iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106896

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01166482

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000012816.1	ENSSHAT00000015142.1	ENSSHAP00000015017.1

Status

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	1.50e-47	162.7	1505	1700

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C+vC++ ls+e+ +  l+C+h++Ck+C+++yl+++i+++ v +++cp a+cp++ +++ i+++++++e++++yek+ll+ +ve++++++w
   Q: 1505 CPVCVSPLSPEDQPPALCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTSAFIRAIVSSPEVIAKYEKALLRGYVESCSNMTW 1594
           ****************************************************************************************** PP
   S: 91   cpap.dCslvvllekeaeklevecekcgkefCveCk.eewHeglsCkelkeklakteeek...eeaeskelleanskkCpkCkvyiekne 175
           c++p +C+++++ +       + c+kcg+++C++C+  e+H ++sC+++++++++   ++    ea+sk+l++  sk+Cp+C+++iekne
   Q: 1595 CTNPqGCDRILCRQGL--GCGAACSKCGWASCFNCNfPEAHYPASCSHMSQWVDDGGYYEgmsVEAQSKHLAKLISKRCPSCQAPIEKNE 1682
           ****78******9993..56667*************8899***************9977688899************************* PP
   S: 176  gCnhmtCakCkaefCwlC 193
           gC hmtCakC++ fCw C
   Q: 1683 GCLHMTCAKCNHGFCWRC 1700
           *****************9 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

LQVLWQSTGR TYWVHWHMVE ILGPVTEDKV TTEPEKGTGI SSCLIPTVPP SLDWKPLGGL 60
YALPYLKPEA QTNTESGCLS QAEWWELLFF IKKLDGPEQQ EFLQLLQENP DGETLEEEAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCCAGGTGC TGTGGCAGTC GACAGGCCGC ACATACTGGG TGCACTGGCA CATGGTGGAG 60
ATTCTGGGTC CTGTAACTGA GGACAAAGTT ACTACTGAGC CAGAGAAAGG GACAGGAAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR004939--APC_su10/DOC_dom
IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR016150--Casein_kin_II_reg-sub_b-sht
IPR021097--CPH_domain
IPR031222--CUL9
IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR019559--Cullin_neddylation_domain
IPR008979--Galactose-bd-like
IPR002867--IBR_dom
IPR014722--Rib_L2_dom2
IPR011991--WHTH_DNA-bd_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2
PS51284--DOC
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF03256--ANAPC10
PF11515--Cul7
PF10557--Cullin_Nedd8
PF01485--IBR

SMART

SM01337--APC10
SM00884--Cullin_Nedd8
SM00647--IBR

Gene Ontology

GO:0031461--C:cullin-RING ubiquitin ligase complex
GO:0008270--F:zinc ion binding
GO:0000226--P:microtubule cytoskeleton organization
GO:0016567--P:protein ubiquitination
GO:0007088--P:regulation of mitotic nuclear division
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001405	Ailuropoda melanoleuca	68.98	0.00e+00	1202.00
IUUC-Apl-003458	Anas platyrhynchos	67.87	0.00e+00	796.00
IUUC-Aca-004815	Anolis carolinensis	64.76	0.00e+00	986.00
IUUC-Ame-010611	Astyanax mexicanus	58.08	0.00e+00	848.00
IUUC-Bta-012877	Bos taurus	75.96	0.00e+00	1145.00
IUUC-Cja-019255	Callithrix jacchus	76.04	0.00e+00	1192.00
IUUC-Cfa-020119	Canis familiaris	68.20	0.00e+00	1202.00
IUUC-Cpo-022473	Cavia porcellus	73.24	0.00e+00	1087.00
IUUC-Csa-024157	Chlorocebus sabaeus	77.24	0.00e+00	1188.00
IUUC-Cho-024879	Choloepus hoffmanni	66.67	9.00e-140	492.00
IUUC-Cin-025402	Ciona intestinalis	32.65	1.00e-110	394.00
IUUC-Dno-028904	Dasypus novemcinctus	78.11	0.00e+00	1170.00
IUUC-Dor-030234	Dipodomys ordii	71.24	2.00e-160	560.00
IUUC-Ete-032516	Echinops telfairi	60.75	0.00e+00	887.00
IUUC-Eca-034394	Equus caballus	74.91	0.00e+00	1129.00
IUUC-Eeu-035166	Erinaceus europaeus	76.10	0.00e+00	1121.00
IUUC-Fca-035740	Felis catus	68.23	0.00e+00	1199.00
IUUC-Fal-036672	Ficedula albicollis	48.82	0.00e+00	647.00
IUUC-Gmo-038795	Gadus morhua	58.87	4.00e-133	469.00
IUUC-Gga-040154	Gallus gallus	63.91	0.00e+00	889.00
IUUC-Gac-041628	Gasterosteus aculeatus	67.15	3.00e-148	520.00
IUUC-Ggo-045570	Gorilla gorilla	76.35	0.00e+00	1190.00
IUUC-Hsa-046690	Homo sapiens	77.11	0.00e+00	1185.00
IUUC-Itr-048680	Ictidomys tridecemlineatus	75.96	0.00e+00	1242.00
IUUC-Lch-049956	Latimeria chalumnae	60.61	4.00e-140	492.00
IUUC-Loc-052706	Lepisosteus oculatus	61.28	0.00e+00	875.00
IUUC-Laf-054297	Loxodonta africana	78.82	0.00e+00	644.00
IUUC-Mcc-055727	Macaca mulatta	77.11	0.00e+00	1212.00
IUUC-Meu-056074	Macropus eugenii	94.00	0.00e+00	1353.00
IUUC-Mmr-060869	Microcebus murinus	68.02	0.00e+00	1177.00
IUUC-Mdo-062902	Monodelphis domestica	95.39	0.00e+00	1642.00
IUUC-Mmu-063991	Mus musculus	74.91	0.00e+00	1188.00
IUUC-Mpu-065974	Mustela putorius furo	68.66	0.00e+00	1185.00
IUUC-Mlu-067473	Myotis lucifugus	77.04	0.00e+00	630.00
IUUC-Nle-069292	Nomascus leucogenys	76.98	0.00e+00	1180.00
IUUC-Opr-071020	Ochotona princeps	73.65	0.00e+00	811.00
IUUC-Ont-071953	Oreochromis niloticus	47.78	0.00e+00	761.00
IUUC-Oan-073534	Ornithorhynchus anatinus	71.65	0.00e+00	981.00
IUUC-Ocu-074244	Oryctolagus cuniculus	76.94	0.00e+00	1212.00
IUUC-Ola-087072	Oryzias latipes	58.70	0.00e+00	813.00
IUUC-Oga-088310	Otolemur garnettii	67.06	0.00e+00	1129.00
IUUC-Oar-090174	Ovis aries	75.46	0.00e+00	1139.00
IUUC-Ptr-091410	Pan troglodytes	77.50	0.00e+00	1192.00
IUUC-Pan-091856	Papio anubis	67.55	0.00e+00	1167.00
IUUC-Pma-094192	Petromyzon marinus	47.10	3.00e-177	616.00
IUUC-Pfo-096773	Poecilia formosa	60.87	0.00e+00	785.00
IUUC-Pab-098635	Pongo abelii	76.75	0.00e+00	1142.00
IUUC-Pca-100539	Procavia capensis	78.33	0.00e+00	1169.00
IUUC-Pva-102813	Pteropus vampyrus	71.18	0.00e+00	1076.00
IUUC-Rno-106105	Rattus norvegicus	75.55	0.00e+00	1187.00
IUUC-Sar-113132	Sorex araneus	63.98	0.00e+00	905.00
IUUC-Ssc-116000	Sus scrofa	75.49	0.00e+00	1176.00
IUUC-Tgu-116915	Taeniopygia guttata	72.09	3.00e-54	205.00
IUUC-Tru-118013	Takifugu rubripes	55.98	0.00e+00	811.00
IUUC-Tsy-118860	Tarsius syrichta	73.25	9.00e-165	574.00
IUUC-Tni-120062	Tetraodon nigroviridis	58.31	0.00e+00	858.00
IUUC-Tbe-127660	Tupaia belangeri	70.13	1.00e-124	441.00
IUUC-Ttr-128780	Tursiops truncatus	65.56	0.00e+00	1078.00
IUUC-Vpa-130086	Vicugna pacos	67.18	1.00e-138	487.00
IUUC-Xtr-132882	Xenopus tropicalis	59.53	0.00e+00	830.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence