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Tag Content
UUCD2 ID IUUC-Mcc-055822
UUCD1 version UUC-MaM-00687
Ensembl Protein ID ENSMMUP00000021052.3
UniProt Accession F7FVG8; F7FVG8_MACMU
Genbank Protein ID ENSMMUP00000021052
Protein Name Uncharacterized protein
Genbank Nucleotide ID JSUE03037502
Gene Name FBXW11
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMMUG00000016008.3 ENSMMUT00000063752.1 ENSMMUP00000046046.1
ENSMMUG00000016008.3 ENSMMUT00000078012.1 ENSMMUP00000049952.1
ENSMMUG00000016008.3 ENSMMUT00000058175.1 ENSMMUP00000046652.1
ENSMMUG00000016008.3 ENSMMUT00000022506.3 ENSMMUP00000021054.2
ENSMMUG00000016008.3 ENSMMUT00000022503.3 ENSMMUP00000021052.3
ENSMMUG00000016008.3 ENSMMUT00000022504.3 ENSMMUP00000021053.3
ENSMMUG00000016008.3 ENSMMUT00000068480.1 ENSMMUP00000046920.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.20e-57 190.3 471 505
UBD/Beta-Prp 2.30e-68 231.7 384 549
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclafsd.tllvsGsdDgtikvWDlrtgvl 35
           gH++ v+c++f d +++vsG++Dg+ikvWDl    +
   Q: 471  GHEELVRCIRF-DnKRIVSGAYDGKIKVWDLQAALD 505
           8**********.44****************977665 PP
   

   UBD/Beta-Prp
   S: 43   kllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee 131
           +l r l gh a+v+ v+f+++  ++v++s Drtikvw+ st++ v+tl+gh++ + +l++      +vsGs+d+tir+wd+e g cl+ 
   Q: 384  TLRRVLVGHRAAVNVVDFDDK--YIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLR- 467
           4555679*************9..8**************************************..************************. PP
   S: 132  tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.........ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
           +l+gh+++v+c++++   + +vsG++D+++++Wdl         ++  +lrtl + h ++v  l+fd+  ++++s s+d t+ +wd+
   Q: 468  VLEGHEELVRCIRFDN--KRIVSGAYDGKIKVWDLqaaldprapASTLCLRTLVE-HSGRVFRLQFDE--FQIISSSHDDTILIWDF 549
           ***************9..***********************************99.************..99**************7 PP
   
Organism Macaca mulatta
Protein Sequence
(Fasta)
QTNQSLKFWL SPPLSLWLGC ANLVESMCAL SCLQSMPSVR CLQNTSVMED QNEDESPKKN 60
TLWQVGMTAH RLDNRMLPQL INGTSSVIVS RKRPSEGNYQ KEKDLCIKYF DQWSESDQVE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mcc-055822|E3,WD_repeat;UBD,Beta-Prp|Macaca mulatta
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGTGGCGCTC TCGAGGCCCT ACCATGAGCA AGCTCTTAAC TCTTCAGGTG TGCAAGTCCT 60
ACGTCCACAG TCCAGTGCTA CTGTCAGCTT GGAGTTCAGC TTCGGGCTGC CAAGAGCCAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mcc-055822|E3,WD_repeat;UBD,Beta-Prp|Macaca mulatta
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0732--Signal
KW-0853--WD repeat
Interpro

IPR021977--Beta-TrCP_D
IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF12125--Beta-TrCP_D
PF12937--F-box-like
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM01028--Beta-TrCP_D
SM00256--FBOX
SM00320--WD40
Gene Ontology

GO:0005813--C:centrosome
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0042347--P:negative regulation of NF-kappaB import into nucleus
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0042753--P:positive regulation of circadian rhythm
GO:0045862--P:positive regulation of proteolysis
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006470--P:protein dephosphorylation
GO:0031648--P:protein destabilization
GO:0000209--P:protein polyubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001397 Ailuropoda melanoleuca 91.58 0.00e+00 1063.00
IUUC-Apl-003449 Anas platyrhynchos 95.74 0.00e+00 1102.00
IUUC-Ang-009766 Aspergillus niger 31.12 5.00e-52 199.00
IUUC-Ame-011174 Astyanax mexicanus 83.42 0.00e+00 983.00
IUUC-Bta-012920 Bos taurus 95.71 0.00e+00 1052.00
IUUC-Cel-018392 Caenorhabditis elegans 63.16 0.00e+00 635.00
IUUC-Cja-018879 Callithrix jacchus 91.58 0.00e+00 1063.00
IUUC-Cfa-020021 Canis familiaris 91.58 0.00e+00 1063.00
IUUC-Cpo-022151 Cavia porcellus 96.41 0.00e+00 1044.00
IUUC-Csa-024095 Chlorocebus sabaeus 96.76 0.00e+00 1044.00
IUUC-Cho-024658 Choloepus hoffmanni 83.16 1.00e-138 486.00
IUUC-Dre-028160 Danio rerio 88.28 0.00e+00 961.00
IUUC-Dno-029485 Dasypus novemcinctus 86.49 0.00e+00 920.00
IUUC-Dor-030498 Dipodomys ordii 92.35 0.00e+00 1052.00
IUUC-Eca-033804 Equus caballus 99.60 0.00e+00 1019.00
IUUC-Fca-035887 Felis catus 96.61 0.00e+00 1054.00
IUUC-Fal-036783 Ficedula albicollis 96.34 0.00e+00 1082.00
IUUC-Gmo-038590 Gadus morhua 81.93 0.00e+00 939.00
IUUC-Gga-040628 Gallus gallus 95.97 0.00e+00 1076.00
IUUC-Gac-041305 Gasterosteus aculeatus 82.98 0.00e+00 958.00
IUUC-Ggo-044604 Gorilla gorilla 91.58 0.00e+00 1063.00
IUUC-Hsa-046139 Homo sapiens 91.58 0.00e+00 1063.00
IUUC-Lch-050460 Latimeria chalumnae 93.76 0.00e+00 1023.00
IUUC-Laf-053968 Loxodonta africana 95.26 0.00e+00 1117.00
IUUC-Mga-059225 Meleagris gallopavo 95.85 0.00e+00 1036.00
IUUC-Mvi-060284 Microbotryum violaceum 44.95 2.00e-69 257.00
IUUC-Mmr-060746 Microcebus murinus 91.58 0.00e+00 1063.00
IUUC-Mdo-062005 Monodelphis domestica 96.19 0.00e+00 1040.00
IUUC-Mmu-063851 Mus musculus 94.56 0.00e+00 1110.00
IUUC-Mpu-065716 Mustela putorius furo 96.05 0.00e+00 1049.00
IUUC-Mlu-067001 Myotis lucifugus 96.76 0.00e+00 1044.00
IUUC-Nle-069788 Nomascus leucogenys 100.00 0.00e+00 1018.00
IUUC-Opr-071229 Ochotona princeps 91.40 0.00e+00 1061.00
IUUC-Ont-071792 Oreochromis niloticus 83.16 0.00e+00 965.00
IUUC-Oan-072782 Ornithorhynchus anatinus 96.34 0.00e+00 1082.00
IUUC-Ocu-074894 Oryctolagus cuniculus 95.26 0.00e+00 1117.00
IUUC-Ola-086985 Oryzias latipes 84.82 0.00e+00 991.00
IUUC-Oga-088604 Otolemur garnettii 90.16 0.00e+00 1055.00
IUUC-Oar-090412 Ovis aries 96.89 0.00e+00 1088.00
IUUC-Ptr-091039 Pan troglodytes 91.40 0.00e+00 1061.00
IUUC-Pan-092770 Papio anubis 95.07 0.00e+00 1068.00
IUUC-Psi-093887 Pelodiscus sinensis 94.88 0.00e+00 1100.00
IUUC-Pno-094808 Phaeosphaeria nodorum 29.50 1.00e-45 177.00
IUUC-Pfo-096783 Poecilia formosa 85.17 0.00e+00 992.00
IUUC-Pva-102547 Pteropus vampyrus 91.40 0.00e+00 1056.00
IUUC-Rno-105246 Rattus norvegicus 96.15 0.00e+00 1081.00
IUUC-Sha-107339 Sarcophilus harrisii 96.19 0.00e+00 1040.00
IUUC-Sja-107743 Schizosaccharomyces japonicus 35.38 5.00e-74 271.00
IUUC-Tgu-116541 Taeniopygia guttata 95.73 0.00e+00 1104.00
IUUC-Tru-117671 Takifugu rubripes 84.29 0.00e+00 986.00
IUUC-Tni-120359 Tetraodon nigroviridis 87.05 0.00e+00 943.00
IUUC-Tbe-127418 Tupaia belangeri 87.01 0.00e+00 974.00
IUUC-Ttr-129131 Tursiops truncatus 91.58 0.00e+00 1063.00
IUUC-Vpa-130668 Vicugna pacos 91.58 0.00e+00 1061.00
IUUC-Xma-133187 Xiphophorus maculatus 95.36 5.00e-158 550.00
Created Date 25-Jun-2017

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