PF00632--HECT
PF06701--MIB_HERC2
PF00415--RCC1
PF00569--ZZ

PRINTS

PR00633--RCCNDNSATION

SMART

SM01337--APC10
SM01117--Cyt-b5
SM00119--HECTc
SM00706--TECPR
SM00291--ZnF_ZZ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002112	Ailuropoda melanoleuca	82.72	0.00e+00	6148.00
IUUC-Atr-003065	Amborella trichopoda	34.17	1.00e-50	194.00
IUUC-Apl-003983	Anas platyrhynchos	83.44	0.00e+00	7578.00
IUUC-Aca-004300	Anolis carolinensis	83.28	0.00e+00	7474.00
IUUC-Aly-006441	Arabidopsis lyrata	33.33	4.00e-44	173.00
IUUC-Ame-010621	Astyanax mexicanus	89.95	0.00e+00	7239.00
IUUC-Bta-013067	Bos taurus	80.67	0.00e+00	7210.00
IUUC-Bdi-014093	Brachypodium distachyon	33.51	6.00e-50	192.00
IUUC-Bol-015203	Brassica oleracea	34.55	1.00e-52	202.00
IUUC-Bra-016737	Brassica rapa	34.27	6.00e-48	186.00
IUUC-Cja-019687	Callithrix jacchus	80.02	0.00e+00	7088.00
IUUC-Cfa-020672	Canis familiaris	81.09	0.00e+00	7291.00
IUUC-Cpo-021819	Cavia porcellus	78.67	0.00e+00	7017.00
IUUC-Csa-023817	Chlorocebus sabaeus	80.75	0.00e+00	7229.00
IUUC-Cho-024387	Choloepus hoffmanni	84.56	0.00e+00	1708.00
IUUC-Cin-025709	Ciona intestinalis	54.69	0.00e+00	2225.00
IUUC-Csv-026336	Ciona savignyi	59.08	0.00e+00	1450.00
IUUC-Dre-027717	Danio rerio	87.85	0.00e+00	7690.00
IUUC-Dno-029296	Dasypus novemcinctus	81.58	0.00e+00	7270.00
IUUC-Dor-030979	Dipodomys ordii	78.02	0.00e+00	2503.00
IUUC-Dme-032171	Drosophila melanogaster	59.78	0.00e+00	1540.00
IUUC-Ete-032687	Echinops telfairi	72.49	0.00e+00	2150.00
IUUC-Eca-034046	Equus caballus	80.29	0.00e+00	7217.00
IUUC-Eeu-034859	Erinaceus europaeus	86.45	0.00e+00	1794.00
IUUC-Fca-036262	Felis catus	81.17	0.00e+00	7312.00
IUUC-Fal-037562	Ficedula albicollis	83.46	0.00e+00	7529.00
IUUC-Gmo-039054	Gadus morhua	90.72	0.00e+00	1134.00
IUUC-Gga-040359	Gallus gallus	83.54	0.00e+00	7536.00
IUUC-Gac-041879	Gasterosteus aculeatus	95.20	0.00e+00	1080.00
IUUC-Ggo-044692	Gorilla gorilla	89.57	0.00e+00	4039.00
IUUC-Hsa-045995	Homo sapiens	80.79	0.00e+00	7278.00
IUUC-Hvu-047529	Hordeum vulgare	34.82	5.00e-49	189.00
IUUC-Itr-048553	Ictidomys tridecemlineatus	73.46	0.00e+00	1801.00
IUUC-Lch-049808	Latimeria chalumnae	86.89	0.00e+00	3326.00
IUUC-Lpe-051482	Leersia perrieri	33.94	1.00e-46	182.00
IUUC-Loc-052685	Lepisosteus oculatus	87.17	0.00e+00	7699.00
IUUC-Laf-053372	Loxodonta africana	80.87	0.00e+00	7233.00
IUUC-Mcc-054693	Macaca mulatta	80.75	0.00e+00	7264.00
IUUC-Meu-056660	Macropus eugenii	93.30	0.00e+00	1877.00
IUUC-Mga-059371	Meleagris gallopavo	85.11	0.00e+00	6629.00
IUUC-Mmr-060787	Microcebus murinus	81.26	0.00e+00	7316.00
IUUC-Mdo-062518	Monodelphis domestica	80.47	0.00e+00	7156.00
IUUC-Mmu-063690	Mus musculus	80.74	0.00e+00	7230.00
IUUC-Mpu-066478	Mustela putorius furo	80.49	0.00e+00	7226.00
IUUC-Mlu-067596	Myotis lucifugus	78.97	0.00e+00	3818.00
IUUC-Nle-069445	Nomascus leucogenys	74.19	0.00e+00	1578.00
IUUC-Opr-070990	Ochotona princeps	82.64	0.00e+00	2820.00
IUUC-Ont-072285	Oreochromis niloticus	92.34	0.00e+00	8053.00
IUUC-Oan-072721	Ornithorhynchus anatinus	86.92	0.00e+00	3351.00
IUUC-Ocu-074273	Oryctolagus cuniculus	80.44	0.00e+00	7187.00
IUUC-Oba-075573	Oryza barthii	33.16	2.00e-45	177.00
IUUC-Obr-076107	Oryza brachyantha	32.49	1.00e-50	194.00
IUUC-Ogl-077193	Oryza glaberrima	33.16	2.00e-45	178.00
IUUC-Ogu-078817	Oryza glumaepatula	33.16	2.00e-45	177.00
IUUC-Oin-079609	Oryza indica	32.24	4.00e-49	189.00
IUUC-Olo-080629	Oryza longistaminata	33.16	1.00e-45	178.00
IUUC-Ome-081686	Oryza meridionalis	33.16	6.00e-46	179.00
IUUC-Opu-084137	Oryza punctata	33.42	4.00e-46	180.00
IUUC-Oru-085013	Oryza rufipogon	33.16	2.00e-45	177.00
IUUC-Osa-085597	Oryza sativa	33.16	2.00e-45	177.00
IUUC-Ola-087346	Oryzias latipes	95.28	0.00e+00	1238.00
IUUC-Oga-088742	Otolemur garnettii	80.87	0.00e+00	7145.00
IUUC-Oar-090093	Ovis aries	80.68	0.00e+00	7205.00
IUUC-Ptr-091034	Pan troglodytes	78.03	0.00e+00	4876.00
IUUC-Pan-092783	Papio anubis	79.29	0.00e+00	7098.00
IUUC-Psi-094027	Pelodiscus sinensis	84.32	0.00e+00	7310.00
IUUC-Pfo-096208	Poecilia formosa	90.07	0.00e+00	6650.00
IUUC-Pab-097681	Pongo abelii	71.86	0.00e+00	1914.00
IUUC-Pop-099121	Populus trichocarpa	34.65	5.00e-51	196.00
IUUC-Pca-100705	Procavia capensis	88.24	0.00e+00	1097.00
IUUC-Pva-103147	Pteropus vampyrus	69.60	0.00e+00	1890.00
IUUC-Rno-105458	Rattus norvegicus	80.40	0.00e+00	7209.00
IUUC-Sha-106959	Sarcophilus harrisii	75.73	0.00e+00	6397.00
IUUC-Sit-109917	Setaria italica	35.76	1.00e-47	184.00
IUUC-Sly-110961	Solanum lycopersicum	34.51	3.00e-53	204.00
IUUC-Sar-113532	Sorex araneus	78.29	0.00e+00	1682.00
IUUC-Sbi-114352	Sorghum bicolor	32.56	1.00e-49	191.00
IUUC-Ssc-115337	Sus scrofa	72.64	0.00e+00	2251.00
IUUC-Tgu-116789	Taeniopygia guttata	83.34	0.00e+00	7559.00
IUUC-Tru-118129	Takifugu rubripes	95.84	0.00e+00	8447.00
IUUC-Tsy-119302	Tarsius syrichta	75.58	0.00e+00	1132.00
IUUC-Tca-121094	Theobroma cacao	35.31	3.00e-54	207.00
IUUC-Tae-124157	Triticum aestivum	32.98	2.00e-48	187.00
IUUC-Tur-126300	Triticum urartu	34.45	2.00e-49	191.00
IUUC-Tbe-128137	Tupaia belangeri	69.32	0.00e+00	1753.00
IUUC-Ttr-128273	Tursiops truncatus	77.04	0.00e+00	4197.00
IUUC-Vpa-130471	Vicugna pacos	74.74	0.00e+00	1323.00
IUUC-Xtr-132185	Xenopus tropicalis	80.31	0.00e+00	7144.00
IUUC-Xma-133233	Xiphophorus maculatus	91.34	0.00e+00	8014.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence