iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.50e-16	58.3	235	287

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +kv++lyd+ea++++eLt+ +G++++v+  ++ d +W+kg    +  +GlfP+nFv+
   Q: 235  RKVRALYDFEAAEENELTFFAGEIIHVL--DDSDPNWWKG--YNQRGEGLFPSNFVT 287
           79**************************..99********..788899*******97 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MGIFGQSSPF DADVEKATSE TNTNDNWSLI LDVCDKVTTN PRLAKDCLKA VMRRMGHTDP 60
HVVMQAITLL DALSNNCGKP LHLEVASRDF ETEFRRLLAK AQPKVSLKMR QVLKNWAEND 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCATTAGTCA TTTTTTACAC AATAAACGTA AATTAAGCGA ATTTGCAAGC GCTATTCGGA 60
AGTTTTTAGG CTAATCGAAA AGATATAAGC AGCCCAAAAG AGATTTGGAA AAAAGCGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR008942--ENTH_VHS
IPR004152--GAT_dom
IPR001452--SH3_domain
IPR003903--UIM_dom
IPR002014--VHS_dom

PROSITE

PS50002--SH3
PS50330--UIM
PS50179--VHS

Pfam

PF00018--SH3_1
PF02809--UIM
PF00790--VHS

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3
SM00726--UIM
SM00288--VHS

Gene Ontology

GO:0033565--C:ESCRT-0 complex
GO:0098793--C:presynapse
GO:0043130--F:ubiquitin binding
GO:0016197--P:endosomal transport
GO:0007427--P:epithelial cell migration, open tracheal system
GO:0006886--P:intracellular protein transport
GO:0042059--P:negative regulation of epidermal growth factor receptor signaling pathway
GO:0016322--P:neuron remodeling
GO:0007269--P:neurotransmitter secretion
GO:0045743--P:positive regulation of fibroblast growth factor receptor signaling pathway
GO:0051726--P:regulation of cell cycle
GO:0042058--P:regulation of epidermal growth factor receptor signaling pathway
GO:2000274--P:regulation of epithelial cell migration, open tracheal system
GO:0046425--P:regulation of JAK-STAT cascade
GO:0048488--P:synaptic vesicle endocytosis
GO:0042060--P:wound healing

KEGG

dme:Dmel_CG6521

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002392	Ailuropoda melanoleuca	42.48	2.00e-96	345.00
IUUC-Apl-003463	Anas platyrhynchos	40.83	9.00e-95	340.00
IUUC-Aca-005116	Anolis carolinensis	44.42	2.00e-96	345.00
IUUC-Ago-007874	Ashbya gossypii	25.09	4.00e-21	95.10
IUUC-Acl-008046	Aspergillus clavatus	30.99	1.00e-30	127.00
IUUC-Afl-008621	Aspergillus flavus	26.48	4.00e-34	138.00
IUUC-Afu-008826	Aspergillus fumigatus	29.58	2.00e-29	122.00
IUUC-Ani-009419	Aspergillus nidulans	29.90	8.00e-32	130.00
IUUC-Ang-009580	Aspergillus niger	29.35	8.00e-31	127.00
IUUC-Ate-010532	Aspergillus terreus	27.18	3.00e-33	135.00
IUUC-Ame-011220	Astyanax mexicanus	42.24	1.00e-102	366.00
IUUC-Bgr-012113	Blumeria graminis	26.35	2.00e-38	152.00
IUUC-Bta-013368	Bos taurus	44.69	3.00e-97	348.00
IUUC-Bci-013955	Botrytis cinerea	29.15	3.00e-28	119.00
IUUC-Cel-018461	Caenorhabditis elegans	34.61	2.00e-48	185.00
IUUC-Cja-019133	Callithrix jacchus	42.23	2.00e-97	348.00
IUUC-Cfa-020800	Canis familiaris	42.48	2.00e-95	342.00
IUUC-Cpo-021685	Cavia porcellus	40.32	2.00e-97	348.00
IUUC-Csa-023325	Chlorocebus sabaeus	41.99	9.00e-97	346.00
IUUC-Cho-024556	Choloepus hoffmanni	42.33	6.00e-91	327.00
IUUC-Cin-025766	Ciona intestinalis	40.07	2.00e-46	178.00
IUUC-Csv-026035	Ciona savignyi	41.85	2.00e-45	175.00
IUUC-Cgl-026648	Colletotrichum gloeosporioides	26.17	4.00e-34	138.00
IUUC-Cne-027007	Cryptococcus neoformans	34.97	3.00e-18	85.90
IUUC-Cme-027259	Cyanidioschyzon merolae	35.00	7.20e-02	31.20
IUUC-Dre-028379	Danio rerio	43.87	7.00e-99	353.00
IUUC-Dno-029288	Dasypus novemcinctus	41.34	3.00e-92	331.00
IUUC-Dor-030515	Dipodomys ordii	43.27	3.00e-82	298.00
IUUC-Dse-031527	Dothistroma septosporum	28.43	2.00e-31	129.00
IUUC-Ete-032804	Echinops telfairi	43.15	1.00e-83	303.00
IUUC-Eca-033520	Equus caballus	44.78	1.00e-91	329.00
IUUC-Eeu-034820	Erinaceus europaeus	42.98	1.00e-46	179.00
IUUC-Fca-035914	Felis catus	42.70	9.00e-97	346.00
IUUC-Fal-037355	Ficedula albicollis	39.62	6.00e-91	327.00
IUUC-Fox-037748	Fusarium oxysporum	26.55	2.00e-30	126.00
IUUC-Fso-038126	Fusarium solani	25.80	1.00e-34	140.00
IUUC-Gmo-039628	Gadus morhua	44.12	2.00e-98	352.00
IUUC-Ggr-040048	Gaeumannomyces graminis	25.89	7.00e-37	148.00
IUUC-Gga-041110	Gallus gallus	41.81	2.00e-97	348.00
IUUC-Gac-042301	Gasterosteus aculeatus	42.42	3.00e-104	370.00
IUUC-Ggo-044963	Gorilla gorilla	42.23	2.00e-97	348.00
IUUC-Hsa-046159	Homo sapiens	42.45	2.00e-97	348.00
IUUC-Itr-048399	Ictidomys tridecemlineatus	43.64	2.00e-87	314.00
IUUC-Kpa-049200	Komagataella pastoris	26.20	8.00e-22	97.40
IUUC-Lch-050447	Latimeria chalumnae	42.53	9.00e-88	316.00
IUUC-Loc-052761	Lepisosteus oculatus	44.36	2.00e-96	345.00
IUUC-Lma-053287	Leptosphaeria maculans	30.28	2.00e-33	136.00
IUUC-Laf-053662	Loxodonta africana	41.34	4.00e-95	341.00
IUUC-Mcc-055110	Macaca mulatta	42.23	4.00e-97	347.00
IUUC-Meu-056575	Macropus eugenii	39.78	1.00e-62	233.00
IUUC-Mor-056972	Magnaporthe oryzae	28.99	1.00e-32	134.00
IUUC-Mpo-057476	Magnaporthe poae	31.18	1.00e-24	107.00
IUUC-Mla-059162	Melampsora laricipopulina	33.80	6.00e-20	91.70
IUUC-Mga-060117	Meleagris gallopavo	40.24	6.00e-93	333.00
IUUC-Mvi-060560	Microbotryum violaceum	32.14	4.00e-19	89.40
IUUC-Mmr-061413	Microcebus murinus	42.21	6.00e-98	350.00
IUUC-Mdo-061951	Monodelphis domestica	41.37	1.00e-99	356.00
IUUC-Mmu-063771	Mus musculus	44.44	4.00e-99	354.00
IUUC-Mpu-066320	Mustela putorius furo	37.33	4.00e-81	294.00
IUUC-Mlu-067740	Myotis lucifugus	41.76	4.00e-93	334.00
IUUC-Nfi-068568	Neosartorya fischeri	29.93	9.00e-31	127.00
IUUC-Ncr-068765	Neurospora crassa	25.06	5.00e-35	142.00
IUUC-Nle-069083	Nomascus leucogenys	42.23	2.00e-97	348.00
IUUC-Opr-070584	Ochotona princeps	35.65	4.00e-67	248.00
IUUC-Ont-072360	Oreochromis niloticus	44.85	1.00e-101	362.00
IUUC-Oan-073093	Ornithorhynchus anatinus	43.80	6.00e-95	340.00
IUUC-Ocu-074641	Oryctolagus cuniculus	42.21	4.00e-97	347.00
IUUC-Ola-087487	Oryzias latipes	45.50	5.00e-101	360.00
IUUC-Oga-088551	Otolemur garnettii	40.39	1.00e-99	356.00
IUUC-Oar-089972	Ovis aries	44.23	6.00e-96	343.00
IUUC-Ptr-090672	Pan troglodytes	42.23	2.00e-97	348.00
IUUC-Pan-092407	Papio anubis	41.99	8.00e-97	346.00
IUUC-Psi-092953	Pelodiscus sinensis	43.00	7.00e-91	327.00
IUUC-Pma-094312	Petromyzon marinus	45.66	2.00e-87	315.00
IUUC-Pno-094911	Phaeosphaeria nodorum	32.63	4.00e-33	134.00
IUUC-Pfo-096030	Poecilia formosa	44.36	1.00e-98	352.00
IUUC-Pab-097691	Pongo abelii	42.23	2.00e-97	348.00
IUUC-Pca-100396	Procavia capensis	41.16	1.00e-51	196.00
IUUC-Pva-103120	Pteropus vampyrus	43.11	2.00e-96	345.00
IUUC-Pgr-103679	Puccinia graminis	36.21	3.00e-17	82.80
IUUC-Ptt-103709	Puccinia triticina	36.21	1.00e-17	84.00
IUUC-Pte-104251	Pyrenophora teres	26.14	4.00e-36	145.00
IUUC-Pyt-104694	Pyrenophora triticirepentis	26.18	2.00e-36	146.00
IUUC-Rno-105982	Rattus norvegicus	39.81	2.00e-97	348.00
IUUC-Sce-106209	Saccharomyces cerevisiae	26.98	4.00e-23	101.00
IUUC-Sha-106927	Sarcophilus harrisii	41.40	8.00e-101	360.00
IUUC-Sja-107859	Schizosaccharomyces japonicus	26.68	8.00e-22	97.10
IUUC-Spo-108333	Schizosaccharomyces pombe	28.06	2.00e-22	99.40
IUUC-Ssl-108525	Sclerotinia sclerotiorum	28.47	3.00e-27	115.00
IUUC-Sar-113551	Sorex araneus	42.09	2.00e-95	341.00
IUUC-Sre-115010	Sporisorium reilianum	34.75	2.00e-20	93.20
IUUC-Ssc-115322	Sus scrofa	41.72	8.00e-93	333.00
IUUC-Tgu-116550	Taeniopygia guttata	41.07	5.00e-98	350.00
IUUC-Tru-118646	Takifugu rubripes	44.47	3.00e-98	351.00
IUUC-Tsy-118874	Tarsius syrichta	41.99	1.00e-97	349.00
IUUC-Tni-120235	Tetraodon nigroviridis	44.15	8.00e-98	350.00
IUUC-Tre-122061	Trichoderma reesei	24.62	7.00e-28	118.00
IUUC-Tvi-122365	Trichoderma virens	24.94	8.00e-31	127.00
IUUC-Tme-127104	Tuber melanosporum	25.87	1.00e-30	127.00
IUUC-Tbe-127233	Tupaia belangeri	43.13	1.00e-66	246.00
IUUC-Ttr-129298	Tursiops truncatus	41.81	5.00e-96	343.00
IUUC-Uma-129613	Ustilago maydis	34.75	2.00e-20	93.20
IUUC-Vda-129759	Verticillium dahliae	26.38	5.00e-31	128.00
IUUC-Vpa-130071	Vicugna pacos	37.93	5.00e-80	290.00
IUUC-Xtr-131863	Xenopus tropicalis	42.42	1.00e-93	336.00
IUUC-Xma-132992	Xiphophorus maculatus	44.61	2.00e-99	355.00
IUUC-Yli-134599	Yarrowia lipolytica	34.75	6.00e-17	82.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence